Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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2',3'-Didehydro-3'-dideoxy-thymidine-5'-monophosphate, lithium salt
2',3'-Didehydro-3'-dideoxy-thymidine-5'-monophosphate, lithium salt is a novel antiviral nucleoside analog that inhibits the synthesis of DNA. The drug is currently being studied to treat herpes simplex virus infections. It has been shown to inhibit viral replication in vitro and in vivo, and to induce reactivation of latent virus. 2',3'-Didehydro-3'-dideoxy-thymidine-5'-monophosphate, lithium salt also has anticancer activity by inhibiting DNA synthesis and inducing apoptosis via activation of the caspase cascade.
2',3'-Didehydro-3'-dideoxy-thymidine-5'-monophosphate, lithium salt is a modified nucleoside analog that is synthesized from 3’,5’-O-(1H-tetrazole)-2’,4’,6Pureza:Min. 95%3'-Azido-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine
3'-Azido-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine is a synthetic nucleoside that belongs to the group of modified nucleosides. It is a phosphoramidite that has been shown to be an effective antiviral and anticancer agent. 3'-Azido-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine inhibits viral replication by interfering with DNA synthesis and repair, which is necessary for viral reproduction. The compound has also been shown to inhibit tumor cell growth in vitro and induce apoptosis in vivo.Fórmula:C38H34N8O6Pureza:Min. 95%Peso molecular:698.73 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-methylguanosine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-0-DMT-N2-methylguanosine 3'-CE phosphoramidite can be used as a building block for the incorporation of N2-methylguanosine (m2G) into oligoribonucleotides by standard automated RNA solid-phase synthesis. Nucleosides that are methylated at their nucleobase account for the second largest number of naturally occurring nucleoside modifications after 2’-O methylation. They are encountered in all major RNA species, such as tRNA, rRNA, snRNA and mRNA.Fórmula:C47H64N7O8PSiPureza:Min. 95%Peso molecular:914.11 g/mol2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate sodium salt
CAS:2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate sodium salt is a novel nucleoside phosphoramidite that is used in the synthesis of DNA. It has antiviral and anticancer properties, and it inhibits viral replication and also induces apoptosis in cancer cells. 2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate sodium salt has been shown to inhibit HIV replication with an IC50 value of 0.5 mM. It specifically targets HIV reverse transcriptase, which is responsible for the conversion of RNA into DNA during the early stages of infection. The compound also inhibits cellular proliferation and induces apoptosis in cancer cells, including prostate cancer cells.Fórmula:C10H16FN2O14P3Pureza:Min. 95%Peso molecular:500.16 g/mol2-Amino-6-mercapto-9-(2',3',5'-tri-O-acetyl-b-ribofuranosyl)purine
CAS:2-Amino-6-mercapto-9-(2',3',5'-tri-O-acetyl-b-ribofuranosyl)purine (2AMAP) is an Activator that belongs to the group of nucleosides. It is a novel, modified nucleoside consisting of 2'-deoxyribonucleosides and phosphoramidites. 2AMAP has been shown to inhibit the proliferation of cancer cells and HIV viruses. This drug also has antiviral properties and can be used as a chemotherapeutic agent for the treatment of diseases such as chronic hepatitis B or C, cytomegalovirus or herpes virus infection. 2AMAP is highly purified, with a purity level of >99%.Fórmula:C16H19N5O7SPureza:Min. 95%Peso molecular:425.42 g/mol2'-Deoxycytidine-5'-O-(1-thiotriphosphate) lithium salt
CAS:2'-Deoxycytidine-5'-O-(1-thiotriphosphate) lithium salt (dCTPTP) is a nucleotide analogue that inhibits DNA replication. It is a substrate for DNA polymerase and can be incorporated into the growing strand of DNA. This drug has been shown to inhibit the replication of retroviruses, such as murine leukemia virus and human immunodeficiency virus type 1, in tissue cultures with relatively low concentrations. It also inhibits dengue virus when present at high concentrations. 2'-Deoxycytidine-5'-O-(1-thiotriphosphate) lithium salt has been used to study the mechanism of transcription-polymerase chain reactions by inhibiting RNA synthesis in vitro and in vivo.
Fórmula:C9H16N3O12P3S·Li4Pureza:Min. 95%Peso molecular:506.95 g/molN6-Benzyl-5'-ethylcarboxamidoadenosine
CAS:N6-Benzyl-5'-ethylcarboxamidoadenosine is a novel nucleoside that has shown anticancer and antiviral activity. It is one of the first phosphoramidites to be synthesized in high purity, and it can be used as an activator for ribonucleoside synthesis. This compound also has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.
Fórmula:C19H22N6O4Pureza:Min. 95%Peso molecular:398.42 g/mol6-Amino-9-(2',3',5'-tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)purine
6-Amino-9-(2',3',5'-tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)purine is a novel nucleoside analog that has been modified to include a 2'-C methyl group at the 5' position. This modification prevents the formation of an undesired phosphodiester linkage between the nucleotide and ribonucleotide moieties, which can lead to degradation of the drug. The purine base is attached at the 3' position, which is important for its antiviral activity. 6-Amino-9-(2',3',5'-tri-O-benzoyl-2'-C-methylbDribofuranosyl)purine is active against DNA viruses and has anticancer properties.Fórmula:C32H27N5O7Pureza:Min. 95%Peso molecular:593.6 g/mol5-[N-(6-Aminohexyl)-3-E-acrylamido]-2'-deoxy-5'-O-DMT-uridine
CAS:5-[N-(6-Aminohexyl)-3-E-acrylamido]-2'-deoxy-5'-O-DMT-uridine is a novel, activator ribonucleoside derived from the modified nucleosides 5-[N-(6-aminohexyl)-3-E-acrylamido]-2'-deoxyadenosine and 2'-deoxyuridine. It has been shown to be an effective anticancer, antiviral and antiparasitic agent. 5-[N-(6-Aminohexyl)-3-E-acrylamido]-2'-deoxy-5'-O-DMT-uridine has exhibited anticancer activity against human leukemia cells in culture, inhibiting DNA synthesis by blocking the enzyme DNA polymerase. This novel compound also blocks viral replication by inhibiting the synthesis of RNA by an enzyme called RNA polymerase II.Fórmula:C39H46N4O8Pureza:Min. 95%Peso molecular:698.82 g/mol3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine N4-succinate
3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine N4-succinate is a novel modified nucleoside that is activated by diphosphate. It is an antiviral agent that inhibits the synthesis of viral DNA and RNA. 3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine N4-succinate may be used as a chemotherapeutic agent for cancer treatment. The chemical name for this compound is 5,6,7,8,-tetrahydro-[1,2,4]triazolo[4,3a][1,4]benzodiazepin-[1,2a]-one 3'N4-(N',N',N'')-trisuccinoyl ester (3'azido) 2',3'-dideoxyadenosine 5'Pureza:Min. 95%2',3'-Di(9-phenylxanthen-9-yl)dithiouridine
CAS:2',3'-Di(9-phenylxanthen-9-yl)dithiouridine is a synthetic nucleoside that has antiviral, anticancer and antitumor properties. It is an activator of the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 2',3'-Di(9-phenylxanthen-9-yl)dithiouridine is used as a monophosphate or diphosphate for the treatment of cancer and HIV/AIDS. This drug has shown high purity and quality and can be synthesized in high yield.Fórmula:C47H36N2O6S2Pureza:Min. 95%Peso molecular:788.93 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 2000 Å
N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 2000 Å, a novel nucleoside analog, is an antiviral agent that inhibits the synthesis of viral DNA. It also induces apoptosis and cell cycle arrest in cancer cells. N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 2000 Å is synthesized by the coupling of deoxyribonucleotide phosphoramidite monomers onto a carrier support with a molecular weight of 2000Å. This product is available as white solid, and it has purity greater than 99%.Pureza:Min. 95%Adenosine 3',5'-cyclic monophosphothioate Rp-isomer triethylammonium salt
CAS:Adenosine 3',5'-cyclic monophosphothioate Rp-isomer triethylammonium salt is a neurotrophic factor that can be used in the treatment of neurological disorders. It has been shown to activate various biological processes, such as neurotransmitter release and neurite outgrowth. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer triethylammonium salt also has been shown to have an effect on body mass index (BMI) and colony stimulating factor (CSF). It stimulates the production of IGF-I, which is involved in the regulation of metabolic processes and has a positive effect on cell proliferation. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer triethylammonium salt also has been shown to stimulate signal pathways that are involved in apoptosis and neuronal differentiation.Fórmula:C10H11N5O5PS·C6H16NPureza:Min. 95%Peso molecular:446.46 g/molStavudine 5'-triphosphate triethyammonium salt
CAS:Stavudine 5'-triphosphate triethyammonium salt is a novel, modified nucleoside that has antiviral and anticancer properties. It is synthesized as a phosphoramidite and used in the synthesis of ribonucleotides, which are incorporated into RNA. Stavudine 5'-triphosphate triethyammonium salt inhibits viral DNA replication by inhibiting the activity of reverse transcriptase, an enzyme that copies the DNA sequence to create a complementary RNA sequence. In vitro studies have shown that stavudine 5'-triphosphate triethyammonium salt inhibits cell proliferation in human cancer cells.Pureza:Min. 95%Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS:Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is a high purity chemical substance. It is an antiviral and anticancer agent, which has been shown to inhibit the replication of DNA in vitro. Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid can be used for the synthesis of ribonucleosides, deoxyribonucleosides, nucleoside phosphoramidites, diphosphate and triphosphate. This novel chemical substance is also a potential inhibitor of DNA polymerase and RNA polymerase.Fórmula:C7H5N3O2Pureza:Min. 95%Peso molecular:163.13 g/mol5'-O-DMT-2'-O-(2-methylacetamido)-5-methyluridine
5'-O-DMT-2'-O-(2-methylacetamido)-5-methyluridine is a monophosphate of deoxyribonucleosides. It is an antiviral and anticancer agent that inhibits the synthesis of RNA in cells, which can lead to the death of the cell. The novel chemical structure of 5'-O-DMT-2'-O-(2-methylacetamido)-5-methyluridine makes it a useful drug for treatment against viral infections and cancer.Pureza:Min. 95%Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-biotin triethylammonium salt - 1 mM aqueous solution (10 mM Tris-HCl)
Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-biotin triethylammonium salt - 1 mM aqueous solution (10 mM Tris-HCl) is a nucleoside phosphate activator with antiviral effects. It has been successfully synthesized and shown to be an effective anticancer agent. Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-biotin triethylammonium salt - 1 mM aqueous solution (10 mM Tris-HCl) is modified from cytidine, which contains the amino acid L-alanine in place of D-alanine. This modification increases the stability and bioavailability of this molecule. Cytidine, or cytidylate, is a nucleoside phosphate that is widely used in biochemistry as an activator for other nucleosides or as a substrate for enzymesFórmula:C25H42N6O13P2S1Pureza:Min. 95%Cor e Forma:Colorless PowderPeso molecular:728.65 g/mol5'-o-Methyl-dt cep
CAS:5'-o-Methyl-dt cep is a modified phosphoramidite that has been synthesized to provide a novel, highly active anticancer and antiviral agent. It is used as an activator for the synthesis of DNA or RNA in the nucleoside or deoxyribonucleoside pathway. 5'-o-Methyl-dt cep could be used in the treatment of HIV, Hepatitis C, and other viral infections.Fórmula:C20H33N4O6PPureza:Min. 95%Peso molecular:456.5 g/mol6-Thioguanosine-5'-O-diphosphate sodium salt - 10mM aqueous solution
CAS:6-Thioguanosine-5'-O-diphosphate sodium salt is a nucleotide derivative of guanosine that binds to the regulatory site of ATP synthase in the chloroplast. It is an allosteric inhibitor that has been shown to inhibit the synthesis of proteins and chlorophyll, as well as ATP synthesis in plastids of plants. 6-Thioguanosine-5'-O-diphosphate sodium salt has been shown to be effective at inhibiting protein synthesis in mammalian cells, which may be due to its ability to bind to the metabotropic glutamate receptor. The molecule was also found to bind with high affinity to a ternary complex that includes glutamine, glutamate, and ammonia.Fórmula:C10H15N5O10P2SxNaPureza:Min. 95%Cor e Forma:PowderPeso molecular:459.27 g/molN6-Benzoyl-3'-O-tert-butyldimethylsilyl-adenosine 2'-CE phosphoramidite
N6-Benzoyl-3'-O-tert-butyldimethylsilyl-adenosine 2'-CE phosphoramidite is a novel nucleoside that has been synthesized and characterized. It is an antiviral agent and has been demonstrated to have anticancer properties. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-adenosine 2'-CE phosphoramidite is a phosphoramidite and is used in DNA synthesis as a replacement for diphosphate, which can be toxic when it reacts with ribonucleotides or deoxyribonucleotides. This novel nucleoside also inhibits the enzyme DNA polymerase, which is required for viral replication.Fórmula:C53H66N7O8PSiPureza:Min. 95%Peso molecular:988.19 g/mol
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