Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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N-(tert-butylphenoxyacetyl)-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite
N-(tert-butylphenoxyacetyl)-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is a novel nucleoside analogue with antiviral and anticancer activity. This compound is a modified nucleoside with a diphosphate group at the 5' position, which makes it resistant to viral and bacterial nucleases. N-(tert-butylphenoxyacetyl)-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite also inhibits DNA synthesis and can induce apoptosis in cancer cells. The high purity of this product allows for its use in research, drug discovery, and other applications.Fórmula:C53H64N7O10PPureza:Min. 95%Peso molecular:990.09 g/mol2'-Deoxy-5'-O-DMT-nebularine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-nebularine 3'-CE phosphoramidite is an anticancer agent that is used in the treatment of leukemia. It inhibits DNA and RNA synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. 2'-Deoxy-5'-O-DMT-nebularine 3'-CE phosphoramidite has been shown to be effective against leukemia cells that are resistant to other anticancer drugs such as 5FU. This drug has also been found to be a novel activator of caspase 3, which may be useful in apoptosis induction.Fórmula:C40H47N6O6PPureza:Min. 95%Peso molecular:738.81 g/mol2,6-Diamino-9-(2'[2-methylacetamido]-b-D-ribofuranosyl)purine
2,6-Diamino-9-(2'[2-methylacetamido]-b-D-ribofuranosyl)purine is an antiviral drug that is an analogue of adenosine. It has been shown to be a potent activator of the immune system and also has anticancer properties. 2,6-Diamino-9-(2'[2-methylacetamido]-b-D-ribofuranosyl)purine is synthesized from 2',3'-dideoxyadenosine and 2,6 diaminopurine riboside by the use of activated phosphoramidites in a modified nucleoside synthesizer. The CAS number for this compound is 70717-54-8.Pureza:Min. 95%2',3'-Dideoxyadenosine-5'-monophosphate
CAS:2',3'-Dideoxyadenosine-5'-monophosphate (ddAMP) is an adenosine analog that is a substrate for the enzyme dideoxyribonucleoside kinase. It is activated by phosphorylation to the 5' ends of DNA molecules and inhibits viral replication. ddAMP has been shown to be effective in treating human immunodeficiency virus (HIV) infection, at least in part, by inhibiting the production of p24 antigen levels and reducing the number of CD4+ lymphocytes. The mechanism of action may involve binding to HIV-1 RNA, which prevents it from interacting with cellular dsDNA and inhibits its transcription into DNA.Fórmula:C10H14N5O5PPureza:Min. 95%Peso molecular:315.22 g/mol5-Bromo-2'-O-tert-butylbutyldimethylsilyl-5'-O-DMT-uridine 3'-CE phosphoramidite
5-Bromo-2'-O-tert-butylbutyldimethylsilyl-5'-O-DMT-uridine 3'-CE phosphoramidite is a novel phosphoramidite that can be used in the synthesis of ribonucleosides. Ribonucleoside are modified nucleosides that are important for the production of RNA. This synthetic phosphoramidite has antiviral and anticancer activities, as well as other properties. It is also useful for the production of deoxyribonucleosides, which are necessary for DNA synthesis and repair. 5-Bromo-2'-O-tert-butylbutyldimethylsilyl-5'-O-DMT-uridine 3'-CE phosphoramidite is a high purity, high quality compound that can be used to synthesize nucleic acids.Fórmula:C45H60BrN4O9PSiPureza:Min. 95%Peso molecular:939.97 g/mol8-Allyloxy-N2-isobutyryl-2-deoxyguanosine
CAS:8-Allyloxy-N2-isobutyryl-2-deoxyguanosine is an anticancer drug that has been modified to be resistant to degradation by nucleases. It is a novel deoxyribonucleoside that can be converted into DNA monophosphate and phosphoramidites. 8-Allyloxy-N2-isobutyryl-2-deoxyguanosine is able to inhibit the synthesis of viral RNA and diphosphate, as well as the production of ribonucleosides and diphosphate. It also has antiviral properties, inhibiting the production of HIV RNA and HIV protein synthesis.Fórmula:C17H23N5O6Pureza:Min. 95%Peso molecular:393.40 g/mol3'-Azido-5'-O-benzoyl-2',3'-dideoxyuridine
3'-Azido-5'-O-benzoyl-2',3'-dideoxyuridine is a novel nucleoside that is synthesized by reacting 3'-azido-5'-deoxyuridine with 5-(benzoyl)salicylic acid. The compound has been shown to be an activator of DNA synthesis, to have antiviral activity, and to inhibit the growth of tumor cells in vitro. 3'-Azido-5'-O-benzoyl-2',3'-dideoxyuridine is a nucleoside analogue that may be useful in anticancer therapy.
Fórmula:C16H15N5O5Pureza:Min. 95%Peso molecular:357.32 g/mol6-Chloro-N-phenyl-9-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-9H-purin-2-amine
CAS:6-Chloro-N-phenyl-9-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-9H-purin-2-amine is a monophosphate nucleoside analog. It is an antiviral agent that inhibits the synthesis of DNA and RNA. 6CNP has been shown to be cytotoxic against cancer cells in vitro, as well as in vivo. This compound also shows anticancer activity by inhibiting the production of ribonucleosides and deoxyribonucleosides.Fórmula:C22H22ClN5O7Pureza:Min. 95%Peso molecular:503.89 g/mol4-Amino-2-methoxypyrimidine
CAS:4-Amino-2-methoxypyrimidine is a fluorescent compound that is used for the detection of hydrogen bonds, and as a precursor in the synthesis of other compounds. 4-Amino-2-methoxypyrimidine has been shown to be able to absorb ultraviolet radiation, which leads to its fluorescence. The compound can also form hydrogen bonds with other molecules and it has been shown to react with n-hexane. 4-Amino-2-methoxypyrimidine reacts with orthophosphate, producing singlet oxygen and transferring a proton. It also reacts with solvents such as water or ethanol, giving off light.Fórmula:C5H7N3OPureza:Min. 95%Peso molecular:125.13 g/mol2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine
CAS:2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is an activator, anticancer, monophosphate nucleoside that is synthesized from 2'-deoxycytidine and 5'-fluorouracil. It is a novel deoxynucleoside that has been modified to be resistant to nucleases. This product can be used in the synthesis of oligonucleotides for use as antiviral or antineoplastic agents. 2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is also known by its CAS number 1341231-51-3.Fórmula:C19H26FN3O8Pureza:Min. 95%Peso molecular:443.42 g/mol2'-Deosy-O6-diphenylcarbamoyl-5'-O-DMT-N2-isobutyrylguanine
2'-Deoxy-2'-O-diphenylcarbamoyl-5'-O-DMT-N2-isobutyrylguanine (2'-DPCG) is a novel antiviral and anticancer agent. It has been shown to inhibit the replication of both DNA and RNA viruses. 2'-DPCG is synthesized in a high yield and purified to near homogeneity. The purity of this product was confirmed by mass spectrometry analysis. The CAS number for this product is 1227071-12-0.Pureza:Min. 95%N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine
N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a nucleoside with anticancer, antiviral, and antiretroviral properties. It is synthesized by reacting cytidine with benzoyl chloride in the presence of tert-butyldimethylsilyl chloride. N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMTcytidine has shown to be a novel and potent inhibitor of the human immunodeficiency virus type 1 (HIV1) reverse transcriptase. It also inhibits DNA synthesis and has been shown to inhibit tumor cell growth in vitro.Fórmula:C43H49N3O8SiPureza:Min. 95%Peso molecular:763.95 g/mol2'-Deoxycytidine-3'-monophosphate ammonium salt
CAS:2'-Deoxycytidine-3'-monophosphate ammonium salt is a synthetic compound that is used in the production of phosphite fertilizers. It is also used to detect the presence of phosphorus and sulfur in elements, as well as to synthesize alkylene compounds. In addition, 2'-Deoxycytidine-3'-monophosphate ammonium salt can be used in the synthesis of ribozymes and deoxyadenosyl compounds.Fórmula:C9H14N3O7P·2NH3Pureza:Min. 95%Peso molecular:341.26 g/mol2’,3’-Dideoxy-5-fluorocytidine
CAS:2’,3’-Dideoxy-5-fluorocytidine is a nucleoside analog that inhibits the growth of tumor cells in animals. It has been shown to inhibit the replication of hepatitis B virus and HIV without affecting normal cell division. 2′,3′-Dideoxy-5-fluorocytidine also has potent antitumor activity against human hematopoietic cells and induces apoptosis.
Fórmula:C9H12FN3O3Pureza:Min. 95%Peso molecular:229.21 g/mol5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine
CAS:5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine is a phosphoramidite nucleoside analog that inhibits viral replication. It has shown antiviral activity against HIV type 1, HIV type 2 and herpes simplex virus type 1. 5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine is an analogue of the natural nucleoside uridine and is used in the synthesis of modified DNA and RNA molecules. This product has not been tested for carcinogenicity or mutagenicity, but it has shown anticancer properties in vitro.Fórmula:C25H22Cl2N2O7Pureza:Min. 95%Peso molecular:533.36 g/mol1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-[uracil-1-yl]-D-glucitol
CAS:1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-[uracil-1-yl]-D-glucitol is a synthetic nucleoside that is used as an antiviral agent. This compound is a potent inhibitor of human immunodeficiency virus (HIV) reverse transcriptase and has been shown to be active against influenza A virus. 1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-[uracil]-D glucitol is also an anticancer agent that inhibits DNA synthesis in cancer cells. As a modified nucleoside with a sugar group at the 5' position, this compound inhibits the incorporation of uridine into DNA by competitively inhibiting ribonucleotide reductase.Fórmula:C17H18N2O5Pureza:Min. 95%Peso molecular:330.34 g/mol1-(5',6'-Dideoxy-6'-dimethylphosphono-2'-O-(2-methoxyethyl)-5-methyl-b-D-ribo-hex-5(E)-enofuranosyl)uracil 3'-CE phosphoroamidite
1-(5',6'-Dideoxy-6'-dimethylphosphono-2'-O-(2-methoxyethyl)-5-methyl-b-D-ribo-hex-5(E)-enofuranosyl)uracil 3'-CE phosphoroamidite is a novel nucleoside analogue that has antiviral activity. It is an analog of uridine, which can be used to inhibit the synthesis of viral RNA and DNA, as well as to treat cancer. This compound is synthesized by reacting 5',6'-dideoxyuridine with 2'-O-(2-methoxyethyl)trimethylsilylchloride in the presence of triethylamine, followed by treatment with trimethylsilyl triflate. The resulting product can be purified with chromatography on silica gel and the 1H NMR spectrum exhibits signals at δ 7.06 (d, J = 8 Hz) andFórmula:C25H42N4O10P2Pureza:Min. 95%Peso molecular:620.57 g/mol2',3',5'-Tri-O-acetyl-2N,2N-dimethylguanosine
CAS:2',3',5'-Tri-O-acetyl-2N,2N-dimethylguanosine (TAMG) is a novel nucleoside that is synthesized from 2',3',5'-tri-O-acetyl-1,3,5-trioxohexanecarboxylic acid. TAMG has been shown to inhibit HIV and Hepatitis B virus replication by inhibiting the synthesis of viral DNA and RNA. The antiviral properties of TAMG are due to its incorporation into the growing DNA chain and blocking the polymerization process. TAMG also has anticancer activity and can be used as a chemotherapeutic agent against various types of cancer cells.Fórmula:C18H23N5O8Pureza:Min. 95%Peso molecular:437.4 g/mol2'-Deoxy-5'-O-DMT-5-(3-methacryloyl)uridine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-5-(3-methacryloyl)uridine 3'-CE phosphoramidite is a synthetic nucleoside analogue. It is an antiviral and anticancer agent that inhibits viral DNA synthesis by inhibiting the enzyme DNA polymerase. The compound also induces apoptosis in cancer cells by inhibiting RNA synthesis. 2'-Deoxy-5'-O-DMT-5-(3-methacryloyl)uridine 3'-CE phosphoramidite has been shown to be cytotoxic to human breast cancer cells, and is currently being studied as a potential treatment for prostate cancer.Fórmula:C43H51N4O10PPureza:Min. 95%Peso molecular:814.88 g/mol2'-Deoxyadenosine-5'-triphosphate dilithium salt
2'-Deoxyadenosine-5'-triphosphate dilithium salt is a modified nucleoside that is used in the synthesis of DNA. It can be used as an antiviral agent and it also has anticancer properties. This compound is synthesized by reacting adenosine triphosphate with lithium diisopropylamide to form the 5' phosphate of 2'-deoxyadenosine. The resulting nucleotide is then reacted with lithium diisopropylamide, followed by dilithium metal to form the desired product. The high quality and purity of this compound make it ideal for use in research and development or for clinical applications.Fórmula:C10H13N5O12P3·2LiPureza:Min. 95%Peso molecular:502.04 g/mol
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