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Nucleosídeos

Nucleosídeos

Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.

Foram encontrados 3567 produtos de "Nucleosídeos"

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  • 5'-O-p-Anisoylthymidine


    <p>5'-O-p-Anisoylthymidine is a novel activator and ribonucleoside that has been synthesized by modifying the structure of thymidine. This compound is active against cancer and antiviral, such as herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, influenza A/PR/8/34 (H1N1), and influenza B/Yamagata/16/88. 5'-O-p-Anisoylthymidine activates viral transcription in cells infected with these viruses by inhibiting the synthesis of deoxyribonucleosides. It also inhibits DNA synthesis by inhibiting the incorporation of deoxyribonucleotides into DNA during replication. This product is CAS No. 138581-03-2 and comes in high purity and high quality.</p>
    Fórmula:C18H20N2O7
    Pureza:Min. 95%
    Peso molecular:376.36 g/mol

    Ref: 3D-NA08693

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  • 2'-Deoxy-5-methyl-isocytidine triphosphate


    <p>2'-Deoxy-5-methyl-isocytidine triphosphate (2'-DMI-dTP) is a novel nucleoside that is synthesized by phosphoramidite chemistry. 2'-DMI-dTP has antiviral and anticancer activities, and can be used for the treatment of hepatitis B virus (HBV) and human papillomavirus (HPV). It has shown protective effects in animal models of HBV infection. 2'-DMI-dTP inhibits HBV replication by inhibiting DNA synthesis. In addition, it decreases levels of reactive oxygen species in cells treated with HBV. 2'-DMI-dTP also inhibits HPV replication through inhibition of DNA synthesis, which may lead to cancer prevention or treatment.<br>2'-DMI-dTP may be a useful drug candidate for the treatment of other viral infections such as influenza A virus and HIV type 1.</p>
    Pureza:Min. 95%

    Ref: 3D-ND76410

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  • S-(5'-Adenosyl)-L-homocysteine dihydrate

    CAS:
    <p>S-(5'-Adenosyl)-L-homocysteine dihydrate is the active form of homocysteine. It has been shown to inhibit the growth of HL-60 cells and induce apoptosis in these cells. S-(5'-Adenosyl)-L-homocysteine dihydrate binds to dsDNA as a methyltransferase inhibitor, which leads to DNA methylation and inhibits DNA binding. The inhibition of DNA binding prevents transcription, leading to cell death. This drug has also been shown to have an anti-atherosclerotic effect in a model system by inhibiting the adenosine receptor.</p>
    Fórmula:C14H20N6O5S•(H2O)2
    Pureza:Min. 98 Area-%
    Cor e Forma:Powder
    Peso molecular:420.44 g/mol

    Ref: 3D-NA17223

    25mg
    254,00€
    50mg
    401,00€
    100mg
    637,00€
    250mg
    1.174,00€
    500mg
    2.141,00€
  • 5'-Deoxy-5'-(methylthio)adenosine

    CAS:
    <p>5'-Deoxy-5'-(methylthio)adenosine is a nucleoside that has been shown to inhibit the growth of bowel cancer cells. 5'-Deoxy-5'-(methylthio)adenosine blocks the synthesis of DNA and RNA by inhibiting the action of enzymes involved in DNA metabolism. It also inhibits methionine synthase and phosphorylase, which are involved in protein synthesis. This compound has been shown to be effective in treating cancer tissues due to its ability to inhibit polymerase chain reactions and prevent the formation of cancerous cells.</p>
    Fórmula:C11H15N5O3S
    Pureza:(Hplc-Ms) Min. 98 Area-%
    Cor e Forma:White Powder
    Peso molecular:297.34 g/mol

    Ref: 3D-ND07992

    1g
    1.216,00€
    50mg
    193,00€
    100mg
    305,00€
    250mg
    511,00€
    500mg
    866,00€
  • Queuine hydrochloride

    CAS:
    <p>Queuine is a modified nucleoside found in tRNA. It is synthesized from guanosine by the enzyme queuine tRNA-ribosyltransferase, which converts guanosine to queuosine. Queuine hydrochloride is a synthetic form of queuine that can be used for research purposes to examine the anticodon loop and other structural features of the molecule. The prokaryotic and eukaryotic organisms studied showed different levels of synthesis of queuine, with bacteria synthesizing more than mammals. Bacteria were found to have a greater affinity for queuine than eukaryotes, which may be due to modification of the trna anticodon loop or to differences in ribosomal proteins.</p>
    Fórmula:C12H15N5O3·HCl
    Pureza:(%) Min. 90%
    Cor e Forma:Light (Or Pale) Beige To Light (Or Pale) Purple Solid
    Peso molecular:313.74 g/mol

    Ref: 3D-NQ177252

    1mg
    924,00€
    5mg
    3.507,00€
    500µg
    526,00€
  • 3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine


    <p>3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine is a modified nucleoside that is synthesized by the phosphoramidite method. It is a novel antiviral drug with anticancer properties. This active compound has been shown to be an activator of ribonucleotide reductases, which are enzymes that catalyze the conversion of ribonucleotides to deoxyribonucleotides. 3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine is not cytotoxic at concentrations up to 40 mM, and it has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV) in tissue culture.</p>
    Pureza:Min. 95%

    Ref: 3D-NA144642

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  • 5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine

    CAS:
    <p>5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine is a monophosphate antiviral agent. It has been shown to inhibit the activity of DNA and RNA polymerases in vitro. The drug is novel, and its antiviral properties have not been tested in vivo. 5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine has been synthesized using phosphoramidites and was found to be of high quality and purity. It has also been modified at the 2' position with an acetyl group and at the 3' position with a levulinoyl group.</p>
    Pureza:Min. 95%

    Ref: 3D-ND163002

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  • 5’(R)-C-Methyladenosine

    CAS:
    <p>5’(R)-C-Methyladenosine is a nucleoside that is used as an antiviral and anticancer agent. It has been shown to inhibit the replication of the human immunodeficiency virus type 1 (HIV-1) in a dose-dependent manner, with an IC50 value of about 0.4 μM for HIV-1 reverse transcriptase activity. In addition, 5’(R)-C-Methyladenosine has been shown to inhibit DNA synthesis and promote apoptosis in cancer cells by inhibiting transcription and translation. The compound also inhibits the growth of tumor cells in mice without affecting normal tissue growth.</p>
    Pureza:Min. 95%

    Ref: 3D-NM162919

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  • 1,5-Anhydro-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol


    <p>1,5-Anhydro-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol is a novel modified nucleoside that is used as an activator in the synthesis of oligodeoxynucleotides and ribonucleosides. It is also used for the synthesis of phosphoramidites for DNA and RNA molecules. This product is available in high purity and quality.</p>
    Fórmula:C18H19N5O4
    Pureza:Min. 95%
    Peso molecular:369.38 g/mol

    Ref: 3D-NA07922

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  • N6-Carbamoylthreonyladenosine sodium salt

    CAS:
    <p>N6-Carbamoylthreonyladenosine sodium salt is a fatty acid that is found in the bacterial cell wall. It has been shown to be an essential component of the cell wall for Gram-positive and Gram-negative bacteria. N6-Carbamoylthreonyladenosine sodium salt has been used to study the mechanism of protein synthesis in bacteria, especially how enzymes are involved in this process. Chemical biology studies have shown that this molecule can bind to DNA and inhibit bacterial growth. The crystal structure of N6-Carbamoylthreonyladenosine sodium salt has also been determined using x-ray diffraction data. This molecule inhibits the binding of proteins to DNA, which prevents transcription and replication. The reaction mechanism involves hydrogen bonding between the oxygen atoms on N6-Carbamoylthreonyladenosine sodium salt and divalent metal ions such as magnesium or zinc, which are required for protein synthesis.</p>
    Fórmula:C15H19N6O8·Na
    Pureza:Min. 98 Area-%
    Cor e Forma:White Powder
    Peso molecular:434.34 g/mol

    Ref: 3D-NC06332

    2mg
    386,00€
    5mg
    660,00€
    10mg
    1.008,00€
    25mg
    2.243,00€
    50mg
    4.074,00€
  • 1-(2R,3R,4R,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxytetra hydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione


    <p>1-(2R,3R,4R,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxytetra hydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione is a nucleoside that is a novel anticancer drug. It has been shown to have potent antineoplastic activity in vitro and in vivo. This compound is an activator of the p53 tumor suppressor gene and may also act as a transcriptional inhibitor of NF-κB.</p>
    Pureza:Min. 95%

    Ref: 3D-NH137506

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  • 3-Deaza-2'-O-methyluridine

    CAS:
    <p>3-Deaza-2'-O-methyluridine is a nucleoside that is used as an antiviral agent and in the treatment of leukemia. It has been shown to inhibit the growth of L1210 cells in a dose-dependent manner. 3-Deaza-2'-O-methyluridine also inhibits the synthesis of DNA, RNA, and proteins. The compound is eliminated by renal excretion with a plasma elimination half life of 9 hours. This drug can be administered intramuscularly or intravenously at a dosage of 10 mg/kg every 8 hours, but should not be given more than 5 days without interruption due to accumulation in tissues.</p>
    Fórmula:C11H15NO6
    Pureza:Min. 95%
    Peso molecular:257.24 g/mol

    Ref: 3D-ND58308

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  • Adenosine 3',5'-bisphosphate triethylammonium salt - 10mM aqueous solution

    CAS:
    <p>Adenosine 3',5'-bisphosphate triethylammonium salt is a metabolite of adenosine and an ester of triethylamine. The conjugate acid has been isolated from mouse urine. It is a metabolite of adenosine in the liver and is hydrolyzed to adenosine monophosphate and bisphosphate. Adenosine 3',5'-bisphosphate triethylammonium salt is used to study the metabolism of adenosine in mice. It has also been shown that this metabolite can inhibit the growth of E. coli (a bacterium) and mouse erythrocyte mitochondria by blocking ATP synthesis at the level of substrate-level phosphorylation.</p>
    Fórmula:C10H15N5O10P2•(C6H15N)x
    Pureza:Min. 95%
    Peso molecular:427.2 g/mol

    Ref: 3D-NA44795

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  • N4-Acetyl-3'-deoxy-3'-C-methylcytidine


    <p>N4-Acetyl-3'-deoxy-3'-C-methylcytidine is a novel antiviral drug that is modified from cytidine. It is an activator of the monophosphate pathway of DNA synthesis, which causes the incorporation of N4-acetyl-3'-deoxy-3'-C-methylcytidine into ribonucleosides and deoxyribonucleosides. This compound has been shown to be active against a variety of cancers, including leukemia, colon cancer, breast cancer, and prostate cancer.</p>
    Fórmula:C12H17N3O5
    Pureza:Min. 95%
    Peso molecular:283.28 g/mol

    Ref: 3D-NA15623

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  • 3-Acetylpyridine adenine dinucleotide

    CAS:
    <p>A non-physiological analog of nicotinamide adenine dinucleotide (NAD+) in biochemical research, particularly as a tool to study the mechanisms of NAD+-dependent enzymes.</p>
    Fórmula:C22H28N6O14P2
    Pureza:Min. 92 Area-%
    Cor e Forma:White Off-White Powder
    Peso molecular:662.44 g/mol

    Ref: 3D-NA30683

    1g
    778,00€
    2g
    973,00€
    100mg
    246,00€
    250mg
    369,00€
    500mg
    513,00€
  • 2',3'-Dideoxyguanosine

    CAS:
    <p>2',3'-Dideoxyguanosine is a nucleoside for use in research applications</p>
    Fórmula:C10H13N5O3
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:251.25 g/mol

    Ref: 3D-ND04069

    1g
    1.078,00€
    2g
    1.643,00€
    100mg
    282,00€
    250mg
    472,00€
    500mg
    717,00€
  • Fluorescein-5(6)-carboxamidocaproyl-[5(3-aminoallyl)2-deoxyuridine-5-tr


    <p>Fluorescein-5(6)-carboxamidocaproyl-[5(3-aminoallyl)2-deoxyuridine-5-triphosphate] is a modified nucleoside analog that is used as an antiviral agent against herpesviruses. This compound is phosphorylated by the virus encoded thymidine kinase, which converts it to the monophosphate form. Fluorescein-5(6)-carboxamidocaproyl-[5(3-aminoallyl)2-deoxyuridine-5-triphosphate] inhibits DNA synthesis by inhibiting viral DNA polymerase and has been shown to be active against human papillomavirus type 16 (HPV16) in vitro. It has also been shown to inhibit tumor cell proliferation and induce apoptosis in some types of cancer cells.</p>
    Pureza:Min. 95%

    Ref: 3D-NF11636

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  • 3'-O-Propargylcytidine


    <p>3'-O-Propargylcytidine is a monophosphate nucleoside that belongs to the group of synthetic, novel nucleosides and deoxyribonucleosides. It is a modified form of cytidine with an extra methyl group attached to the 3' position of the ribose sugar. 3'-O-Propargylcytidine has been shown to inhibit cancer cells by binding to DNA and preventing transcription and replication. This compound also inhibits virus replication and has antiviral properties. 3'-O-Propargylcytidine is highly pure and high quality, which makes it a good candidate for use in pharmaceuticals or other applications requiring high purity.</p>
    Fórmula:C12H15N3O5
    Pureza:(%) Min. 97%
    Cor e Forma:Powder
    Peso molecular:281.26 g/mol

    Ref: 3D-NP06049

    25mg
    305,00€
    50mg
    502,00€
    100mg
    716,00€
  • O6-Methylguanosine

    CAS:
    <p>Intermediate in the synthesis of nelarabine</p>
    Fórmula:C11H15N5O5
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:297.27 g/mol

    Ref: 3D-NM02922

    2g
    229,00€
    5g
    403,00€
    10g
    598,00€
    25g
    1.067,00€
    50g
    1.600,00€
  • [2'-18O]Guanosine


    <p>[2'-18O]Guanosine is a novel antiviral that has shown antiviral activity against herpes simplex virus type 1 and cytomegalovirus. It also has anticancer effects, as it inhibits the growth of lymphoma cells by inhibiting DNA synthesis. [2'-18O]Guanosine is a modified nucleotide with an 18-oxygen atom in the 2' position, which prevents its use as a substrate for phosphodiesterases, thereby increasing its stability in vivo. [2'-18O]Guanosine is synthesized from the corresponding ribonucleotide, guanosine monophosphate (GMP), and can be used as an activator for DNA synthesis and an inhibitor of RNA synthesis.</p>
    Fórmula:C10H13N518OO4
    Pureza:Min. 95%
    Peso molecular:285.24 g/mol

    Ref: 3D-NG106386

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  • 2'-Deoxy-5'-O-DMT-2'-fluorouridine

    CAS:
    <p>2'-Deoxy-5'-O-DMT-2'-fluorouridine is a medicament that belongs to the group of antineoplastic agents and is used in cancer treatment. It inhibits the synthesis of DNA by inhibiting the enzyme thymidylate synthetase, which is required for the formation of thymine nucleotides. This drug has been shown to be effective against some cancer cells in vitro and in vivo, but not all. 2'-Deoxy-5'-O-DMT-2'-fluorouridine can also inhibit terminal growth phases and induce programmed cell death. Solid phase synthesis has been used to synthesize this molecule as a phosphoramidite.</p>
    Fórmula:C30H29FN2O7
    Pureza:Min. 98 Area-%
    Cor e Forma:White Powder
    Peso molecular:548.57 g/mol

    Ref: 3D-ND06064

    5g
    228,00€
    10g
    420,00€
    25g
    860,00€
    50g
    1.591,00€
    100g
    2.213,00€
  • 5-(N-Isopentenyl-N-trifluoroacetyl)aminomethyluridine

    CAS:
    <p>5-(N-Isopentenyl-N-trifluoroacetyl)aminomethyluridine is a nucleoside analog that is structurally related to cytidine. It was first synthesized in the 1970s, and has been shown to possess antiviral activity against herpes simplex virus type 1. In addition, it has been shown to inhibit DNA synthesis and the formation of DNA double strands. 5-(N-Isopentenyl-N-trifluoroacetyl)aminomethyluridine is an activator of protein kinase C and cyclic AMP phosphodiesterase, as well as a DNA polymerase inhibitor with anticancer properties.</p>
    Pureza:Min. 95%

    Ref: 3D-NI162860

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  • 2-Iodoadenosine

    CAS:
    <p>2-Iodoadenosine is a chemical compound that is produced from the oxidation of uridine. It is used in the synthesis of peptides, which are important for biological processes like signal transduction and cell growth. 2-Iodoadenosine can be made by coupling other molecules to an adenosine molecule. This process involves a cross-coupling reaction with palladium catalysts or hydroxylation reactions with sodium borohydride. The resulting product has been shown to have anticancer and anti-microbial activities against protozoan parasites and cyclic peptide structures.</p>
    Fórmula:C10H12IN5O4
    Pureza:Min. 97 Area-%
    Cor e Forma:Powder
    Peso molecular:393.14 g/mol

    Ref: 3D-NI04749

    1g
    430,00€
    2g
    598,00€
    5g
    962,00€
    10g
    1.494,00€
    500mg
    250,00€
  • 2'-Azido-2'-deoxyadenosine

    CAS:
    <p>2'-Azido-2'-deoxyadenosine is a synthetic nucleoside analog of adenosine in which the 2'-hydroxyl group of the ribose sugar is replaced by an azido group (–N₃), and the 3'- and 5'-hydroxyl groups remain intact. This modification confers unique chemical properties, including the ability to participate in bioorthogonal "click" chemistry reactions, particularly azide-alkyne cycloadditions, making it useful for labeling and tracking nucleic acids in biochemical studies. Additionally, the azido substitution can influence enzymatic recognition and incorporation by polymerases, allowing its use in studying nucleic acid metabolism, drug design, and therapeutic nucleoside analog development.</p>
    Fórmula:C10H12N8O3
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:292.25 g/mol

    Ref: 3D-NA02932

    25mg
    341,00€
    50mg
    486,00€
    100mg
    729,00€
    250mg
    1.086,00€
    500mg
    1.952,00€
  • 2’-Deoxy-2’-fluoroadenosine 5’-monophosphate triethyl ammonium salt


    <p>2’-Deoxy-2’-fluoroadenosine 5’-monophosphate triethyl ammonium salt is a nucleoside phosphoramidite that acts as an antiviral agent. It is used to treat influenza and herpes simplex virus infections. 2’-Deoxy-2’-fluoroadenosine 5’-monophosphate triethyl ammonium salt also inhibits the growth of cancer cells, but has not been shown to be effective against bacterial or fungal infections.</p>
    Pureza:Min. 95%

    Ref: 3D-ND163172

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  • 2'-Deoxyadenosine-5'-monophosphate disodium salt

    CAS:
    <p>2'-Deoxyadenosine-5'-monophosphate disodium salt (DAP) is a white crystalline powder. It is soluble in water and insoluble in ethanol. DAP can be neutralised by aqueous solutions of hydroxide, such as sodium hydroxide or ammonium hydroxide. DAP is also reactive with aluminium oxide, which can be used for drying the compound to form anhydrous particles. DAP reacts with chloride ions to form 2',3'-diacetylpyridine-5'-diphosphate dibasic chloride, which has been shown to inhibit bacterial growth and act as an antibacterial agent. Autoclaving may be required for preparation of this drug due to its sensitivity to heat energy.</p>
    Fórmula:C10H12N5Na2O6P
    Pureza:Min. 99 Area-%
    Cor e Forma:White Powder
    Peso molecular:375.19 g/mol

    Ref: 3D-ND15298

    1g
    200,00€
    2g
    349,00€
    5g
    598,00€
    10g
    906,00€
  • 2'-Deoxy-6-thioguanosine-5'-monophosphate

    CAS:
    <p>Azathioprine is a drug that suppresses the immune system and is used to treat autoimmune disorders such as rheumatoid arthritis, lupus erythematosus, and inflammatory bowel disease. It is an immunosuppressant that prevents the formation of antibodies by blocking the enzyme thiopurine S-methyltransferase. Azathioprine is metabolized in the liver to 6-mercaptopurine, which has been shown to cause leukopenia. The genetic polymorphism of this enzyme can lead to differences in the metabolism and toxicity of azathioprine therapy.</p>
    Fórmula:C10H14N5O6PS
    Pureza:Min. 95%
    Peso molecular:363.29 g/mol

    Ref: 3D-ND159697

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  • 4-Amino-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-5-carboxamide

    CAS:
    <p>4-Amino-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-5-carboxamide is a synthetic compound that inhibits protein synthesis by binding to the 50S ribosomal subunit. It also prevents viral replication by inhibiting the incorporation of amino acids into proteins. 4-Amino-7-(2-deoxy-b-Dribofuranosyl)-7H pyrrolo[2,3 d]pyrimidin 5 carboxamide binds to the 50S ribosomal subunit and blocks tRNA entry into the A site of the ribosome. This binding prevents translation and transcription of mRNA, effectively inhibiting protein synthesis. It has been shown to be effective against murine leukemia virus (MLV), influenza A virus, and herpes simplex virus type 1 (HSV1) in cell culture</p>
    Fórmula:C12H15N5O4
    Pureza:Min. 95%
    Peso molecular:293.28 g/mol

    Ref: 3D-NA144685

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  • Adenosine 5'-phosphosulfate sodium salt, 10 mM in water

    CAS:
    <p>Adenosine 5′-phosphosulfate sodium salt has been used quantify pyrophosphate and in enzyme-linked bioluminescence assay for adenosine triphosphate (ATP).Product provided as 10 mM solution in water.</p>
    Fórmula:C10H14N5O10PS
    Pureza:Min. 90.0 Area-%
    Peso molecular:427.28 g/mol

    Ref: 3D-NA159234

    10mg
    140,00€
    25mg
    141,00€
    50mg
    191,00€
    100mg
    303,00€
    250mg
    504,00€
  • 5-Fluorouridine

    CAS:
    <p>5-Fluorouridine, also called 1-(b-D-ribofuranosyl)-5-fluorouracil and 5-fluoro-D-uridine (FUrd), is a modified uridine nucleoside with a fluorine atom at position 5 of the uracil. 5-Fluorouridine is a highly cytotoxic metabolite of 5-fluorouracil, a drug used to treat a variety of cancers, on the market with the trade name Adrucil. Prodrugs of 5-fluorouridine have been investigated for anti-tumour properties in their own right and are close structural analogues of 5'-deoxy-5-fluorouridine, a cytostatic agent in chemotherapy.</p>
    Fórmula:C9H11FN2O6
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:262.2 g/mol

    Ref: 3D-NF04076

    10g
    280,00€
    25g
    472,00€
    50g
    701,00€
    100g
    1.085,00€
  • 5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine

    CAS:
    <p>5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine is a nucleoside analog. It is synthesized by substituting the hydroxyl group of uridine with a fluorine atom and the 2' position of ribose with a 5'-O-acetyl group. This modification prevents the incorporation of this nucleoside into DNA or RNA, making it an effective antiviral and anticancer agent. 5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine has been shown to be highly active against tumor cells but not normal cells in vitro.</p>
    Fórmula:C11H11N2O5
    Pureza:Min. 95%
    Peso molecular:251.22 g/mol

    Ref: 3D-NA144872

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  • 5-o-(Dimethoxytrityl)-N4-dimethylaminomethylidene-5-iodo-2'-deoxycytidine

    CAS:
    <p>Dimethoxytrityl-5-iodo-2'-deoxycytidine is a novel, modified nucleoside that has anticancer and antiviral properties. It is synthesized by reacting 5-iodo-2'-deoxycytidine with dimethoxytrityl chloride in the presence of triethylamine. This compound can be used to synthesize oligonucleotide phosphoramidites, ribonucleosides, and diphosphates.</p>
    Fórmula:C33H35IN4O6
    Pureza:Min. 95%
    Peso molecular:710.6 g/mol

    Ref: 3D-SDB87696

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  • 5'-O-p-Anisoyl-3'-fluoro-2',3'-dideoxyuridine


    <p>5'-O-p-Anisoyl-3'-fluoro-2',3'-dideoxyuridine (5-FAU) is a deoxynucleoside that is synthesized by the phosphoramidite method, and it has been used as an antiviral agent. 5-FAU is a novel nucleoside analog with anticancer activity. It inhibits replication of herpes simplex virus type 1 and 2, varicella zoster virus, and Epstein Barr virus in cell culture. 5-FAU also inhibits HIV replication in vitro and in animal models. The antiviral activity of 5-FAU is due to its inhibition of viral DNA polymerase, which prevents the synthesis of viral DNA from viral RNA templates.</p>
    Fórmula:C17H17FN2O6
    Pureza:Min. 95%
    Peso molecular:364.33 g/mol

    Ref: 3D-NA08202

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  • 4’,5’-Didehydro-2’-O-(2-methoxyethyl)uridine

    CAS:
    <p>4’,5’-Didehydro-2’-O-(2-methoxyethyl)uridine (4,5DDMU) is a novel nucleoside analog that is phosphorylated to 4,5-didehydro-2'-O-(2-methoxyethyl)uridine 5'-triphosphate. This nucleoside has been shown to inhibit the proliferation of human cancer cells in vitro and in vivo. 4,5DDMU inhibits viral replication by generating diphosphate derivatives of the viral DNA polymerase enzyme that are unable to synthesize DNA. 4,5DDMU also inhibits HIV replication by inhibiting reverse transcriptase activity in the virus.End&gt;</p>
    Pureza:Min. 95%

    Ref: 3D-ND163042

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  • N4-Benzoyl-3'-O-tert-butydimethylsilylcytidine 2'-CE-phosphoramidite


    <p>N4-Benzoyl-3'-O-tert-butydimethylsilylcytidine 2'-CE-phosphoramidite is a novel nucleoside analog that has shown anticancer and antiviral activity. It is a monophosphate, modified nucleoside that inhibits the deoxyribonucleotide biosynthetic pathway in cells. N4-Benzoyl-3'-O-tert-butydimethylsilylcytidine 2'-CE-phosphoramidite can be used as an activator of ribonuclease S1 and ribonuclease T1, which are enzymes involved in the process of DNA replication. In addition to its use as a therapeutic agent, this compound is also used for research purposes.</p>
    Fórmula:C52H66N5O9PSi
    Pureza:Min. 95%
    Peso molecular:964.17 g/mol

    Ref: 3D-PT57504

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  • 4-7H-Chloro-5-iodo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine

    CAS:
    <p>4-7H-Chloro-5-iodo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine is a modified nucleoside that has been shown to have antiviral, anticancer and activator properties. This compound is synthesized by the reaction of 4,7H chloro 5 Iodo 7 (2 C methyl b D ribofuranosyl) 7 H pyrrolo[2,3 d]pyrimidine with 2 C methyl b D ribofuranosyl in aqueous solution at neutral pH. 4 - 7 H Chloro 5 Iodo 7 (2 C methyl b D ribofuranosyl) 7 H pyrrolo [2,3 d] pyrimidine reacts with 2 C methyl b D ribofuranosyl to form 4 - 7 H Chlor</p>
    Pureza:Min. 95%

    Ref: 3D-NC14083

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  • Inosine-3',5'-cyclic-monophosphate triethylammonium - 10 mM aqueous solution


    <p>Inosine-3',5'-cyclic-monophosphate triethylammonium is a synthetic nucleoside that functions as an activator of the deoxyribonucleotide synthesis. It has antiviral and anticancer properties, and has been shown to have anti-inflammatory activities. Inosine-3',5'-cyclic-monophosphate triethylammonium has been shown to inhibit the growth of cells in culture and induce apoptosis. This is due to its ability to inhibit DNA synthesis by inhibiting the enzyme ribonucleotide reductase.</p>
    Fórmula:C10H11N4O7P·NC6H15
    Pureza:Min. 95%
    Peso molecular:431.38 g/mol

    Ref: 3D-NI170530

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  • N′-[9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-6,9-dihydro-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide

    CAS:
    <p>Please enquire for more information about N′-[9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-6,9-dihydro-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C13H17FN6O4
    Pureza:Min. 95%
    Peso molecular:340.31 g/mol

    Ref: 3D-NF183584

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  • 2,4-Dithiothymidine

    CAS:
    <p>2,4-Dithiothymidine (DT) is a chemotherapeutic that has been shown to be clinically effective in the treatment of hematopoietic malignancies. It is an oligothymidylate analogue that contains a pyrimidine heterocycle and an ethylthio group. DT is not a nucleoside analog, but it inhibits DNA synthesis by binding to the enzyme thymidylate synthase and preventing the formation of thymine from uracil. DT also binds to single-stranded DNA with high affinity and alters its conformation, which may inhibit transcription and replication. The photophysical properties of this molecule are studied theoretically using quantum mechanics and population analysis theory. The reagent DT can be used to focus attention on other molecules or conformation states of proteins that might have improved biological activity.</p>
    Fórmula:C10H14N2O3S2
    Pureza:Min. 95%
    Peso molecular:274.36 g/mol

    Ref: 3D-ND165186

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  • 5-Aza-N6-benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite

    CAS:
    <p>5-Aza-N6-benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite is a monophosphate, Synthetic, DNA Activator, Anticancer, Modified, Novel, Nucleosides. It has the CAS No. 929904-98-3 and is High purity.</p>
    Fórmula:C46H53N6O9P
    Pureza:Min. 95%
    Peso molecular:864.92 g/mol

    Ref: 3D-PA145468

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  • N6-Succinyl adenosine

    CAS:
    <p>N6-Succinyl adenosine is a biochemical that is involved in the transfer of fatty acids across membranes. It has been shown to be effective in transfection experiments, where it can be used to increase the expression of genes. N6-Succinyl adenosine has also been shown to be an important substrate for various dehydrogenases. Deficiency of these enzymes leads to orotic aciduria, which is characterized by elevated levels of orotic acid in blood and urine and may lead to mental retardation. A linear calibration curve was generated for diagnosis purposes, with the enzyme activities being determined using a logistic regression model.</p>
    Fórmula:C14H17N5O8
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:383.31 g/mol

    Ref: 3D-NS16562

    1mg
    496,00€
    2mg
    706,00€
    5mg
    1.135,00€
    10mg
    1.995,00€
    25mg
    3.300,00€
  • 2'-C-Methyladenosine 5'-triphosphate triethyl ammonium salt - Aqueous solution

    CAS:
    <p>2'-C-Methyladenosine 5'-triphosphate triethyl ammonium salt is a synthetic nucleotide analog of adenosine triphosphate (ATP), modified at the 2'-carbon of the ribose ring. This molecule has potential applications in biochemical, enzymatic, and antiviral research, particularly in studies involving RNA synthesis and viral RNA polymerases.</p>
    Fórmula:C35H79N9O13P3
    Pureza:Min. 95%
    Cor e Forma:Colorless Powder
    Peso molecular:926.98 g/mol

    Ref: 3D-NM29122

    5mg
    1.061,00€
    10mg
    1.516,00€
    25mg
    3.321,00€
    50mg
    5.166,00€
  • 2'(3')-O-(4-Benzoyl)benzoyladenosine-5'-triphosphate triethylammonium salt

    CAS:
    <p>2'(3')-O-(4-Benzoyl)benzoyladenosine-5'-triphosphate triethylammonium salt is a nucleoside analog of Adenosine-5'-triphosphate (ATP), a key player in cellular energy transfer. 2'(3')-O-(4-Benzoyl)benzoyl has been added to this molecule as well as a triethylammonium salt which helps to increase the stability of the molecule in solutions. 2'(3')-O-(4-Benzoyl)benzoyladenosine-5'-triphosphate triethylammonium salt has potential use as a tool for understanding how cells use ATP and how changes to ATP affect cellular processes. Other possible uses are in the study of how ATP interacts with enzymes.</p>
    Fórmula:C24H24N5O15P3·C6H15N
    Pureza:Min. 75 Area-%
    Cor e Forma:White Powder
    Peso molecular:816.58 g/mol

    Ref: 3D-NB29594

    5mg
    301,00€
    10mg
    389,00€
    25mg
    534,00€
    50mg
    928,00€
    100mg
    1.646,00€
  • 4-Thiothymidine

    CAS:
    <p>4-Thiothymidine is a nucleoside analog that is converted to thymidine by the enzyme thymidine kinase. It has been shown to inhibit the growth of human skin cancer cells by binding to DNA duplexes and inhibiting the synthesis of new DNA strands. 4-Thiothymidine has also been shown to be effective against radiation-induced damage in cultured human cells and inhibits tumor growth in mice bearing a transplantable mouse skin cancer. 4-Thiothymidine can be used as an inhibitor for chemotherapy or radiation therapy for cancer patients. It is active on both site-specific and cell-specific gene targets, with a reactive hydrogen bond that helps stabilize its formation.</p>
    Fórmula:C10H14N2O4S
    Pureza:Min. 98 Area-%
    Cor e Forma:Yellow Powder
    Peso molecular:258.3 g/mol

    Ref: 3D-NT06341

    1g
    747,00€
    2g
    1.259,00€
    5g
    2.650,00€
    250mg
    400,00€
    500mg
    532,00€
  • N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-O-succinate triethylammonium salt

    CAS:
    <p>N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-O-succinate triethylammonium salt is a novel nucleoside analog that has antiviral and anticancer properties. It is a ribonucleotide with an N6-(benzoyl)-2'-deoxyadenosine base linked to the 3' position of the sugar through an acetyl group, with a succinic acid moiety at the 5' position. This drug inhibits DNA synthesis and has been shown to block HIV replication in vitro. It also has activity against human papillomavirus type 16 (HPV16) infections in vivo.</p>
    Fórmula:C42H39N5O9·C6H15N
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:858.98 g/mol

    Ref: 3D-NB10413

    2g
    337,00€
    3g
    464,00€
    5g
    662,00€
    10g
    1.117,00€
  • 5-Methoxy-2-thiouridine

    CAS:
    <p>5-Methoxy-2-thiouridine is the peracylated form of thiouracil. It is a reactive oxygen species, which can cause primary site lesions in cells. 5-Methoxy-2-thiouridine is a posttranscriptional modification that leads to conformational changes in the anticodon loop of tRNA molecules. This modification prevents the anticodon from pairing with its corresponding codon during translation, thereby inhibiting protein synthesis. The modifications also affect RNA processing and stability and lead to changes in gene expression.</p>
    Pureza:Min. 95%

    Ref: 3D-FM162894

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  • 7-Deaza-2'-deoxyguanosine

    CAS:
    <p>7-Deaza-2'-deoxyguanosine is an analog of guanosine that has been shown to inhibit the activity of telomerase. This enzyme synthesizes a sequence of DNA called a telomere, which protects the ends of chromosomes from deterioration and prevents chromosomal end-to-end fusion. 7-Deaza-2'-deoxyguanosine has an inhibitory effect on the polymerase chain reaction (PCR) in mammalian cells and inhibits the transcription-polymerase chain reaction (PCR) in vitro. It has also been shown to be potent against cancer cells. 7-Deaza-2'-deoxyguanosine is synthesized by solid phase synthesis, which is a chemical process that involves attaching one molecule to another molecule with similar structure, using organic solvents as intermediates.</p>
    Fórmula:C11H14N4O4
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:266.26 g/mol

    Ref: 3D-ND02887

    1g
    1.675,00€
    50mg
    223,00€
    100mg
    363,00€
    250mg
    681,00€
    500mg
    1.024,00€
  • 2'-O-Allylcytidine

    CAS:
    <p>2'-O-Allylcytidine is a synthetic nucleotide that contains an allylated amino function. It is synthesized by the regiospecific allylation of uridine and guanosine. 2'-O-Allylcytidine has been used in research studies for the synthesis of oligonucleotides with specific sequences and for high-yield production of synthons.</p>
    Fórmula:C12H17N3O5
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:283.28 g/mol

    Ref: 3D-NA06245

    10mg
    135,00€
    25mg
    178,00€
    50mg
    255,00€
  • 5'-O-p-Anisoyl-2'-O-tert-butyldimethylsilyl-5-methyluridine 3'-CE phosphoramidite


    <p>5'-O-p-Anisoyl-2'-O-tert-butyldimethylsilyl-5-methyluridine 3'-CE phosphoramidite is an activator of DNA synthesis. It is a novel and modified monophosphate that has been designed for the synthesis of DNA, RNA and other nucleosides. 5'-O-p-Anisoyl-2'-O-tert butyldimethylsilyl-5-methyluridine 3'-CE phosphoramidite has antiviral and anticancer properties. It can be used in the synthesis of oligonucleotides, which are short chains of nucleotides used as probes or drugs to inhibit gene expression. 5'-O-p-Anisoyl 2'-O tert butyldimethylsilyl 5 methyluridine 3' CE phosphoramidite is a high purity compound with CAS number 129225 -</p>
    Fórmula:C33H51N4O9PSi
    Pureza:Min. 95%
    Peso molecular:706.84 g/mol

    Ref: 3D-PA08686

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  • 4'-Thiothymidine

    CAS:
    <p>4'-Thiothymidine is a nucleoside analog that is used in antiviral therapy against herpes simplex virus. It inhibits the viral DNA polymerase, which prevents the virus from duplicating its genetic material. 4'-Thiothymidine has been shown to inhibit the uptake of 4-thiouracil by cells and to have anti-inflammatory properties. The drug has been found to be effective in inhibiting human adenocarcinoma cell lines in vitro and in vivo.</p>
    Fórmula:C10H14N2O4S
    Pureza:Min. 95%
    Peso molecular:258.30 g/mol

    Ref: 3D-NT57661

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