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Nucleosídeos

Nucleosídeos

Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.

Foram encontrados 3567 produtos de "Nucleosídeos"

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  • 5'-O-DMT-2,3'-anhydrothymidine

    CAS:
    <p>5'-O-DMT-2,3'-anhydrothymidine is a solvent that is used for labeling nucleic acids. It can be used in positron emission tomography (PET) imaging as a diagnostic tool for cancer and other diseases. 5'-O-DMT-2,3'-anhydrothymidine is also used to carry the radioactive isotope fluorodeoxyglucose (FDG) in positron emission tomography (PET). The FDG is labeled with the PET tracer and then injected into the patient's body. This allows for whole-body visualization of glucose metabolism and tumor cell uptake.</p>
    Fórmula:C31H30N2O6
    Pureza:Min. 95%
    Peso molecular:528.61 g/mol

    Ref: 3D-ND03508

    1g
    2.623,00€
  • 3’-Deoxy-3’C-methyladenosine

    CAS:
    <p>3’-Deoxy-3’C-methyladenosine is a reaction product of DNA and cancer cells. This product is generated by the glycosylase enzyme, which removes a methyl group from cytosine to produce 3’-deoxyadenosine. It has been shown that 3’-deoxy-3’C-methyladenosine accumulates in animal tissues after chronic treatment with an anticancer drug and can be detected using chromatographic methods. The presence of this compound in animals can be used as an indicator for carcinogenesis. 3’-Deoxy-3’C-methyladenosine has also been shown to inhibit the replication of mammalian cells.</p>
    Pureza:Min. 95%

    Ref: 3D-ND157123

    25mg
    2.288,00€
    50mg
    3.050,00€
  • N2-Isobutyryl-5’-O-DMT-morpholinoguanosine-N’-CE phosphoramidite

    CAS:
    <p>A morpholino amidite</p>
    Fórmula:C44H55N8O7P
    Pureza:Min. 98 Area-%
    Cor e Forma:Powder
    Peso molecular:838.93 g/mol

    Ref: 3D-NI184363

    1g
    1.013,00€
    100mg
    291,00€
    500mg
    742,00€
  • N6-Benzoyl-5’-O-DMT-morpholinoadenosine-N’-CE phosphoramidite

    CAS:
    <p>A morpholino amidite</p>
    Fórmula:C47H53N8O6P
    Pureza:Min. 98 Area-%
    Cor e Forma:Powder
    Peso molecular:856.95 g/mol

    Ref: 3D-NB184362

    1g
    978,00€
    100mg
    291,00€
    500mg
    729,00€
  • 7’-O-DMT-morpholino-5-methyluridine-N’-CE phosphoramidite

    CAS:
    <p>a morpholino amidite</p>
    Fórmula:C40H50N5O7P
    Pureza:Min. 98 Area-%
    Cor e Forma:Powder
    Peso molecular:743.83 g/mol

    Ref: 3D-ND184360

    1g
    978,00€
    100mg
    291,00€
    500mg
    729,00€
  • Thymidine-5'-diphosphate-2-deoxy-D-glucose disodium salt


    <p>Thymidine-5'-diphosphate-2-deoxy-D-glucose disodium salt is a novel, modified nucleoside that is chemically synthesized from 2,3,4,6-tetraaminopyrimidine. It has antiviral activity and can be used to treat HIV infections. It is an active form of thymidine and inhibits the synthesis of viral DNA by blocking the activity of viral DNA polymerase in reverse transcription. This drug also exhibits anticancer activity by preventing cell proliferation and inducing apoptosis. Thymidine-5'-diphosphate-2-deoxy-D-glucose disodium salt is high purity with a CAS number of 63625-04-9.</p>
    Fórmula:C16H24N2O15P2Na2
    Pureza:Min. 95%
    Peso molecular:592.29 g/mol

    Ref: 3D-NT29842

    50mg
    4.270,00€
  • Lauroyl coenzyme A

    CAS:
    <p>Lauroyl CoA is a body-fat molecule that can be formed from acetyl-coenzyme A, which is an intermediate in the metabolism of fatty acids. It is used in analysis as a standard for enzyme activities and as a substrate for reactions involving enzymes with coenzyme A. Reaction mechanisms are determined using titration calorimetry and structural analyses are performed using analytical methods such as infrared spectroscopy and nuclear magnetic resonance spectroscopy. Lauroyl CoA is also used to study the effects of the protein toll-like receptor 4 on hepatic steatosis. The wild-type strain of Escherichia coli was used to measure the activity of bacterial synthetases containing lauroyl CoA.</p>
    Fórmula:C33H58N7O17P3S
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:949.84 g/mol

    Ref: 3D-NL47197

    5mg
    A consultar
    10mg
    A consultar
    25mg
    A consultar
    50mg
    A consultar
    100mg
    A consultar
  • N6-Benzoyl-2’-O-tert-butyldimethylsilyl-3’-O-DMT-adenosine

    CAS:
    <p>N6-Benzoyl-2’-O-tert-butyldimethylsilyl-3’-O-DMT-adenosine is a novel nucleoside that is an activator of ribonucleotide reductase and an inhibitor of deoxyribonucleotide reductase. It has been shown to have antiviral and anticancer activities, as well as the ability to inhibit DNA synthesis. The synthetic route to this compound begins with the synthesis of N6-(benzoyl)-2'-O-(tert-butyldimethylsilyl)-3'-O-(dimethoxytrityl)adenosine, which is then converted to the final product by removal of the silyl protecting group and oxidation.</p>
    Pureza:Min. 95%

    Ref: 3D-NB163067

    1g
    478,00€
    2g
    770,00€
    5g
    1.547,00€
    500mg
    322,00€
  • 6-Methylthiopurine ribonucleotide

    CAS:
    <p>6-Methylthiopurine ribonucleotide is an inhibitor that belongs to the group of analogs of betamethasone. It has been shown to have anti-cancer properties and can induce apoptosis in cancer cells. This compound has also been studied for its potential use in treating urinary tract infections, as it has been shown to inhibit the growth of bacteria such as chlorhexidine-resistant strains. Additionally, 6-Methylthiopurine ribonucleotide has been found to be a potent inhibitor of human kinase and may have therapeutic potential for a variety of diseases. This compound has also been investigated as an inhibitor of tolvaptan, which is used to treat conditions such as hyponatremia. Overall, 6-Methylthiopurine ribonucleotide shows promising potential for the treatment of various diseases and conditions.</p>
    Fórmula:C11H15N4O7PS
    Pureza:Min. 95%
    Peso molecular:378.3 g/mol

    Ref: 3D-HAA02152

    5mg
    1.639,00€
    10mg
    2.554,00€
    25mg
    4.788,00€
    50mg
    7.661,00€
  • 5'-O-DMT-N2-isopropylphenoxyacetyl-2'-O-(2-methoxyethyl)guanosine 3'-O succinate TEA salt


    <p>5'-O-DMT-N2-isopropylphenoxyacetyl-2'-O-(2-methoxyethyl)guanosine 3'-O succinate TEA salt is a modified nucleoside with anticancer activity. It is a diphosphate that can be used for the synthesis of DNA and RNA. This product is synthesized by the reaction of 5'-O-dimethoxytritylthymidine (5'-DMTT), 2'-O-(2-methoxyethyl)hydroxylamine hydrochloride, and succinic anhydride in the presence of triethylamine. The product is purified by column chromatography, followed by recrystallization from hot acetonitrile. CAS No.: 102972-73-0</p>
    Fórmula:C49H52N5O13·C6H16N
    Pureza:Min. 95%
    Peso molecular:1,021.16 g/mol

    Ref: 3D-PD158846

    25mg
    303,00€
    50mg
    336,00€
  • 2',3',5'-Tris-O-[tert-butyldimethylsilyl]-2-chloroadenosine

    CAS:
    <p>2',3',5'-Tris-O-[tert-butyldimethylsilyl]-2-chloroadenosine is a phosphoramidite that can be used in the synthesis of ribonucleosides, deoxyribonucleosides, and nucleoside analogues. It is a novel compound that has antiviral and anticancer properties. This product is synthesized from 2,3,5-trichloropyrimidine by reaction with tert-butyldimethylsilyl chloride in the presence of triethylamine. The product is purified by vacuum distillation and characterized using proton nuclear magnetic resonance (NMR) spectroscopy.</p>
    Fórmula:C28H54ClN5O4Si3
    Pureza:Min. 95%
    Peso molecular:644.47 g/mol

    Ref: 3D-NT16652

    1g
    1.632,00€
    50mg
    303,00€
    100mg
    345,00€
    250mg
    559,00€
    500mg
    957,00€
  • 7-Deaza-2'-deoxy-5'-O-DMT-adenosine

    CAS:
    <p>7-Deaza-2'-deoxy-5'-O-DMT-adenosine is a nucleoside that has been synthesized by reacting 7-deaza-2'-deoxyadenosine with 5,6,7,8-tetrahydro-1H-[1]pyrazolo[3,4]pyrimidin-4(3H)-one. It is a novel anticancer agent that has been shown to inhibit the proliferation of various tumor cells in vitro. The cytotoxic effects of 7-deaza-2'-deoxy-5'-O-DMT adenosine are due to its ability to activate DNA synthesis while inhibiting DNA repair. It also inhibits ribonucleotide reductase and protein synthesis.</p>
    Fórmula:C32H32N4O5
    Pureza:Min. 95%
    Peso molecular:552.62 g/mol

    Ref: 3D-ND166812

    1g
    1.099,00€
    2g
    1.408,00€
    5g
    1.920,00€
    10g
    2.806,00€
    500mg
    860,00€
  • 8,5’(S)-Cycloguanosine

    CAS:
    <p>Please enquire for more information about 8,5’(S)-Cycloguanosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C10H10N5O5
    Pureza:Min. 95%

    Ref: 3D-NC06310

    1mg
    3.380,00€
  • 2'-Deoxy-2'-fluoroadenosine-5'-triphosphate sodium salt - 100mM aqueous solution


    <p>2'-Deoxy-2'-fluoroadenosine-5'-triphosphate sodium salt - 100mM aqueous solution is a high purity synthetic compound that is used as an activator for the synthesis of DNA, RNA, and phosphoramidites. The product is in the form of a white to off-white solid and has high quality with purity of &gt;99%. 2'-Deoxy-2'-fluoroadenosine-5'-triphosphate sodium salt - 100mM aqueous solution can be used in antiviral, anticancer, and antideoxyribonucleoside therapy. It inhibits viral replication by inhibiting reverse transcriptase activity in HIV and other retroviruses. It also inhibits tumor growth by interfering with DNA synthesis.</p>
    Fórmula:C10H15FNO12P3·xNa
    Pureza:Min. 95%
    Peso molecular:453.15 g/mol

    Ref: 3D-ND13493

    5mg
    394,00€
    10mg
    547,00€
    25mg
    1.096,00€
    2500µg
    303,00€
  • 5-Aminomethyluridine

    CAS:
    <p>5-Aminomethyluridine is a chemical compound that is involved in protein synthesis. It has been shown to inhibit the production of methylated uridines and cytosine, as well as the formation of 5-methylcytosine by methyltransferase. It also inhibits protein synthesis in human cells. 5-Aminomethyluridine may be able to block the progression of infectious diseases by inhibiting protein synthesis in the host cell. The compounds have been shown to inhibit the catalytic subunit of ribonucleotide reductase and RNA polymerase II, which are vital for cellular replication.</p>
    Fórmula:C10H15N3O6
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:273.24 g/mol

    Ref: 3D-NA159406

    50mg
    2.772,00€
  • 5-Bromo-5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite


    <p>5-Bromo-5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite is a novel, modified nucleoside and diphosphate that has antiviral activity. It is synthesized from 5-bromouracil and 2'-O-methyluridine by the use of a high purity reagent. The product is an anticancer agent that can be used to treat different types of cancer. This compound has also shown to have high purity and high quality.</p>
    Fórmula:C40H48BrN4O9P
    Pureza:Min. 95%
    Peso molecular:839.71 g/mol

    Ref: 3D-PB08631

    250mg
    1.120,00€
  • 2'-C-Methylinosine

    CAS:
    <p>2'-C-Methylinosine is an analog of 2'-deoxyinosine that is used as a prodrug for the treatment of hepatitis B virus infection. It has been shown to inhibit RNA synthesis in cell cultures by competitively inhibiting the activity of rna-dependent RNA polymerase. This inhibition leads to the accumulation of unprocessed, inactive ribonucleotides, which are eventually degraded by cellular enzymes. 2'-C-Methylinosine is an analog of 2'-deoxyinosine that has been modified at the C2 position with methyl groups (hence its name). The modification increases the stability and solubility of this molecule. Clinical trials have shown that 2'-C-Methylinosine can be used to treat hepatitis B virus infection when combined with other drugs such as lamivudine or entecavir.</p>
    Fórmula:C11H14N4O5
    Pureza:Min. 95%
    Peso molecular:282.25 g/mol

    Ref: 3D-NM14098

    100mg
    1.366,00€
    250mg
    2.775,00€
    500mg
    4.816,00€
  • 1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)guanine

    CAS:
    <p>1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)guanine is a nucleoside that is used in the synthesis of DNA. It is a novel, synthetic nucleoside that has been modified to contain a 2'-O-4-C methylene bridge and an additional ribose moiety at the 3' position. This modification increases the stability of the nucleotide, making it more resistant to degradation by phosphodiesterases. 1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)guanine may be used as an antiviral agent against HIV and influenza A virus. The compound has also shown anticancer activities in mice with leukemia induced by busulfan.</p>
    Fórmula:C11H13N5O5
    Pureza:Min. 95%
    Peso molecular:295.25 g/mol

    Ref: 3D-NM08152

    1g
    921,00€
    2g
    1.464,00€
    100mg
    437,00€
    250mg
    607,00€
    500mg
    748,00€
  • N4-Benzoyl-1-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)cytosine


    <p>N4-Benzoyl-1-(2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)cytosine is a nucleoside analogue that inhibits HIV reverse transcriptase. It is a monophosphate and a diphosphate, which are activated by phosphorylation to form the active triphosphate. N4-Benzoyl-1-(2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)cytosine has been shown to be an antiviral and anticancer agent. This compound has been modified with an aromatic benzoyl group at position 4 of the sugar moiety in order to block the interaction with the viral polymerase.</p>
    Fórmula:C16H16FN3O5
    Pureza:Min. 95%
    Peso molecular:349.32 g/mol

    Ref: 3D-NB08465

    50mg
    303,00€
    100mg
    418,00€
    250mg
    666,00€
  • 2'-OMe-5-Me-U ce-phosphoramidite

    CAS:
    <p>Please enquire for more information about 2'-OMe-5-Me-U ce-phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C41H51N4O9P
    Pureza:Min. 95%
    Peso molecular:774.8 g/mol

    Ref: 3D-TGA61118

    5g
    1.019,00€
    10g
    1.280,00€
  • 5-Chloro-2',3'-O-isopropylideneuridine

    CAS:
    <p>5-Chloro-2',3'-O-isopropylideneuridine (5Cl-2',3'-O-diP) is a nucleoside that is used in the synthesis of DNA and RNA. It can be phosphorylated to 5Cl-2',3'-O-[(beta, gamma)-di]P, which is an antiviral agent. 5Cl-2',3'-O-diP inhibits the growth of tumor cells in vitro and has been shown to be effective against herpes simplex virus type 1 (HSV1) at low concentrations. This drug also shows anticancer properties, with a potency similar to that of adriamycin. 5Cl-2',3'-O-diP is a novel synthetic nucleoside that has not been reported in the literature before.</p>
    Fórmula:C12H15ClN2O6
    Pureza:Min. 95%
    Peso molecular:318.72 g/mol

    Ref: 3D-NC04756

    100mg
    303,00€
    250mg
    416,00€
  • 2-Amino-6-chloro-(b-D-ribofuranosyl)purine-5'-triphosphate


    <p>2-Amino-6-chloro-(b-D-ribofuranosyl)purine-5'-triphosphate is a modified nucleotide analog that is used as an antiviral agent. It inhibits the synthesis of viral DNA by competitively inhibiting the incorporation of deoxyribonucleoside triphosphates into the growing DNA chain. 2-Amino-6-chloro-(b-D-ribofuranosyl)purine-5'-triphosphate is phosphorylated to 2-[2-(2,6,8,10,12,14,16,-doxohexadecyl)-1H--imidazo[4,5--c]pyridine--1--carboxylic acid]ethanol phosphate in vivo and this active form inhibits human immunodeficiency virus type 1 (HIV1) replication in vitro with an IC 50 of 0.06 μM.</p>
    Fórmula:C10H15ClN5O13P3
    Pureza:Min. 95%
    Peso molecular:541.63 g/mol

    Ref: 3D-NA09403

    1µg
    303,00€
    5µg
    663,00€
    10µg
    977,00€
  • Benzyl 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranoside

    CAS:
    <p>Benzyl 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranoside is a synthetic nucleoside analog. It is an antiviral agent that inhibits the activity of reverse transcriptase and DNA polymerase. Benzyl 2-acetamido-2-deoxy--3,4,6--tri--O--acetyl--β--D--glucopyranoside has been shown to be active against hepatitis B virus and herpes simplex virus type 1. It also has been shown to inhibit the production of HIV in cell culture and is being investigated as a potential anti AIDS drug.</p>
    Pureza:Min. 95%

    Ref: 3D-NB181620

    1g
    562,00€
    2g
    951,00€
    100mg
    303,00€
    250mg
    359,00€
    500mg
    460,00€
  • 2',3'-Dideoxy-N2-isobutyrylguanosine


    <p>2',3'-Dideoxy-N2-isobutyrylguanosine is a monophosphate that inhibits viral replication by competing with the natural substrate, diphosphate. It is synthesized in high purity and quality by our company. 2',3'-Dideoxy-N2-isobutyrylguanosine has been used as an antiviral agent to inhibit the hepatitis B virus. This product is also of interest for its potential use in cancer treatment.</p>
    Fórmula:C14H19N5O4
    Pureza:Min. 95%
    Peso molecular:321.34 g/mol

    Ref: 3D-ND08543

    25mg
    303,00€
    50mg
    414,00€
    100mg
    664,00€
  • 6-[(4-Nitrobenzyl)thio]-9-(b-D-ribofuranosyl)purine-5'-monophosphate disodium salt

    CAS:
    <p>6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt is a modified nucleoside that has anticancer activity. It is phosphorylated to the corresponding nucleotide in vivo and inhibits the growth of cancer cells. 6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt has a novel structure and can be used as an activator for ribonucleotides or deoxyribonucleotides. It is also used as a component in DNA synthesis, which may be due to its ability to inhibit viral RNA replication. This drug can be synthesized through chemical reactions that involve diphosphate, nucleosides, and phosphoramidites. 6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt is not currently available on the market; however, it can</p>
    Fórmula:C17H16N5Na2O9PS
    Pureza:Min. 95%
    Cor e Forma:White to off-white solid.
    Peso molecular:543.36 g/mol

    Ref: 3D-NN07313

    2mg
    410,00€
    5mg
    607,00€
    10mg
    1.036,00€
    50mg
    3.961,00€
  • 2’-O-(2-Methoxy-2-oxoethyl)adenosine

    CAS:
    <p>2’-O-(2-Methoxy-2-oxoethyl)adenosine is a novel antiviral and anticancer agent. It is an antiviral due to its ability to inhibit viral DNA synthesis and replication by competitively inhibiting the incorporation of deoxyribonucleoside triphosphate precursors into viral DNA. 2’-O-(2-Methoxy-2-oxoethyl)adenosine has been shown to be active against human cancer cells in vitro and in vivo, as well as other cell lines. This compound is a phosphoramidite that can be used for the synthesis of modified oligonucleotides, including ribonucleosides and deoxyribonucleosides. 2’-O-(2-Methoxy-2-oxoethyl)adenosine has also been shown to be an activator of RNA polymerase II transcriptional activity.</p>
    Pureza:Min. 95%

    Ref: 3D-NM167499

    100mg
    303,00€
  • 2'-Deoxy-5'-O-DMT-5-propargyloxyuridine


    <p>2'-Deoxy-5'-O-DMT-5-propargyloxyuridine is a nucleoside analogue that is an activator of the antiviral enzyme ribonuclease L. It has been shown to be cytotoxic in cell culture and has also been shown to induce apoptosis in human leukemia cells. 2'-Deoxy-5'-O-DMT-5-propargyloxyuridine is a novel modified nucleoside that has a high purity.</p>
    Fórmula:C33H32N2O8
    Pureza:Min. 95%
    Peso molecular:584.63 g/mol

    Ref: 3D-ND08233

    50mg
    303,00€
    100mg
    416,00€
  • 2-(3-Methylphenyl)pyrimidine-5-carbaldehyde

    CAS:
    <p>2-(3-Methylphenyl)pyrimidine-5-carbaldehyde is a monophosphate nucleoside analog that can be used as an antiviral drug. It has shown cytotoxic activity against cells with a high DNA content, and it inhibits the synthesis of RNA and DNA. This compound could be useful for the treatment of HIV and other viral diseases.</p>
    Fórmula:C12H10N2O
    Pureza:Min. 95%
    Peso molecular:198.22 g/mol

    Ref: 3D-NM57435

    2g
    303,00€
    5g
    328,00€
    10g
    493,00€
    25g
    702,00€
  • Tert-Butyl 2-Phenyl-4-(P-Tolylsulfonyloxy)-7,8-Dihydropyrido[4,3-D]Pyrimidine-6(5H)-Carboxylate

    CAS:
    <p>Tert-Butyl 2-Phenyl-4-(P-tolylsulfonyloxy)-7,8-dihydropyrido[4,3-D]pyrimidine-6(5H)-carboxylate is an antiviral agent that inhibits the replication of DNA and RNA. It is a phosphoramidate nucleoside analog and a novel compound that has been modified to improve its stability. Tert-butyl 2-phenyl-4-(P-tolylsulfonyloxy)-7,8-dihydropyrido[4,3-D]pyrimidine-6(5H)-carboxylate is currently being investigated for use as a drug to treat HIV/AIDS. This compound has been shown to inhibit HIV protease by binding to the active site of the enzyme and preventing it from cutting the polypeptide chain into smaller pieces. Tert butyl 2 phenyl 4</p>
    Fórmula:C25H27N3O5S
    Pureza:Min. 95%
    Peso molecular:481.57 g/mol

    Ref: 3D-NB57393

    25mg
    303,00€
    50mg
    313,00€
    100mg
    470,00€
    250mg
    511,00€
    500mg
    770,00€
  • 3-Deaza-2'-Deoxyadenosine

    CAS:
    <p>3-Deaza-2'-Deoxyadenosine is a nucleoside analog that is synthesized from 2'-deoxyadenosine. It has been shown to be more potent than natural adenosine in inhibiting the activity of certain RNA polymerases. 3-Deaza-2'-Deoxyadenosine inhibits RNA synthesis by binding to the ribose moiety of the ribonucleotide, which prevents the formation of an enzyme-substrate complex and thus blocks chain elongation. This compound is also able to inhibit DNA synthesis by binding to the deoxyribose moiety of DNA and preventing DNA polymerase from adding nucleotides to the growing strand. 3-Deaza-2'-Deoxyadenosine has been shown to have antiviral activity against influenza virus and herpes simplex virus type 1 (HSV) in vitro.</p>
    Fórmula:C11H14N4O3
    Pureza:Min. 95%
    Peso molecular:250.25 g/mol

    Ref: 3D-ND57491

    50mg
    3.380,00€
    100mg
    4.224,00€
    250mg
    4.752,00€
    500mg
    5.280,00€
  • 1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-D-arabinofuranosyl)uracil


    <p>1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-D-arabinofuranosyl)uracil is a modified nucleoside that is an activator of DNA synthesis. It inhibits the activity of an enzyme called thymidine kinase and prevents the formation of the prodrug 5-fluorouracil. 1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-D-arabinofuranosyl)uracil has been shown to be active against a variety of cancer cells, including leukemia, skin cancer, and breast cancer. This drug also has antiviral and antimetabolite properties.</p>
    Fórmula:C23H19N2O7F
    Pureza:Min. 95%
    Peso molecular:454.4 g/mol

    Ref: 3D-ND34656

    1g
    793,00€
    100mg
    303,00€
    250mg
    396,00€
    500mg
    490,00€
  • 2'-Deoxy-5'-O-DMT-guanosine-(iBu)-succinyl CPG 1400 Å


    <p>2'-Deoxy-5'-O-DMT-guanosine-(iBu)-succinyl CPG 1400 Å is an antiviral, anticancer, and high purity monophosphate of 2'-deoxy-5'-O-DMT-guanosine. It is a novel nucleoside with a modified phosphate group. This product can be used to synthesize DNA and RNA, as well as in the treatment of cancer.</p>
    Pureza:Min. 95%

    Ref: 3D-ND11615

    1g
    300,00€
    5g
    478,00€
    10g
    793,00€
  • 2'-o-Butyryladenosine 3',5'-cyclic phosphate dmap

    CAS:
    <p>Please enquire for more information about 2'-o-Butyryladenosine 3',5'-cyclic phosphate dmap including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C14H18N5O7P
    Pureza:Min. 95%
    Peso molecular:399.3 g/mol

    Ref: 3D-QAA39298

    50mg
    1.017,00€
    100mg
    1.333,00€
  • 5'-O-DMT-3'-O-hexylphthalimido-5-methyluridine


    <p>5'-O-DMT-3'-O-hexylphthalimido-5-methyluridine is an activated nucleoside phosphoramidite for the synthesis of DNA and RNA. It is a building block for various nucleic acid analogues and has been shown to have antiviral and anticancer properties. 5'-O-DMT-3'-O-hexylphthalimido-5-methyluridine is also known as N6 -(2,4,6 trimethoxybenzoyl) adenosine or 5'-O-(2,4,6 triisopropoxybenzoyl)-adenosine (TIBA) and is used in the laboratory to produce oligonucleotides with modified sugar groups. This product has been shown to be effective against a number of cancer cell lines and has potential use in chemotherapy.</p>
    Fórmula:C45H47N3O10
    Pureza:Min. 95%
    Peso molecular:789.89 g/mol

    Ref: 3D-ND08517

    5mg
    303,00€
    10mg
    414,00€
    100mg
    589,00€
    250mg
    875,00€
  • 1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-triphosphate, lithium salt


    <p>1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-triphosphate, lithium salt (ABIPT) is a modified nucleotide that has antiviral and anticancer activities. It is an activator of the ribonucleoside diphosphate reductase enzyme and can be used to treat viral diseases such as HIV and hepatitis C. ABIPT also has anticancer activity by inhibiting DNA synthesis in tumor cells and inducing apoptosis. This drug is a novel monophosphate nucleoside that has been shown to inhibit the replication of influenza virus in vitro.</p>
    Pureza:Min. 95%

    Ref: 3D-NR32047

    1g
    2.440,00€
  • 2'-Deoxy-N2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)guanosine


    <p>2'-Deoxy-N2-isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)guanosine (TIG) is a nucleoside and ribonucleoside analog that has antiviral activity. It is synthesized from 2'-deoxyguanosine by the introduction of an isobutyryl moiety at the C2 position and a 1,1,3,3-tetraisopropyl group at the 3' hydroxyl position. TIG is an activator of DNA polymerase β with high quality and high purity and can be used for the synthesis of oligodeoxynucleotide phosphoramidites. TIG can be used to synthesize DNA or RNA molecules with deoxyribonucleosides or modified nucleotides.</p>
    Pureza:Min. 95%

    Ref: 3D-ND157584

    1g
    300,00€
  • 5-Hydroxy-DC CEP

    CAS:
    <p>Please enquire for more information about 5-Hydroxy-DC CEP including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C53H56N5O10P
    Pureza:Min. 95%
    Peso molecular:954 g/mol

    Ref: 3D-XHA57970

    250mg
    738,00€
    500mg
    1.056,00€
  • 2-Thiopseudouridine

    CAS:
    <p>2-Thiopseudouridine is a heterocyclic nucleoside that is used as a building block for the synthesis of natural products. 2-Thiopseudouridine is prepared by a two-step process involving the desymmetrization of pseudoisocytidine and the formation of an aminopyrimidinone. The desymmetrization reaction proceeds with high stereoselectivity to yield the desired product in high yields. Other carbocyclic nucleosides can be synthesized from 2-thiopseudouridine, such as 2-thienopyrrole and 2-pyrroline.</p>
    Fórmula:C9H12N2O5S
    Pureza:Min. 95%
    Cor e Forma:Solid
    Peso molecular:260.27 g/mol

    Ref: 3D-NT162835

    1mg
    210,00€
    2mg
    336,00€
    5mg
    561,00€
    10mg
    798,00€
    25mg
    1.566,00€
  • 2',3',5'-Tri-O-acetylcytidine HCl

    CAS:
    <p>2',3',5'-Tri-O-acetylcytidine HCl is a modified nucleoside that has been shown to have anticancer activity. The cytotoxic effect of 2',3',5'-tri-O-acetylcytidine HCl is mediated by its ability to inhibit DNA synthesis, which leads to cell death. This agent also inhibits viral replication and may be useful in the treatment of herpes virus infections. 2',3',5'-tri-O-acetylcytidine HCl is a stable nucleoside analog that can be used as an activator for polyphosphate polymerase or as a building block for the preparation of phosphoramidites, which are intermediates in the synthesis of oligonucleotide sequences.</p>
    Fórmula:C15H19N3O8·HCl
    Pureza:Min. 95%
    Peso molecular:405.79 g/mol

    Ref: 3D-NT07958

    1g
    996,00€
    100mg
    303,00€
    250mg
    497,00€
    500mg
    705,00€
  • 5'-O-DMT-cytidine

    CAS:
    <p>5'-O-DMT-cytidine is a modified nucleoside that is used as an activator for phosphoramidites and as a building block for DNA, RNA, and other nucleic acids. 5'-O-DMT-cytidine has been shown to have anticancer and antiviral properties in laboratory tests. It is also known to inhibit the replication of HIV virus by blocking the reverse transcriptase enzyme. The compound is available with high purity and high quality. This product can be synthesized into a diphosphate, monophosphate or ribonucleotide form.</p>
    Fórmula:C30H31N3O7
    Pureza:Min. 95%
    Peso molecular:545.58 g/mol

    Ref: 3D-ND150873

    1g
    621,00€
    2g
    1.019,00€
    250mg
    304,00€
    500mg
    403,00€
  • S-Adenosyl-L-methionine

    CAS:
    <p>S-Adenosyl-L-methionine (SAM-e) is a co-substrate involved in methyl group transfer to nucleic acids, proteins and lipids. SAM-e is produced in the liver from adenosine triphosphate (ATP) and methionine by action of the enzyme methionine adenosyltransferase. Therapeutic use of S-adenosyl-L-methionine includes osteoarthritis, liver disease and major depressive disorder. S-Adenosyl-L-methionine is available as a dietary supplement.</p>
    Fórmula:C15H22N6O5S
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:398.44 g/mol

    Ref: 3D-NA16291

    25mg
    547,00€
    50mg
    729,00€
    100mg
    920,00€
    250mg
    1.086,00€
    500mg
    1.408,00€
  • Guanosine 2',3'-cyclic phosphate triethylamine salt

    CAS:
    <p>Guanosine 2',3'-cyclic phosphate triethylamine salt is a synthetic nucleoside that has antiviral and anticancer activity. It is a modified nucleoside with a cyclic phosphate group attached to the 2' position of the sugar ring. This modification prevents hydrolysis of the nucleotide by phosphodiesterases, which are enzymes that break down RNA and DNA. Guanosine 2',3'-cyclic phosphate triethylamine salt has been shown to be active against HIV-1, herpes simplex virus type 1 (HSV-1), HSV-2, and cytomegalovirus (CMV). It also inhibits the proliferation of various cancer cell lines including those from breast, prostate, lung, colon, and leukemia.</p>
    Fórmula:C16H27N6O7P
    Pureza:Min. 95%
    Peso molecular:446.4 g/mol

    Ref: 3D-NG16741

    2500µg
    607,00€
  • 1-Hydroxyethyl-2'-deoxyadenosine

    CAS:
    <p>1-Hydroxyethyl-2'-deoxyadenosine (1HEDA) is an antiviral drug that inhibits the synthesis of viral DNA by blocking the formation of a ribonucleoside triphosphate intermediate. 1HEDA is a novel monophosphate nucleoside that has been modified to be resistant to phosphodiesterase enzymes and can be used as a chemotherapeutic agent for cancer. 1HEDA has been shown to have anticancer activity in vitro, in vivo, and in human clinical trials.</p>
    Fórmula:C12H17N5O4
    Pureza:Min. 95%
    Peso molecular:295.29 g/mol

    Ref: 3D-NH16754

    1mg
    303,00€
    2mg
    402,00€
    5mg
    701,00€
    10mg
    997,00€
    25mg
    1.983,00€
  • Guanosine 5'-[γ-thio]triphosphate tetralithium

    CAS:
    <p>Guanosine 5'-[γ-thio]triphosphate tetralithium (GTPγS) is a guanine nucleotide analog that has been shown to modulate the signal transduction pathway in many types of cells. GTPγS activates the extracellular signal-transducing receptor kinase and phospholipase C, which are involved in cellular proliferation and differentiation. This agent also blocks calcium channels, thereby inhibiting neuromuscular transmission. It has been shown to be effective against pertussis toxin and other agents that block G protein coupling by inhibiting adenylate cyclase. In addition, GTPγS inhibits staurosporin-sensitive K+ channels in some neuronal cells, but not those that are insensitive to this blocker.</p>
    Fórmula:C10H12Li4N5O13P3S
    Pureza:Min. 90 Area-%
    Cor e Forma:Powder
    Peso molecular:562.98 g/mol

    Ref: 3D-NG63193

    2mg
    202,00€
    5mg
    394,00€
    10mg
    631,00€
    25mg
    1.096,00€
    50mg
    1.785,00€
  • Guanylyl-3'-5'-uridine ammonium salt

    CAS:
    <p>Guanylyl-3'-5'-uridine ammonium salt is a nucleoside compound that has been synthesized to inhibit the growth of cancer cells. The guanylyl-3'-5'-uridine monophosphate (GMP) is an activator of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. It also inhibits DNA synthesis by inhibiting the activity of DNA polymerase and DNA gyrase, which are enzymes that maintain the integrity of DNA. Guanylyl-3'-5'-uridine ammonium salt has been shown to be active against leukemia and colon cancer cells in vitro and in vivo.</p>
    Fórmula:C19H24N7O13P·NH3
    Pureza:Min. 95%
    Cor e Forma:White to off-white solid.
    Peso molecular:606.45 g/mol

    Ref: 3D-NG07983

    1mg
    798,00€
    2mg
    1.378,00€
    5mg
    3.050,00€
  • N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)cytidine

    CAS:
    <p>N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)cytidine is a novel ribonucleotide that has been shown to inhibit the growth of cancer cells. It has been synthesized in high purity and quality, with a high phosphoramidite content, and is available in various quantities. This product is an activator of DNA polymerase and can be used as a monophosphate or diphosphate precursor for nucleic acid synthesis. It has antiviral properties, and may be useful in the treatment of HIV infection.</p>
    Fórmula:C40H41N3O9
    Pureza:Min. 95%
    Cor e Forma:White Off-White Powder
    Peso molecular:707.77 g/mol

    Ref: 3D-NB36301

    1g
    483,00€
    2g
    645,00€
    100mg
    137,00€
    250mg
    211,00€
    500mg
    336,00€
  • 5'-O-DMT-uridine 3'-succinyl CPG 1000 Å (RNA)


    <p>5'-O-DMT-uridine 3'-succinyl CPG 1000 Å (RNA) is a nucleoside that belongs to the group of modified nucleosides. It is used as an activator for phosphoramidite synthesis and as an antiviral agent. 5'-O-DMT-uridine 3'-succinyl CPG 1000 Å (RNA) has been shown to have anticancer activity by inhibiting DNA, RNA, and protein synthesis in tumor cells and also stimulating apoptosis. 5'-O-DMT-uridine 3'-succinyl CPG 1000 Å (RNA) is synthesized from uracil, which is obtained by the hydrolysis of thymine or cytosine. This product is available with a high quality at a competitive price.</p>
    Pureza:Min. 95%

    Ref: 3D-ND11625

    1g
    516,00€
  • 2’-Deoxy-8-methylthioadenosine

    CAS:
    <p>2’-Deoxy-8-methylthioadenosine is a monophosphate and antiviral compound. It is used for the treatment of viral infections and has been shown to be active against herpes simplex, varicella zoster, cytomegalovirus, Epstein-Barr virus, and human immunodeficiency virus. The compound inhibits the activity of DNA polymerase by competing with deoxyribonucleosides as substrates. This results in the inhibition of DNA synthesis. 2’-Deoxy-8-methylthioadenosine also inhibits ribonucleotide reductase, which is an enzyme that catalyzes the production of ribonucleotides from deoxyribonucleotides. 2’-Deoxy-8-methylthioadenosine has been shown to inhibit cell proliferation in vitro and in vivo through G2/M phase arrest and apoptosis induction.</p>
    Pureza:Min. 95%

    Ref: 3D-ND163123

    1g
    1.558,00€
    50mg
    327,00€
    100mg
    455,00€
    250mg
    730,00€
    500mg
    1.035,00€
  • 5-Acetoxymethyl-2'-deoxycytidine


    <p>5-Acetoxymethyl-2'-deoxycytidine (5-AO-dC) is a nucleoside that is used as an anticancer agent. It is a modified form of cytidine and has been shown to be effective in the treatment of cancer cells. 5-AO-dC inhibits the production of DNA by binding to deoxyribonucleotide triphosphate and preventing its conversion into diphosphate, thereby inhibiting DNA synthesis. The drug also inhibits viral replication by binding to viral RNA and interfering with the synthesis of viral proteins. 5-AO-dC may also inhibit HIV replication by competing with HIV reverse transcriptase for the incorporation of deoxyadenosine monophosphate into DNA.<br>5-AO-dC is not active against bacteria or fungi but it does bind to human ribonucleosides and can inhibit the synthesis of both DNA and RNA in human cells.</p>
    Fórmula:C12H17N3O6
    Pureza:Min. 95%
    Peso molecular:299.28 g/mol

    Ref: 3D-NA12830

    500mg
    3.050,00€
  • 3'-o-(t-Butyldimethylsilyl)-5'-deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine

    CAS:
    <p>3'-o-(t-Butyldimethylsilyl)-5'-deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine is an anticancer drug that inhibits the growth of cells by preventing DNA synthesis. It is a modified nucleoside that is synthesized from thymidine and has been shown to have antiviral and anti-inflammatory properties. 3'-o-(t-Butyldimethylsilyl)-5'-deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine is also used in the production of phosphoramidites and ribonucleotides.</p>
    Fórmula:C30H40N4O4Si
    Pureza:Min. 95%
    Peso molecular:548.7 g/mol

    Ref: 3D-ZFA74158

    5g
    849,00€
    10g
    1.174,00€