
Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
N4-Acetyl-1-(2'-O-acetyl-5'-O-DMT-b-D-arabinofuranosyl)cytosine 3'-CE phosphoramidite
<p>N4-Acetyl-1-(2'-O-acetyl-5'-O-DMT-b-D-arabinofuranosyl)cytosine 3'-CE phosphoramidite is a novel nucleoside designed for DNA activation. It has high quality and high purity, which are essential for pharmaceutical and analytical applications. This product is used in the synthesis of DNA, antiviral drugs, and anti-cancer agents. N4-Acetyl-1-(2'-O-acetyl-5'-O-DMT b -D -arabinofuranosyl)cytosine 3'-CE phosphoramidite can be used as an activator in the synthesis of deoxyribonucleosides and ribonucleosides.</p>Fórmula:C22H34N5O8PPureza:Min. 95%Peso molecular:527.51 g/mol2-Iodo-2’-deoxyadenosine
CAS:<p>2-Iodo-2’-deoxyadenosine is a novel nucleoside that is a modified adenosine. It has been shown to possess anticancer activity. 2-Iodo-2’-deoxyadenosine has a high degree of cytotoxicity and can induce apoptosis in cancer cells. This drug also inhibits the growth of herpes simplex virus type 1 (HSV) and HIV, which are both types of viruses that infect humans. The antiviral activity may be due to the inhibition of viral DNA synthesis or RNA transcription. 2-Iodo-2’-deoxyadenosine is synthesized from adenine, iodine, and sulfuric acid with high purity and quality. It is not active against bacteria because it does not inhibit bacterial DNA gyrase or topoisomerase IV enzymes.</p>Pureza:Min. 95%8-(p-Chlorophenylthio)-cGMP
CAS:<p>8-(p-Chlorophenylthio)-cGMP is a modified nucleoside that has anticancer activity. It inhibits DNA synthesis and the activation of protein kinases, which are enzymes that transmit signals from the cell surface to the nucleus. 8-(p-Chlorophenylthio)-cGMP can also inhibit viral replication by inhibiting the production of new virus particles and by inhibiting the action of reverse transcriptase, an enzyme that converts RNA into DNA.</p>Fórmula:C16H15ClN5O7PSPureza:Min. 95%Peso molecular:487.81 g/mol2'-O-Allylguanosine
CAS:<p>2'-O-Allylguanosine is an intermediate in the synthesis of 2,6-diaminopurine riboside. It is synthesized from allyl chloride and guanosine by an allylation reaction. The yield for this reaction is high, which makes it a useful synthon. Deamination of the product yields 2'-O-allylguanosine 5'-monophosphate, which can be converted to 2',6-diaminopurine riboside by hydrolysis with phosphoric acid. This intermediate is used in research on nucleic acids sequences and hydrogen bonding.</p>Fórmula:C13H17N5O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:323.3 g/mol5'-O-DMT-N4-isobutyryl-2'-O-methyl-5-methylcytidine
<p>5'-O-DMT-N4-isobutyryl-2'-O-methyl-5-methylcytidine, also known as 5'-O-(4,4'-dimethoxytrityl)-N4-isobutyryl-2'-O-methyl-5-methylcytidine, is a nucleoside and nucleotide analog. It is an antiviral agent with anticancer activity. This compound has been shown to be highly active against herpes simplex virus type 1 (HSV1) in vitro. The mechanism of action is not yet fully understood but may involve modification of the viral DNA polymerase.</p>Fórmula:C36H41N3O8Pureza:Min. 95%Peso molecular:643.73 g/mol2'-Deoxy-N4,5-dimethylcytidine
CAS:<p>2'-Deoxy-N4,5-dimethylcytidine is an activator that has the ability to activate a variety of nucleoside analogs. The compound is synthetically derived and used as an antiviral agent. It can be modified at the 5' position with phosphate groups or ribonucleosides. 2'-Deoxy-N4,5-dimethylcytidine is also a novel monophosphate nucleoside that has been shown to inhibit the growth of cancer cells in vitro and in vivo. This drug inhibits DNA synthesis by preventing the incorporation of diphosphate nucleotides into DNA during DNA replication. 2'-Deoxy-N4,5-dimethylcytidine is not active against RNA synthesis because it does not have any activity at this site.</p>Fórmula:C11H17N3O4Pureza:Min. 95%Peso molecular:255.27 g/mol4-Bromo-2-methoxypyrimidine
CAS:<p>4-Bromo-2-methoxypyrimidine is a synthetic compound that is used in the synthesis of other compounds. It reacts with alcohols, boronic acids, and benzyl halides to form heterocycles or pyrimidine compounds. The reaction system is catalytic and chemoselectively. 4-Bromo-2-methoxypyrimidine has been shown to have anticancer activity against various cell lines in vitro. It also possesses an ability to react with aryl boronic acids, such as those found in 2-pyridinones, to form new compounds. This reaction is catalyzed by palladium on carbon or copper chloride in the presence of a base. The new compounds have shown anti-inflammatory and cytotoxic activities against cancer cells.</p>Pureza:Min. 95%3'-deoxy-3',4'-didehydrouridine
CAS:<p>3'-deoxy-3',4'-didehydrouridine is a synthetic nucleoside that inhibits viral replication. It is an antiviral agent that has been shown to be effective against DNA and RNA viruses. The synthesis of this compound has been described in the literature. This product is available in high purity and high quality, and CAS No. 2166167-51-5. 3'-deoxy-3',4'-didehydrouridine has also been shown to have anticancer activity, and is a novel synthetic nucleoside.</p>Fórmula:C9H10N2O5Pureza:Min. 95%Peso molecular:226.19 g/molFialuridine 5'-monophosphate
CAS:Fialuridine 5'-monophosphate is an analog of fialuridine, a drug used to treat HIV. Fialuridine 5'-monophosphate inhibits mitochondrial DNA synthesis by inhibiting hepg2 in the mitochondria and blocks the conversion of uracil to thymine in nuclear DNA. The inhibition of these two processes prevents viral replication and cell division. Fialuridine 5'-monophosphate also has antioxidant properties that protect cells from oxidative damage induced by reactive oxygen species. This drug may be beneficial for cancer treatment as well as hepatitis C or herpes simplex virus infection.Fórmula:C9H11FIN2O8PPureza:Min. 95%Peso molecular:452.07 g/mol5-Aza-3-deaza-N4-DMF-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
<p>5-Aza-3-deaza-N4-DMF-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is a novel modified nucleoside that is synthesized by the reaction of 5-Aza-3,8-(N4,N4)-dimethyl-1,2:5,6:8:10,11:12,-tetradeoxyribonucleosides with 2'-O,O'-Dimethoxytrityl Chloride. This product has been shown to be an activator and to have antiviral and anticancer activities. It also has a high purity and quality.</p>Fórmula:C43H55N6O8PPureza:Min. 95%Peso molecular:814.91 g/mol3'-Deoxy-3'-fluoroinosine
CAS:3'-Deoxy-3'-fluoroinosine is a nucleoside analog that has been shown to have cytotoxic effects. It inhibits the growth of nematodes and other parasites by blocking the deacetylation of lipids in the cell membrane, which leads to their death. 3'-Deoxy-3'-fluoroinosine has also been shown to inhibit trypanosomiasis and leishmania infections by preventing the synthesis of purines and pyrimidines. This drug binds to 6-chloropurine ribonucleotide reductase, thereby inhibiting the production of nucleic acids. 3'-Deoxy-3'-fluoroinosine is not active against mammalian cells, which may be due to its inability to penetrate cell membranes efficiently.Pureza:Min. 95%Pyrrolo-2’-deoxycytidine 3’-CE phosphoramidite
CAS:A fluorescent analogue of deoxycytidine. Used for monitoring RNA secondary structure formation, where its fluorescence is reversibly quenched upon base-pairing. Emission max is at 473nm.Fórmula:C42H50N5O7PPureza:Min. 95%Peso molecular:767.8 g/mol2'-Deoxy-5'-O-DMT-uridine 3'-succinyl CPG 1000Å
<p>2'-Deoxy-5'-O-DMT-uridine 3'-succinyl CPG 1000Å is an anticancer drug that is used in the treatment of acute myeloid leukemia. This compound is a modified nucleoside. It has been shown to inhibit the growth of cultured cells and induce apoptosis by causing DNA damage. The anticancer properties of 2'-deoxy-5'-O-DMT-uridine 3'-succinyl CPG 1000Å are mediated by its inhibition of DNA synthesis, RNA synthesis, and protein synthesis.</p>Pureza:Min. 95%5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 5'-triphosphate
CAS:5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 5'-triphosphate (AICAR) is a bifunctional agent that has been shown to stimulate the activity of adenylosuccinate synthetase, an enzyme that catalyzes the conversion of adenosine monophosphate (AMP) to adenosine triphosphate (ATP). AICAR is also a substrate for adenylosuccinate synthetase. The use of AICAR as a pharmacological agent has been associated with increased levels of nucleotides in cells and tissues. This may be due to the activation of AMPK, which stimulates ATP production by breaking down ATP through oxidative phosphorylation. AICAR can be detected using chromatographic techniques, such as high performance liquid chromatography or thin layer chromatography.Fórmula:C9H17N4O14P3Pureza:Min. 95%Peso molecular:498.17 g/mol3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine
<p>3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine is an antiviral agent that belongs to the class of nucleosides. It is a novel phosphoramidite which can be used in the synthesis of ribonucleosides and deoxyribonucleosides. 3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine has shown anticancer activity, with a potential use as an inhibitor of cellular proliferation, including tumor cells. 3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine also inhibits viral replication by interfering with the initiation and elongation steps of viral DNA synthesis.</p>Pureza:Min. 95%5'-O-DMTr-2'-O,4'-C-methyleneuridine 3'-CE-phosphoramidite
CAS:5'-O-DMTr-2'-O,4'-C-methyleneuridine 3'-CE-phosphoramidite is a novel nucleoside phosphoramidite. It is an activator of DNA polymerase for the synthesis of diphosphate analogues of ribonucleosides and deoxyribonucleosides. This compound has been used in the synthesis of antiviral and anticancer agents, as well as in research on the development of new antiviral drugs.Pureza:Min. 95%Myristoyl coenzyme A lithium salt
CAS:<p>Myristoyl coenzyme A lithium salt is an activator that can be used in the synthesis of Ribonucleosides and Deoxyribonucleosides. It has a high purity, which ensures high quality synthesis. Myristoyl coenzyme A lithium salt is a novel nucleotide precursor that can be used to synthesize DNA or RNA for use in anti-cancer or antiviral treatments.</p>Fórmula:C35H62N7O17P3S·xLiPureza:Min. 95%Peso molecular:977.89 g/mol2,2’-Anhydro-5’-O-DMT-uridine
CAS:2,2’-Anhydro-5’-O-DMT-uridine is a high purity synthetic nucleoside that is modified with a hydroxymethyl group in the 2' position. It is a monophosphate and diphosphate derivative of uridine. This nucleoside has antiviral and anticancer properties, as well as the ability to inhibit HIV replication.Fórmula:C30H28N2O7Pureza:Min. 95%Peso molecular:528.55 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite is a modified nucleoside that can be used to synthesize oligonucleotides. The 2'-O group is a protecting group and the 5' hydroxyl group is the site of attachment for the phosphate group. This product is an anticancer, antiviral, and antiretroviral agent. It has been shown to inhibit the growth of cancer cells in vitro and in vivo.</p>Fórmula:C45H60IN4O9PSiPureza:Min. 95%Peso molecular:986.97 g/mol2'-Deoxy-5'-O-DMT-5-methylcytidine
CAS:<p>2'-Deoxy-5'-O-DMT-5-methylcytidine is a nucleoside analog that can be used to treat cancer. This compound is synthesized by the conversion of 5′-O-dimethoxytrityl (DMT)-2'-deoxycytidine to its 5′-O-DMT phosphoramidite. The phosphoramidite is then reacted with methylene chloride, methanol, and ammonia to form the monophosphate. 2'-Deoxy-5'-O-DMT-5-methylcytidine has been shown to be an effective anticancer drug in vitro and in vivo. It targets DNA synthesis, which prevents the duplication of genetic material necessary for cell division.</p>Fórmula:C31H33N3O6Pureza:Min. 95%Cor e Forma:White to off-white solid.Peso molecular:543.63 g/mol8-(4-Aminophenyl)-2'-deoxyguanosine
<p>8-(4-Aminophenyl)-2'-deoxyguanosine is an Activator that has novel properties. It is a diphosphate of 8-(4-Aminophenyl)thymidine and is also known as 8-APT. It has been shown to have anticancer and antiviral activity in animal models, and it may be a potential treatment for HIV infection. The chemical name for 8-APT is 2'-deoxyguanosine, 8-(4-aminophenyl)-, (8R*,9S*)-.</p>Fórmula:C16H18N6O4Pureza:Min. 95%Peso molecular:358.35 g/mol6-Aminothymine
CAS:<p>6-Aminothymine is a polyamine that exerts its inhibitory activity by hydrogen bonding to the enzyme's active site. It has been shown to inhibit protein synthesis and growth factor synthesis in HL-60 cells. 6-Aminothymine also has cancer inhibiting properties, which may be due to its ability to bind DNA and interfere with replication or transcription.</p>Fórmula:C5H7N3O2Pureza:Min. 95%Peso molecular:141.13 g/mol1-(2',3',5'-Tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-4-carbonitrile
CAS:Ribonucleosides are nucleoside derivatives that can be used as antiviral agents. Ribonuclease (RNase) is a type of ribonucleoside that acts as an antiviral agent by inhibiting the synthesis of RNA in cells. Ribonuclease has been shown to inhibit the growth of HIV-1 and HIV-2 in vitro, and may also have therapeutic potential for other viruses such as herpes simplex virus-1 (HSV-1). Ribonuclease is synthetically modified to produce 1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-[4,5,-c]-carbonitrile, an activator ribonucleoside with high purity and novel properties.Fórmula:C29H53N3O4Si3Pureza:Min. 95%Peso molecular:592.01 g/mol3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine
<p>3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine is a novel nucleoside analog that has been shown to have anticancer activity in vitro. The compound is a monophosphate, which is synthesized from 2'-deoxyuridine and benzoyl chloride. 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine was found to have antiviral activity against herpes simplex virus type 1 (HSV1) and cytomegalovirus (CMV). It also inhibited the production of HIV in human lymphocytes. This nucleoside analog can be activated by phosphorylation at the 5' position to form a diphosphate, which inhibits DNA synthesis by incorporating into the growing DNA chain and preventing the movement of RNA polymerase along the template strand.</p>Fórmula:C23H19FN2O7Pureza:Min. 95%Peso molecular:454.42 g/mol6-(Trifluoromethyl)uracil
CAS:6-(Trifluoromethyl)uracil is a synthetic analog of uracil, which is a nucleobase that is found in RNA. It can be synthesized by reacting phosphorus oxychloride and trifluoromethyl chloride to form the corresponding chloroformate ester, followed by hydrolysis with anhydrous potassium carbonate. The compound has been shown to inhibit bacterial growth in bioassays and also has the ability to react with amines. 6-Trifluoromethyluracil has a constant chlorine atom that forms hydrogen bonds with other molecules, such as ammonia or amines, which may have antibacterial properties.Fórmula:C5H3F3N2O2Pureza:Min. 95%Peso molecular:180.08 g/mol5'-O-tert-Butyldimethylsilyluridine
CAS:<p>5'-O-tert-Butyldimethylsilyluridine (5'-O-TBDMSU) is a nucleoside that is used in the synthesis of nucleic acid probes. It is selective for the uridine residues in RNA and DNA, which are found at the 5' position. Sodium hydride reacts with this compound to form the corresponding hydroxyl group. This allows for further nucleobase additions or halogen substitutions to be made to the molecule, as well as desilylation reactions. 5'-O-TBDMSU can also be used to synthesize heteroaromatic nucleic acids and nucleotide derivatives.</p>Fórmula:C15H26N2O6SiPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:358.46 g/mol2,6-Dichloro-9-(2'-deoxy-b-D-ribofuranosyl)purine
CAS:<p>2,6-Dichloro-9-(2'-deoxy-β-D-ribofuranosyl)purine is a synthetic compound that is used in the treatment of certain types of cancer. It has been shown to be an activator of DNA synthesis and an inhibitor of RNA synthesis. It has also been shown to inhibit tumor growth and prolong the survival time for patients with leukemia. The antiviral activity of 2,6-dichloro-9-(2'-deoxy-β-D-ribofuranosyl)purine may be due to its ability to inhibit viral DNA polymerase. This drug is also known as dideoxyinosine (ddI).</p>Fórmula:C10H10Cl2N4O3Pureza:Min. 95%Peso molecular:305.12 g/mol3-Deazauridine-5'-triphosphate triethylamine salt
CAS:3-Deazauridine-5'-triphosphate triethylamine salt is a xanthosine analog that has been used as a biochemical reagent in animals and humans. It is postulated to be a potential cancer therapeutic agent because of its ability to inhibit DNA synthesis and cell division. 3-Deazauridine-5'-triphosphate triethylamine salt inhibits the biosynthesis of uridine in leukemic mice, hamster V79 cells, and mammalian cells. This drug inhibits the incorporation of uracil into RNA by competitive inhibition with respect to ATP. 3DATTP also inhibits the incorporation of thymidine into DNA by competitive inhibition with respect to dCTP.Fórmula:C10H16NO15P3Pureza:Min. 95%Peso molecular:483.15 g/mol8-Oxo-N2-isobutyryl-2-deoxyguanosine
CAS:<p>8-Oxo-N2-isobutyryl-2-deoxyguanosine is a modified synthetic nucleoside. It finds applications in understanding mutagenesis and DNA repair mechanisms.</p>Fórmula:C14H19N5O6Pureza:Min. 95%Peso molecular:353.33 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyryl-guanosine-3'-lcaa-CPG
<p>2'-Deoxy-5'-O-DMT-N2-isobutyryl-guanosine-3'-lcaa-CPG is a modified nucleoside, which is synthetically prepared. It is an activator of DNA polymerase and has been shown to be active against human leukemia cells. 2'-Deoxy-5'-O-DMT-N2-isobutyryl Guanosine 3'-lcaa CPG has also been shown to inhibit the replication of the herpes simplex virus type 1 in vitro. The compound is a novel high quality nucleoside phosphoramidite that can be used as a building block in the synthesis of deoxyribonucleosides and modified nucleosides with novel chemical structures.</p>Pureza:Min. 95%N6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite
CAS:N6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite is a novel modified nucleoside that has antiviral, anticancer and antibacterial properties. The chemical name is N6-benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite. It is a ribonucleotide. It is an activator of the enzyme kinase A which phosphorylates proteins and activates them. This product has not been tested in humans.Fórmula:C47H52N7O7PPureza:Min. 95%Peso molecular:857.93 g/molAdenosine 5′-diphosphoribose monosodium
CAS:Adenosine 5′-diphosphoribose monosodium is a novel nucleotide that can be used in the synthesis of antiviral, anticancer, and anti-inflammatory drugs. Adenosine 5′-diphosphoribose monosodium is a modified form of adenosine 5′-triphosphate (ATP) with an added phosphate group at the 5′ position on the ribose sugar. It is synthesized from ATP by phosphoramidite chemistry. The CAS number for this product is 68414-18-6. Adenosine 5′-diphosphoribose monosodium has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) and herpes simplex virus type 1 (HSV-1).Fórmula:C15H23N5O14P2•NaPureza:Min. 95%Peso molecular:582.31 g/molCytidine hemisulfate salt
CAS:Cytidine hemisulfate salt is a postulated inhibitor of the blood group antigen. It inhibits the phosphatase activity of blood group-specific phosphatases, which may be caused by its specific inhibition of α-tocopherol and phenolphthalein. Cytidine hemisulfate salt has been shown to inhibit both adenylic and uridylic phosphatases, but does not inhibit other phosphatases. This drug is also an antigen that can stimulate B cells, which produce antibodies against it. Cytidine hemisulfate salt is found in DNA and RNA.Fórmula:C9H13N3O5H2SO4Pureza:Min. 95%Peso molecular:292.26 g/mol5'-Fluoro-5'-deoxy-adenosine
CAS:5'-Fluoro-5'-deoxy-adenosine (FDA) is a fluorinated adenosine derivative that has been shown to regulate glucose levels in plasma. It has been shown to increase the uptake of glucose in cells and improve insulin sensitivity, which may be due to its ability to increase the production of nitric oxide. FDA is also thought to act as an antioxidant and may be useful for treating autoimmune diseases such as insulin resistance and type II diabetes.Fórmula:C10H12FN5O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:269.23 g/mol5'-O-p-Anisoyl-3'-fluoro-3'-deoxythymidine
<p>5'-O-p-Anisoyl-3'-fluoro-3'-deoxythymidine is a novel anticancer agent that has been shown to be active against leukemia, lymphoma and myeloma. The compound is a nucleoside analogue that inhibits DNA synthesis by inhibiting the activity of DNA polymerase. It has been shown to have antiviral activity in vitro against herpes simplex virus type 1 and type 2, influenza A virus and HIV. 5'-O-p-Anisoyl-3'-fluoro-3'-deoxythymidine can also inhibit protein synthesis by blocking the incorporation of amino acids into protein. This drug is synthesized from 3',5'-dideoxyuridine (dU) and fluoroacetyl chloride to produce 5'-O-p-anisoyl-3',5'-difluoroacetyl dU (ADUF). ADUF is then reacted with anisole to produce 5</p>Fórmula:C18H19FN2O6Pureza:Min. 95%Peso molecular:378.4 g/mol2'-Deoxy-N6,N6-dimethyladenosine
2'-Deoxy-N6,N6-dimethyladenosine is a novel nucleoside that has been shown to inhibit the growth of cancer cells. It binds to DNA and inhibits the activity of bacterial RNA polymerase, which prevents transcription and replication. The monophosphate form of 2'-deoxy-N6,N6-dimethyladenosine is an activator for ribonucleotide reductase and an inhibitor for DNA gyrase. This drug also inhibits viral replication by inhibiting viral reverse transcriptase. 2'-Deoxy-N6,N6-dimethyladenosine has been shown to have antiviral activity against influenza virus type A (H1N1) and HIV in cell culture. This drug is chemically synthesized using phosphoramidites as raw materials and purified by high performance liquid chromatography (HPLC). The CAS number is 220763-81-8.Pureza:Min. 95%4'-a-C-Methyladenosine
CAS:<p>4'-a-C-Methyladenosine is a nucleoside that has antiviral, anticancer and novel properties. It is a modified nucleoside with a methyl group in the 4' position. This modification prevents the phosphodiester bond from being hydrolyzed by nucleotide kinase enzymes. The methyl group also inhibits the formation of adenosine monophosphate (AMP) during DNA synthesis, which prevents the deactivation of adenosine triphosphate (ATP). 4'-a-C-Methyladenosine is used to synthesize oligonucleotides for use in DNA sequencing and gene mapping.</p>Pureza:Min. 95%5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine
CAS:<p>5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine is a synthetic, modified nucleoside that functions as an activator of ribonucleotide reductase. It has been shown to be effective in the treatment of viral infections, including herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and human immunodeficiency virus type 1 (HIV-1). 5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine is also synthesized into DNA or RNA molecules, which are used to study the structure of these compounds. It can also be used for phosphoramidite synthesis.</p>Fórmula:C20H27F3N4OPureza:Min. 95%Peso molecular:396.45 g/mol3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite
CAS:<p>3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite is a novel nucleoside, which is structurally similar to cytidine and has been synthesized for the first time. 3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite has antiviral and anticancer activities. It inhibits the growth of viruses by inhibiting DNA synthesis. 3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite also inhibits the growth of cancer cells by inhibiting RNA synthesis.</p>Fórmula:C43H53N8O7PPureza:Min. 95%Peso molecular:824.9 g/molStavudine 5'-monophosphate triethyammonium salt
<p>Stavudine 5'-monophosphate triethylammonium salt is a nucleoside analog that is structurally related to the natural deoxyribonucleosides. It has antiviral activity and is used in the treatment of HIV-1. Stavudine 5'-monophosphate triethylammonium salt inhibits viral replication by inhibiting DNA polymerase, which leads to a decrease in the production of new copies of the virus. This drug has also been shown to have anticancer properties, although it is not currently approved for this use. Stavudine 5'-monophosphate triethylammonium salt is synthesized in high purity and high quality, with a CAS number of 102747-23-2.</p>Pureza:Min. 95%N4-Benzoyl-5'-O-DMT-2'-O-(2-methylacetamido)-5-methylcytidine 3'-CE phosphoramidite
<p>N4-Benzoyl-5'-O-DMT-2'-O-(2-methylacetamido)-5-methylcytidine 3'-CE phosphoramidite is a novel, antiviral, and anticancer agent. It has high purity and quality, and is modified with an acetyl group (N4-benzoyl) at the 5' position of the nucleotide sugar. This product has a CAS No. of 636371-27-0 and may be used as a monophosphate or diphosphate. The N4-benzoyl group is not present in natural nucleosides; therefore, this analog can serve as an activator for ribonucleoside kinase by mimicking the natural substrate.</p>Pureza:Min. 95%2'-O-tert-Butyldimethylsilyl-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite is a nucleoside monophosphate with CAS No. 58822-52-3. It is an activator that has anticancer and antiviral properties. This product is modified, novel and high purity and quality. 2'-O-tert-Butyldimethylsilyl-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite can be used in the synthesis of oligonucleotides for use as probes or drugs in the treatment of cancer, HIV, hepatitis B and influenza A.Fórmula:C49H67N8O8PSiPureza:Min. 95%Peso molecular:955.19 g/molDisodium adenosine 5'-phosphate hydrate
CAS:Disodium adenosine 5'-phosphate hydrate is a novel, modified nucleotide analogue that is used in antiviral therapy. It has been shown to be an effective inhibitor of herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and cytomegalovirus. Disodium adenosine 5'-phosphate hydrate also inhibits DNA polymerase and RNA polymerase, thereby preventing replication of the virus genome. Disodium adenosine 5'-phosphate hydrate has been shown to be active against cancer cells in vitro and in vivo, as well as being useful in the treatment of cancer.Fórmula:C10H14N5Na2O8PPureza:Min. 95%Peso molecular:409.2 g/mol(-)-Adenosine 3'-monophosphate hydrate
CAS:<p>Adenosine 3'-monophosphate hydrate is a nucleoside that is an important intermediate in the biosynthesis of DNA and RNA. It is a phosphodiesterase inhibitor, which prevents the breakdown of adenosine 3'-monophosphate (cAMP). This compound also has a role in various other metabolic pathways, such as the synthesis of purines. Adenosine 3'-monophosphate hydrate is used for preparing adenosylcobalamin and for studies on phosphodiesterases. The nature of this compound is determined by its chemical structure, including functional groups and sequences. Its modification includes the addition of phosphate groups to its ribose sugar moiety. Adenosine 3'-monophosphate hydrate has a molecular weight of 372.4 g/mol and optimum pH of 7-8.<br>The hybridization behavior and ph optimum are characteristic properties of this compound.</p>Fórmula:C10H16N5O8PPureza:Min. 95%Peso molecular:365.24 g/mol2-Chloro-4-hydroxy-5-fluoropyrimidine
CAS:2-Chloro-4-hydroxy-5-fluoropyrimidine is a nucleoside with antiviral and anticancer activity. It has shown to be an effective agent against HIV, herpes virus and human papilloma virus. 2-Chloro-4-hydroxy-5-fluoropyrimidine inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase, which catalyzes the formation of diphosphate from monophosphate. In addition, it inhibits protein synthesis by inhibiting ribonucleotide reductase, which catalyzes the conversion of ribonucleotides to deoxyribonucleotides.Fórmula:C4H2ClFN2OPureza:Min. 95%Peso molecular:148.52 g/mol5-Fluoro-1-(b-L-ribofuranosyl)-uracil
CAS:<p>5-Fluoro-1-(b-L-ribofuranosyl)-uracil is a triflate that is synthesized by the intramolecular, stereospecific reaction of l-guanosine and l-adenosine. It has been shown to have high yields in its synthesis. 5-Fluoro-1-(b-L-ribofuranosyl)-uracil can be used to produce glycosidations with d-galactose and l-thymidine. This product can also be used for the production of l-[5-(2,4,6-trimethoxybenzoyl)-1Hpyrazol]-3-[(2S,3R)-3-(bromomethyl)pyrrolidin]-2one (PBI), which is an inhibitor of protein kinase C.</p>Pureza:Min. 95%2,2'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine
2,2'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine is a novel monophosphate nucleoside analog that has antiviral activity against herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2). This compound is chemically synthesized by the reaction between thymidine with bis-(2,6-diisopropylphenyl) disilazane in the presence of an activator. The synthesis of 2,2'-anhydro-5'-O-tert-butyldiphenylsilylthymidine is performed by reacting 5'-O-(4,4'-dimethoxytrityl)-thymidine with bis-(2,6-diisopropylphenyl) disilazane in the presence of tetrakis(triphenylphosphine)palladium(0Pureza:Min. 95%N2-Isobutyryl-7’-tert-butyldimethylsilyl-N-trityl-morpholino guanosine
N2-Isobutyryl-7’-tert-butyldimethylsilyl-N-trityl-morpholino guanosine is a modified nucleoside that can be used in the synthesis of DNA, RNA, and other nucleic acids. It is a novel monophosphate that has been shown to have anticancer and antiviral properties. N2-Isobutyryl-7’-tert-butyldimethylsilyl-N-trityl-morpholino guanosine is synthesized by reacting 2,4,6 trichlorobenzoyl chloride with morpholine and silylation. This product has high purity and quality as it is made synthetically from high quality materials.Pureza:Min. 95%3'-Deoxy-L-thymidine
CAS:<p>3'-Deoxy-L-thymidine is a nucleoside analog that inhibits HIV replication by interfering with the synthesis of viral DNA. The drug binds to the enzyme thymidine phosphorylase, which converts thymidine into deoxyuridine monophosphate, and prevents conversion of deoxyuridine to deoxythymidine monophosphate. This leads to inhibition of both DNA synthesis and the production of RNA. 3'-Deoxy-L-thymidine has dose-limiting toxicity at high doses and is not active against other viruses such as herpes simplex virus or cytomegalovirus. It is metabolized in the liver by enzymes such as 5-fluorocytosine, which converts it into its active form, 5-fluorouracil.</p>Fórmula:C10H14N2O4Pureza:Min. 95%Peso molecular:226.23 g/mol5,6-Dihydrothymidine
CAS:<p>5,6-Dihydrothymidine is a hydroxylated thymidine analogue. It binds to the leukocyte antigen, which is found on many different types of cells. 5,6-Dihydrothymidine inhibits the replication of herpes simplex virus and can be used for diagnostic purposes. 5,6-Dihydrothymidine has been shown to have conformational properties that are similar to those of thymine, which allows it to bind to the template strand in DNA. This binding prevents the synthesis of messenger RNA from DNA. 5,6-Dihydrothymidine is also able to inhibit cell growth in culture and can be used as a cell culture medium supplement.</p>Fórmula:C10H16N2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:244.24 g/mol
