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Nucleosídeos

Nucleosídeos

Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.

Foram encontrados 3569 produtos de "Nucleosídeos"

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  • Thymidine 5'- triphosphate lithium salt - 100mM aqueous solution

    CAS:
    Thymidine 5’-triphosphate tetralithium salt (dTTP) is a crucial component in chemical biology research. It is a modified form of thymidine, containing three phosphate groups. Important in DNA replication and repair, dTTP acts as a substrate for DNA polymerases during polymerase chain reactions (PCR), facilitating the amplification of specific DNA sequences. In addition, in DNA sequencing, dTTP is incorporated into newly synthesized DNA strands, allowing precise determination of nucleotide sequences.
    Fórmula:C10H17N2O14P3·xLi
    Pureza:Min. 95%
    Peso molecular:482.17 g/mol

    Ref: 3D-ND46293

    40mg
    303,00€
  • 6-Bromo-4-chloropyrido[2,3-d]pyrimidine

    CAS:
    6-Bromo-4-chloropyrido[2,3-d]pyrimidine is a pyrimidine derivative that has been synthesized using cyclization and condensation techniques. The synthesis of this compound is efficient and uses relatively low amounts of starting materials. It can be made using microwave irradiation in a high yield. 6-Bromo-4-chloropyrido[2,3-d]pyrimidine is an aromatic ring with efficient methods for synthesis and bromination. This research could be used to produce new compounds with similar structures that are more potent than current drugs.
    Pureza:Min. 95%

    Ref: 3D-NB44335

    1g
    860,00€
    100mg
    303,00€
    250mg
    473,00€
    500mg
    633,00€
  • 8-Chloroadenosine 3',5'-cyclic monophosphate

    CAS:
    8-Chloroadenosine 3',5'-cyclic monophosphate (8-CAM) is a potent inducer of the mitochondrial membrane potential. It has been shown to have cytotoxic effects on human myeloma cell line, HL-60 cells, and fetal bovine serum. 8-CAM has shown anticancer properties in solid tumours in mice. It was also found to be toxic to human carcinoma cell lines and synergistic with other pharmacological agents, such as doxorubicin. 8-CAM has been shown to have immunosuppressive effects in animal models and may be a potential therapeutic agent for autoimmune diseases.
    Fórmula:C10H11ClN5O6P
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:363.65 g/mol

    Ref: 3D-NC10380

    1mg
    286,00€
    2mg
    430,00€
    5mg
    717,00€
    10mg
    1.019,00€
  • 6-Methyl-3-(β-D-2-ribofuranosyl)pyrrolo[2,3-d]pyrimidin-2-one

    CAS:
    6-Methyl-3-(β-D-2-ribofuranosyl)pyrrolo[2,3-d]pyrimidin-2-one is a synthetic nucleoside that has been shown to have potent antitumor activity in leukemia. It inhibits the synthesis of DNA by chemically binding to the enzyme that catalyzes the formation of pyrimidine nucleosides from uridine, thereby preventing RNA and DNA synthesis. 6-Methyl-3-(β-D-2-ribofuranosyl)pyrrolo[2,3-d]pyrimidin-2-one also reversibly binds to the template strand of dna and prevents replication. This drug is effective in treating chronic lymphocytic leukemia (CLL).
    Fórmula:C12H15N3O5
    Pureza:Min. 95%
    Peso molecular:281.26 g/mol

    Ref: 3D-UAB96284

    100mg
    894,00€
  • 3'-O-Azidomethyl 2'-deoxyguanosine 5'-O-triphosphate sodium salt


    3'-O-Azidomethyl 2'-deoxyguanosine 5'-O-triphosphate sodium salt is an antiviral and anticancer agent used in the treatment of HIV, hepatitis B, hepatitis C, herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, cytomegalovirus, Epstein-Barr virus, and Kaposi's sarcoma. It is a nucleotide analog that inhibits viral replication by inhibiting DNA synthesis. The phosphate group on this compound is modified with an azide group to inhibit deamination by phosphodiesterases. This product has been shown to be effective against leukemia cells.
    Pureza:Min. 95%

    Ref: 3D-NA46070

    1mg
    1.952,00€
    2mg
    3.660,00€
  • 5-Amino-1-(b-D-ribofuranosyl)imidazole-4-carboxamide-5'-phosphate


    5-Amino-1-(b-D-ribofuranosyl)imidazole-4-carboxamide-5'-phosphate is a ribonucleoside monophosphate. It is an antiviral agent that inhibits the synthesis of RNA by preventing the attachment of ribonucleotides to the 5' end of RNA. This drug is also used in anticancer therapy, as it has been shown to inhibit DNA synthesis and induce cell differentiation. 5-Amino-1-(b-D-ribofuranosyl)imidazole-4-carboxamide-5'-phosphate is synthesized from 1-(2'-deoxyribofuranosyl)-5-(2'-deoxyribofuranosyl)imidazole, which can be made from 2,4,6,-triaminopyrimidine and 2,3,-dideoxyribose. This product has CAS number 13
    Pureza:Min. 95%

    Ref: 3D-NA158845

    100mg
    303,00€
    250mg
    336,00€
  • 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinocytidine

    CAS:
    3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinocytidine is a modified nucleoside that is used as an anticancer agent. This active form has been shown to have antiviral and antitumor activities. The drug is synthesized by reacting 2,4,6-trihydroxybenzoic acid with 2'-deoxyribose and then 2'-fluoroarabinonucleotidase. 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinocytidine has high purity and high quality, which makes it suitable for use in the synthesis of phosphoramidites.
    Pureza:Min. 95%

    Ref: 3D-ND144470

    100mg
    303,00€
    250mg
    454,00€
  • N6-Benzoyl-5'-O-DMT-2'-O-(2-Ethoxy-2-oxoethyl)adenosine


    N6-Benzoyl-5'-O-DMT-2'-O-(2-Ethoxy-2-oxoethyl)adenosine is a phosphoramidite that is used in the synthesis of oligonucleotides. It is an activator of ribonucleotides and diphosphate for RNA synthesis. Its high purity and quality make it suitable for use in the synthesis of DNA, RNA, or other nucleoside analogues.
    Pureza:Min. 95%

    Ref: 3D-NB158849

    25mg
    303,00€
    50mg
    336,00€
  • 3',5'-Di-O-benzoyl-5-fluoro-2'-O-methyluridine

    CAS:
    3',5'-Di-O-benzoyl-5-fluoro-2'-O-methyluridine is a nucleoside that acts as an activator and phosphoramidite. The di-O-benzoyl group is used to protect the 2'-hydroxyl group during the synthesis of oligonucleotides. 3',5'-Di-O-benzoyl-5-fluoro-2'-O-methyluridine has been shown to have anticancer activity against human breast cancer cells. It also inhibits the replication of DNA viruses, such as HIV, hepatitis B virus and herpes simplex virus type 1, and is active against influenza A virus. This compound has also been shown to inhibit the production of inflammatory cytokines in vitro.
    Fórmula:C24H21FN2O8
    Pureza:Min. 95%
    Peso molecular:484.44 g/mol

    Ref: 3D-ND06453

    1g
    741,00€
    100mg
    303,00€
    250mg
    318,00€
    500mg
    470,00€
  • 2'-Deoxy-5'-O-DMT-uridine succinyl 3'-CPG


    <p>2'-Deoxy-5'-O-DMT-uridine succinyl 3'-CPG is a novel, synthetic, high purity, and high quality activator for oligonucleotide synthesis. It is a modified nucleoside with a 2' -deoxy-5'-O-dimethoxytrityl group attached to the sugar moiety. This product is used in monophosphate form and can be used as an anticancer agent. This product has antiviral activity, which may be due to its ability to inhibit viral DNA and RNA synthesis.</p>
    Pureza:Min. 95%

    Ref: 3D-ND11634

    1g
    838,00€
    2g
    1.259,00€
    100mg
    303,00€
    250mg
    376,00€
    500mg
    514,00€
  • 5'-O-DMT-2'-O-(2-methylacetamido)-5-methyluridine 3'-CE phosphoramidite


    <p>5'-O-DMT-2'-O-(2-methylacetamido)-5-methyluridine 3'-CE phosphoramidite is a high purity, diphosphate, Anticancer, Modified, Phosphoramidites, DNA, High quality, Novel, Activator. It is CAS No. 106433-85-6 and has the molecular formula C15H14N4O8P. 5'-O-DMT-2'-O-(2-methylacetamido)-5-methyluridine 3'-CE phosphoramidite is not found in nature. This product is a monophosphate nucleoside that belongs to the group of nucleosides and deoxyribonucleosides. It can be used for synthesis of DNA and RNA, as well as for the treatment of cancer cells.</p>
    Pureza:Min. 95%

    Ref: 3D-PD167503

    100mg
    303,00€
  • NPOM-Caged-dT CEP

    CAS:
    <p>Please enquire for more information about NPOM-Caged-dT CEP including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C50H58N5O13P
    Pureza:Min. 95%
    Peso molecular:968 g/mol

    Ref: 3D-SMB21871

    250mg
    708,00€
    500mg
    1.014,00€
  • Adenine

    CAS:
    Adenine is a purine nucleoside that has guanine as its base. It has the chemical formula C5H5N5O and can be found in RNA, DNA, and ATP. Adenine is an important component of the human body because it is a key component of nucleic acids. It also plays a role in the regulation of metabolism and the production of energy. Adenine is one of the most abundant molecules in cells, making up 75% of DNA and 50% of RNA. Adenine is biosynthesized from aspartic acid by removing an amino group on aspartate to form oxaloacetate, which reacts with glyoxylate to form citric acid. This reaction requires vitamin B6 to function properly. The optimum concentration for adenine is between 10-100 mM, but it can be toxic at high concentrations (greater than 1 M). Adenine binds to sulfa drugs through hydrogen bonding interactions and also inhibits the enzyme x
    Fórmula:C5H5N5
    Pureza:Min. 98.0 Area-%
    Peso molecular:135.13 g/mol

    Ref: 3D-Q-200596

    1kg
    A consultar
    5kg
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    10kg
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    25kg
    A consultar
    2500g
    A consultar
    -Unit-kgkg
    A consultar
  • 5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite


    5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite is a high purity, modified nucleoside with anticancer potential. It is an activator of DNA synthesis and inhibits the growth of tumor cells. This chemical is a monophosphate or diphosphate, depending on the conditions used in synthesis. 5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite is used to synthesize DNA, RNA, and deoxyribonucleosides. It is also used as a precursor for other ribonucleosides and nucleotides that are needed in the synthesis of DNA and RNA. 5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite can be synthesized from commercially available starting materials such as 4-(2-deoxyribofuranosyl)thymidine, 5-(3,
    Fórmula:C41H51N4O8P
    Pureza:Min. 95%
    Peso molecular:758.86 g/mol

    Ref: 3D-PD09186

    250mg
    666,00€
  • 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-Me phosphoramidite


    2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-Me phosphoramidite is a novel nucleoside analog with antiviral and anticancer activities. It inhibits viral replication by inhibiting the viral polymerase and cellular DNA polymerases. 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-Me phosphoramidite also inhibits tumor growth by arresting cells in the G2/M phase of the cell cycle. This compound has been shown to be effective against human leukemia, lymphoma, breast cancer, and colon cancer cells.
    Fórmula:C46H53N6O8P
    Pureza:Min. 95%
    Cor e Forma:Solid
    Peso molecular:848.94 g/mol

    Ref: 3D-PD09151

    1g
    329,00€
    500mg
    300,00€
  • 3,4-Dihydro-3-oxo-4-b-D-ribofuranosyl-2-pyrazinecarboxamide

    CAS:
    3,4-dihydro-3-oxo-4-(2-pyrimidinyl)-2,5-dioxopyrrolidine carboxamide is an analog of acyclovir that has antiviral activity against a variety of viruses. It binds to the receptor binding site on the virus and prevents viral replication. 3,4-Dihydro-3-oxo-4-(2-pyrimidinyl)-2,5-dioxopyrrolidine carboxamide is effective against human influenza A virus (H1N1) and hepatitis B virus. This drug also has been shown to inhibit the growth of phlebovirus in cell culture by preventing the synthesis of viral RNA.
    Fórmula:C10H13N3O6
    Pureza:Min. 95%
    Peso molecular:271.23 g/mol

    Ref: 3D-ND31834

    1g
    3.021,00€
  • N2-Acetyl-6-[2-(4-nitrophenyl)ethoxy]-2'-O-trifluoromethanesulfonyl-3',5'-di-O-tritylguanosine


    N2-Acetyl-6-[2-(4-nitrophenyl)ethoxy]-2'-O-trifluoromethanesulfonyl-3',5'-di-O-tritylguanosine is a novel nucleotide that is activated by the addition of 2'-deoxyribonucleosides and has antiviral activity. It was synthesized from 2'-deoxynucleoside 5'-triphosphates and 4,4'-dimethoxytrityl chloride in high yield. The compound is also shown to have anticancer activity against human leukemia cells and breast cancer cells.
    Pureza:Min. 95%

    Ref: 3D-NA34795

    100mg
    A consultar
  • 2-[[4-[2-(tert-Butoxycarbonyl)ethyl]phenylethyl]amino]2',3'-O-isopropylideneadenosine-5'-N-ethylcarboxamide

    CAS:
    2-[[4-[2-(tert-Butoxycarbonyl)ethyl]phenylethyl]amino]2',3'-O-isopropylideneadenosine-5'-N-ethylcarboxamide is a novel nucleoside that inhibits DNA synthesis and viral replication. It has been shown to be active against the herpes simplex virus type 1, influenza virus, and human immunodeficiency virus. 2-[[4-[2-(tert-Butoxycarbonyl)ethyl]phenylethyl]amino]2',3'-O-isopropylideneadenosine-5'-N-ethylcarboxamide is currently being developed as an anticancer drug. This molecule prevents tumor growth by inhibiting the proliferation of cancer cells.
    Fórmula:C30H41N7O6
    Pureza:Min. 95%
    Peso molecular:595.69 g/mol

    Ref: 3D-NB16642

    10mg
    303,00€
    25mg
    365,00€
    50mg
    592,00€
    100mg
    1.017,00€
  • 2',3',5'-Tri-O-acetylisoguanosine

    CAS:
    2',3',5'-Tri-O-acetylisoguanosine is a modified nucleoside with anticancer activity. It is a ribonucleoside that is deoxyribonucleosides, and it has been shown to be an activator of the diphosphate moiety in the enzyme DNA polymerase. This novel compound has antiviral and antibacterial properties, as well as anti-inflammatory activities. 2',3',5'-Tri-O-acetylisoguanosine (TAI) is also used as a monophosphate donor in phosphoramidite coupling reactions.
    Fórmula:C16H19N5O8
    Pureza:Min. 95%
    Peso molecular:409.35 g/mol

    Ref: 3D-NT07233

    50mg
    303,00€
    100mg
    416,00€
  • 7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine

    CAS:
    7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a diphosphate nucleoside analogue that can be activated by phosphoramidites. It is a novel, synthetic, and high quality nucleotide with antiviral and anticancer properties. This drug has been shown to inhibit the synthesis of DNA and RNA at the transcriptional level. 7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a monophosphate nucleoside analogue that can be used in ribonucleotide synthesis for the treatment of cancer.
    Fórmula:C16H16F3N5O3
    Peso molecular:383.33 g/mol

    Ref: 3D-J-700297

    1g
    A consultar
    50mg
    A consultar
    100mg
    A consultar
    250mg
    A consultar
    500mg
    A consultar
    -Unit-gg
    A consultar
  • 5'-Azido-5'-deoxy-2',3'-O-isopropylideneadenosine

    CAS:
    5'-Azido-5'-deoxy-2',3'-O-isopropylideneadenosine (5ADeA) is a novel nucleoside with antiretroviral and antitumor activity. It is an activator of the innate immune system, which stimulates the production of cytokines such as TNF-α and IL-1β. This agent also inhibits viral replication by inhibiting viral RNA synthesis through its effect on the enzyme ribonucleotide reductase. 5ADeA monophosphate has been shown to be an effective antiviral against HIV and hepatitis C virus, as well as being active against human papilloma virus and Epstein-Barr virus. 5ADeA is synthesized in high purity and has a CAS number of 34245-48-2.
    Fórmula:C13H16N8O3
    Pureza:Min. 95%
    Peso molecular:332.32 g/mol

    Ref: 3D-NA46265

    1g
    3.050,00€
  • 5'-O-(4,4'-Dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl)thymidine 3'-CE phosphoramidite

    Produto Controlado
    CAS:
    5'-O-(4,4'-Dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl)thymidine 3'-CE phosphoramidite is a novel nucleoside with antiviral activity. It is synthesized through the condensation of 5-bromo-2′-deoxyuridine and 4,4′-dimethoxytrityl chloride. This compound has been shown to inhibit the synthesis of DNA and RNA in vitro. It also has anticancer properties and can be used for the treatment of leukemia.
    Fórmula:C50H52F17N4O9P
    Pureza:Min. 95%
    Peso molecular:1,206.92 g/mol

    Ref: 3D-PD11331

    250mg
    304,00€
    500mg
    423,00€
  • 2'-Deoxy-5-iodouridine-5'-triphosphate sodium salt - 10mM aqueous solution

    CAS:
    2'-Deoxy-5-iodouridine-5'-triphosphate sodium salt is a potent inhibitor of thymidylate synthase, an enzyme that catalyzes the conversion of deoxyuridine to thymidylate. 2'-Deoxy-5-iodouridine-5'-triphosphate sodium salt has been found to have a noncompetitive inhibition effect on bacterial DNA replication and is used as a chemotherapeutic agent in the treatment of cancer. It is also used as a radioprotectant during radiation therapy. The optimum concentration for 2'-deoxy-5-iodouridine-5'-triphosphate sodium salt is 10mM, which inhibits bacterial enzymes but does not inhibit mammalian enzymes.
    Fórmula:C9H10N2O14P3I·4Na
    Pureza:Min. 95%
    Peso molecular:681.97 g/mol

    Ref: 3D-ND31484

    1g
    2.442,00€
    1mg
    491,00€
    2500µg
    831,00€
  • N2-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-deoxy-b-D-ribofuranosyl)purine


    N2-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-deoxy-b-D-ribofuranosyl)purine is a phosphoramidite that is used as a precursor for the synthesis of modified oligonucleotides. It is also active against cancer and antiviral pathogens. N2-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-deoxy-b-D ribofuranosyl)purine has been shown to inhibit viral replication in vitro by inhibiting the formation of viral DNA, RNA, and protein. This drug has been shown to inhibit the growth of mouse leukemia cells in vivo. It also inhibits DNA synthesis by binding to the enzyme DNA polymerase, which is required for replication of bacterial and viral DNA.
    Fórmula:C38H35N5O6
    Pureza:Min. 95%
    Peso molecular:657.71 g/mol

    Ref: 3D-NB08322

    1g
    1.718,00€
    50mg
    303,00€
    100mg
    415,00€
    250mg
    589,00€
    500mg
    979,00€
  • 5'-O-DMT-5-methyl-(2'-O-4'-C-methylene)-uridine 3'-CE-phosphoramidite


    5'-O-DMT-5-methyl-(2'-O-4'-C-methylene)-uridine 3'-CE-phosphoramidite is a nucleoside phosphoramidite and an anticancer drug. It is a modified nucleoside that has been synthesized by the chemical reaction of 5'-O-dimethoxytritylthymidine with 5'-O-DMT-5-methyl-(2'-O-4'-C-methylene)uridine 3' chloroformate. 5'-O-DMT-5-methyl-(2'-O-4' -C methylene)-uridine 3' chloroformate is synthesized in three steps starting from 1,3,5,7,9,11,13,15,-hexahydrobenzo[a]pyrrolo[1,'c']azepin 2(3H)-one.
    Pureza:Min. 95%

    Ref: 3D-PD11643

    1g
    974,00€
    250mg
    413,00€
    500mg
    592,00€
  • 2'-Deoxyuridine-5'-[(a,b)-imido]diphosphate sodium salt - 10mM aqueous solution

    CAS:
    2'-Deoxyuridine-5'-[(a,b)-imido]diphosphate sodium salt - 10mM aqueous solution is an organic compound that is used as a plant growth regulator. It inhibits the activity of plant enzymes, such as adenylate cyclase and protein kinase C, thereby blocking the production of proteins in plants. 2'-Deoxyuridine-5'-[(a,b)-imido]diphosphate sodium salt - 10mM aqueous solution has been shown to be toxic to muscle tissue and can cause acute toxicity in mammals. However, it has been found to be safe for use on plants when diluted with water.
    Fórmula:C9H15N3O10P2
    Pureza:Min. 95%
    Peso molecular:387.18 g/mol

    Ref: 3D-ND45195

    1mg
    561,00€
    2mg
    784,00€
  • antisense


    Antisense is a type of experimental therapy that uses a single-stranded RNA molecule to bind to complementary RNA molecules, blocking their function. Antisense rna is often used in gene regulation and chromatin remodeling. It also regulates the transcription of mRNA by binding to the messenger RNA molecule as it leaves the nucleus. The main output of antisense is an increase in the production of one type of protein or a decrease in another. Antisense has been shown to be effective in regulating gene expression and can be used to treat diseases such as cancer and autoimmune disorders.
    Pureza:Min. 95%

    Ref: 3D-NA11588

    1g
    2.440,00€
  • 2',3'-Dideoxyuridine-5'-O-monothiophosphate

    CAS:
    2',3'-Dideoxyuridine-5'-O-monothiophosphate is an antiviral nucleoside that inhibits viral DNA synthesis. It is a phosphoramidate prodrug of the natural compound deoxyuridine monophosphate (dUMP). 2',3'-Dideoxyuridine-5'-O-monothiophosphate has been shown to be active against human papilloma virus and to inhibit the replication of some DNA viruses, including herpes simplex virus, cytomegalovirus, and Epstein-Barr Virus. This drug has also been shown to have anticancer activity in vitro and in vivo.
    Fórmula:C9H13N2O6PS
    Pureza:Min. 95%
    Peso molecular:308.25 g/mol

    Ref: 3D-ND10394

    1µg
    303,00€
    5µg
    497,00€
    10µg
    736,00€
  • a-Nicotinamide adenine dinucleotide phosphate

    CAS:
    a-Nicotinamide adenine dinucleotide phosphate (NADP) is a modified form of the natural coenzyme nicotinamide adenine dinucleotide (NAD) and is an important component in cellular metabolism. NADP is also an anticancer agent that inhibits the synthesis of DNA, RNA, and protein. It is used for the treatment of viral infections such as cytomegalovirus (CMV), herpes simplex virus (HSV), varicella zoster virus (VZV), and Epstein-Barr virus (EBV). NADP is also a novel antiviral agent that has been shown to inhibit the enzyme diphosphate kinase, which prevents the production of ATP. This inhibition leads to cell death by disrupting normal energy production. NADP has been shown to be effective against CMV isolates resistant to ganciclovir or foscarnet due to its ability to inhibit DNA synthesis.
    Fórmula:C21H28N7O17P3
    Pureza:Min. 95%
    Peso molecular:743.41 g/mol

    Ref: 3D-NN29116

    1g
    2.440,00€
  • 4-(4-Bromophenyl)pyrimidine-2-thiol

    CAS:
    The dynamical module is a polluting, herbaceous, high pressure system. It has the following characteristics:
    Fórmula:C10H7BrN2S
    Pureza:Min. 95%
    Peso molecular:267.15 g/mol

    Ref: 3D-NB57410

    1g
    526,00€
    2g
    793,00€
    5g
    1.174,00€
    500mg
    300,00€
  • Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt

    CAS:
    Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt is a neurotrophic factor that has been shown to have neuroprotective properties in different animal models of Parkinson's disease. It has been shown to promote the synthesis of dopamine, glutamate, and other neurotransmitters in dopaminergic neurons. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt also promotes protein production by stimulating the synthesis of intracellular proteins such as cytosolic Ca2+ and IGF-I. This drug may be effective in pharmacological treatment for Parkinson's disease. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt is a potent inhibitor of phosphodiesterase type 4 (PDE4) with a Ki value of 0.07 μM. This inhibition leads to the accumulation of cAMP, which activates protein kinase A (PKA
    Fórmula:C10H11N5O5PS·Na
    Pureza:Min. 95%
    Peso molecular:367.25 g/mol

    Ref: 3D-NA58197

    1mg
    394,00€
    2mg
    547,00€
    5mg
    1.096,00€
    10mg
    1.879,00€
    20mg
    3.050,00€
  • 2-(Propylthio)pyrimidine-5-carbaldehyde

    CAS:
    <p>2-(Propylthio)pyrimidine-5-carbaldehyde (2-PSPCA) is a novel, modified ribonucleoside that has been shown to activate the DNA polymerase. 2-PSPCA has been used in the synthesis of deoxyribonucleosides and phosphoramidites for use in the research and development of antiviral agents and anticancer drugs. 2-PSPCA is a monophosphate with an IC50 of 0.6 mM against human leukemia cells.</p>
    Fórmula:C8H10N2OS
    Pureza:Min. 95%
    Peso molecular:182.24 g/mol

    Ref: 3D-NP57432

    2g
    303,00€
    5g
    328,00€
    10g
    493,00€
    25g
    702,00€
  • 4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1-b-D-ribofuranose

    CAS:
    4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1b-D-ribofuranose is a novel diphosphate activator that can modify the properties of deoxyribonucleosides and nucleosides. It has antiviral activity against human immunodeficiency virus type 1 (HIV) and herpes simplex virus type 2 (HSV). 4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1b -D--ribofuranose is also an anticancer agent that has been shown to have DNA binding ability, in addition to its ability to inhibit the proliferation of cancer cells.
    Fórmula:C17H19N5O4
    Pureza:Min. 95%
    Peso molecular:357.36 g/mol

    Ref: 3D-NA16507

    1mg
    1.209,00€
    2mg
    2.141,00€
    5mg
    3.892,00€
  • 3'-O-Acetyl-5-benzylaminocarbonyl-2'-O-methyl-5'-O-DMT-uridine


    3'-O-Acetyl-5-benzylaminocarbonyl-2'-O-methyl-5'-O-DMT-uridine is a novel, modified nucleoside. This product is an activator of the ribonucleotide reductase enzyme and is used as a precursor in the synthesis of deoxyribonucleosides. It has antiviral activity against herpes simplex virus type 1 and cytomegalovirus. It has also been shown to have anticancer properties, as it inhibits DNA synthesis and tumor cell proliferation without affecting healthy cells. 3'-O-Acetyl-5-benzylaminocarbonyl-2'-O-methyl-5'-O-DMT uridine is synthesized from 5-(3,4,5)-trimethoxybenzaldehyde, 2′(2,6 dichloro)amino]methyl]benzeneacetic acid methyl ester and 5
    Pureza:Min. 95%

    Ref: 3D-NA144580

    3g
    4.574,00€
  • 2',5'-Dideoxy-2'-fluoro-5'-iodouridine

    CAS:
    <p>2',5'-Dideoxy-2'-fluoro-5'-iodouridine is a modified nucleoside that is used in the synthesis of oligonucleotides. It can be used as an antiviral and anticancer agent. The drug has been shown to inhibit the replication of DNA and RNA, which may lead to cell death. 2',5'-Dideoxy-2'-fluoro-5'-iodouridine is also known for its high purity, novel structure and stability.</p>
    Fórmula:C9H10FIN2O4
    Pureza:Min. 95%
    Peso molecular:356.09 g/mol

    Ref: 3D-ND10106

    10mg
    303,00€
    25mg
    336,00€
    50mg
    473,00€
  • 5-Aza-3',5'-di-O-acetyl-2'-deoxycytidine


    5-Aza-3',5'-di-O-acetyl-2'-deoxycytidine is a nucleoside analog that is used in the treatment of HIV. It inhibits viral replication by interfering with the viral reverse transcriptase enzyme and preventing it from transcribing the virus's genetic material. 5-Aza-3',5'-di-O-acetyl-2'-deoxycytidine has also been shown to have anticancer properties. This drug has shown activity against cancer cells in vitro, although clinical trials are still needed to determine its effectiveness as a cancer therapy.
    Fórmula:C12H16N4O6
    Pureza:Min. 95%
    Peso molecular:312.28 g/mol

    Ref: 3D-NA13520

    1g
    1.047,00€
    5g
    3.842,00€
  • Adenosine 5'-difluoromethylene-5'-triphosphate triethylammonium salt


    Adenosine 5'-difluoromethylene-5'-triphosphate triethylammonium salt is a novel nucleotide activator that has antiviral, anticancer, and ribonucleoside activities. This activator is a phosphoramidite monomer with an adenine base. The pharmaceutical industry uses this activator as a starting material in the synthesis of anticancer drugs and antiviral drugs. It is also used as a reagent in the production of modified DNA and RNA molecules for use in gene therapy and drug discovery.
    Pureza:Min. 95%

    Ref: 3D-NA31345

    25mg
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    50mg
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    100mg
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  • 2'-Deoxy-2'-fluoroadenosine-5'-monophosphate

    CAS:
    <p>2'-Deoxy-2'-fluoroadenosine-5'-monophosphate is a nucleotide that is used as an anthelmintic drug. It inhibits the synthesis of fatty acids and ATP levels in tissue culture cells. This nucleotide has also been shown to have immunomodulatory effects, which may be due to its ability to bind to receptor activity. 2'-Deoxy-2'-fluoroadenosine-5'-monophosphate binds with high affinity to the response elements of transcription factors such as NF-κB and AP1, which are involved in the regulation of gene expression and inflammatory responses.</p>
    Fórmula:C10H13FN5O6P
    Pureza:Min. 95%
    Peso molecular:349.21 g/mol

    Ref: 3D-ND145452

    10mg
    2.257,00€
  • 5-Azido- 2'- deoxycytidine

    CAS:
    <p>5-Azido-2'-deoxycytidine is a high purity, novel, modified, and synthesized nucleoside with anticancer and antiviral properties. It is a diphosphate that is used in the synthesis of DNA as an activator. 5-Azido-2'-deoxycytidine has been shown to inhibit the growth of cancer cells and to be active against influenza virus.</p>
    Fórmula:C9H12N6O4
    Pureza:Min. 95%
    Peso molecular:268.23 g/mol

    Ref: 3D-NA167226

    1mg
    303,00€
    5mg
    626,00€
    10mg
    949,00€
  • 2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-E-propenyl]-uridine 3-CE phosphoramidite

    CAS:
    2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-E-propenyl]-uridine 3-CE phosphoramidite is a synthetic nucleoside analog that has been modified to contain a triphosphate group. It is used in the synthesis of DNA or RNA. The compound is synthesized from 2,4-dichloro-N-(2,6-dimethoxybenzyl)phenylamine, which was reacted with ethyl (3-[(trifluoroacetyl)amino]propanoate) and deoxythymidine 3'-monophosphate. The CAS number for this product is 851520-76-8.
    Pureza:Min. 95%

    Ref: 3D-PD138043

    1g
    1.074,00€
    2g
    1.646,00€
    5g
    3.137,00€
    10g
    5.228,00€
  • 2’,5’-Dideoxy-5’-iodouridine

    CAS:
    <p>2’,5’-Dideoxy-5’-iodouridine is an antiviral drug that inhibits DNA synthesis. It is a modified nucleoside analog with a phosphoramidite derivative of the natural ribonucleosides and deoxyribonucleosides. This drug is synthesized through the reaction of 2’,5’-dideoxyadenosine with 5-iodo-2-deoxyuridine in the presence of a strong base such as sodium hydride. The resulting product has a high purity, high yield, and can be used for the synthesis of DNA. 2’,5’-Dideoxy-5’-iodouridine also has anticancer properties and has been shown to inhibit cell growth in vitro at concentrations ranging from 0.1 to 1 μM.</p>
    Pureza:Min. 95%

    Ref: 3D-ND163032

    1g
    1.023,00€
    2g
    1.203,00€
    5g
    1.879,00€
  • 5'-O-DMT-thymidine phosphoramidite dimer


    5'-O-DMT-thymidine phosphoramidite dimer is a novel, synthetic nucleoside that can be used for the treatment of cancers. It is an antiviral and antibacterial agent that has been shown to have cytotoxic effects against cancer cells. 5'-O-DMT-thymidine phosphoramidite dimer is not active against bacteria or viruses that are resistant to other nucleoside analogues. This compound inhibits DNA synthesis by inhibiting the activity of DNA polymerase, which is required for the replication of DNA. The chemical structure of 5'-O-DMT-thymidine phosphoramidite dimer resembles thymidine monophosphate, but it has a different sugar group at the 5' position and contains two phosphate groups at the 3' position.
    Pureza:Min. 95%

    Ref: 3D-PD145904

    100mg
    303,00€
    250mg
    457,00€
    500mg
    798,00€
  • 3'-Deoxy-5'-O-trityluridine

    CAS:
    <p>3'-Deoxy-5'-O-trityluridine is a nucleoside that is structurally related to uridine. It belongs to the class of nucleosides and has a hydroxyl group at the 3' position. The 5' position is modified by an anion (most often trityl) sterically, which prevents hydrolysis by esterases or phosphatases. The efficiency of this modification can be increased by using diethyl phosphate as the protecting agent. This modification also provides protection against nucleophiles, such as hydroxyl groups in nucleosides or phosphite triester derivatives. 3'-Deoxy-5'-O-trityluridine is used in the synthesis of other nucleosides and as a substrate for diffraction experiments.</p>
    Fórmula:C28H26N2O5
    Pureza:Min. 95%
    Peso molecular:470.53 g/mol

    Ref: 3D-ND05370

    25mg
    303,00€
    50mg
    365,00€
  • N2-Benzoyl-2'-deoxy-5'-O-DMT-guanosine

    CAS:
    N2-Benzoyl-2'-deoxy-5'-O-DMT-guanosine is a novel and potent anticancer nucleoside with antiviral activity. It is an analog of 2'-deoxy-5'-O-DMT guanosine, which was reported to be the first phosphoramidite nucleoside. N2-Benzoyl-2'-deoxy-5'-O-DMT-guanosine is an excellent candidate for DNA synthesis and has been shown to inhibit viral replication. This product is also of high purity and high quality, and can be used in research applications.
    Fórmula:C38H35N5O7
    Pureza:Min. 95%
    Peso molecular:673.71 g/mol

    Ref: 3D-NB01948

    10g
    3.660,00€
  • 5-Fluorescein dT phosphoramidite


    5-Fluorescein dT phosphoramidite is a novel modified nucleoside that has antiviral, activator, and anticancer properties. It is an analog of fluorouracil with a 5-fluorescein group at the 5' position. This phosphoramidite is synthesized from 2',3'-dideoxyuridine 5'-triphosphate and fluorescein diphosphate. It can be used to bind to DNA and inhibit viral replication. Other anticancer effects may be due to its ability to activate DNA synthesis by binding to deoxyribonucleosides or ribonucleosides in DNA. 5-Fluorescein dT phosphoramidite has high purity and quality, making it suitable for use in nucleotide sequencing, mutagenesis studies, and other applications requiring high purity nucleosides.
    Pureza:Min. 95%

    Ref: 3D-PF05224

    1g
    2.379,00€
    2g
    4.635,00€
  • 5'-O-DMT-thymidine-3'-succinyl CPG 1400 Å


    5'-O-DMT-thymidine-3'-succinyl CPG 1400 Å is a nucleoside analog that has been shown to be an effective anticancer agent. It has been shown to activate the cellular DNA synthesis by stimulating the phosphorylation of RNA polymerase II, which is involved in the transcription of DNA. 5'-O-DMT-thymidine-3'-succinyl CPG 1400 Å also inhibits viral replication and may be effective against AIDS. This nucleoside analog induces antiviral effects by inhibiting the synthesis of viral dsDNA.
    Pureza:Min. 95%

    Ref: 3D-ND11604

    1g
    303,00€
    5g
    497,00€
    10g
    736,00€
  • 5'-Deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine

    CAS:
    5'-Deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine is a modified nucleoside analog that inhibits the growth of viruses. It has been shown to be active against herpes simplex virus type 1 and 2, varicella zoster virus, cytomegalovirus, and Epstein-Barr virus. This drug is used as an antiviral medication in the treatment of viral infections.
    Fórmula:C24H26N4O4
    Pureza:Min. 95%
    Peso molecular:434.5 g/mol

    Ref: 3D-UJB35530

    5g
    1.227,00€
    10g
    1.600,00€
  • 2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-O-succinate triethylammonium salt


    <p>2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-O-succinate triethylammonium salt is a nucleoside that is modified with a 2,2,2-trifluoroethoxycarbonyl group on the 5' position of the sugar moiety. It is an activator for phosphoramidites in DNA synthesis and has been shown to have anticancer activity. It is also used as an antiviral agent and to treat HIV and herpes virus infections. This compound has a molecular weight of 439.5 g/mol and its CAS number is 62273-03-3.</p>
    Fórmula:C34H32FN2O10·C6H16N
    Pureza:Min. 95%
    Cor e Forma:Solid
    Peso molecular:749.84 g/mol

    Ref: 3D-ND10842

    1g
    598,00€
    250mg
    304,00€
    500mg
    416,00€
  • 2'-Deoxyxanthosine ce-phosphoramidite (dx ce-phosphoramidite)

    CAS:
    <p>Please enquire for more information about 2'-Deoxyxanthosine ce-phosphoramidite (dx ce-phosphoramidite) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C56H61N8O12P
    Pureza:Min. 95%
    Peso molecular:1,069.1 g/mol

    Ref: 3D-SLA05043

    250mg
    954,00€
    500mg
    1.248,00€
  • 2'-Deoxyadenosine 5'-a-thiotriphosphate sodium salt


    2'-Deoxyadenosine 5'-a-thiotriphosphate sodium salt is an antiviral nucleotide analog that has been modified to have a novel structure. It is phosphorylated in vivo to form 2'-deoxyadenosine 5'-a-thiotriphosphate. The nucleoside can inhibit viral DNA synthesis and help prevent the spread of HIV, herpes virus type I, herpes virus type II, influenza virus, and other viruses. This compound also has anticancer activity and has been shown to be effective against leukemia cells.
    Pureza:Min. 95%

    Ref: 3D-ND164930

    5mg
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