Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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2,6-Dichloro-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-a-D-arabinofuranosyl)purine
2,6-Dichloro-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-a-D-arabinofuranosyl)purine is a nucleoside that is used in the synthesis of antiviral drugs. It is a modified monophosphate with a 3',5'-di-O-benzoyl group and 2'-deoxyribose. This substance can be prepared from the corresponding 2,6-dichloropurine by reaction with chloroacetaldehyde diethyl acetal. 2,6 Dichloro 9-(3',5'-di-O-benzoyl) purine has been shown to have anticancer activity against various human cancer cell lines in vitro and in vivo.Pureza:Min. 95%1,5-Anhydro-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol
1,5-Anhydro-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol is a novel, activator ribonucleosides deoxyribonucleosides diphosphate phosphoramidites modified anticancer antiviral monophosphate nucleosides synthetic high purity CAS No. It has been shown to have anticancer and antiviral properties. This compound also inhibits the replication of HIV in vitro.Fórmula:C15H21N5O5Pureza:Min. 95%Peso molecular:351.37 g/mol2',3'-Stannyluridine
2',3'-Stannyluridine is a novel modified ribonucleoside. It is synthesized by the condensation of 2'-deoxyuridine and 3'-hydroxy-2-methylpropiophenone. This product has been shown to have anticancer and antiviral activities. 2',3'-Stannyluridine inhibits the synthesis of DNA, RNA, and protein in cells by binding to the ribonucleotide reductase enzyme. It also has an effect on phosphoramidite synthesis, which is an important step in DNA replication. The CAS number for this product is 57824-03-1.
Pureza:Min. 95%3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine
3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine (Zidovudine) is a nucleoside analog that inhibits the replication of human immunodeficiency virus type 1. It is phosphorylated by cellular enzymes to form the active triphosphate form, which incorporates into viral DNA and causes chain termination. Zidovudine has been used in the treatment of HIV infection and AIDS. This drug also has antiviral activity against other retroviruses such as HIV type 2 and measles virus, as well as some DNA viruses, such as herpes simplex type 1. Zidovudine may be useful for the treatment of cancer, particularly Kaposi's sarcoma.Pureza:Min. 95%6-Propylamino-7-deazapurine
CAS:6-Propylamino-7-deazapurine is a synthetic nucleoside with antiviral and anticancer properties. It is an activator of DNA synthesis and is modified to have a high quality. 6-Propylamino-7-deazapurine has been shown to be effective against HIV and other viruses in vitro, as well as in animal models, but it is not yet approved for use in humans.6-Propylamino-7-deazapurine has also been shown to inhibit the growth of cancer cells in vitro and in vivo.
Fórmula:C9H12N4Pureza:Min. 95%Peso molecular:176.22 g/mol3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine
CAS:3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine is a novel antiviral agent that has been synthesized as a high quality, high purity monophosphate. It is a modified nucleoside that is used to synthesize phosphoramidites. It has antiviral activity against herpes simplex virus type 1 and 2, and cytomegalovirus. 3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine is also an inhibitor of the DNA polymerase enzyme and inhibits the synthesis of viral DNA in infected cells. This drug can be used for the treatment of infections caused by these viruses.Fórmula:C13H14BrFN2O7Pureza:Min. 95%Peso molecular:409.16 g/mol2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde
CAS:2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde is a Ribonucleside, Deoxyribonucleoside, Activator, Antiviral, Synthetic and Modified DNA Nucleoside. It has been shown to inhibit viral replication in vitro by interfering with the formation of the viral diphosphate. 2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde is a ribonucleotide that is synthesized from commercially available starting materials. This compound has shown to be active against HIV type 1 virus in vitro and has been proposed as a potential antiviral agent for the treatment of AIDS. 2-Methylsulfanyl-4-phenylamino pyrimidine 5 carbaldehyde (2MSAP) was found to be active against HIV type 1 virus in vitro and has been proposed as a potential antiviral agent for the treatment ofFórmula:C12H11N3OSPureza:Min. 95%Peso molecular:245.3 g/mol5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine
CAS:5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine is a nucleoside analog that is an activator of DNA polymerase. It has been shown to have anticancer activity in vitro and in vivo. 5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine was found to inhibit the proliferation of leukemia cells, human colon cancer cells, and human prostate cancer cells. This compound also inhibits viral replication by affecting the synthesis of viral DNA and RNA. 5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine may be used as a research tool for studying the mechanism of action of antiviral drugs suchFórmula:C37H37F3N4O9Pureza:Min. 95%Peso molecular:738.74 g/mol2-Amino-8-(2-deoxy-β-D-ribofuranosyl)-imidazo[1,2-α]-1,3,5-triazin-4(8H)-one
CAS:2-Amino-8-(2-deoxy-β-D-ribofuranosyl)-imidazo[1,2-α]-1,3,5-triazin-4(8H)-one is a modified nucleoside analog with the following structure: the core heterocyclic structure is a fused imidazole-triazine ring, there is a 2-amino group at position 2 of the imidazole ring and it has a 2-deoxy-β-D-ribofuranose sugar attached at the 8-position of the heterocyclic ring, making it structurally related to DNA nucleosides.Fórmula:C10H13N5O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:267.24 g/mol1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine
CAS:1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine is a synthetic, modified nucleoside that can be phosphorylated to its monophosphate form. It is an inhibitor of DNA synthesis and the replication of viral DNA. 1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine has been shown to have anticancer activity in vitro and in vivo. This drug is also active against some RNA viruses such as hepatitis B virus and human immunodeficiency virus type 1 (HIV).Fórmula:C9H12ClN3O4Pureza:Min. 95%Peso molecular:261.66 g/mol7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt is a nucleoside analog that inhibits telomerase. It binds to the catalytic subunit of telomerase, which is an RNA-dependent DNA polymerase that synthesizes telomeres during DNA replication. This binding prevents the enzyme from extending the 3' end of the DNA strand, inhibiting cell proliferation and leading to apoptosis. Telomerase inhibition has been shown to have an inhibitory effect on insulin resistance in mice. 7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt also inhibits protein kinases, but does not inhibit phosphatases or other enzymes.Fórmula:C11H17N4O13P3·xLiPureza:Min. 95%Peso molecular:506.19 g/mol5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine
5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine is a nucleoside analog that has antiviral, anticancer, and high purity properties. It is an activated nucleotide that can be incorporated into DNA or RNA. 5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine is a modified nucleoside with the deoxyribose sugar replaced by an isopropylidene group. This modification prevents the drug from being metabolized and excreted from the body. The drug is used to treat various cancers such as leukemia and lymphoma, as well as herpes simplex virus infections. It also has been shown to have antimicrobial properties against bacteria, fungi, and viruses.Fórmula:C12H15ClIN3O4Pureza:Min. 95%Peso molecular:427.63 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite is an antiviral agent that inhibits the synthesis of DNA. It can be used to treat AIDS, because it inhibits the reverse transcriptase enzyme. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite also has anticancer properties, which is due to its ability to inhibit RNA and protein synthesis in cancer cells. This compound has been synthesized by reacting 5'-O-DMT cytidine with methylacetoacetate under standard conditions. The modified nucleoside has a high purity, high quality, and novel structure.Fórmula:C47H64N7O7SiPureza:Min. 95%Peso molecular:867.14 g/mol2'-Deoxyadenosine-5'-carboxylic acid
CAS:dA oxidised at the 5'-position.Fórmula:C10H11N5O4Pureza:Min. 95%Peso molecular:265.23 g/mol4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-7-pteridone
4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-7-pteridone is a novel nucleoside that has been modified by the addition of a 2'-deoxy, 3',5'-di-O-toluoyl group on the sugar moiety. This modification increases the stability of 4AMDT in serum and enhances its antiviral activity against DNA and RNA viruses. It also inhibits the proliferation of cancer cells and induces cell death by inhibiting protein synthesis.Fórmula:C29H29N5O6Pureza:Min. 95%Peso molecular:543.57 g/mol2'-Deoxy-5-hydroxyuridine 5'-triphosphate
CAS:2'-Deoxy-5-hydroxyuridine 5'-triphosphate (doxorubicin) is a cytotoxic and chemotherapeutic agent that interferes with DNA replication. It is an oxidized form of the natural pyrimidine base thymine. The drug blocks DNA synthesis by preventing the incorporation of uracil into the newly synthesized strand, which causes strand breaks. Doxorubicin has been shown to be effective in treating a variety of cancers, including those of the breast, ovaries, bladder, and stomach. This drug can also cause severe side effects such as heart damage and hearing loss due to its interaction with cellular oxygen metabolism.Pureza:Min. 95%6-Chloro-9-(3',5'-di-O-benzoyl-2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)purine
CAS:6-Chloro-9-(3',5'-di-O-benzoyl-2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a nucleoside that is used as an anticancer and antiviral agent. It is synthesized from 9-(3',5'-di-O-benzoyl)-2'-deoxyribofuranosyl chloride, which is then chlorinated to form 6-chloro purine. This product has been shown to be active against human DNA tumor cells and other viruses in vitro. 6CPA, like other nucleosides, can be phosphorylated on the 3' or 5' position of the sugar moiety, yielding monophosphate or diphosphate derivatives respectively. The monophosphate derivative of 6CPA has a higher cytotoxicity than the diphosphate derivative. The deoxyribose sugar moiety canFórmula:C24H18CIFN4O5Pureza:Min. 95%Peso molecular:496.89 g/molN2-Isobutyryl-N-trityl-morpholinoguanine methyl dimethylphosphoramide chloridate
CAS:N2-Isobutyryl-N-trityl-morpholinoguanine methyl dimethylphosphoramide chloridate is a novel modified nucleoside analog with antiviral and anticancer activity. It is a phosphoramidite that is used in the synthesis of oligonucleotides and polynucleotides. N2-Isobutyryl-N-trityl-morpholinoguanine methyl dimethylphosphoramide chloridate has been shown to inhibit viral replication in vitro by inhibiting viral DNA polymerase, as well as tumor growth in vivo by inducing apoptosis. This compound has also been shown to be an activator for RNA polymerases I, II, and III.Pureza:Min. 95%N1-Methyladenosine hydroiodide
CAS:N1-Methyladenosine hydroiodide is a novel nucleoside analogue that inhibits viral replication by preventing the formation of viral DNA. It also inhibits the growth of cancer cells and is used as an anticancer drug. N1-Methyladenosine hydroiodide has been shown to be an activator of RNA polymerase II, increasing the production of messenger RNA (mRNA) in human cells. The phosphoramidite form of this compound is used for the synthesis of oligodeoxyribonucleotides, which are chemically modified in order to improve their stability and inhibit degradation by nucleases. N1-Methyladenosine hydroiodide is highly pure and has CAS No. 34308-25-3.Fórmula:C11H15N5O4·HIPureza:Min. 95%Peso molecular:409.18 g/mol3'-Azido-3'-deoxy-5-methylcytidine
CAS:3'-Azido-3'-deoxy-5-methylcytidine (AZDMC) is a novel nucleoside analog that inhibits viral replication. AZDMC is an activator of cellular DNA synthesis, which is essential for the replication of DNA and the production of RNA. It also has antiviral activity against influenza A and B viruses. The chemical name for AZDMC is 3'-azido-3'-deoxy-5-methylcytidine monophosphate (AMP). The CAS number for AZDMC is 1282040-14-5. It can be synthesized with high purity and quality by Ribonucleosides, Modified, Deoxyribonucleosides, Nucleosides, Phosphoramidites.
Pureza:Min. 95%N6-Benzoyl-3'-deoxyadenosine
CAS:N6-Benzoyl-3'-deoxyadenosine is a nucleoside analogue that is used as a substrate for DNA polymerase. The efficiency of this compound has been shown to be higher than other nucleotides. In addition, N6-Benzoyl-3'-deoxyadenosine has been shown to be an efficient donor in the ligation reaction and can also act as a competitive inhibitor of topoisomerase II. N6-Benzoyl-3'-deoxyadenosine is a scissile substrate for DNA topoisomerase II and cleaves at the same site as dATP. This compound has been shown to be active against both Gram-positive bacteria and Mycobacterium tuberculosis with high selectivity.Fórmula:C17H17N5O4Pureza:Min. 95%Peso molecular:355.35 g/mol8,5’(S)-Cycloguanosine
CAS:Please enquire for more information about 8,5’(S)-Cycloguanosine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C10H10N5O5Pureza:Min. 95%1,N6-Ethenoadenosine-5'-diphosphate, Sodium salt
CAS:Emission max - 415nmMolar extinction coefficient ε [L·mol⁻¹·cm⁻¹] - 6000Fluorescent analogue of 5'-ADP, NA10698Fórmula:C12H15N5O10P2Pureza:Min. 95%Peso molecular:451.22 g/molO6-Benzyl guanosine
CAS:O6-Benzyl guanosine is a polymerized compound that has been shown to have anticancer efficacy. It has been tested in mice with medulloblastoma, a type of brain tumor, and in rats with breast cancer. O6-Benzyl guanosine was found to be hydrophobic and bound to the methyltransferase enzyme, which resulted in the inhibition of DNA synthesis. The polymerized compound is able to form conjugates with other molecules such as iron oxide nanoparticles or hydrazone derivatives, which can be used for treatments that involve bioconjugate chemistry.Fórmula:C17H19N5O5Pureza:Min. 95%Peso molecular:373.36 g/mol5-Aminoallyluridine 5'-triphosphate sodium salt - 100mM aqueous solution
CAS:5-Aminoallyluridine 5'-triphosphate sodium salt is a modified nucleoside that has antiviral and anticancer activity. It is a prodrug of 5-aminoallyluridine and is activated by deoxyribonucleotide ribonucleotides in the cell. This drug also can be used as an activator for other drugs, such as cytosine arabinoside, which are inactive or less active when administered alone.Fórmula:C12H20N3O15P3·xNaPureza:Min. 95%Peso molecular:539.22 g/mol2'-Deoxy-8-(9H-fluoren-2-ylamino)-guanosine
CAS:2'-Deoxy-8-(9H-fluoren-2-ylamino)-guanosine (FdA) is a synthetic nucleoside that was designed for use as a dietary supplement to inhibit carcinogenesis. It is an analog of guanosine and is phosphorylated by cellular kinases to form 2'-deoxy-8-(9H-fluoren-2-ylamino)-inosine monophosphate. FdA inhibits the process of DNA replication in mammalian cells, which may be due to its ability to bind single stranded DNA. This drug has been shown to reduce the mutation frequency and increase the life span of mice with bladder cancer.Fórmula:C23H22N6O4Pureza:Min. 95%Peso molecular:446.46 g/mol6-(4-Iodobenzyl)-1-Methyl Pyrimidine-2,4-(1H,3H)-Dione
CAS:6-(4-Iodobenzyl)-1-Methyl Pyrimidine-2,4-(1H,3H)-Dione is a nucleoside analog that has shown to be an activator of the ribonucleotide reductase enzyme. It has also been shown to have anticancer activity. 6-(4-Iodobenzyl)-1-Methyl Pyrimidine-2,4-(1H,3H)-Dione inhibits DNA synthesis by binding to the DNA molecule at the site of incorporation and preventing its duplication. This compound also inhibits RNA synthesis by binding to the RNA molecule at the site of incorporation and preventing its duplication. It has been shown to inhibit cancer cell growth in culture and can be used as a chemotherapeutic agent.Fórmula:C12H11IN2O2Pureza:Min. 95%Peso molecular:342.13 g/molDihydrozeatin riboside-5'-monophosphate sodium salt
CAS:Dihydrozeatin riboside-5'-monophosphate sodium salt is a cytokinin that belongs to the group of indole compounds. It has been shown to inhibit the biosynthesis of ethylene, which prevents fruit from ripening. Dihydrozeatin riboside-5'-monophosphate sodium salt is also able to inhibit the synthesis of adenosine, another plant hormone that inhibits growth and promotes dormancy in plants. The bioassay for this product has been done with amanita muscaria, an edible mushroom found in North America and Europe. This mushroom contains dihydrozeatin as well as other related compounds such as zeatin, which can be converted into dihydrozeatin by enzymes present in the intestines. The symptoms of poisoning by this mushroom include vomiting and diarrhea, owing to its effects on intestinal motility.Fórmula:C15H22N5Na2O8P·H2OPureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:495.33 g/mol5-Chloro-2',3'-O-isopropylidenecytidine
5-Chloro-2',3'-O-isopropylidenecytidine is a synthetic nucleoside that is activated by phosphorylation to form the corresponding nucleotide. It has antiviral and anticancer properties, and can be used as a building block for synthesis of other nucleosides. 5-Chloro-2',3'-O-isopropylidenecytidine is synthesized from 2,4-dichlorophenoxyacetic acid (DCA) and 2,5-dichloroaniline in the presence of sodium cyanide. The compound was first synthesized in 1972 and its chemical structure was determined in 1974. 5-Chloro-2',3'-O-isopropylidenecytidine has been shown to inhibit DNA synthesis by binding to viral diphosphate and deoxyribonucleosides. This compound also inhibits the activity of bacterial DNA gyrase and DNA top
Fórmula:C12H16ClN3O5Pureza:Min. 95%Peso molecular:317.73 g/mol8-Oxo-7-thioguanosine
CAS:8-Oxoguanosine monophosphate (8-oxoGMP) is a synthetic nucleoside that is activated by the enzyme thioredoxin reductase and phosphorylated to form 8-oxoGTP. The anticancer activity of 8-oxoGMP is due to its ability to inhibit ribonucleotide reductase, which reduces the production of DNA and RNA in cells. This product has been shown to inhibit HIV replication in vitro and in vivo. It also inhibits viral replication by inhibiting the synthesis of viral nucleic acids such as DNA, RNA, and deoxyribonucleic acid (DNA).Fórmula:C10H12N4O6SPureza:Min. 95%Cor e Forma:PowderPeso molecular:316.29 g/mol2-Amino-benzoyl-9-(5'-O-DMT-b-D-ribofuranosyl)purine
2-Amino-benzoyl-9-(5'-O-DMT-b-D-ribofuranosyl)purine is an anticancer and antiviral agent. It has been shown to be active against many viruses, including herpes simplex virus type 1, herpes simplex virus type 2, cytomegalovirus, and human immunodeficiency virus type 1. This compound also exhibits antitumor activity in mice and rats.Fórmula:C38H35N5O7Pureza:Min. 95%Peso molecular:673.71 g/mol3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine
CAS:3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine is a nucleoside derivative that has antiviral activity. It is synthesized by the condensation of 2,3,5-trihydroxybenzoic acid with 3'-chloro-5'-fluoroacetophenone in the presence of pyridine and triethylamine. The nucleoside has been shown to be an effective inhibitor of HIV replication in vitro. 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine also inhibits DNA synthesis in human lymphocytes at concentrations of 5 μM or less. This compound can be used as an activator for DNA polymerases and phosphoramidites for DNA synthesis.Fórmula:C23H17Cl2FN2O7Pureza:Min. 95%Peso molecular:523.29 g/mol2'-Deoxy-3'-O-DMT-N2-iBu-guanosine--succinyl-CPG 1000 Å
2'-Deoxy-3'-O-DMT-N2-iBu-guanosine--succinyl-CPG 1000 Å is a modified nucleoside that is synthesized from 2'-deoxyribonucleosides and succinic anhydride. It has antiviral, anticancer, and antimalarial activities. It can also be used to modify DNA sequences. This product is a novel phosphoramidite monomer with high purity.
Pureza:Min. 95%8-Bromo-5'-o-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine
CAS:8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine (8-Bromo-5'-O-(DMT)-dG) is a novel nucleoside that is synthesized by reacting 8-bromo-5'-O-(dimethyoxytrityl)-2'-deoxyguanosine with dimethylaminomethylidene. It has antiviral, anticancer, and ribonucleoside activities. 8-Bromo-5'-O-(DMT)-dG is used as a building block for the synthesis of oligonucleotides, phosphoramidites, and other modified nucleosides. 8-Bromo-5'-O-(DMT)-dG is currently being developed as an anticancer drug.Fórmula:C34H35BrN6O6Pureza:Min. 95%Peso molecular:703.6 g/mol3',5'-Di-O-acetyl-N2-acetyl-O6-diphenylcarbamoyl-2'-deoxy-D-guanosine
3',5'-Di-O-acetyl-N2-acetyl-O6-diphenylcarbamoyl-2'-deoxy-D-guanosine is a synthetic nucleoside that has been modified with an acetyl group at the 3' and 5' positions of the sugar. It has antiviral, anticancer, and antiretroviral activities against HIV. This nucleoside has also been shown to inhibit human leukemia cells in vitro by binding to DNA, inhibiting its synthesis. The drug is currently undergoing clinical trials for the treatment of AIDS patients.Pureza:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine
CAS:2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is a modified nucleoside that is used to synthesize oligonucleotides. It is a phosphoramidite, and can be used in the synthesis of DNA or RNA. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is an antiviral agent that has been shown to have anticancer activity in animal models. It has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) and serum enzymes, such as dismutase activity, in mice with lung cancer. This drug also has a toxic effect on respiratory system cells, which may be due to its ability to induce apoptosis.
Pureza:Min. 95%Octanoyl coenzyme A potassium salt
CAS:Octanoyl CoA is a molecule that belongs to the class of acyl-coenzyme A. It is an important intermediate in fatty acid metabolism and is also used in the synthesis of long-chain fatty acids. Octanoyl CoA can be converted back to acetyl-CoA by enzymes called synthetases, which are active in energy metabolism. Octanoyl CoA has been shown to have clinical relevance for diseases such as acyl chain disorders, carnitine deficiency, and dehydrogenase deficiency. Octanoyl CoA is a potential drug target since it can be converted into octanoic acid, which has been shown to inhibit enzyme activities and protein synthesis.
Fórmula:C29H47N7O17P3S·3KPureza:Min. 95%Cor e Forma:PowderPeso molecular:1,008 g/mol3'-Amino-2',3'-dideoxy-2-fluoroadenosine
3'-Amino-2',3'-dideoxy-2-fluoroadenosine is a novel compound that inhibits the enzyme ribonucleotide reductase, which is involved in the synthesis of DNA. It also has antiviral and anticancer activities. 3'-Amino-2',3'-dideoxy-2-fluoroadenosine has high purity and high quality and can be used as an activator for phosphoramidite synthesis.Fórmula:C10H13FN6O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:268.25 g/mol3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite
CAS:3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite is a nucleotide analogue that is used in the synthesis of DNA. It is a modified nucleoside that contains an amino group at the 5' position of the pentose sugar and a methyl group at the 2' position. 3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite inhibits viral replication and has shown anticancer activity. It also possesses antiviral activity against Herpes simplex virus types 1 and 2, cytomegalovirus, varicella zoster virus, Epstein Barr virus, influenza A virus type A/PR/8/34 (H1N1), and human immunodeficiency virus type 1 (HIV).Fórmula:C40H49N4O8PPureza:Min. 95%Peso molecular:744.81 g/mol8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate Sp-isomer sodium
CAS:8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate Sp-isomer sodium salt (8-chloro-GTP) is a modified nucleoside that inhibits the synthesis of DNA by preventing the addition of nucleotides to the 3' end of DNA. It is an antiviral and anticancer agent, and can be used as a phosphoramidite in the synthesis of DNA. 8-chloro-GTP has shown high purity and high quality in synthesized DNA. Research on this compound is still ongoing, but it has been shown to be novel and modified compared to other nucleosides.
Fórmula:C16H14ClN5O6PS2·NaPureza:Min. 95%Peso molecular:525.86 g/mol5-Methyl-4’-thiocytidine
CAS:5-Methyl-4’-thiocytidine is an antiviral agent that has been shown to be effective against herpes simplex virus (HSV) type 1 and 2. 5-Methyl-4’-thiocytidine inhibits viral replication by competing with deoxyribonucleosides for incorporation into the viral DNA, which leads to the synthesis of defective DNA. This drug also has anticancer properties and is used in the treatment of leukemia, lymphoma, and carcinomas. 5-Methyl-4’-thiocytidine is a novel monophosphate nucleoside that can be used as an activator for phosphoramidite synthesis. The CAS number for this compound is 1312295-87-6. Synthesis of 5-methyl 4’ thiocytidine requires high purity, high quality nucleosides, and a novel phosphoramidite synthesis procedure.Pureza:Min. 95%6-Methylcytidine
CAS:6-Methylcytidine is a nucleoside that is structurally related to uridine, which is an acceptor in DNA and RNA synthesis. It is synthesized from 8-bromoadenosine, which undergoes deamination by cytidine deaminase. 6-Methylcytidine can be used as a building block for the synthesis of other nucleosides with different conformational properties. It has been shown to inhibit the replication of pancreatic cancer cells and has been used in molecular modeling studies. However, its uptake into cells has been found to be very low. This may be due to its conformational properties and the presence of 8-oxoguanosine, which inhibits adenosine uptake into cells.Fórmula:C10H15N3O5Pureza:Min. 95%Peso molecular:257.24 g/mol5-Iodo-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazo-4-carbonitrile
CAS:5-Iodo-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazo-4-carbonitrile is a nucleoside phosphoramidite that is synthesized from 2'-deoxyribose, 5'-iodoimidazole and triacetic acid. This compound is a novel phosphoramidite and can be used to synthesize DNA or RNA molecules. It has been shown to have anticancer properties, which may be due to its ability to inhibit DNA replication. 5-Iodo-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazo-4-carbonitrile also has antiviral properties and can be used as an activator in the synthesis of modified nucleosides.Fórmula:C15H16IN3O7Pureza:Min. 95%Peso molecular:477.21 g/mol5'-O-DMT-thymidine 3'-O-[(S-acetyl-6-thiohexyl) N,N-diisopropylphosphoramidite
5'-O-DMT-thymidine 3'-O-[(S-acetyl-6-thiohexyl) N,N-diisopropylphosphoramidite] is a novel compound that has been modified to enhance antiviral activity and provide protection against influenza virus. The phosphoramidite monophosphate is prepared by coupling of the 5'-O-DMT-thymidine 3'-O-[(S-acetyl-6-thiohexyl) N,N-diisopropylphosphoramidite] with an appropriate nucleoside phosphorylating agent, such as a thiophosphorylating agent. This product has high purity and quality.Pureza:Min. 95%5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite
CAS:5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite is a high purity, novel DNA monophosphate that is synthesized from 2',4'-diaminotoluene and 5'-O-dimethoxytritylthymidine. It has antiviral and anticancer properties and has shown to be an activator of RNA polymerase II in vitro. This product is used in many applications such as the synthesis of oligonucleotide probes for DNA sequencing, the synthesis of RNA for gene expression studies, and for the production of oligonucleotides for therapeutic purposes.Fórmula:C41H49N4O9PPureza:Min. 95%Peso molecular:772.82 g/mol5'-O-Acetyl-3'-azido-2',3'-dideoxy-N2-palmitoylguanosine
CAS:5'-O-Acetyl-3'-azido-2',3'-dideoxy-N2-palmitoylguanosine is a novel antiviral and anticancer agent. It is an analogue of the natural nucleoside guanosine. It has been modified with an acetyl group at the 5' position of the pentose moiety and an azido group at the 2' and 3' positions of the ribose moiety. The acetyl group makes this compound more water soluble, which means it can be easily administered intravenously for treatment of cancer or infection.Fórmula:C28H44N8O5Pureza:Min. 95%Peso molecular:572.7 g/molClofarabine 5'-monophosphate triethylammonium salt
CAS:Clofarabine is an anti-cancer drug that belongs to the class of diphosphate, Synthetic, Activator, Phosphoramidites, Deoxyribonucleosides. It is a modified nucleoside with antiviral and anticancer activity. Clofarabine 5'-monophosphate triethylammonium salt (CPF) has been shown to inhibit DNA synthesis by blocking the incorporation of deoxyribonucleotides into DNA. CPF binds to DNA at the 3' position of the deoxyribonucleotide chain, which prevents its extension and leads to inhibition of DNA replication. CPF also inhibits viral DNA synthesis through inhibition of viral DNA polymerase or viral RNA polymerase in vitro. Clofarabine is not active against bacteriophage T4 or bacterial RNA polymerase.Pureza:Min. 95%N-(2'-Deoxy- 2', 2'- difluorocytidine 5'-P- phenyl phosphate) L- alanine benzyl ester
CAS:N-(2'-Deoxy- 2', 2'- difluorocytidine 5'-P- phenyl phosphate) L- alanine benzyl ester, also known as Acelarin, is primarily used in cancer treatment, including leukemia and solid tumors.
Fórmula:C25H27F2N4O8PPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:580.47 g/mol2-Benzylthio-6-chloropurine
CAS:2-Benzylthio-6-chloropurine is a synthetic nucleoside analogue that is an antiviral agent. It inhibits the synthesis of viral DNA by competitive inhibition of thymidine kinase, which is an enzyme necessary for the conversion of deoxyribonucleotides to their monophosphate form. 2-Benzylthio-6-chloropurine has been found to be effective against herpes simplex virus 1 and 2 (HSV1 and HSV2). The drug is also active against HIV, influenza A virus, and cytomegalovirus.Fórmula:C15H9CIN4SPureza:Min. 95%Peso molecular:416.24 g/molThymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt
CAS:Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt is a nucleoside that is a synthetic analog of thymidine. It has antiviral activity and is used in the synthesis of DNA and RNA. This product has shown to be effective against HIV, influenza, polio, herpes, and human papillomavirus. Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt can also be used for the synthesis of phosphoramidites for oligonucleotide synthesis.Fórmula:C20H26N7O10P·NH3Pureza:Min. 95%Peso molecular:572.47 g/mol
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