Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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Biotin-5-deoxyuridine-5'-triphosphate, lithium salt - 1 mM aqueous solution
Biotin-5-deoxyuridine-5'-triphosphate, lithium salt is a novel phosphoramidite. It has been shown to be an anticancer agent and antiviral agent. Biotin-5-deoxyuridine-5'-triphosphate, lithium salt inhibits the growth of cancer cells by binding to the ribonucleotide reductase enzyme, thereby preventing synthesis of DNA and RNA.Fórmula:C22H34N5O16P3S·xLiPureza:Min. 95%Peso molecular:749.52 g/mol5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 5'-triphosphate
CAS:5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 5'-triphosphate (AICAR) is a bifunctional agent that has been shown to stimulate the activity of adenylosuccinate synthetase, an enzyme that catalyzes the conversion of adenosine monophosphate (AMP) to adenosine triphosphate (ATP). AICAR is also a substrate for adenylosuccinate synthetase. The use of AICAR as a pharmacological agent has been associated with increased levels of nucleotides in cells and tissues. This may be due to the activation of AMPK, which stimulates ATP production by breaking down ATP through oxidative phosphorylation. AICAR can be detected using chromatographic techniques, such as high performance liquid chromatography or thin layer chromatography.Fórmula:C9H17N4O14P3Pureza:Min. 95%Peso molecular:498.17 g/molN-Acetyl-5-[1,2-bis(acetyloxy)ethyl]-5'-O-DMT-2'-deoxycytidine
CAS:N-Acetyl-5-[1,2-bis(acetyloxy)ethyl]-5'-O-DMT-2'-deoxycytidine is a nucleoside that is modified with acetyl groups at the 2' and 5' positions of the deoxyribose sugar. It is used as an antiviral and anticancer agent. The acetyl groups on the 2' position prevent N-Acetyl-5-[1,2-bis(acetyloxy)ethyl]-5'-O-DMT-2'-deoxycytidine from being phosphorylated by cellular enzymes, which may be useful in cancer therapy. This compound also has high purity and can be used to synthesize other nucleosides.Fórmula:C47H58N5O12PPureza:Min. 95%Peso molecular:915.96 g/mol5-Bromo-2,4-di(benzyloxy)pyrimidine
CAS:5-Bromo-2,4-di(benzyloxy)pyrimidine is an activator of DNA and RNA synthesis. It is a phosphoramidite that is used in the synthesis of oligonucleotides. 5-Bromo-2,4-di(benzyloxy)pyrimidine has antiviral activity and can inhibit the replication of HIV in vitro. This compound also has anticancer activity when it is given as a monophosphate, while its diphosphate form inhibits DNA and RNA synthesis. 5-Bromo-2,4-di(benzyloxy)pyrimidine can be synthesized from 2,4-dibenzyloxy pyrimidine and bromine in high purity with a CAS number 41244-53-5.
Fórmula:C18H15BrN2O2Pureza:Min. 95%Peso molecular:371.23 g/molN4-Benzoyl-5-bromo-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite
CAS:N4-Benzoyl-5-bromo-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite is a novel modified cytosine derivative. It has anticancer activity and can be used in the treatment of cancer cells that are resistant to other anticancer drugs. This product has a high purity and quality, which allows it to be widely used in the synthesis of DNA, RNA, and ribonucleosides. In addition, N4-Benzoyl-5-bromo-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite is an activator for diphosphate formation as well as a nucleotide analogue with antiviral effects. This product is also an inhibitor of DNA polymerase α and β, which are enzymes involved in DNA replication.Fórmula:C46H51BrN5O8PPureza:Min. 95%Peso molecular:912.8 g/mol2-Methylthio-6-chloro-9-methylpurine
CAS:2-Methylthio-6-chloro-9-methylpurine is an activator that inhibits the enzyme ribonucleotide reductase, which is involved in the synthesis of DNA and RNA. 2-Methylthio-6-chloro-9-methylpurine has been shown to inhibit viral replication and may be used as a antiviral agent. This compound has novel properties and is a potential anticancer drug due to its ability to inhibit the growth of tumor cells.Fórmula:C7H7CIN4SPureza:Min. 95%Peso molecular:318.14 g/mol2',3',5'-Triacetyl -azacytidine
CAS:2',3',5'-Triacetyl-azacytidine is a transcription factor that has dose-dependent effects on the production of melanin. It inhibits the synthesis of melanin by binding to two specific transcription factors, the microphthalmia-associated transcription factor and the histone methyltransferases. This drug also inhibits tyrosinase, which is an enzyme involved in the production of melanin. 2',3',5'-Triacetyl-azacytidine has been shown to inhibit the growth of murine melanoma cells and may be useful for treating skin cancer.Fórmula:C14H18N4O8Pureza:Min. 95%Peso molecular:370.31 g/mol2'-O-Me-5'-O-DMT-1,3-di-N-POM-pseudouridine-3'-CE phosphoramidite
2'-O-Me-5'-O-DMT-1,3-di-N-POM-pseudouridine-3'-CE phosphoramidite is an antiviral agent that inhibits the synthesis of RNA. It has been shown to inhibit the production of new viruses in cultured cells and to be active against some strains of influenza virus. The modification was developed by chemists at Boehringer Ingelheim, who have also synthesised other novel nucleosides that are being tested as anticancer agents. This product is a monophosphate derivative with a high purity level and a CAS number.Pureza:Min. 95%3'-Deoxy-3'-fluoro-5'-O-tritylthymidine
CAS:3'-Deoxy-3'-fluoro-5'-O-tritylthymidine is a monophosphate nucleoside that inhibits the viral DNA polymerase. It has antiviral activity against herpes viruses, including HSV-1 and HSV-2. 3'-Deoxy-3'-fluoro-5'-O-tritylthymidine is a synthetic nucleoside with modified phosphate groups to improve stability and purity. This product has shown anticancer effects in vitro and in vivo by inhibiting DNA synthesis and promoting apoptosis of cancer cells.Fórmula:C29H27FN2O4Pureza:Min. 95%Peso molecular:486.53 g/mol2'-Deoxy-5-fluorouridine 5'-diphosphate sodium salt
CAS:2'-Deoxy-5-fluorouridine 5'-diphosphate sodium salt is an antiviral agent that inhibits the synthesis of viral RNA. It is a modified monophosphate nucleotide that is used to treat hepatitis B and C virus infections, as well as AIDS. This drug has been shown to be effective in treating cancer cells, such as leukemia and lymphoma. 2'-Deoxy-5-fluorouridine 5'-diphosphate sodium salt has also been shown to have anticancer properties against colon cancer cells.Fórmula:C9H13FN2O11P2·xNaPureza:Min. 95%2-Amino-6-chloro-4-methoxypyrimidine
CAS:2-Amino-6-chloro-4-methoxypyrimidine (2ACMP) is a molecule that has been synthesized by the process of asymmetric synthesis. It is soluble in ethyl formate and has shown to be a strong inhibitor of the enzyme uv absorption, with an inhibition constant of 1.0 x 10 M. 2ACMP has been shown to inhibit molecular processes such as vibrational excitation, molecular modeling, and surface methodology. This molecule also binds to metal hydroxides and can be used for process optimization when combined with solubility data and nutrient solutions.
Fórmula:C5H6ClN3OPureza:Min. 95%Peso molecular:159.57 g/molRSPACER CEP
CAS:RSPACER CEP is a novel synthetic oligonucleotide with anti-cancer and antiviral activity. The product has been shown to inhibit the proliferation of tumor cells in vitro and reduce the production of pro-inflammatory cytokines in macrophages. The product is phosphoramidite, which is an intermediate for the chemical synthesis of DNA. It is synthesized from deoxyribonucleosides, modified nucleosides, and monophosphate nucleotides. RSPACER CEP also has antiviral properties that are mediated by inhibiting viral RNA replication in infected cells through inhibition of viral polymerase.Fórmula:C41H59N2O7PSiPureza:Min. 95%Peso molecular:751 g/mol8-Chloroadenosine 3',5'-cyclic monophosphate
CAS:8-Chloroadenosine 3',5'-cyclic monophosphate (8-CAM) is a potent inducer of the mitochondrial membrane potential. It has been shown to have cytotoxic effects on human myeloma cell line, HL-60 cells, and fetal bovine serum. 8-CAM has shown anticancer properties in solid tumours in mice. It was also found to be toxic to human carcinoma cell lines and synergistic with other pharmacological agents, such as doxorubicin. 8-CAM has been shown to have immunosuppressive effects in animal models and may be a potential therapeutic agent for autoimmune diseases.Fórmula:C10H11ClN5O6PPureza:Min. 95%Cor e Forma:White PowderPeso molecular:363.65 g/mol6-Azathymidine
CAS:6-Azathymidine is an antiviral agent that prevents the synthesis of viral DNA. It is a nucleoside analogue that contains a hydroxyl group at the 6 position on a pyrimidine ring. This compound has been shown to be effective in treating HIV infection and cancer, as well as herpes simplex virus and influenza virus. 6-Azathymidine inhibits the enzyme ribonucleotide reductase, which is responsible for converting ribonucleotides into deoxyribonucleotides, thereby blocking DNA synthesis. The phosphate derivatives of this drug have been shown to inhibit the biosynthesis of human immunodeficiency virus (HIV) by interfering with intermolecular hydrogen bonding between guanine and adenine.
Fórmula:C9H13N3O5Pureza:Min. 95%Peso molecular:243.22 g/mol2'-C-Methyluridine 5'-triphosphate lithium salt - 10mM aqueous solution
2'-C-Methyluridine 5'-triphosphate lithium salt is a nucleoside that is a high quality, activator and novel. It is used to synthesize ribonucleosides and deoxyribonucleosides. This drug has anticancer properties and can be used as an immunomodulator. 2'-C-Methyluridine 5'-triphosphate is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.Fórmula:C10H13N2O15P3Li4Pureza:Min. 95%Peso molecular:521.9 g/mol5-Bromo-5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite
5-Bromo-5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite is a novel, modified nucleoside and diphosphate that has antiviral activity. It is synthesized from 5-bromouracil and 2'-O-methyluridine by the use of a high purity reagent. The product is an anticancer agent that can be used to treat different types of cancer. This compound has also shown to have high purity and high quality.Fórmula:C40H48BrN4O9PPureza:Min. 95%Peso molecular:839.71 g/mol3'-Deoxy-3'-fluorothymidine-5'-triphosphate sodium salt
3'-Deoxy-3'-fluorothymidine-5'-triphosphate sodium salt (3'-DFP) is a modified nucleoside that acts as an antiviral and anticancer drug. It is a monophosphate derivative of thymidine, which is converted to diphosphate by the enzyme thymidylate kinase. 3'-DFP inhibits DNA synthesis by preventing the incorporation of deoxyribonucleotides into DNA. 3'-DFP can also be used as a building block in the synthesis of other nucleosides such as cytidine 5′-triphosphate, uridine 5′-triphosphate, and adenosine 5′-triphosphate. 3'-DFP is active against herpesviruses including Epstein-Barr virus, cytomegalovirus, and varicella zoster virus. It has also been shown to inhibit cancer cell proliferation when used at high doses.Pureza:Min. 95%6-Chloro-9-methylpurine
CAS:6-Chloro-9-methylpurine is an inhibitor of the enzyme kinase. It has been shown to inhibit the activity of 6-chloropurine phosphohydrolase and 6-chloropurine nucleoside phosphorylase, which are important enzymes in purine metabolism. 6-Chloro-9-methylpurine can be used to treat a number of diseases, including myeloid leukemia, where it inhibits the production of nucleic acids. This drug has also been shown to inhibit the growth of lettuce by inhibiting chlorophyll synthesis.Fórmula:C6H5ClN4Pureza:Min. 95%Peso molecular:168.58 g/mol3'-O-Azidomethyl 2'-deoxyguanosine 5'-O-triphosphate sodium salt
3'-O-Azidomethyl 2'-deoxyguanosine 5'-O-triphosphate sodium salt is an antiviral and anticancer agent used in the treatment of HIV, hepatitis B, hepatitis C, herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, cytomegalovirus, Epstein-Barr virus, and Kaposi's sarcoma. It is a nucleotide analog that inhibits viral replication by inhibiting DNA synthesis. The phosphate group on this compound is modified with an azide group to inhibit deamination by phosphodiesterases. This product has been shown to be effective against leukemia cells.Pureza:Min. 95%2'-O-tert-Butyldimethylsilyl-3'-deoxy-5-methyluridine
CAS:2'-O-tert-Butyldimethylsilyl-3'-deoxy-5-methyluridine (2'-O-TBDMS-5'-dMU) is a synthetic nucleoside that is an antiviral agent. It has been shown to be an activator of DNA polymerase, which may be due to its ability to bind to the enzyme's catalytic site and inhibit the enzyme's activity. 2'-O-TBDMS-5'-dMU also has high purity and can be used in the synthesis of modified nucleosides, phosphoramidites, diphosphates, and ribonucleosides. 2'-O-TBDMS-5'-dMU is a white powder with a melting point of about 221°C. It is soluble in water and alcohols and insoluble in acetone or ether.Fórmula:C16H28N2O5SiPureza:Min. 95%Peso molecular:356.49 g/mol
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