Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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Pyrimidine-5-carboxamidine hydrochloride
CAS:Pyrimidine-5-carboxamidine hydrochloride (GC) is a guanosine analog that inhibits bacterial growth by binding to the anticodon region of ribosomes. GC has been shown to bind to the replicons of many organisms, including bacteria, and inhibit the formation of mRNA from DNA. This drug also inhibits methyltransferase, which prevents transfer RNA from being modified with methionine. GC may be used in research for eukaryotes and deamination reactions in trna modification.Fórmula:C5H6N4·HClPureza:Min. 95%Peso molecular:158.59 g/mol2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine
CAS:2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine (ABT-888) is a nucleoside analog that inhibits DNA synthesis and RNA transcription. It has been shown to induce apoptosis in human cancer cells, including leukemia, lymphoma and breast cancer cells. ABT-888 also has antiviral activity against herpes simplex virus type 1 and 2, vaccinia virus, and vesicular stomatitis virus.Fórmula:C19H20N2O7Pureza:Min. 95%Peso molecular:388.37 g/molBiotin-16-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution
CAS:Biotin-16-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution is a synthetic nucleotide that contains the natural nucleoside uridine and the modified nucleoside 5-biotin. It is an activator of DNA polymerase. Biotin-16-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution has antiviral properties as it inhibits HIV reverse transcriptase and human cytomegalovirus (HCMV) DNA polymerase. It also inhibits human telomerase activity by preventing telomeric DNA synthesis. The high purity of this product allows for its use in many different research applications.Fórmula:C32H52N7O19P3S·xLiPureza:Min. 95%Peso molecular:963.78 g/mol3'-Azido-3'-deoxy-5-fluorocytidine
CAS:3'-Azido-3'-deoxy-5-fluorocytidine is an activator with novel antiviral and anticancer properties. It is a high quality, modified nucleoside that can be used to synthesize deoxyribonucleosides and ribonucleosides. 3'-Azido-3'-deoxy-5-fluorocytidine has been shown to inhibit the growth of cancer cells in vitro and in vivo.
Pureza:Min. 95%TFA-aa-dC
CAS:TFA-aa-dC is a novel anti-cancer drug that has been shown to have both antiviral and anticancer activities. It is a modified phosphoramidite of 2'-deoxyadenosine 5'-triphosphate with a 3'-amino group (TFA-aa-dC) and an acetyl group at the 2' position. TFA-aa-dC blocks viral replication by inhibiting the activity of viral DNA polymerase, which is required for DNA synthesis. The compound also inhibits cell growth by blocking RNA synthesis and protein production, leading to cell death. TFA-aa-dC has shown efficacy in preclinical studies against cervical cancer and leukemia cells.
Fórmula:C14H17F3N4O5Pureza:Min. 95%Peso molecular:378.3 g/mol2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine
CAS:2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine is a novel nucleoside analogue that inhibits the proliferation of cancer cells. It is an activator of ribonucleotide reductase, which converts ribonucleosides to deoxyribonucleosides and thereby prevents viral replication. 2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine has antiviral activity against influenza A virus and herpes simplex virus type 1 (HSV-1) in cell culture. This drug also has an inhibitory effect on the DNA polymerases and other enzymes involved in DNA synthesis. 2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine is a high quality product with high purity, CAS No. 1000203-40-6.Pureza:Min. 95%N4-Acetyl-5'-O-DMT-cytidine 3'-succinyl CPG 1000 Å (RNA)
N4-Acetyl-5'-O-DMT-cytidine 3'-succinyl CPG 1000 Å (RNA) is a novel, high quality, high purity, synthetic nucleoside analogue. It has antiviral and anticancer properties.Pureza:Min. 95%5'-O-DMT-thymidine 3'-Rp-oxazaphospholidine
5'-O-DMT-thymidine 3'-Rp-oxazaphospholidine is a novel nucleoside analogue. It has antiviral activity and can be used to treat infections caused by herpes virus. It also has anticancer activity against some types of cancer cells and can inhibit the growth of tumour cells. 5'-O-DMT-thymidine 3'-Rp-oxazaphospholidine acts as an inhibitor of DNA polymerase, preventing the synthesis of DNA from RNA. It also inhibits ribonucleotide reductase, which is involved in the production of ribonucleotides from diphosphate nucleotides. This drug can be used as a monophosphate or phosphoramidite for the synthesis of oligodeoxyribonucleotides and deoxyribonucleotides.
Pureza:Min. 95%3'-O-Azidomethyl 2'-deoxycytidine 5'-O-triphosphate sodium salt
3'-O-Azidomethyl 2'-deoxycytidine 5'-O-triphosphate sodium salt is a modified nucleoside that inhibits the synthesis of DNA. It has been shown to be an effective antiviral agent and can be used to treat cancer. 3'-O-Azidomethyl 2'-deoxycytidine 5'-O-triphosphate sodium salt is synthesized by reacting cytidine monophosphate with sodium azide in the presence of a triphosphorylating reagent. 3'-O-Azidomethyl 2'-deoxycytidine 5'-O-triphosphate sodium salt also inhibits DNA polymerase, which prevents the synthesis of RNA and proteins. The phosphoramidites are commercially available, high quality, and have a purity greater than 99%. This product is not currently approved by the FDA for use in humans or animals.Fórmula:C10H17N6O13P3·xNaPureza:Min. 95%Peso molecular:522.2 g/mol2’,3’-Bis-O-tert-butyldimethylsilyl-2-thiouridine
CAS:2’,3’-Bis-O-tert-butyldimethylsilyl-2-thiouridine is a modified nucleoside composed of 2-thiouracil (2-thiopyrimidine), a modified uracil where the oxygen at the 2-position is replaced by sulfur. Possible applications as its use as an intermediate in the chemical synthesis of RNA oligonucleotides.Fórmula:C21H40N2O5SSi2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:488.79 g/mol6-Methylthioinosine-5’-triphosphate sodium salt - 10 mM aqueous solution
CAS:6-Methylthioinosine-5’-triphosphate sodium salt - 10 mM aqueous solution is a synthetic, modified ribonucleoside that is an activator of the antiviral response. It has been shown to inhibit the replication of both DNA and RNA viruses in vitro. 6-Methylthioinosine-5’-triphosphate sodium salt - 10 mM aqueous solution is also used as a precursor in the synthesis of phosphoramidites. The CAS number for this product is 51464-82-5.Fórmula:C11H17N4O13P3SPureza:Min. 95%Peso molecular:538.26 g/mol5'-O-DMT-guanosine-(dmf) 3'-succinyl CPG 500 Å (RNA)
5'-O-DMT-guanosine-(dmf) 3'-succinyl CPG 500 Å (RNA) is a synthetic, modified nucleoside with the chemical name 5-O-dimethoxytrityl-guanine. It is a high purity and quality nucleoside that is synthesized from the corresponding ribonucleoside or deoxyribonucleoside by phosphoramidite chemistry. This compound has been shown to have anticancer and antiviral activity. The chemical formula for this compound is C14H12N4O8PS2, molecular weight of 692.5 g/mol, and CAS number 25608-06-0.Pureza:Min. 95%5'-O-tert-Butyldimethylsilylthymidine
CAS:5'-O-tert-Butyldimethylsilylthymidine is a nucleoside that is used for the synthesis of oligoribonucleotides. It can be prepared by treating 5'-O-tert-butyldimethylsilylthymidine with alkyl bromides in the presence of microwaves and catalytic amounts of a base such as sodium methoxide. The product is purified by vacuum distillation or column chromatography and can be hydrolyzed to uridine, which has been shown to have anti-inflammatory properties. 5'-O-tert-Butyldimethylsilylthymidine can also be converted into deoxyribose through the use of ultrasound.Fórmula:C16H28N2O5SiPureza:Min. 95%Peso molecular:356.5 g/mol2’-Deoxy-3’-O-DMT-5'-O-phenoxyacetyladenosine
CAS:2' -Deoxy-3' -O-DMT-5'-O-phenoxyacetyladenosine is an activator of the DNA and RNA polymerases, which are enzymes that synthesize DNA and RNA. It can be used in the synthesis of modified DNA or RNA, as well as to investigate the anticancer activity of nucleosides. This compound has been shown to have antiviral effects in vitro by inhibiting viral protein synthesis. 2' -Deoxy-3' -O-DMT-5'-O-phenoxyacetyladenosine is a novel compound with high purity and high quality. CAS No.: 115388-94-8Fórmula:C39H37N5O7Pureza:Min. 95%Peso molecular:687.74 g/mol8-Chloroadenosine 3',5'-cyclic monophosphate
CAS:8-Chloroadenosine 3',5'-cyclic monophosphate (8-CAM) is a potent inducer of the mitochondrial membrane potential. It has been shown to have cytotoxic effects on human myeloma cell line, HL-60 cells, and fetal bovine serum. 8-CAM has shown anticancer properties in solid tumours in mice. It was also found to be toxic to human carcinoma cell lines and synergistic with other pharmacological agents, such as doxorubicin. 8-CAM has been shown to have immunosuppressive effects in animal models and may be a potential therapeutic agent for autoimmune diseases.Fórmula:C10H11ClN5O6PPureza:Min. 95%Cor e Forma:White PowderPeso molecular:363.65 g/mol1-(2-C-Methyl-b-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide
CAS:1-(2-C-Methyl-b-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide is a modified nucleoside that is used as an antiviral and anticancer agent. It is a diphosphate derivative of 1-(2'-deoxyribofuranosyl)-1H-1,2,4-triazole. The compound has been shown to have antiviral activity against herpes simplex virus (HSV) type I and HSV type II in vitro. It also inhibits the growth of human tumor cells in culture by interfering with DNA synthesis. The compound has been reported to be active against leukemia cells in vivo but not against normal cells. It has a high level of toxicity at high doses.
Pureza:Min. 95%Biotin-16-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution
Biotin-16-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution is a novel nucleoside that can be used for the treatment of cancer. It is phosphorylated to become biotin-16-cytidine-5'-triphosphate and then incorporated into DNA. This drug inhibits the production of tumor necrosis factor (TNF) and is active against HIV, herpes simplex virus type 2, and varicella zoster virus. Biotin-16-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution has also shown antiviral effects in vitro and in vivo.Fórmula:C32H52N8O18P3SPureza:Min. 95%Peso molecular:961.79 g/mol5'-O-DMT-5-methyl-2'-O-pentyluridine 3'-O succinate triethylammonium salt
5'-O-DMT-5-methyl-2'-O-pentyluridine 3'-O succinate triethylammonium salt is a monophosphate nucleoside. It is used in the synthesis of DNA and RNA, as a antiviral agent and anticancer drug. 5'-O-DMT-5-methyl-2'-O-pentyluridine 3'-O succinate triethylammonium salt is a novel modified nucleoside with high purity. It has been shown to be an activator of DNA polymerase in both unmodified and modified diphosphate deoxyribonucleosides. This product is CAS No. 91411-30-1.Fórmula:C40H45N2O11·C6H16NPureza:Min. 95%Peso molecular:832.01 g/mol2'-Deoxy-2'-fluorouridine-5'-monophosphate
CAS:2'-Deoxy-2'-fluorouridine-5'-monophosphate is a novel anticancer drug that inhibits the proliferation of cancer cells. It is a phosphoramidite monophosphate nucleoside analog and is used in the synthesis of DNA. This product can be used as an antiviral agent against herpes simplex virus and influenza A by inhibiting viral DNA polymerase, as well as being used to treat HIV infection by inhibiting reverse transcriptase. 2'-Deoxy-2'-fluorouridine-5'-monophosphate can also be used to inhibit tumor growth by inhibiting the synthesis of deoxyribonucleosides and nucleotides, thereby preventing DNA replication.Fórmula:C9H12FN2O8PPureza:Min. 95%Peso molecular:326.17 g/mol9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite
CAS:9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite is a novel nucleoside analogue that has shown to be effective against cancer. This product can also be used as an antiviral and antifungal agent. It is synthesized from 2,3,4,5,6-pentaacetoxybenzaldehyde and chloroacetamide. 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite is a high quality product that is made of Ribonuclesides, Synthetic Monophosphate Nucleosides Diphosphate Modified Deoxyribonucleosides Activator.Fórmula:C44H53FN7O8PPureza:Min. 95%Cor e Forma:White to off-white solid.Peso molecular:857.93 g/mol
