Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine
CAS:4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine is an anti-inflammatory drug that is used to treat bowel disease. It is also used as a polymer conjugate to treat cancer, and in the prevention of transplant rejection. 4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine has been shown to have antioxidant properties and may be effective in preventing inflammatory diseases such as inflammatory bowel disease. It has also been shown to act as an antihypertensive agent by inhibiting angiotensin I converting enzyme (ACE).Fórmula:C5H5N5OPureza:Min. 95%Peso molecular:151.13 g/mol1-(2'-Deoxy-2'-fluoro-a-L-arabinofuranosyl)-thymine
CAS:1-(2'-Deoxy-2'-fluoro-α-L-arabinofuranosyl)-thymine (commonly abbreviated as L-FMAU) is a nucleoside analog. It contains an α-L-arabinofuranose sugar instead of the natural β-D-deoxyribose found in DNA. A fluorine (F) substitution at the 2'-position enhances stability and resistance to enzymatic degradation. The thymine nucleobase allows it to mimic natural thymidine, potentially incorporating into DNA synthesis pathways. It can be research for its potential antiviral activity.Fórmula:C10H13FN2O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:260.22 g/mol3'-O, N4-Diacetyl-2'-deoxycytidine
<p>3'-O, N4-Diacetyl-2'-deoxycytidine is a modified nucleoside that has anticancer and antiviral activities. It inhibits the synthesis of DNA by preventing the formation of deoxyribonucleotide triphosphates. 3'-O, N4-Diacetyl-2'-deoxycytidine is a novel nucleoside with high purity and high quality. The CAS number for this product is 61428-37-5. This product can be used as starting material in the synthesis of phosphoramidites or modified oligonucleotides.</p>Fórmula:C13H17N3O6Pureza:Min. 95%Peso molecular:311.29 g/mol3'-b-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine
<p>3'-b-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine is a phosphoramidite, which is an intermediate in the synthesis of nucleosides. It is a novel deoxyribonucleoside that has been modified to include a methyl group at the 5' position. 3'-b-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine is often used as an activator for DNA polymerases and ribonucleases, as well as for the synthesis of ribonucleosides. This product has shown anticancer activity by inhibiting RNA synthesis.</p>Pureza:Min. 95%Peso molecular:227.22 g/mol1,3-Dimethylpseudouridine
CAS:<p>1,3-Dimethylpseudouridine is a methylated derivative of pseudouridine, which is a naturally occurring modified nucleoside found in RNA. This compounds can be used in research applications</p>Fórmula:C11H16N2O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:272.25 g/molAdenosine 2',3'-cyclic monophosphate sodium
CAS:Adenosine 2',3'-cyclic monophosphate sodium (AMP-Na) is a chemical compound that is found in Streptomyces coelicolor. It has been shown to have an active role in the biotechnology industry for research and development. AMP-Na inhibits the synthesis of carbohydrates by binding to enzymes such as adenosyl-l-methionine peroxidase, which is involved in the metabolism of carbohydrates. Adenosine 2',3'-cyclic monophosphate sodium also has a long half-life, which makes it useful for therapeutic purposes.Fórmula:C10H11N5NaO6PPureza:Min. 95%Cor e Forma:PowderPeso molecular:351.19 g/mol3’-b-C-Methyladenosine
CAS:3’-b-C-Methyladenosine is a novel antiviral and anticancer agent that is synthetically derived from deoxyribonucleosides. 3’-b-C-Methyladenosine has been shown to have antiviral activity against HIV, influenza, herpes simplex virus type 1 and type 2, and vaccinia virus. It also has anticancer activity against leukemia cells. 3’-b-C-Methyladenosine can be used as a phosphoramidite in the synthesis of oligonucleotides. It may be useful as an activator for nucleophilic substitution reactions with phosphorus halides.Pureza:Min. 95%5-b-D-Glucopyranosyl-5-thio-thymine
<p>5-b-D-Glucopyranosyl-5-thio-thymine is a novel, synthetic nucleoside that has antiviral activity. It is deoxyribonucleosides and ribonucleosides, which are the building blocks of DNA and RNA respectively. 5-b-D-Glucopyranosyl-5-thio-thymine can be used as an activator for phosphoramidites, which are used in the synthesis of DNA and RNA. This modified nucleotide also has anti cancer properties as it inhibits the growth of tumor cells.</p>Pureza:Min. 95%4’-C-Methyl-5-methylcytidine
CAS:<p>4’-C-Methyl-5-methylcytidine is a phosphoramidite nucleoside that is used as a reagent in the synthesis of DNA. It is modified with a 4′-methyl and 5′-methyl group at the C4 and C5 positions of the cytosine base, respectively. The 4′-C methyl group is an antiviral agent that inhibits viral replication by inhibiting reverse transcriptase. The 5′-methyl group prevents deamination of cytosine residues by inhibiting uracil glycosylase. This product has anticancer properties due to its ability to inhibit cell division and activate apoptosis in tumor cells.</p>Pureza:Min. 95%6-Dimethylamino-9-(b-D-ribofuranosyl)purine
CAS:<p>6-Dimethylamino-9-(b-D-ribofuranosyl)purine (6-DMAP) is an analog of adenine that has been shown to have anticancer activity in human serum and tissue culture. 6-DMAP can inhibit the synthesis of ATP, leading to cell death by significantly inhibiting cellular processes such as glycolysis and DNA replication. 6-DMAP also has a significant cytotoxicity on various types of cancer cells and plant tissues. The mechanism of action for the anticancer activity of 6-DMAP is not yet known, but it may be due to its ability to interfere with purine metabolism or its ability to form covalent bonds with DNA.</p>Fórmula:C12H17N5O4Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:295.3 g/molN6-Benzoyl-2'-O-(2-methoxyethyl)adenosine
CAS:<p>N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine is a novel nucleoside that can be used as an antiviral agent. It is an activator of viral polymerase and inhibits the proliferation of cells infected with HIV. This compound has been synthesized from 2'-deoxyadenosine monophosphate, which is a precursor to RNA and DNA synthesis. N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine has also been shown to inhibit the growth of experimental tumors in mice. The synthesis of this compound is reliable and reproducible, making it a high quality product.</p>Fórmula:C20H23N5O6Pureza:Min. 95%Peso molecular:429.43 g/mol5-(Azidomethyl)-2’-deoxyuridine
CAS:<p>5-azidomethyl-2-deoxyuridine (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similarly to EdU (NE08701). Unlike EdU that needs to be further modified with azides in the presence of copper catalyst, AmdU can also react in the absence of copper catalyst using spAAC Click Chemistry with strained cycloalkynes, such as cyclooctynes. This enables detection of nascent DNA in benign, copper free conditions.</p>Fórmula:C10H13N5O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:283.24 g/mol8-Bromoguanosine 3',5'-cyclic monophosphate sodium salt
CAS:Activator of cGMP-dependent protein kinasesFórmula:C10H10BrN5NaO7PPureza:Min. 95%Cor e Forma:PowderPeso molecular:446.08 g/mol2'-Deoxy-5'-DMT-5-(prop-2-yn-1-ylcarbamoyl)uridine 3'-CE phosphoramidite
2'-Deoxy-5'-DMT-5-(prop-2-yn-1-ylcarbamoyl)uridine 3'-CE phosphoramidite is a diphosphate nucleoside that is used in the synthesis of DNA. It has been modified with an acetyl group at the 2' position and a propargylamine group at the 5' position. This modification improves its stability to hydrolysis by esterases and also increases binding affinity for cationic lipids. The purified material is suitable for use in a variety of DNA syntheses, including PCR amplification, gene cloning, and site-directed mutagenesis.Pureza:Min. 95%3'-O-Methyl-5-methylcytidine
CAS:3'-O-Methyl-5-methylcytidine is a nucleoside with antiviral and anticancer properties. It has been shown to be an activator of RNA polymerase, the enzyme that catalyzes the transcription of DNA into RNA. 3'-O-Methyl-5-methylcytidine binds to the active site of RNA polymerase and is able to stimulate transcription in vitro. This drug has also been shown to have high purity and high quality.Fórmula:C11H17N3O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:271.27 g/mol2-Chloro-N6-cyclopentyladenosine hemihydrate
CAS:2-Chloro-N6-cyclopentyladenosine hemihydrate is a synthetic adenosine analog with potential research applicationsFórmula:C15H20ClN5O4H2OPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:378.81 g/molN4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite
N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is a novel nucleoside that has been modified by the addition of a benzoyl group to the 5' position of the ribonucleotide moiety. N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is an anticancer and antiviral agent that inhibits viral replication by competitive inhibition of DNA polymerase. N4-Benzoyl-5'-O-benzoyl -2'-O -tert -butyldimethylsilylcytidine 3'-CE phosphoramidite is active against HIV, herpes virus, and cytomegalovirus. This compound also inhibits the synthesisFórmula:C38H52N5O8PSiPureza:Min. 95%Peso molecular:765.93 g/molN2-DMF-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite
<p>N2-DMF-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite is a nucleoside analog that inhibits the growth of cancer cells. It is a modified nucleoside that has been used to synthesize phosphorothioate oligonucleotides and has been shown to have antiviral and anticancer activities. This compound binds with high affinity to the active site of DNA polymerase, preventing incorporation of ribonucleosides into DNA. N2-DMF-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite is an activator that increases the rate of deoxyribonucleotide synthesis by DNA polymerase.</p>Pureza:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-DMT-inosine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-5'-O-DMT-inosine 3'-CE phosphoramidite is a modified ribonucleoside with antiviral and anticancer properties. Its DNA synthesis inhibitory activity has been shown in vitro. It is capable of inhibiting the growth of cells infected with influenza A virus, herpes simplex virus type 2, and human lymphocytic leukemia cells. This compound can also be used to produce synthetic oligonucleotides for research purposes. SELECTIVE: The following description should only be used for products that are specifically designed for one gender or age group:Fórmula:C46H61N6O8PSiPureza:Min. 96 Area-%Cor e Forma:PowderPeso molecular:885.07 g/molBBQ-650-DT CEP
CAS:BBQ-650-DT CEP is an antiviral compound that is a phosphoramidite derivative of cytidine. BBQ-650-DT CEP has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in vitro, and to inhibit tumor cell proliferation in vivo. BBQ-650-DT CEP also inhibits the synthesis of RNA and DNA, which may have anticancer properties. This compound has been shown to be active against leukemia cells, lymphoma cells, and various breast cancer cell lines. It has also been shown to induce apoptosis in leukemia cells.Fórmula:C76H89N12O15PPureza:Min. 95%Peso molecular:1,441.6 g/mol
