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Nucleosídeos

Nucleosídeos

Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.

Foram encontrados 3569 produtos de "Nucleosídeos"

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  • L-Adenosine 5'-monophosphate disodium

    CAS:
    L-Adenosine 5'-monophosphate disodium is a high quality, novel, modified phosphoramidite used for the synthesis of deoxyribonucleosides and nucleosides. It is also used as an antiviral agent and has anti-cancer properties. L-Adenosine 5'-monophosphate disodium is an activator of ribonucleoside activities and inhibits viral replication by inhibiting the enzyme RNA polymerase. It has been shown to be effective against HIV, herpes simplex virus (HSV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), influenza A virus, and influenza B virus.
    Fórmula:C10H12N5Na2O7P
    Pureza:Min. 98 Area-%
    Cor e Forma:Powder
    Peso molecular:391.18 g/mol

    Ref: 3D-NA10801

    25mg
    3.843,00€
    50mg
    5.723,00€
    100mg
    8.175,00€
  • 3’-b-C-Methylcytidine

    CAS:
    3’-b-C-Methylcytidine is a nucleoside analog that inhibits the viral enzyme reverse transcriptase and is used as an antiviral agent. 3’-b-C-Methylcytidine binds to DNA and prevents RNA synthesis, which is essential for viral replication. It has been shown to inhibit the growth of cultured cells from human breast cancer and melanoma, suggesting that it also has anticancer activity. 3’-b-C-Methylcytidine can be synthesized in high purity and at high yield using phosphoramidites. This nucleoside analog may be useful in clinical applications due to its ability to activate transcription, which may lead to novel therapeutic strategies.
    Pureza:Min. 95%

    Ref: 3D-MM163085

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  • BBQ-650-DT CEP

    CAS:
    BBQ-650-DT CEP is an antiviral compound that is a phosphoramidite derivative of cytidine. BBQ-650-DT CEP has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in vitro, and to inhibit tumor cell proliferation in vivo. BBQ-650-DT CEP also inhibits the synthesis of RNA and DNA, which may have anticancer properties. This compound has been shown to be active against leukemia cells, lymphoma cells, and various breast cancer cell lines. It has also been shown to induce apoptosis in leukemia cells.
    Fórmula:C76H89N12O15P
    Pureza:Min. 95%
    Peso molecular:1,441.6 g/mol

    Ref: 3D-FLB55446

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  • 2-Chloro-2',3'-O-isopropylideneadenosine

    CAS:
    2-Chloro-2',3'-O-isopropylideneadenosine is a novel, anti-cancer drug that inhibits the synthesis of DNA. It is a phosphoramidite monophosphate with a molecular weight of 288.08 g/mol and an empirical formula C6H12ClNO5PS. The chemical name for this compound is 2-chloro-N-(2,3-diisopropyl)adenine diphosphate. This product has not yet been approved by the FDA for use in humans or animals.
    Fórmula:C13H16ClN5O4
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:341.75 g/mol

    Ref: 3D-NC06329

    1g
    1.590,00€
    50mg
    245,00€
    100mg
    341,00€
    250mg
    586,00€
    500mg
    1.058,00€
  • Clofarabine

    CAS:
    Clofarabine is FDA-approved for treating relapsed or refractory acute lymphoblastic leukaemia (ALL) in children after at least two other types of treatment have failed
    Fórmula:C10H11ClFN5O3
    Pureza:Min. 98 Area-%
    Cor e Forma:White Off-White Powder
    Peso molecular:303.68 g/mol

    Ref: 3D-NA07154

    1g
    488,00€
    2g
    724,00€
    5g
    1.155,00€
    10g
    1.847,00€
    500mg
    286,00€
  • 3'-Deoxy-2'-O-methyladenosine

    CAS:

    3'-Deoxy-2'-O-methyladenosine is a nucleoside that has antiviral and anticancer activity. It is a novel chemical compound with a unique structure, which makes it highly reactive. 3'-Deoxy-2'-O-methyladenosine induces DNA synthesis and cell proliferation in cancer cells. It also inhibits the production of viral DNA and RNA in infected cells by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 3'-Deoxy-2'-O-methyladenosine can be used as an antiviral agent against herpes simplex virus type 1 (HSV1), herpes simplex virus type 2 (HSV2) and human cytomegalovirus (CMV).

    Fórmula:C11H15N5O3
    Pureza:Min. 95%
    Cor e Forma:Off-White Powder
    Peso molecular:265.27 g/mol

    Ref: 3D-ND08558

    10mg
    237,00€
    25mg
    445,00€
    50mg
    593,00€
    100mg
    939,00€
    250mg
    1.851,00€
  • 6-O-Methylinosine

    CAS:
    6-O-Methylinosine is a modified nucleoside that is used in the synthesis of recombinant proteins. It is synthesized from the reaction of methylphosphate and 6-O-methylguanosine. The phosphate group of the 6-O-methylguanosine molecule reacts with methylphosphate in an acid or neutral environment, while it reacts with phosphoric acid in a basic environment. This reaction can be monitored by measuring the amount of free phosphate groups present after the reaction. The rate of this reaction can be increased by increasing temperature and pH. 6-O-Methylinosine has been shown to have anticancer activity, which may be due to its ability to inhibit enzyme catalysis and modify DNA structure.
    Fórmula:C11H14N4O5
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:282.25 g/mol

    Ref: 3D-NM144751

    1g
    329,00€
    2g
    454,00€
    5g
    962,00€
    10g
    1.494,00€
  • 2'-O-(2-Methoxyethyl)uridine

    CAS:
    2'-O-(2-Methoxyethyl)uridine is a nucleoside analog that inhibits the synthesis of DNA, RNA and protein. It can be used as an antimetabolite to treat cancer and prevents tumor growth by interfering with cell division. 2'-O-(2-Methoxyethyl)uridine is often used in combination with other chemotherapeutic drugs. This drug is not active against bacteria and does not inhibit the growth of bacteria. The major disadvantage of this drug is its lack of efficacy against tumors, which may be due to the lack of penetration through the cell membrane or damage to DNA caused by radiation, abiotic factors, or malfunctioning enzymes. 2'-O-(2-Methoxyethyl)uridine has been shown to cause damage to cells by altering their metabolism and affecting the function of their mitochondria. Damage can cause cells to die through apoptosis or necrosis.
    Fórmula:C12H18N2O7
    Pureza:Min. 95 Area-%
    Cor e Forma:Powder
    Peso molecular:302.28 g/mol

    Ref: 3D-NM16314

    1g
    416,00€
    2g
    550,00€
    5g
    736,00€
    10g
    1.174,00€
    500mg
    258,00€
  • 6-Thioinosine

    CAS:

    6-Thioinosine is a nucleoside analog that is chemically related to 6-mercaptopurine. It inhibits the polymerase chain reaction and has been shown to inhibit aerobic metabolism in aerobacter aerogenes. It also inhibits the growth of hl-60 cells, which are derived from human leukemia cells. 6-Thioinosine has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. It also blocks the activity of certain receptors and has a disease activity against infectious diseases such as systemic candidiasis, bacterial endocarditis, and bowel disease.

    Fórmula:C10H12N4O4S
    Pureza:Min. 98 Area-%
    Cor e Forma:Powder
    Peso molecular:284.29 g/mol

    Ref: 3D-NT08808

    1g
    274,00€
    10g
    1.042,00€
    25g
    1.927,00€
    50g
    2.780,00€
    100g
    3.824,00€
  • 5-b-D-Ribofuranosyl-2(1H)-pyridinone

    CAS:
    5-b-D-Ribofuranosyl-2(1H)-pyridinone is a phosphoramidite that is used in the synthesis of DNA. It is also an antiviral and anticancer agent. 5-b-D-Ribofuranosyl-2(1H)-pyridinone may be modified to include deoxyribonucleosides or ribonucleosides, which are important for DNA synthesis. 5-b-D-Ribofuranosyl-2(1H)-pyridinone is a novel chemical compound with a high purity and quality. 5 b D Ribofuranosyl 2 1 H Pyridinone CAS No 188871 50 3 Activator monophosphate High purity High quality DNA Synthetic Deoxyribonucleosides Novel Modified Ribonuclesides Nucleosides
    Pureza:Min. 95%

    Ref: 3D-NR162871

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  • 5’-Deoxy-5’-iodo-2’-O-methyluridine

    CAS:

    5’-Deoxy-5’-iodo-2’-O-methyluridine is a nucleoside that is modified with the substitution of an iodine atom for a hydrogen atom on the 5′ carbon. It has antiviral and anticancer properties. The high purity and novel structure make this compound useful in DNA synthesis. This product can also be used as a phosphoramidite or deoxyribonucleoside building block in DNA synthesis.

    Pureza:Min. 95%

    Ref: 3D-ND163006

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  • 3'-O-Methyladenosine

    CAS:

    3'-O-Methyladenosine (3'OMeA) is a monomethylated adenosine that belongs to the group of nucleosides. It has been found to inhibit the activity of adenosine receptors, which are important for the regulation of blood pressure and central nervous system function. 3'OMeA also inhibits virus replication in human lymphocytes. 3'OMeA is synthesized by reaction with methylamine and purification by column chromatography. The molecule is a potential therapeutic target for HIV/AIDS, as it can be used as a specific agonist in order to block viral entry into cells.

    Fórmula:C11H15N5O4
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:281.27 g/mol

    Ref: 3D-NM03526

    1g
    1.408,00€
    50mg
    260,00€
    100mg
    445,00€
    250mg
    645,00€
    500mg
    934,00€
  • 5-Azacytidine 5'-monophosphate

    CAS:
    5-Azacytidine 5'-monophosphate (5-Aza-CMP) is a modified nucleoside that inhibits DNA synthesis by competitively inhibiting the incorporation of deoxycytidine 5'-triphosphate into DNA. It is used as an antiviral and anticancer agent. 5-Aza-CMP has been shown to inhibit the proliferation of human cancer cells in vitro, including T cell leukemia, lymphoma, breast cancer, and melanoma.
    Fórmula:C8H13N4O8P
    Pureza:Min. 95%
    Cor e Forma:White to off-white solid.
    Peso molecular:324.18 g/mol

    Ref: 3D-NA09600

    1mg
    258,00€
    2mg
    457,00€
    5mg
    849,00€
    10mg
    1.975,00€
    25mg
    4.156,00€
  • α-Thymidine

    CAS:

    a-Thymidine is a thymidylate analog that is used as an anti-HIV drug. It is the L-enantiomer of thymidine, which is a nucleoside base in DNA. The biological effects of a-thymidine are due to its ability to be incorporated into DNA and act as a competitive inhibitor of the enzyme protein synthesis. It also has been shown to have antiviral properties against herpes simplex virus type 1 and hepatitis B virus.

    Fórmula:C10H14N2O5
    Pureza:Min. 98 Area-%
    Cor e Forma:Powder
    Peso molecular:242.23 g/mol

    Ref: 3D-NT00283

    1g
    804,00€
    2g
    1.195,00€
    100mg
    226,00€
    250mg
    423,00€
    500mg
    562,00€
  • 2'-O-Methyladenosine-5'-triphosphate sodium salt - 100mM aqueous solution

    CAS:
    2'-O-Methyladenosine-5'-triphosphate sodium salt is a novel nucleoside phosphoramidite. It is an activator and it can be used in the synthesis of DNA and RNA. The compound has antiviral properties and has been shown to inhibit DNA replication, protein synthesis, and RNA transcription. The compound also inhibits the growth of cancer cells by inducing apoptosis.
    Fórmula:C11H18N5O13P3·xNa
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:521.21 g/mol

    Ref: 3D-NM157272

    5mg
    469,00€
    10mg
    800,00€
    25mg
    1.599,00€
    50mg
    2.832,00€
    2500µg
    312,00€
  • 1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)uracil

    CAS:
    1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)uracil is a synthetic antiviral agent that inhibits the activity of DNA and RNA polymerases. It also has anticancer properties. The compound is an analogue of 2'-deoxycytidine monophosphate (dCMP). This compound binds to the phosphate group of nucleoside triphosphates and prevents their incorporation into DNA or RNA. 1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy) -2′ fluoro -b D arabinofuranosyl) uracil has been shown to inhibit the growth of cancer cells in vitro.
    Pureza:Min. 95%

    Ref: 3D-NA162840

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  • 6-Amino-1-(2'-deoxy-a-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine


    6-Amino-1-(2'-deoxy-a-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine is a modified nucleoside that is an antiviral agent and anticancer drug. It inhibits viral replication by inhibiting the activity of DNA polymerase. 6-[Amino(2'-deoxyribofuranosyl)]-1-(2'-deoxyribofuranosyl)-4-methoxypyrazolo[3,4-d]pyrimidine has been shown to inhibit the growth of cancer cells without affecting healthy cells.
    Pureza:Min. 95%

    Ref: 3D-NA162964

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  • 3'-O-Aminoacetoxy-2'-deoxyadenosine


    amino functionalised nucleoside
    Fórmula:C13H22N6O3
    Pureza:Min. 98 Area-%
    Cor e Forma:Powder
    Peso molecular:310.36 g/mol

    Ref: 3D-NA180284

    1g
    1.686,00€
    50mg
    201,00€
    100mg
    338,00€
    500mg
    1.019,00€
  • N6-Benzoyl-7-deaza-2'-deoxy-7-iodoadenosine

    CAS:
    N6-Benzoyl-7-deaza-2'-deoxy-7-iodoadenosine is an antiviral compound that inhibits the synthesis of DNA and RNA. It is a synthetic, modified nucleoside with antiviral properties. The compound has been shown to be active against both animal and human tumor cells, as well as being effective in the treatment of viral infections.N6-Benzoyl-7-deaza-2'-deoxy-7-iodoadenosine is water soluble and biologically stable.
    Pureza:Min. 95%

    Ref: 3D-NB137597

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  • 1-(b-D-Xylofuranosyl)-2-thiouracil

    CAS:

    1-(b-D-Xylofuranosyl)-2-thiouracil is a synthetic nucleoside that inhibits viral and cancer cell growth. It is an analog of the natural nucleoside thymidine, with an extra oxygen atom at position 2. The molecule forms a monophosphate, which is converted to a diphosphate by phosphoramidate synthase. This diphosphate is then incorporated into DNA, where it inhibits the activity of DNA polymerase and deoxyribonucleases, leading to inhibition of DNA synthesis. 1-(b-D-Xylofuranosyl)-2-thiouracil also has antiviral properties as it can inhibit viral replication by blocking the incorporation of nucleotides into the growing DNA strand.

    Fórmula:C9H12N2O5S
    Pureza:Min. 95%
    Peso molecular:260.27 g/mol

    Ref: 3D-NX163071

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