Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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Cytidine 5'-monophosphate free acid
CAS:Cytidine 5'-monophosphate is a nucleotide that is important in the synthesis of DNA and RNA. It is a precursor to uridine monophosphate (UMP) and uridylic acid (UDP). Cytidine 5'-monophosphate has been found to inhibit the growth of antibiotic-resistant strains of bacteria, such as those resistant to ampicillin, chloramphenicol, tetracycline, kanamycin, and streptomycin. Cytidine 5'-monophosphate also has inhibitory properties against energy metabolism and protein oxidation in bowel disease. This nucleotide has been shown to increase the rate constant for polymerase chain reaction (PCR) by up to 10-fold.Fórmula:C9H14N3O8PPureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:323.2 g/mol2'-C-Methylguanosine 5'-diphosphate triethylammonium salt
2'-C-Methylguanosine 5'-diphosphate triethylammonium salt is a synthetic nucleotide analog for use in researchFórmula:C11H16N5O11P2·C18H45N3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:759.79 g/mol2-Methylmercapto-4-oxo-6-aminopyrimidine monohydrate
CAS:2-Methylmercapto-4-oxo-6-aminopyrimidine monohydrate is a chemical substance that is used as an anticancer and antiviral agent. It has been demonstrated to inhibit the proliferation of tumor cells in vitro and in vivo, and to deplete tumor cell lines of the enzyme ribonucleotide reductase, which is essential for DNA synthesis. The compound also inhibits the synthesis of viral nucleic acid. 2MMAP has a novel chemical structure that includes a methyl group attached to one nitrogen atom. This modification increases its affinity for DNA and RNA molecules by binding to the phosphate groups on these molecules.Fórmula:C5H7N3OS·H2OPureza:Min. 95%Cor e Forma:PowderPeso molecular:175.21 g/molE-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine
CAS:E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is a nucleoside that is a modified form of uridine. It is a nucleotide analog that inhibits the synthesis of DNA and RNA and can be used to treat cancer. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is an activator that activates the phosphoramidites in the synthesis of DNA and RNA. This drug can also be used as antiviral therapy for herpes simplex virus type 1, influenza virus, and HIV. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine has been shown to have anti-inflammatory properties by inhibiting prostaglandin synthesis.Fórmula:C13H16N2O7Pureza:Min. 95%Cor e Forma:White to off-white solid.Peso molecular:312.28 g/mol5'-O-tert-Butyldiphenylsilyl-7-deaza-2'-deoxy-7-iodoadenosine
5'-O-tert-Butyldiphenylsilyl-7-deaza-2'-deoxy-7-iodoadenosine is a novel synthetic nucleoside with antiviral and antitumor activities. It has been shown to inhibit the activity of the HIV virus by preventing DNA replication. 5'-O-tert-Butyldiphenylsilyl-7-deaza-2'-deoxy-7-iodoadenosine also inhibits the synthesis of RNA and proteins, which can lead to cell death. The compound's high purity and quality are ensured by its CAS number.Fórmula:C27H31IN4O3SiPureza:Min. 95 Area-%Cor e Forma:White Off-White PowderPeso molecular:614.55 g/mol2',5'-Dideoxyuridine
CAS:2',5'-Dideoxyuridine is a synthetic nucleoside analog derived from uridine, one of the four standard nucleosides found in RNA. It is chemically modified by the removal of hydroxyl (–OH) groups at the 2' and 5' positions of the sugar, altering its ability to participate in RNA or DNA chain formation.
Fórmula:C9H12N2O4Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:212.21 g/mol2’,3’-Bis-O-tert-butyldimethylsilyl-5’-deoxy-4’,5’-Didehydrouridine
CAS:2’,3’-Bis-O-tert-butyldimethylsilyl-5’-deoxy-4’,5’-Didehydrouridine is a phosphoramidite that is used in the synthesis of DNA, RNA and nucleotide analogues. It has antiviral and antitumor properties and can be used for the treatment of leukemia. 2’,3’-Bis-O-tert-butyldimethylsilyl-5’-deoxyuridine is an activator for ribonucleotides and deoxyribonucleotides. It also has anticancer properties due to its ability to inhibit DNA replication, which may lead to apoptosis or cell death.Pureza:Min. 95%3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine
CAS:3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine is an antiviral drug. It is a modified nucleoside with phosphoramidite and azido groups. This product can be used as an activator for DNA synthesis, in anticancer drug development, as well as in the treatment of HIV. 3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine has been shown to inhibit the growth of human tumor cells by inhibiting protein synthesis and enhancing the production of reactive oxygen species (ROS). It also inhibits the activity of ribonucleotide reductase, which is a critical enzyme for DNA synthesis.Pureza:Min. 95%Inosine 5'-diphosphate disodium salt
CAS:Inosine-5'-diphosphate disodium salt (IDPS) is a nitro compound that is used in the synthesis of antibacterial drugs. It is also used in the production of polymers and as a precursor to other organic compounds. IDPS has been shown to have antibacterial activity against halogeno bacteria, such as buprestidae, and many Gram-positive bacteria, including encapsulated strains. IDPS has been shown to be effective against both damaged cells and healthy cells in culture. The mechanism of action may involve inhibition of protein synthesis by blocking the ribosomes or by interfering with DNA replication. This drug also inhibits growth rate of japonica rice and heterocycles.Fórmula:C10H12N4Na2O11P2Pureza:Min. 90.0 Area-%Cor e Forma:White PowderPeso molecular:472.15 g/molCyclopentenyl cytosine 5'-triphosphate sodium salt
Cyclopentenyl cytosine 5'-triphosphate sodium salt is a synthetic, activator diphosphate. It is used as a phosphoramidite in the synthesis of DNA and RNA. Cyclopentenyl cytosine 5'-triphosphate sodium salt has been shown to have anticancer and antiviral properties.Pureza:Min. 95%N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite
CAS:N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite is a novel nucleoside analogue with antiviral and anticancer potential. It is a modified nucleoside that contains an acetyl group at the 4' position. The 3'-OH group has been replaced by a tertiary butyldimethylsilyl group, which renders the compound resistant to deamination by nucleases. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite also shows high purity and high quality.Fórmula:C47H64N5O9PSiPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:902.11 g/molFurano-dt cep
CAS:Furano-dt cep is a novel antiviral drug that has been shown to inhibit the production of viral nucleic acid and to activate the immune system. Furano-dt cep is a phosphoramidite compound that is synthesized from ribonucleosides and deoxyribonucleosides, which are modified with 2,2-dithiobis(propionitrile). Furano-dt cep binds to the 5'-terminal phosphate group on the DNA strand, preventing RNA synthesis. Furano-dt cep also inhibits tumor growth by causing cell death through apoptosis.
Fórmula:C42H49N4O8PPureza:Min. 95%Peso molecular:768.8 g/mol1-Methyl-2'-O-methylinosine
CAS:1-Methyl-2'-O-methylinosine is a nucleoside that is naturally found in RNA. It is the methylated form of inosine, which is a nonessential amino acid and purine nucleotide. 1-Methyl-2'-O-methylinosine's chemical name is β--D--ribofuranosyl-(1'→2')--N--(6-fluoro-3-indoxyl)glycinamide monohydrochloride. This nucleoside has been researched for its potential use as an indexing tool for phylogenetic research of DNA and RNA. 1-Methyl-2'-O-methylinosine has also been shown to be structurally similar to other nucleic acids and has been classified as a nucleoside.Fórmula:C12H16N4O5Pureza:Min. 95%Peso molecular:296.28 g/molAdenosine 5′-phosphosulfate triethylammonium salt
Adenosine 5′-phosphosulfate triethylammonium salt serves as a donor of sulfate groups in biochemical processes, such as in the synthesis of sulfate esters. The triethylammonium salt form improves the solubility and stability of the compound, making it useful in laboratory applications involving enzymatic assays and the synthesis of sulfated biomolecules.
Fórmula:C10H14N5O10PS·xC6H15NPureza:Min. 98.0 Area-%Cor e Forma:PowderPeso molecular:427.29 g/mol8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt
CAS:8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt (8-CPT-cAMP) is a cyclic nucleotide that activates adenyl cyclase, which increases intracellular levels of the second messenger cAMP. It also inhibits P2Y receptors and other ion channels. 8-CPT-cAMP has been shown to be effective in activating cells expressing the enzyme camp levels, such as those found in heart muscle cells. This drug is used clinically to lower blood pressure, as it has been shown to activate amp-activated protein kinase and calcium chelator. 8-CPT-cAMP may have clinical applications for the treatment of cancer due to its ability to induce cell cycle arrest and apoptosis.Fórmula:C17H16ClN5O6PS·NaPureza:Min. 95%Cor e Forma:PowderPeso molecular:507.82 g/mol5'-Azido-5'-deoxythymidine
CAS:5'-Azido-5'-deoxythymidine is a synthetic analogue of thymidine. The compound has been synthesised and fluorescently labelled with ferrocene. 5'-Azido-5'-deoxythymidine is not cytotoxic to cancer cells, but it is shown to be an effective inhibitor of DNA synthesis by binding to the enzyme DNA polymerase. This causes a decrease in the rate of DNA synthesis and thus inhibits cancer cell growth.Fórmula:C10H13N5O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:267.24 g/mol3'-Azido-N4-benzoyl-2',3'-dideoxycytidine
CAS:3'-Azido-N4-benzoyl-2',3'-dideoxycytidine is a novel nucleoside analog with antiviral and anticancer activities. It is used for the treatment of HIV, hepatitis B and C, herpes, and influenza. 3'-Azido-N4-benzoyl-2',3'-dideoxycytidine has been shown to inhibit the proliferation of cells in culture and to induce apoptosis in various cancer cell lines.
The synthesis of 3'-azido-N4-benzoyl-2',3'-dideoxycytidine starts with the condensation of 4-(hydroxymethyl)phenylacetic acid (1) with 2,6-dichloroisonicotinic acid chloride (2) in the presence of triethylamine to give 4-(hydroxymethyl)phenylacetic acid chloride (3). The N4 benzoylFórmula:C16H16N6O4Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:356.34 g/molN3-Methyl-2’-O-(2-methoxyethyl)uridine
CAS:N3-Methyl-2’-O-(2-methoxyethyl)uridine is a modified nucleoside that is synthesized from deoxyribonucleosides and ribonucleosides. It has antiviral, anticancer, and antifungal properties. N3-Methyl-2’-O-(2-methoxyethyl)uridine has been shown to be an effective inhibitor of HIV replication in vitro and in vivo. This drug also inhibits the growth of human cancer cells in vitro and has been shown to be active against breast cancer cells. N3-Methyl-2’-O-(2-methoxyethyl)uridine is phosphorylated by cellular enzymes to form its active form, which binds to the viral reverse transcriptase enzyme and prevents DNA synthesis.Fórmula:C13H20N2O7Pureza:Min. 95%Peso molecular:316.31 g/mol1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)thymine
CAS:1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)thymine is a chemically modified nucleoside analog. This compound contains a thymine base, a 2'-fluoro-β-D-arabinofuranose sugar, which alters biological stability and function and benzoyl protecting groups at the 3' and 5' positions, commonly used in nucleoside synthesis to control selective modifications.Fórmula:C24H21FN2O7Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:468.43 g/molAdenosine 5'-O-(3-thiotriphosphate), BODIPY FL thioester sodium salt - 5mM buffered aqueous solution
Adenosine 5'-O-(3-thiotriphosphate), BODIPY FL thioester sodium salt - 5mM buffered aqueous solution is a novel nucleoside that is synthesized from the corresponding phosphoramidites. This compound is an activator of DNA synthesis in mammalian cells and a potent inhibitor of viral replication. It has antiviral activity against HIV, herpes, and influenza viruses. The molecule can be modified to include different substituents such as fluoro, bromo, or chloro groups and has been shown to have anticancer activity.Fórmula:C24H27BF2N8Na3O13P3SPureza:Min. 95%Peso molecular:878.28 g/mol
