Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydroxyamino-1H-pyrazolo[3,4-d]pyrimidine
6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydroxyamino-1H-pyrazolo[3,4-d]pyrimidine is a modified nucleoside with antiviral and anticancer properties. It is an activator of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydroxyamino-1H pyrazolo[3,4 d]pyrimidine can be used in the synthesis of phosphoramidites for DNA synthesis and for the production of monophosphate nucleotides. The compound has been shown to inhibit the growth of cells in culture that are resistant to other antiinfectives such as erythromycin and chloramphenicol.Pureza:Min. 95%2'-O-Methyl-5-methylcytidine
CAS:2'-O-Methyl-5-methylcytidine is a nucleoside that is categorized as a modified nucleic acid. It is structurally similar to cytidine, but has an additional methyl group. 2'-O-Methyl-5-methylcytidine stabilizes the conformational structure of nucleic acids and can be used to regulate the activity of enzymes. This modified nucleoside has been shown to have thermophilic characteristics when it interacts with human cells. The stability of 2'-O-Methyl-5-methylcytidine increases with increasing temperature, making it possible for this molecule to regulate gene expression in organisms that live at high temperatures.Fórmula:C11H17N3O5Pureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:271.27 g/mol3’-Deoxy-3’-fluoro-N6-hydroxyadenosine
CAS:3’-Deoxy-3’-fluoro-N6-hydroxyadenosine (3'-DF) is an antiviral nucleoside that inhibits viral DNA synthesis and has shown cytotoxic effects in human cancer cells. 3'-DF is a novel chemical compound that was first synthesized in 1994. It is a nucleotide analog that is structurally related to adenosine, with the exception of the fluoro atom at position 6 on the ribose sugar. 3'-DF inhibits DNA polymerase and RNA polymerase by competitively binding to the ribonucleotide reductase enzyme, inhibiting the production of new RNA and DNA molecules. This compound also has been shown to inhibit protein synthesis in cancer cells without affecting normal cells.Pureza:Min. 95%5-Fluoro-4’-C-methyluridine
CAS:5-Fluoro-4’-C-methyluridine is a novel antiviral agent that is structurally related to the nucleoside analogue cytidine. It has been shown to be an activator of DNA polymerase, which may contribute to its antiviral activity. 5-Fluoro-4’-C-methyluridine has been shown to inhibit the growth of cancer cells by modifying the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). 5-Fluoro-4’-C-methyluridine has also been shown to have anticancer effects, as it inhibits cell proliferation and induces apoptosis.Pureza:Min. 95%Isocytidine triphosphate triethylamine
CAS:Isocytidine triphosphate triethylamine salt is a nucleoside that has been modified to include an amino group. It is a monophosphate, which means it contains one phosphate group. Isocytidine triphosphate triethylamine salt has shown anticancer properties as it inhibits the synthesis of DNA and RNA. This compound also prevents the activation of transcription factors, such as NF-κB, that are important in cancer cell proliferation.Fórmula:C9H16N3O14P3•(C6H15N)xPureza:Min. 95%Cor e Forma:PowderPeso molecular:483.15 g/mol2-Amino-6-chloro-9-(b-D-ribofuranosyl)purine
CAS:Intermediate in the synthesis of nelarabineFórmula:C10H12ClN5O4Pureza:Min. 97 Area-%Cor e Forma:Off-White PowderPeso molecular:301.69 g/mol5'-O-MMT-thymidine 3'-CE phosphoramidite
CAS:5'-O-MMT-thymidine 3'-CE phosphoramidite is a novel anticancer drug that is modified from the natural nucleoside thymidine. It has been shown to inhibit the activity of DNA polymerase, preventing DNA synthesis and replication. It also inhibits viral DNA replication, including HIV and herpes simplex virus type-1 (HSV-1). 5'-O-MMT-thymidine 3'-CE phosphoramidite has antiviral properties against HIV and HSV-1. This nucleoside is synthesized by reacting 5'-O-methyl cytidylic acid with an activated phosphite in the presence of triethylamine in dichloromethane. The product is purified by column chromatography on silica gel and recrystallization from acetonitrile.
Fórmula:C39H47N4O7PPureza:Min. 95%Peso molecular:714.81 g/mol3'-O-Propargyluridine
CAS:3'-O-Propargyluridine is a synthetic nucleoside with an alkyne functional handle on the 3'-position of the sugarFórmula:C12H14N2O6Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:282.25 g/molN2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite
N2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is a novel ribonucleotide with high purity and high quality. It is an activator of DNA synthesis and can be used in the synthesis of DNA, monophosphate, and diphosphate. N2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is used for the preparation of anticancer drugs, antiviral agents, and other nucleosides.Fórmula:C44H55N8O8PPureza:Min. 95%Cor e Forma:White PowderPeso molecular:854.95 g/molUridine-5'-triphosphate trisodium salt
CAS:P2Y receptor agonist; precursor in RNA biosynthesisÂFórmula:C9H12N2Na3O15P3Pureza:(31P Nmr) Min. 95 Area-%Cor e Forma:White PowderPeso molecular:550.09 g/molN6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite
CAS:N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite is an antiviral nucleoside phosphoramidite that is used in the synthesis of DNA. It has been shown to have antiviral activity against HIV and herpes, as well as anticancer effects. It also has high purity, being a novel synthetic nucleoside with a CAS number. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite is synthesized using novel methods. The synthesis process includes activation with diphosphate, DNA, and Novel nucleosides, which are high quality and modified.Fórmula:C53H66N7O8PSiPureza:Min. 95%Cor e Forma:PowderPeso molecular:988.19 g/molN6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine
CAS:N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine is a nucleoside that can be used in the synthesis of oligomers. It is a synthetic nucleoside with an absorption maximum at 410 nm and emission maximum at 522 nm. This compound has been shown to be efficient in the synthesis of phosphoramidites and ligands, as well as in rna synthesis and modifications. N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine may inhibit bacterial growth by binding to the ribosome, preventing protein synthesis.
Fórmula:C44H49N5O7SiPureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:787.97 g/mol3’-b-Amino-2’,3-dideoxy uridine
CAS:3’-b-Amino-2’,3-dideoxy uridine is an activator nucleoside that is a novel therapeutic agent for viral infections and cancer. It has antiviral activity against herpes simplex virus type 1 (HSV-1) and cytomegalovirus (CMV), as well as anticancer activity against human breast adenocarcinoma cells. 3’-b-Amino-2’,3-dideoxy uridine is a modified nucleoside with antiviral and anticancer properties. This drug has been shown to inhibit HSV-1 replication by interfering with the synthesis of viral DNA. 3’-b-Amino-2’,3-dideoxy uridine also inhibits the proliferation of human breast adenocarcinoma cells by inhibiting ribonucleotide reductase.Fórmula:C9H13N3O4Pureza:Min. 95%Peso molecular:227.22 g/mol2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-methyluridine
CAS:2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-methyluridine is a nucleoside that is synthesized from 2’,3’,5’triphosphate and 5-methyluridine. It has been shown to be an activator of monophosphate synthesis in cells and to have anti-cancer properties. This compound is used in the synthesis of phosphoramidites for DNA sequencing.Pureza:Min. 95%N4-Acetylcytidine
CAS:N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.Fórmula:C11H15N3O6Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:285.25 g/mol3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-5-trifluoromethyl-arabinouridine
CAS:Please enquire for more information about 3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-5-trifluoromethyl-arabinouridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePureza:Min. 95%1-(Arabinofuranosyl)-5-azidomethyluracil
CAS:1-(Arabinofuranosyl)-5-azidomethyluracil (AFAU) is a novel nucleoside that is synthesized by the reaction of 5-azido-1-(2'-deoxyribofuranosyl) uracil with phosphoramidite. The synthesis of this nucleoside has been used as a model for the synthesis of other deoxyribonucleosides. AFAU is an activator of ribonucleotide reductase and has shown activity against DNA and RNA viruses, such as influenza virus, herpes simplex virus type 1, and human immunodeficiency virus type 1.Pureza:Min. 95%9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine
9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine is a novel nucleoside that has been synthesized by the phosphoramidite method. It is a monophosphate, which can be activated to yield an anticancer agent. 9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine is chemically modified with a silyl group at the 5' position of the sugar moiety and a tertiary butyldiphenylsilyl group at the 2' position of the sugar moiety. It has been shown to inhibit DNA synthesis and viral replication, as well as to have antiangiogenic activity.Pureza:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite is a modified nucleoside that is synthesized by the reaction of 2'-deoxycytidine with bis(2,4,6-trichlorophenyl)carbonate in the presence of a base. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3 methylcytidine 3'-CE phosphoramidite has been shown to have anticancer activity and is used as an activator in the synthesis of oligonucleotides. This product is available as a white powder and can be used for research purposes only.Pureza:Min. 95%2'-Deoxy-5-(2-iodoethyl)uridine
CAS:2'-Deoxy-5-(2-iodoethyl)uridine is a nucleoside analog with antiviral and anticancer activity. It has been shown to be an activator of DNA replication, as well as inhibiting the synthesis of deoxyribonucleotides. This drug also has a novel structure that is modified from the natural nucleosides found in DNA and RNA. 2'-Deoxy-5-(2-iodoethyl)uridine can be synthesized using phosphoramidites, which are activated by iodine and sulfurizing agents. The purity of this compound is high and it is available at high quality.Pureza:Min. 95%
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