Oligonucleotídeos
Os oligonucleotídeos são sequências curtas de nucleotídeos, tipicamente variando de 2 a 25 bases, que são sintetizadas para uma variedade de aplicações de pesquisa e terapêuticas. Eles desempenham papéis cruciais na biologia molecular, servindo como iniciadores para amplificação de DNA, sondas para detectar sequências específicas e agentes para silenciamento e regulação gênica. Os oligonucleotídeos são amplamente utilizados em técnicas como PCR, qPCR, sequenciamento e terapia antissentido. Na CymitQuimica, oferecemos uma ampla seleção de oligonucleotídeos de alta qualidade para apoiar sua pesquisa em genética, biotecnologia e diagnósticos médicos.
Foram encontrados 202 produtos para "Oligonucleotídeos".
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ODN 2336
CAS:ODN 2336: A-Class CpG ODN, potent TLR9 agonist, boosts IFN-α, IP-10, IL-18 mRNA, vaccine adjuvant.Cor e Forma:LiquidPeso molecular:6761.7Tofersen sodium
CAS:Tofersen sodium, an antisense oligonucleotide, facilitates RNase H-dependent degradation of superoxide dismutase 1 (SOD1) mRNA, thereby decreasing the production of SOD1 protein. It is applicable in amyotrophic lateral sclerosis (ALS) research.Fórmula:C230H298N72Na19O123P19S15Peso molecular:7546.00Alicaforsen sodium
CAS:Alicaforsen sodium is a 20-base antisense oligonucleotide that inhibits ICAM-1, key in leukocyte migration to inflammation sites.Cor e Forma:SolidBaliforsen
CAS:Baliforsen, a 16-nucleotide antisense oligonucleotide, is crafted to specifically target the mRNA of myotonic dystrophy protein kinase (DMPK) for the study of myotonic dystrophy.Cor e Forma:SolidPeso molecular:5616Monarsen
CAS:Monarsen (EN101) is a 20-base antisense oligo targeting the AChE gene, used in researching autoimmune myasthenia gravis.Cor e Forma:SolidODN 6016
CAS:ODN 6016, a CpG-A oligonucleotide, boosts IFN-α, aiding HIV-1 related immunodeficiency research. Sequence: T-sp-C-G-A-C-G-T-C-G-T-G-G-sp-G-sp-G-sp-G.Cor e Forma:LiquidRGLS4326
CAS:RGLS4326: miR-17 inhibitor, targets ADPKD; effective in HeLa cells with EC50 of 28.3 nM.Fórmula:C95H115F3N32O51P8S8Cor e Forma:LiquidPeso molecular:3082.4Trecovirsen
CAS:Trecovirsen (GEM91) is a 25-mer antisense phosphorothioate oligonucleotide that targets the gag site of the HIV gene.Cor e Forma:SolidRovanersen sodium
CAS:Rovanersen sodium, an antisense oligonucleotide, selectively binds to mutated mRNA copies of the huntington (HTT) gene while sparing healthy HTT mRNA, effectively inhibiting the synthesis of defective Huntingtin protein. This compound is utilized in research on Huntington's disease.Fórmula:C202H240N82Na19O111P19S13Peso molecular:7034.70Vupanorsen
CAS:Vupanorsen, an N-acetyl galactosamine-conjugated antisense oligonucleotide, inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis and reduces triglycerides and atherogenic lipoproteins.Fórmula:C296H434N86O152P20S13Peso molecular:8659.99962Custirsen
CAS:Custirsen blocks clusterin, enhancing chemo by reducing cancer cell resistance.Cor e Forma:SolidPeso molecular:7346Vupanorsen sodium
CAS:Vupanorsen (sodium) is an N-acetyl galactosamine-conjugated antisense oligonucleotide designed to inhibit the synthesis of Angiopoietin-like 3 (ANGPTL3) protein. This compound effectively reduces levels of triglycerides and atherogenic lipoproteins.Fórmula:C296H414N86Na20O15P20S13Peso molecular:9105.04ODN 24987
CAS:ODN 24987: Guanine-modified TLR9 inhibitor, blocks IL-6/IFN-α, useful in immune research. Sequence: 5’-CCTGGC-c7GGGG-3’.Cor e Forma:LiquidPeso molecular:3229.6Cimdelirsen
CAS:Cimdelirsen: novel hepatic ASO to lower GH receptor production and IGF-1 in acromegaly.Cor e Forma:SolidTadnersen
CAS:Tadnersen (BIIB078) is an ASO targeting specific C9ORF72 transcript variants with expansion.Cor e Forma:LiquidATL 1102
CAS:ATL 1102 is a novel second-generation antisense oligonucleotide to CD49d mRNACor e Forma:SolidAZD8233
CAS:AZD8233 is a liver-targeting antisense oligonucleotide that inhibits the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9). By reducing PCSK9 levels, AZD8233 increases the availability of LDL receptors, facilitating the clearance of LDL from the bloodstream and consequently reducing LDL-C levels.Cimdelirsen sodium
CAS:Cimdelirsen: novel hepatic-targeted drug to lower GHr synthesis & IGF-1 in acromegaly by inhibiting GH excess.Fórmula:C296H415N83Na20O152P20S15Cor e Forma:SolidPeso molecular:9128.16Drisapersen
CAS:Drisapersen, an antisense oligonucleotide, facilitates exon 51 skipping in dystrophin pre-mRNA splicing, enabling the production of partially functional dystrophin in Duchenne muscular dystrophy (DMD) patients with suitable mutations.Cor e Forma:SolidPeso molecular:6978Cobomarsen
CAS:Cobomarsen (MRG-106) inhibits miR-155, affecting JAK/STAT, MAPK/ERK, PI3K/AKT, and used in B-cell lymphoma research.Cor e Forma:Liquid
