Anti-inflamatórios não esteróides (AINEs)

<p>Applications A new anti-inflammatory drug. Effect of SAS 650 (Furofenac) on malondialdehyde production by platelets.<br>References Bertoli, D., et al.: Int. J. Tissue Reactions, 2, 217 (1980),<br></p>

<p>Applications AHR 10240 Dimer is a dimer of 7-(4-Bromobenzoyl)-1,3-dihydro-2H-indol-2-one (B680190); a cyclic metabolite of Bromfenac (B678550).<br>References Osman, M.A. et al.: J. Chrom. Biomed. Appl., 489, 452 (1989); Isaka, M. et al.: Yakub. Dot., 14, 32 (1999)<br></p>

<p>Impurity Fluticasone EP Impurity D<br>Applications Ticabesone Propionate is an impurity of Fluticasone, an antiallergic, anti-asthmatic and anti-inflammatory agent.<br>References Marrero-Ponce, Y., et al.: Europ. J. Med. Chem., 46, 5736 (2011); Dalvi, P., et al.: J. Chem., 20, 187 (2008);<br></p>

<p>Applications 4-Fluorobenzonitrile-d4 is the labelled version of fluorobenzonitrile, a compound with industrial applications from solar cells to medicinal application as an anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Heilman, W.P. et al.: J. Med. Chem., 21, 906 (1978); Woo, S. et al.: J. Nano. Opto., 6, 338 (2011);<br></p>

<p>Applications Forsythoside A is used as an antiinflammatory agent in traditional Chinese medicine.<br>References Li, H. et al.: Phytother. Res., 25, 338 (2011);<br></p>

<p>Applications Sulforaphene is an extract from the seeds of Raphanus sativus and displays anti-inflammatory and anti-cancer activity.<br>References Kim, K. et al.: J. Ethnopharmacol., 151, 503 (2014);<br></p>

<p>Applications Intermediate for the synthesis of 2-Hydroxymethyl Loratadine.<br>References Cerrada, V., et al.: ARKIVOC, 9, 200 (2005).<br></p>

<p>Applications Intermediate for the synthesis of 2-Hydroxymethyl Loratadine.<br>References Cerrada, V., et al.: ARKIVOC, 9, 200 (2005).<br></p>

<p>Codeine Impurity F is a biochemical that is an impurity of codeine. Codeine Impurity F is a byproduct of the enzymatic reaction with morphine and the bacterial strain Pseudomonas putida. Codeine Impurity F has been shown to inhibit the growth of gram-negative bacteria, including Escherichia coli and Salmonella enterica, by binding to cellular membranes and inhibiting their function. It also binds to RNA in vitro and prevents translation of mRNA from its ribosome complex. The hydroxyl group on Codeine Impurity F binds to aluminium ions, which may interfere with the absorption of other drugs such as ampicillin or tetracycline. This impurity has been shown to have an effect on biological products such as immunoglobulins and albumin.</p>

<p>Apocodeine hydrochloride is a natural product that is used in the treatment of cancer. It has been shown to have antiproliferative effects on cho-k1 cells, which are human colon carcinoma cells. Apocodeine hydrochloride also inhibits the production of dopamine in rat brain and has been shown to inhibit bromocriptine-induced prolactin release from rat pituitary cells in vitro. Apocodeine hydrochloride has been extensively studied in epidemiological studies and has been found to be effective against cancer, with no adverse side effects.</p>

<p>Alfentanil is an opioid analgesic that is used for the treatment of severe or acute pain. It is a potent synthetic analog of fentanyl, which is an opioid analgesic that is used for the treatment of short-term (acute) and long-term (chronic) pain. Alfentanil has been shown to have a high affinity for α1-acid glycoprotein, which has been associated with drug interactions and blood sampling. Alfentanil also has chemical stability in experimental models and does not interact with nonsteroidal anti-inflammatory drugs. This drug may have a matrix effect on the concentration of cortisol in the blood.</p>

<p>Descyclopropyl abacavir is a synthetic prodrug form of the antiviral drug abacavir, which is used to treat HIV infection. It is metabolized by amine oxidases and, as such, has been shown to be a potent inhibitor of these enzymes. Descyclopropyl abacavir has also been shown to have herbicidal properties against control weeds and glyphosate-resistant weeds.</p>

<p>Oxymorphone is a potent synthetic opioid analgesic with a short duration of action. It is a prodrug that has to be metabolized in the liver by cytochrome P450 enzymes for activation. The 6-hydroxy metabolite is more potent than oxymorphone itself and has been shown to have antinociceptive properties in mice. Oxymorphone is used in cancer patients as an oral dosage form, which may be administered with or without food. It has been shown that the albumin concentration influences the pharmacokinetics of oxymorphone and its metabolites. This drug also has immunomodulatory effects and can cause adverse events such as hypersensitivity reactions, nausea, vomiting, or constipation.</p>

<p>(-)-cis-Pentazocine is a kappa-opioid receptor agonist that has been used for the treatment of pain, cough, and diarrhea. It is also used to treat withdrawal symptoms in those who are addicted to other narcotic drugs. The drug binds to the κ-opioid receptors and activates G protein coupled receptors. When this occurs, it inhibits the release of neurotransmitters from nerve cells in the brain, which reduces pain and causes sedation. Pentazocine can cause side effects such as dizziness, constipation, nausea, vomiting, headache, blurred vision, anxiety and depression. These side effects are more common with high doses or when pentazocine is taken with other drugs that have similar effects.</p>

<p>Please enquire for more information about Ibuprofen Sorbitol Ester - (Mixture of Diastereomers) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6-O-Methyl codeine is a drug that belongs to the class of opioid analgesics. It is used to treat severe pain and coughing in patients with infectious diseases, such as pneumonia or bronchitis. 6-O-Methyl codeine may be administered by mouth, intravenously, or intramuscularly. The mechanism of action of this drug is not fully understood, but it has been shown to decrease respiratory rate in some animal studies. 6-O-Methyl codeine also has an effect on the central nervous system and may cause dizziness, drowsiness, nausea, vomiting and constipation. This drug is metabolized through oxidative reactions with oxygenated molecules like fluorine or hydrogenated aromatic hydrocarbons. 6-O-Methyl codeine is a prodrug that can be converted into morphine following cleavage by liver enzymes.</p>

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