Antraciclinas
As antraciclinas são uma classe de potentes antibióticos antitumorais amplamente utilizados na quimioterapia do câncer. Esses compostos funcionam intercalando-se no DNA, interrompendo a função da topoisomerase II e impedindo a replicação das células cancerosas. As antraciclinas são particularmente eficazes contra uma ampla gama de cânceres, incluindo leucemias, linfomas e câncer de mama. No entanto, seu uso é muitas vezes limitado pela cardiotoxicidade, tornando a pesquisa de formulações mais seguras e eficazes uma área de foco importante. Na CymitQuimica, oferecemos uma seleção de antraciclinas para apoiar sua pesquisa em oncologia, desenvolvimento de fármacos e terapia do câncer.
Foram encontrados 175 produtos para "Antraciclinas".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Mitoxantrone (2-hydroxyethyl)piperazine impurity
CAS:Mitoxantrone is an anticancer drug that is used to treat various types of cancer. Mitoxantrone is a prodrug, which means it needs to be metabolized by the body to become active. The main metabolic pathway for mitoxantrone involves hydrolysis of the 2-hydroxyethyl piperazine impurity and formation of N-desmethylmitoxantrone, which is a metabolite that has been found to be more potent than the parent compound in inhibiting DNA synthesis. This impurity standard is used as a reference substance for quality control purposes during drug development. Mitoxantrone can also be synthesized with high purity and custom synthesis services are available upon request.Fórmula:C22H26N4O6Pureza:Min. 95%Cor e Forma:Brown PowderPeso molecular:442.47 g/molDoxorubicin impurity
CAS:Doxorubicin is an organic compound that belongs to the class of polycyclic aromatic hydrocarbons. It is used as a cancer therapy, primarily in the treatment of breast cancer. The chemical sensing of impurities in doxorubicin can be done using phase transfer methods. The quantification of these impurities can be done using high-performance liquid chromatography (HPLC) or gas chromatography (GC).Fórmula:C26H27NO11Pureza:Min. 90 Area-%Cor e Forma:Red PowderPeso molecular:529.49 g/molKarminomycin Hydrochloride
CAS:Applications Karminomycin Hydrochloride is an antibiotic that potently kills human tumor cells and their multidrug resistant variants. Highly active quinone-containing anticancer drugs. A new anthracycline antineoplastic antibiotic.
References Tevyashova, A. N., et al.: J. Antibiot., 57, 143 (2004); Bachur, N. R., et al.: Cancer Res., 38, 1745 (1978); Brazhnikova, M. G., et al.: J. Antibiot., 27, 254 (1974)Fórmula:C26H27NO10·HClCor e Forma:NeatPeso molecular:549.9547,8,9,10-Dehydro Doxorubicinone (~70%)
CAS:Produto ControladoFórmula:C21H14O8Pureza:~70%Cor e Forma:NeatPeso molecular:394.33Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone
CAS:Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone is a research and development impurity standard for synthesis. It is a synthetic, high purity compound with a CAS number of 89991-52-6. The chemical is not found in nature and does not have any natural metabolites. Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone has been shown to be metabolized by the liver into various metabolites that have been identified through analysis of urine samples. The metabolite of des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone may be used as an analytical standard for HPLC methods.Fórmula:C18H19N3O5Pureza:Min. 95%Peso molecular:357.36 g/molDoxorubicin Impurity 15
CAS:Doxorubicin impurity 15 is a natural product that is used as an analytical reference standard in pharmacopoeia. It has been synthesized for use in drug development and research and development, and is available as a high-purity HPLC standard. Doxorubicin impurity 15 has a CAS number of 131086-18-5.
Fórmula:C31H38BrNO11Pureza:Min. 95%Peso molecular:680.54 g/molDoxorubicin Imp B HBr salt
CAS:Doxorubicin Imp B HBr salt is a drug product that is custom synthesized for research and development. It's high purity, analytical, and natural are well suited for pharmacopoeia, drug development, and niche. Doxorubicin Imp B HBr salt has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The CAS No. 148218-14-8 is an impurity standard that can be used in HPLC analysis to determine the purity of Doxorubicin Imp B HBr salt.Fórmula:C29H34BrNO11BrHPureza:Min. 95%Peso molecular:733.4 g/molEpirubicin
CAS:Epirubicin is a Topoisomerase II inhibitor and anthracycline antibiotic used in cancer chemotherapy research.Fórmula:C27H29NO11Pureza:99.82%Cor e Forma:Red SolidPeso molecular:543.52Doxorubicin Dimer Impurity-1
Doxorubicin Dimer Impurity-1 is a drug product that is used as an HPLC standard. It is a metabolite of doxorubicin and has been shown to inhibit DNA synthesis in vitro. This impurity has been detected in the drug product using HPLC, and the purity of this impurity is greater than 98%. Doxorubicin Dimer Impurity-1 is a synthetic compound that has not been found in natural sources. It has been shown to be metabolized by human enzymes, such as esterases, glucuronidases, glutathione reductase, cytochrome P450 enzymes, and glucuronic acid conjugates. Doxorubicin Dimer Impurity-1 may also have anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.Fórmula:C54H56N2O21Pureza:Min. 95%Peso molecular:1,069.02 g/molRef: 4Z-D-3467
Produto descontinuadoRef: 4Z-D-3440
Produto descontinuadoRef: 4Z-D-3416
Produto descontinuadoRef: 4Z-D-3490
Produto descontinuadoRef: 4Z-M-088018
Produto descontinuadoRef: 4Z-D-3437
Produto descontinuadoRef: 4Z-I-055014
Produto descontinuadoRef: 4Z-I-055019
Produto descontinuadoRef: 4Z-D-3479
Produto descontinuadoRef: 4Z-D-3477
Produto descontinuado
![Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FID21105.webp&w=3840&q=75)
