Bloqueadores Alfa

<p>Alfuzosin EP Impurity F hydrochloride is a drug product that is used as an analytical standard for Alfuzosin hydrochloride. It is a natural, synthetic, and impurity standard that exhibits similar chromatographic properties to the API. The CAS number of this impurity is 19216-68-3. This product has a niche market because it is used in metabolism studies. It also exhibits high purity and pharmacopoeia grade quality.</p>

<p>Trazodone Impurity A is a drug product that is an impurity standard for Trazodone. It has been classified as a synthetic metabolite and is used in analytical research studies. Trazodone Impurity A has demonstrated niche applications in the pharmaceutical industry, including metabolism studies, pharmacopoeia requirements, and HPLC standards.</p>

<p>N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine hydrochloride is an impurity that can be found in some commercially available drugs. It is a metabolite of the drug N-(4-amino-6,7-dimethoxyquinazol-2-yl)propylenediamine and is used as a reference standard for HPLC analysis. This compound has been shown to have antiplatelet activities.</p>

<p>2-[3-[4-(3-Chloro-4-ethylphenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one is a research and development impurity standard. Impurities are the substances that are not intentionally added to the drug product but can be generated from the synthesis process or from the raw materials. This substance has been used as a synthetic intermediate in the production of other drugs and as an analytical reference for HPLC analysis. It is used to help develop new drugs by providing data about metabolites and possible toxic effects on humans.</p>

<p>10-Oxo mirtazapine is a metabolite of the antidepressant drug mirtazapine. It is an impurity in the HPLC standard for mirtazapine and has been shown to be pharmacologically active in animal models. 10-Oxo mirtazapine has also been found to be an impurity in other drugs, such as fluoxetine hydrochloride, but it is not known if it has any activity.</p>

<p>1,4-Bis[(tetrahydro-2-furanyl)carbonyl]-piperazine is a synthetic drug product. It is used as an analytical standard to help elucidate the metabolic pathway of drugs and their metabolites. This compound has been shown to be metabolized by various enzymes including CYP450, glutathione reductase, and esterases. It can also be synthesized from 1,4-dihydropyridine and 2-furancarboxaldehyde. The physical properties of 1,4-bis[(tetrahydro-2-furanyl)carbonyl]-piperazine are: white powder; mp 178°C; IR max 1710 cm−1 (CO); UV max 221 nm (EtOH). The impurities in this product are: 1-(2H)-Quinolinone (CAS No. 2467-94-1) which may have a maximum concentration</p>

<p>Alfuzosin is a drug used to treat the signs and symptoms of benign prostatic hyperplasia (BPH). The active form of alfuzosin, 1-alfuzosin, is a competitive antagonist at the α1-adrenoceptor. Alfuzosin minimizes the effects of BPH by reducing prostate size and increasing urine flow rate. It is also an impurity in N2-methyl alfuzosin hydrochloride (1:x), which has similar therapeutic uses as alfuzosin.</p>

<p>(S)-Terazosin is an active S-enantiomer of Terazosin.</p>

<p>(S)-Carvedilol is a non-selective β/α-1 blocker.It exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).</p>

<p>(R)-Carvedilol is a non-selective blocker of β/α-1. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).</p>

<p>Alfuzosin is a potent, selective, and long-acting α1A-adrenergic receptor antagonist. It is used to treat benign prostatic hyperplasia (BPH) in males. Alfuzosin is also used as an antihypertensive agent, for the treatment of pheochromocytoma, and for the treatment of benign prostatic hyperplasia in males. The hydrogenation of 2,3,4,5-tetradehydroalfuzosin to alfuzosin hydrochloride is performed by liquid hydrogenation or by hydrogenation on a palladium catalyst in a mixture of dimethylformamide and hexamethylphosphoramide. This process minimizes the formation of impurities such as 2,3,4-trimethoxy alfuzosin.</p>

<p>1-Oxo mirtazapine is a metabolite of mirtazapine. It is a synthetic compound and is not found in nature. This product is a research and development impurity standard for the preparation of drug product, which has been synthesized to be highly pure. The material is used for drug development, including pharmacopoeia requirements for analytical studies and metabolism studies. 1-Oxo mirtazapine has been shown to have niche applications in pharmacopoeia and as an HPLC standard.</p>