Proteínas de checkpoint imunológico
As proteínas de ponto de verificação imunológica são moléculas que geram sinais co-estimuladores ou co-inibidores durante as respostas imunológicas, relevantes na pesquisa de imunoterapia contra o câncer. Essas proteínas são alvos para terapias projetadas para modular o sistema imunológico, aumentando sua capacidade de reconhecer e destruir células cancerosas, enquanto minimizam os danos aos tecidos normais. Na CymitQuimica, oferecemos uma ampla gama de proteínas de ponto de verificação imunológica para apoiar seus esforços de pesquisa e desenvolvimento em imunoterapia.
Foram encontrados 155 produtos de "Proteínas de checkpoint imunológico"
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FGL2 Protein, Mouse, Recombinant (His & Avi, Flag), Biotinylated
Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptiveCor e Forma:Lyophilized PowderPeso molecular:31.48 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00814
5µg94,00€10µg138,00€20µg220,00€50µg434,00€100µg732,00€200µg1.324,00€500µg2.925,00€BTN1A1 Protein, Human, Recombinant (His & Avi), Biotinylated
BTN1A1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.Cor e Forma:Lyophilized PowderPeso molecular:26.9 kDa (Predicted); 30-40 kDa (Reducing conditions due to glycosylation)FGL2 Protein, Cynomolgus, Recombinant (His & Avi, Flag)
Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptiveCor e Forma:Lyophilized PowderPeso molecular:31.40 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.BTN1A1 Protein, Mouse, Recombinant (His)
BTN1A1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Cor e Forma:Lyophilized PowderPeso molecular:25.4 kDa (predicted); 32-35 kDa (reducing conditions)Ref: TM-TMPY-06537
5µg77,00€10µg109,00€20µg174,00€50µg350,00€100µg668,00€200µg1.017,00€500µg2.071,00€1mg4.207,00€BTN3A1 Protein, Human, Recombinant (hFc)
BTN3A1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:50.9 kDa (predicted)Ref: TM-TMPY-01123
5µg89,00€10µg130,00€20µg203,00€50µg409,00€100µg778,00€200µg1.132,00€500µg2.164,00€1mg4.207,00€BTN3A1 Protein, Human, Recombinant (His)
BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:98.5%Cor e Forma:Lyophilized PowderPeso molecular:25.3 kDa (Predicted); 28-35 kDa (Reducing conditions due to glycosylation)Siglec-9 Protein, Human, Recombinant (His & hFc)
Siglec-9 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:64.13 kDa (predicted); 97.5 kDa (reducing conditions)Ref: TM-TMPY-06966
5µg79,00€10µg110,00€20µg177,00€50µg359,00€100µg623,00€200µg1.080,00€500µg2.637,00€Galectin-9 Protein, Human, Recombinant (His)
Galectin-9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.Cor e Forma:Lyophilized PowderPeso molecular:49 KDa (reducing condition)Ref: TM-TMPJ-01455
5µg71,00€10µg103,00€20µg158,00€50µg279,00€100µg437,00€200µg685,00€500µg1.251,00€1mg1.783,00€CD200R Protein, Human, Recombinant (His)
CD200R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:SDS-PAGE: 98.3%; SEC-HPLC: 96.8%Cor e Forma:Lyophilized PowderPeso molecular:28.2 kDa (predicted); 50-60 kDa (reducing condition, due to glycosylation)Siglec-9 Protein, Human, Recombinant (His)
Siglec-9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Cor e Forma:Lyophilized PowderPeso molecular:37.48 kDa (predicted); 61.92 kDa (reducing conditions)Ref: TM-TMPY-06847
5µg96,00€10µg141,00€20µg224,00€50µg449,00€100µg772,00€200µg1.378,00€500µg3.412,00€CD200R Protein, Human, Recombinant (His & hFc)
CD200R Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:54.9 kDa (predicted); 90-100 kDa (reducing condition, due to glycosylation)CD200R1/CRTR2 Protein, Human, Recombinant (hFc)
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cellPureza:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC - > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLCCor e Forma:Lyophilized PowderPeso molecular:53.7 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.FGL1 Protein, Human, Recombinant (hFc)
Expression System: HEK293 Cells
Length: 23-312, Full Length of Mature Protein
Activity: ELISACor e Forma:Lyophilized PowderPeso molecular:~61.8 kDa (Reducing conditions)Ref: TM-TMPS-00034
5µg73,00€10µg104,00€20µg170,00€50µg324,00€100µg449,00€200µg795,00€500µg1.701,00€1mg3.052,00€CD200R Protein, Mouse, Recombinant (His)
CD200R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Cor e Forma:Lyophilized PowderPeso molecular:24.21 kDa (Predicted); 55-65 kDa (Due to glycosylation)Ref: TM-TMPY-01665
5µg71,00€10µg101,00€20µg166,00€50µg324,00€100µg627,00€200µg954,00€500µg2.008,00€1mg4.078,00€CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi)
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cellCor e Forma:Lyophilized PowderPeso molecular:29.7 kDa (predicted). Due to glycosylation, the protein migrates to 52-68 kDa based on Tris-Bis PAGE result.CD200R1/CRTR2 Protein, Human, Recombinant (His)
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein.Cor e Forma:Lyophilized PowderPeso molecular:50-80 KDa (reducing condition)Ref: TM-TMPJ-00233
5µg63,00€10µg90,00€20µg138,00€50µg245,00€100µg437,00€200µg782,00€500µg1.710,00€1mg2.457,00€Siglec-9 Protein,Human, Recombinant(aa 18-348, His)
Siglec-9 Protein,Human, Recombinant(aa 18-348, His) is expressed in HEK293 mammalian cells with C-6xHis tag.Cor e Forma:Lyophilized PowderPeso molecular:55-90 KDa (reducing condition)Ref: TM-TMPJ-00551
5µg104,00€10µg170,00€20µg263,00€50µg490,00€100µg732,00€200µg1.071,00€500µg1.863,00€1mg2.673,00€TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc)
Expression System: HEK293 Cells
Length: 22-200, Extracellular Domain
Activity: ELISACor e Forma:Lyophilized PowderPeso molecular:60~65 kDa (Reducing conditions)Ref: TM-TMPS-00135
5µg107,00€10µg170,00€20µg281,00€50µg560,00€100µg827,00€200µg1.224,00€500µg2.052,00€1mg3.052,00€CD200R1/CRTR2 Protein, Cynomolgus, Recombinant (His)
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cellCor e Forma:Lyophilized PowderPeso molecular:28.09 kDa (predicted). Due to glycosylation, the protein migrates to 67-77 kDa based on Tris-Bis PAGE result.PVRIG Protein, Human, Recombinant (aa 41-172, hFc)
Expression system: HEK293 Cells
Length: 41-172, Partial
Activity: ELISACor e Forma:Lyophilized PowderPeso molecular:40.5 kDa (predicted); 50.8 kDa (reducing contition, due to glycosylation)Ref: TM-TMPY-07164
5µg71,00€10µg102,00€20µg160,00€50µg309,00€100µg613,00€200µg888,00€500µg1.980,00€1mg4.050,00€B7-H4 Protein, Mouse, Recombinant (His), Biotinylated
Expression system: HEK293 Cells
Length: 29-256, Partial
Activity: Not TestedCor e Forma:Lyophilized PowderPeso molecular:26.6 kDa (predicted); 50.2 kDa (reducing contition)TIGIT Dimer Protein, Human, Recombinant (Avi & His), Biotinylated
Expression system: HEK293 Cells
Length: 22-141, Extracellular Domain
Activity: ELISACor e Forma:Lyophilized PowderPeso molecular:30.63 kDa (predicted); 39.3 kDa (reducing contition)B7-H6 Protein, Rat, Recombinant (His), Biotinylated
Expression system: HEK293 Cells
Length: 1-308, Partial
Activity: Not TestedCor e Forma:Lyophilized PowderPeso molecular:35.12 kDa (predicted)B7-H4 Protein, Rat, Recombinant (His)
Expression system: HEK293 Cells
Length: 29-256, Partial
Activity: Not TestedCor e Forma:SoildPeso molecular:26.6 kDa (predicted)TIGIT Dimer Protein, Human, Recombinant (His)
Expression system: HEK293 Cells
Length: 22-141, Extracellular Domain
Activity: SPR、BLI、Octet RED、ELISACor e Forma:Lyophilized PowderPeso molecular:28.81 kDa (predicted); 36.72 kDa (reducing contition)CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi), Biotinylated
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cellCor e Forma:Lyophilized PowderPeso molecular:29.7 kDa (predicted). Due to glycosylation, the protein migrates to 52-70 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00623
5µg94,00€10µg138,00€20µg220,00€50µg434,00€100µg732,00€200µg1.324,00€500µg2.925,00€Siglec-9 Protein, Human, Recombinant (His & Avi), Biotinylated
Siglec-9 is a sialic-acid-binding lectin expressed predominantly on myeloid cells.Cor e Forma:Lyophilized PowderPeso molecular:38.9 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00287
5µg94,00€10µg138,00€20µg220,00€50µg434,00€100µg732,00€200µg1.324,00€500µg2.925,00€BTN3A1 Protein, Human, Recombinant
BTN3A1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.16 kDa and the accession number is NP_919423.1.Cor e Forma:Lyophilized PowderPeso molecular:24.15 kDa (predicted); 26-32 kDa (reducing conditions)Ref: TM-TMPY-06663
5µg95,00€10µg147,00€20µg236,00€50µg465,00€100µg891,00€200µg1.334,00€500µg2.721,00€1mg5.507,00€TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:95.4%Cor e Forma:Lyophilized PowderPeso molecular:21.3 kDa (predicted); 42.8 kDa (reducing condition, due to glycosylation)Galectin-9 Protein, Human, Recombinant (hFc)
LGALS9 (Galectin 9) is a Protein Coding gene.Pureza:94.6%Cor e Forma:Lyophilized PowderPeso molecular:61.8 kDa (predicted); 64.8 kDa (reducing conditions)FGL1 Protein, Mouse, Recombinant (hFc)
FGL1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:60.74 kDa (predicted)Ref: TM-TMPY-05785
5µg82,00€10µg120,00€20µg187,00€50µg378,00€100µg730,00€200µg1.108,00€500µg2.277,00€1mg4.770,00€VISTA Protein, Human, Recombinant (His)
B7-H5, also known as VISTA , B7H5, Dies1, SISP1 and C10orf54, is a 55-65 kDa member of the Ig superfamily.Cor e Forma:Lyophilized PowderPeso molecular:19 kDa (predicted). Due to glycosylation, the protein migrates to 32-70 kDa based on Tris-Bis PAGE result.FGL2 Protein, Human, Recombinant (His & Avi, Flag), Biotinylated
Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptiveCor e Forma:Lyophilized PowderPeso molecular:31.2 kDa (predicted). Due to glycosylation, the protein migrates to 40-55 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00969
5µg94,00€10µg138,00€20µg220,00€50µg434,00€100µg732,00€200µg1.324,00€500µg2.925,00€IDO1 Protein, Human, Recombinant
IDO Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 45.2 kDa and the accession number is A0A348GSI3.Cor e Forma:Lyophilized PowderPeso molecular:45.2 kDa (predicted); 46 kDa (reducing conditions)B7-H4 Protein, Mouse, Recombinant (His)
B7-H4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:98.7%Cor e Forma:Lyophilized PowderPeso molecular:26.6 kDa (predicted)B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.Cor e Forma:Lyophilized PowderPeso molecular:70-95 KDa (reducing condition)CD200R Protein, Mouse, Recombinant (His & hFc)
CD200R Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:51.3 kDa (predicted); 90-100 kDa (reducing condition, due to glycosylation)FGL1 Protein, Cynomolgus, Recombinant (hFc)
FGL1 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:55.5 kDa (predicted); 62-68 kDa (reducing conditions due to glycosylation)Ref: TM-TMPY-05843
5µg82,00€10µg120,00€20µg187,00€50µg378,00€100µg730,00€200µg1.108,00€500µg2.277,00€1mg4.770,00€Siglec-9 Protein, Human, Recombinant (His & Avi)
Siglec-9 is a sialic-acid-binding lectin expressed predominantly on myeloid cells.Cor e Forma:Lyophilized PowderPeso molecular:38.9 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.FGL1 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen.Cor e Forma:Lyophilized PowderPeso molecular:54.8 kDa (predicted). Due to glycosylation, the protein migrates to 60-66 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00204
5µg94,00€10µg138,00€20µg220,00€50µg434,00€100µg732,00€200µg1.324,00€500µg2.925,00€PVRIG Protein, Mouse, Recombinant (hFc & Avi)
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.Cor e Forma:Lyophilized PowderPeso molecular:42.70 kDa (predicted). Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & His)
Hepatitis A virus cellular receptor 2（HAVCR2）is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain.Cor e Forma:Lyophilized PowderPeso molecular:80 KDa (reducing condition)Ref: TM-TMPJ-00599
5µg56,00€10µg88,00€20µg127,00€50µg234,00€100µg421,00€200µg767,00€500µg1.710,00€1mg2.457,00€FGL2 Protein, Rat, Recombinant (His & Avi, Flag), Biotinylated
Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptiveCor e Forma:Lyophilized PowderPeso molecular:31.31 kDa (predicted). Due to glycosylation, the protein migrates to 45-55 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00985
5µg94,00€10µg138,00€20µg220,00€50µg434,00€100µg732,00€200µg1.324,00€500µg2.925,00€B7-H4 Protein, Human, Recombinant (hFc)
B7-H4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:52.3 kDa (predicted); 70-80 kDa (reducing conditions)Ref: TM-TMPY-03009
5µg82,00€10µg120,00€20µg187,00€50µg378,00€100µg730,00€200µg1.108,00€500µg2.277,00€1mg4.770,00€DNAM-1/CD226 Protein, Human, Recombinant (His & Avi)
DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediatesCor e Forma:Lyophilized PowderPeso molecular:28.9 kDa (predicted). Due to glycosylation, the protein migrates to 45-70 kDa based on Tris-Bis PAGE result.B7-H6 Protein, Rat, Recombinant (hFc)
B7-H6 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:60.4 kDa (predicted)PVRIG Protein, Cynomolgus, Recombinant (hFc)
PVRIG Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.Cor e Forma:Lyophilized PowderPeso molecular:45-55 KDa (reducing condition)Ref: TM-TMPJ-00435
5µg57,00€10µg89,00€20µg128,00€50µg235,00€100µg445,00€200µg848,00€500µg2.008,00€1mg3.015,00€BTN2A2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
BTN2A2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag.Cor e Forma:Lyophilized PowderPeso molecular:55-80 KDa (reducing condition)PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.Cor e Forma:Lyophilized PowderPeso molecular:42.7 kDa (predicted). Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00471
5µg94,00€10µg138,00€20µg220,00€50µg434,00€100µg732,00€200µg1.324,00€500µg2.925,00€B7-H6 Protein, Human, Recombinant (His & Avi), Biotinylated
B7-H6 is a glycosylated member of the B7 family of immune co‑stimulatory proteins.Cor e Forma:Lyophilized PowderPeso molecular:29.6 kDa (predicted). Due to glycosylation, the protein migrates to 48-65 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00280
5µg91,00€10µg150,00€20µg239,00€50µg471,00€100µg779,00€200µg1.410,00€500µg3.018,00€
