Proteínas de checkpoint imunológico
As proteínas de ponto de verificação imunológica são moléculas que geram sinais co-estimuladores ou co-inibidores durante as respostas imunológicas, relevantes na pesquisa de imunoterapia contra o câncer. Essas proteínas são alvos para terapias projetadas para modular o sistema imunológico, aumentando sua capacidade de reconhecer e destruir células cancerosas, enquanto minimizam os danos aos tecidos normais. Na CymitQuimica, oferecemos uma ampla gama de proteínas de ponto de verificação imunológica para apoiar seus esforços de pesquisa e desenvolvimento em imunoterapia.
Foram encontrados 155 produtos de "Proteínas de checkpoint imunológico"
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PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
<p>Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.</p>Cor e Forma:Lyophilized PowderPeso molecular:42.7 kDa (predicted). Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.Galectin-9 Protein, Human, Recombinant (His)
<p>Galectin-9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:49 KDa (reducing condition)BTN1A1 Protein, Mouse, Recombinant (His)
<p>BTN1A1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:25.4 kDa (predicted); 32-35 kDa (reducing conditions)FGL2 Protein, Cynomolgus, Recombinant (His & Avi, Flag)
<p>Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive</p>Cor e Forma:Lyophilized PowderPeso molecular:31.40 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.FGL2 Protein, Mouse, Recombinant (His & Avi, Flag), Biotinylated
<p>Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive</p>Cor e Forma:Lyophilized PowderPeso molecular:31.48 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated
<p>FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:35 KDa (reducing condition)BTN3A1 Protein, Human, Recombinant (hFc)
<p>BTN3A1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:50.9 kDa (predicted)BTN3A1 Protein, Human, Recombinant (His)
<p>BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:98.5%Cor e Forma:Lyophilized PowderPeso molecular:25.6 kDa (predicted)BTN1A1 Protein, Human, Recombinant (His & Avi), Biotinylated
<p>BTN1A1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:27.20 kDa (predicted); 36.09 kDa (reducing conditions)B7-H6 Protein, Human, Recombinant (His & Avi), Biotinylated
<p>B7-H6 is a glycosylated member of the B7 family of immune co‑stimulatory proteins.</p>Cor e Forma:Lyophilized PowderPeso molecular:29.6 kDa (predicted). Due to glycosylation, the protein migrates to 48-65 kDa based on Tris-Bis PAGE result.BTN3A3 Protein, Human, Recombinant (mFc)
<p>BTN3A3 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:50 kDa (predicted); 53 kDa (reducing conditions)B7-H6 Protein, Human, Recombinant (His), Biotinylated
<p>B7-H6 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:28.1 kDa (predicted)TIGIT Protein, Mouse, Recombinant (mFc)
<p>TIGIT Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:39.93 kDa (predicted)TIGIT Protein, Human, Recombinant (mFc)
<p>TIGIT Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:39.4 kDa (predicted); 45-54 kDa (reducing condition, due to glycosylation)B7-H5/VISTA Protein, Human, Recombinant (His)
<p>VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:99.3%Cor e Forma:Lyophilized PowderPeso molecular:19.6 kDa (predicted); 38-42 kDa (reducing condition, due to glycosylation)IDO1 Protein, Mouse, Recombinant (His)
<p>IDO Protein, Mouse, Recombinant (His) is expressed in E.</p>Pureza:≥ 90 % as determined by SDS-PAGE. - ≥ 90 % as determined by SDS-PAGE.Cor e Forma:Lyophilized PowderPeso molecular:46.47 kDa (predicted)TIGIT Protein, Mouse, Recombinant (His & Avi), Biotinylated
<p>TIGIT Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:16.01 kDa (predicted); 26.6 kDa (reducing conditions)BTN3A1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
<p>Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily.</p>Cor e Forma:Lyophilized PowderPeso molecular:58-62 KDa (reducing condition)PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His)
<p>PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:99.3%Cor e Forma:Lyophilized PowderPeso molecular:15.3 kDa (predicted); 25-30 kDa (reducing condition, due to glycosylation)TIGIT Protein, Cynomolgus, Recombinant (hFc)
<p>TIGIT Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Pureza:93.1%Cor e Forma:Lyophilized PowderPeso molecular:47.2 kDa (predicted)TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)
<p>T cell immunoglobulin and mucin domain 3 is a member of the TIM family of immune regulating molecules.</p>Cor e Forma:Lyophilized PowderPeso molecular:26-30 KDa (reducing condition)TIGIT Protein, Human, Recombinant (hFc & Avi), Biotinylated
<p>TIGIT Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:41.6 kDa (predicted); 49.2 kDa (reducing condition, due to glycosylation)TIGIT Protein, Human, Recombinant (hFc)
<p>TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Pureza:95.7%Cor e Forma:Lyophilized PowderPeso molecular:39.2 kDa (predicted); 45 kDa (reducing condition, due to glycosylation)BTN1A1 Protein, Human, Recombinant (His)
<p>BTN1A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:24.98 kDa (predicted); 31-37 kDa (reducing conditions)BTNL4 Protein, Mouse, Recombinant (His)
<p>Butyrophilin-like 4, also known as BTLN4, BTN3A3 (human) and BTN3A2 (rat) is an approximately 65 kDa member of the butyrophilin family that may play a role in</p>Cor e Forma:Lyophilized PowderPeso molecular:30-40 KDa (reducing condition)FGL1 Protein, Human, Recombinant (His & Avi)
<p>FGL1 Protein, Human, Recombinant (His & Avi) is expressed in Baculovirus insect cells with His and Avi tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:37.27 kDa (predicted)PVRIG Protein, Mouse, Recombinant (hFc)
<p>PVRIG Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:48-55 KDa (reducing condition)BTN3A1 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
<p>The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate</p>Cor e Forma:Lyophilized PowderPeso molecular:26.5 kDa (predicted). Due to glycosylation, the protein migrates to 30-35 kDa based on Tris-Bis PAGE result.Galectin-9 Protein, Mouse, Recombinant (GST)
<p>Galectin-9 Protein, Mouse, Recombinant (GST) is expressed in E.</p>Pureza:Greater than 85% as determined by reducing SDS-PAGE. (QC verified) - Greater than 85% as determined by reducing SDS-PAGE. (QC verified)Cor e Forma:Lyophilized PowderPeso molecular:58 KDa (reducing condition)TIGIT Protein, Mouse, Recombinant (hFc)
<p>TIGIT Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:39.8 kDa (predicted); 52 kDa (reducing condition, due to glycosylation)TIGIT Protein, Mouse, Recombinant (His)
<p>TIGIT Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:SDS-PAGE: 94%; SEC-HPLC: 90.7%Cor e Forma:Lyophilized PowderPeso molecular:14.2 kDa (predicted); 20-25 kDa (reducing condition, due to glycosylation)TIGIT Protein, Human, Recombinant (hFc), Biotinylated
<p>TIGIT Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:39.2 kDa (predicted)B7-H6 Protein, Human, Recombinant (His)
<p>B7-H6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:28.1 kDa (predicted)PVRIG Protein, Cynomolgus, Recombinant (His)
<p>PVRIG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:20-30 KDa (reducing condition)TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His)
<p>TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His) is expressed in HEK293 mammalian cells with C-6xHis tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:38-55 KDa (reducing condition)PVRIG Protein, Human, Recombinant (hFc)
<p>PVRIG Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:36.9 kDa (predicted)FGL1 Protein, Mouse, Recombinant (His)
<p>FGL1 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:35.5 kDa (predicted)TIGIT Protein, Cynomolgus, Recombinant (His)
<p>T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins.</p>Cor e Forma:Lyophilized PowderPeso molecular:16-30 KDa (reducing condition)VISTA Protein, Human, Recombinant (hFc)
<p>B7-H5, also known as VISTA , B7H5, Dies1, SISP1 and C10orf54, is a 55-65 kDa member of the Ig superfamily.</p>Pureza:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC - > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLCCor e Forma:Lyophilized PowderPeso molecular:44.9 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.BTNL9 Protein, Human, Recombinant (His)
<p>Butyrophilin-Like Protein 9 (BTNL9) is single-pass type I membrane protein member of the BTN/MOG family that belongs to the immunoglobulin superfamily.</p>Cor e Forma:Lyophilized PowderPeso molecular:18-30 KDa (reducing condition)B7-H6 Protein, Cynomolgus, Recombinant (His)
<p>B7-H6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:27.9 kDa (predicted)TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (His)
<p>TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:20.3 kDa (predicted); 37-45 kDa (reducing condition, due to glycosylation)VSIR Protein, Cynomolgus, Recombinant (His)
<p>platelet receptor Gi24 is a single-pass type I membrane protein, and located at the cell surface.</p>Cor e Forma:Lyophilized PowderPeso molecular:30-50 KDa (reducing condition)BTN2A1 Protein, Human, Recombinant (His)
<p>Butyrophilin 2A1 (BTN2A1) is an approximately widely expressed and variably glycosylated type I transmembrane glycoprotein.</p>Cor e Forma:Lyophilized PowderPeso molecular:39-44 KDa (reducing condition)FGL1 Protein, Human, Recombinant (His)
<p>FGL1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.</p>Pureza:97.6%Cor e Forma:Lyophilized PowderPeso molecular:35.5 kDa (predicted)FGL2 Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated
<p>Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive</p>Cor e Forma:Lyophilized PowderPeso molecular:31.40 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (aa 22-200, His)
<p>TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (aa 22-200, His) is expressed in HEK293 mammalian cells with C-His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:20.7 kDa (predicted). Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.VISTA Protein, Mouse, Recombinant (His)
<p>VISTA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:19.2 kDa (predicted)B7-H6 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
<p>B7-H6 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:29.76 kDa (predicted); 49.36 kDa (reducing conditions)VISTA Protein, Cynomolgus, Recombinant (His)
<p>VISTA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:19 kDa (predicted); 40-60 kDa (reducing conditon due to glycosylation)
