Sistema complementar
O sistema complemento é uma parte crucial da resposta imunológica, consistindo em uma série de pequenas proteínas que melhoram a capacidade dos anticorpos e das células fagocíticas de eliminar patógenos de um organismo. Essas proteínas trabalham juntas para opsonizar patógenos, induzir respostas inflamatórias e lisar diretamente as membranas dos patógenos, desempenhando um papel vital na imunidade inata e na função imunológica geral. Na CymitQuimica, fornecemos proteínas de alta qualidade do sistema complemento para apoiar seus estudos imunológicos e pesquisas clínicas.
Foram encontrados 178 produtos para "Sistema complementar".
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Compstatin TFA
Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).Fórmula:C68H100F3N23O19S2Cor e Forma:SolidPeso molecular:1664.79Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.Cor e Forma:Odour SolidComplement C1s-IN-1
CAS:Complement C1s-IN-1 is a selective inhibitor of complement C1s，oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexesFórmula:C22H20F2N6OPureza:97.77%Cor e Forma:Yellow SolidPeso molecular:422.43Vemircopan
CAS:Vemircopan is a complement factor D inhibitor.Fórmula:C29H28BrN7O3Cor e Forma:SolidPeso molecular:602.493AMY-101
CAS:AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.Fórmula:C83H117N23O18S2Pureza:98%Cor e Forma:SolidPeso molecular:1789.11Zilucoplan (PEG2)
Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).Fórmula:C128H190N24O33Cor e Forma:SolidPeso molecular:2593.02C5a Anaphylatoxin (human)
CAS:C5a Anaphylatoxin (human) is a pro-inflammatory peptide that functions as a leukocyte chemoattractant, utilized in researching inflammation and immune responsesFórmula:C350H578N108O107S8Pureza:98%Cor e Forma:SolidPeso molecular:8267.51tLyP-1 peptide
CAS:tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. It can specifically bind to NRP-1 to target tumor cells.Fórmula:C31H59N15O10SCor e Forma:SolidPeso molecular:833.96CK3 peptide
CAS:CK3 peptide is an NRP-1-targeting peptide with the amino acid sequence CLKADKAKC. It specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging demonstrate that CK3 peptide significantly accumulates in xenograft tumors in nude mice. CK3 peptide is applicable for molecular imaging studies of breast cancer.Fórmula:C40H72N12O12S2Cor e Forma:SolidPeso molecular:977.203BCX 1470 hydrochloride
BCX 1470 hydrochloride is a serine protease inhibitor with anti-inflammatory activity that inhibits factor D hemolytic activity and may be used to study edema.Fórmula:C14H11ClN2O2S2Pureza:99.71%Cor e Forma:SoildPeso molecular:338.83Vensobafusp alfa
CAS:Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.Cor e Forma:LiquidOlendalizumab
CAS:Olendalizumab is an anti-C5a mAb that inhibits neutrophil activation and cytokine storms by blocking the C5a/C5aR axis for sepsis and viral infection research.Cor e Forma:LiquidPOT-4 TFA
POT-4 TFA, a Compstatin derivative, inhibits C3 activation, for macular degeneration research.Fórmula:C74H103F3N22O20S2Cor e Forma:SolidPeso molecular:1741.87BM213
CAS:BM213 is a useful organic compound for research related to life sciences and the catalog number is T35399.Fórmula:C43H70N12O10Pureza:98%Cor e Forma:SoildPeso molecular:915.09Campneoside II
CAS:Campneoside II, a compound extracted from the wood of Paulownia tomentosa var. tomentosa, demonstrates remarkable anti-complement activity [1].Fórmula:C29H36O16Cor e Forma:SolidPeso molecular:640.59PIC1 PA TFA
PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.Fórmula:C71H123N19O21S2·xC2HF3O2Cor e Forma:Solid3-Phenoxybenzaldehyde
CAS:3-Phenoxybenzaldehyde is a complement (classical pathway) inhibitor with IC50 of 1388μM.Fórmula:C13H10O2Pureza:99.01%Cor e Forma:Transparent LiquidPeso molecular:198.22ASP-1948
ASP-1948 is a human monoclonal antibody targeting NRP1/VEGF165R/CD34. It is capable of reversing the inhibitory effects of regulatory T cells and can be applied in the study of solid tumors.Cor e Forma:Odour LiquidComplement C2 Protein, Cynomolgus, Recombinant (His)
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC).Cor e Forma:Lyophilized PowderPeso molecular:82.18 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.Complement Factor MASP3 Protein, Human, Recombinant (His)
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway.Cor e Forma:Lyophilized PowderPeso molecular:95-120 KDa (reducing condition)Ref: TM-TMPJ-00980
5µg104,00€10µg170,00€20µg263,00€50µg490,00€100µg712,00€200µg1.035,00€500µg1.710,00€1mg2.457,00€
