Sistema complementar
O sistema complemento é uma parte crucial da resposta imunológica, consistindo em uma série de pequenas proteínas que melhoram a capacidade dos anticorpos e das células fagocíticas de eliminar patógenos de um organismo. Essas proteínas trabalham juntas para opsonizar patógenos, induzir respostas inflamatórias e lisar diretamente as membranas dos patógenos, desempenhando um papel vital na imunidade inata e na função imunológica geral. Na CymitQuimica, fornecemos proteínas de alta qualidade do sistema complemento para apoiar seus estudos imunológicos e pesquisas clínicas.
Foram encontrados 156 produtos de "Sistema complementar"
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C3a Receptor Agonist
CAS:<p>C3a Receptor Agonist activates C3aRs, inhibits neutrophil mobilization in ischemia, and promotes neural progenitor differentiation.</p>Fórmula:C27H35N3O2Pureza:99.76%Cor e Forma:SolidPeso molecular:433.59NDT 9513727
CAS:<p>NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders.</p>Fórmula:C36H35N3O4Pureza:99.21%Cor e Forma:SolidPeso molecular:573.68Complement C5-IN-1
CAS:<p>Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).</p>Fórmula:C24H32N2O6Pureza:98.27%Cor e Forma:SolidPeso molecular:444.52Factor D inhibitor 6
CAS:<p>Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.</p>Fórmula:C23H22ClFN6O3Cor e Forma:SolidPeso molecular:484.92W-54011
CAS:<p>W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).</p>Fórmula:C30H37ClN2O2Pureza:96.8%Cor e Forma:SolidPeso molecular:493.08Factor B-IN-2
CAS:<p>Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.</p>Fórmula:C25H32N2O4Cor e Forma:SolidPeso molecular:424.53EG01377
CAS:<p>EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.</p>Fórmula:C26H30N6O6S2Pureza:98%Cor e Forma:SolidPeso molecular:586.68C5aR-IN-1
CAS:<p>C5aR-IN-1, a potent C5aR inhibitor, may aid in researching autoimmune and inflammatory diseases.</p>Fórmula:C36H39F4N3O2Cor e Forma:SolidPeso molecular:621.71Iptacopan
CAS:<p>Iptacopan (LNP023) is an inhibitor with high affinity to factor B, with a KD value of 7.9 nM and an IC50 value of 10 nM. Cost-effective and quality-assured.</p>Fórmula:C25H30N2O4Pureza:99.07% - >99.99%Cor e Forma:SolidPeso molecular:422.52C5aR-IN-3
CAS:<p>C5aR-IN-3, a potent C5aR inhibitor, may treat autoimmune and inflammatory diseases.</p>Fórmula:C36H40FN5O3Cor e Forma:SolidPeso molecular:609.73(Rel)-Factor B-IN-5
CAS:<p>(Rel)-Factor B-IN-5 is a complement factor B inhibitor that can be used to study diseases associated with activation of the alternative complement pathway.</p>Fórmula:C27H32N2O4Pureza:>99.99%Cor e Forma:SolidPeso molecular:448.55Factor B-IN-3
CAS:<p>Factor B-IN-3 is a potent inhibitor of complement factor B. Factor B-IN-3 can be used to study inflammatory and immune-related diseases.</p>Fórmula:C24H29N3O4Cor e Forma:SolidPeso molecular:423.5Pelecopan
CAS:<p>Pelecopan (BCX9930), an oral complement factor D inhibitor, prevents hemolysis in PNH (IC50=14.3 nM).</p>Fórmula:C23H19FN2O4Cor e Forma:SolidPeso molecular:406.41Factor B-IN-4
CAS:<p>Factor B-IN-4 is a potent inhibitor (IC50: 1 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.</p>Fórmula:C27H32N2O4Cor e Forma:SolidPeso molecular:448.55TLQP-21 TFA
<p>TLQP-21 TFA is a VGF-derived peptide, C3aR1 agonist (mouse EC50: 10.3μM; human EC50: 68.8μM), that raises intracellular Ca2+ for nociception research.</p>Pureza:98%Cor e Forma:LiquidTLQP-21 TFA
<p>TLQP-21 TFA （TLQP-21 Trifluoroacetate） 是一种 VGF 衍生肽，可通过结合后折叠机制激活C3aR1 受体。</p>Pureza:98%
