Outros

<p>6-Chloro-3-indoxyl-beta-D-glucuronic acid (cyclohexylammonium salt) is a chromogenic substrate for beta-glucuronidase yielding a salmon colored precipitate upon cleavage.</p>

<p>Histochemical substrate for esterase</p>

<p>Chromogenic substrate for α-galactosidase yielding a blue precipitate. Used for species differentiation within the family Enterobacteriaceae and differentiation of Bifido bacteria species from Lactobacillus species.</p>

<p>This product is designed for the sensitive color detection andidentification of various bacteria, such as pathogenic strains of Listeria, Clostridium, Bacillus and Staphylococcus. 5-Bromo-4-chloro-3-indoxyl myo-inositol-1-phosphate (X-phos-inositol; X-IP) is a chromogenic indicator for phosphatidyl-inositol specific phospholipase C(PI-PLC, EC 4.6.1.13). The colorless product is cleaved by PI-PLC positive microorganisms in liquid media or on solid culture media and yields a blue-green color precipitate.</p>

<p>2-Chloro-4-nitrophenyl b-D-maltoheptaoside is a fluorescent compound that is used in medical research for the visualization of muscle glycogen. It is also used to study the binding of molecules to proteins, as well as to measure enzyme activity. The compound has been shown to be insensitive to changes in pH and temperature, so it can be used at different pH levels and temperatures without affecting its function. 2-Chloro-4-nitrophenyl b-D-maltoheptaoside can be detected by titration calorimetry due to its high molecular weight. The molecule's affinity for carbohydrates also allows it to be used in optimization studies of carbohydrate molecules.</p>

<p>2-Chloro-4-nitrophenyl b-D-lactoside is a chromogenic enzyme substrate used to study the activity of enzymes. It produces a color when hydrolyzed, which makes it a valuable tool in screening for enzyme activity and studying enzyme kinetics.</p>

<p>4-Nitrophenyl phosphate mono(2-amino-2-ethyl-1,3-propanediol) salt monohydrate is a chromogenic substrate that can be used to detect the presence of alkaline phosphatase. It is also used in food testing and diagnostics. 4NPPMD is a substrate for the enzyme alkaline phosphatase, which has been shown to play a role in the inflammatory response. The production of 4NPPMD by bacteria in the environment can be detected with chemiluminescence or bioluminescence. This product has been shown to react with both horseradish peroxidase and alkaline phosphatase, as well as other enzymes that are involved in metabolic pathways. This substrate also has high purity and fluorescence properties.</p>

<p>Chromogenic cephalosporin substrate for the detection of beta-lactamase activity</p>

<p>Chromogenic α-maltosidase substrate yielding a yellow solution upon cleavage.</p>

<p>2-Chloro-4-nitrophenyl-alpha-L-fucopyranoside is a compound that is commonly used as an enzyme substrate for glycogen synthase kinase (GSK). It is activated by GSK-3β and has been shown to inhibit the activity of this enzyme. This compound has also been found to have inhibitory effects on other enzymes such as carbonic anhydrase and lactate dehydrogenase. Additionally, 2-Chloro-4-nitrophenyl-alpha-L-fucopyranoside exhibits antifungal activity against various fungi, including those resistant to other antifungal agents such as fluopyram and prothioconazole. Its mechanism of action involves interfering with ergosterol biosynthesis, an essential component of fungal cell membranes. Furthermore, this compound has potential applications in the development of new drugs targeting GSK-3β and β-catenin signaling pathways, which are implicated in various diseases including cancer and neuro</p>

<p>6-Fluoro-3-indoxyl-beta-D-galactopyranoside is a fluorescent chromogenic substrate that is commonly used for the detection and quantification of beta-galactosidase activity. When this substrate is hydrolyzed by beta-galactosidase, it produces a fluorescent blue product that can be easily detected and measured using a fluorometer or spectrophotometer. This substrate is often used in microbiology and molecular biology research to study gene expression and enzyme kinetics, and is also used in medical diagnostics as a marker for specific diseases and conditions.</p>

<p>Aldol® 535 myo-inositol-1-phosphate, ammonium salt is a chromogenic substrate for the enzyme, phosphoglucomutase. This product is used for the detection of phosphoglucomutase by its ability to react with this enzyme and produce a blue or green color. Aldol® 535 myo-inositol-1-phosphate, ammonium salt is also used as a ligand in fluorescence resonance energy transfer (FRET) experiments. It has an EC number of CAS No. 2484872-80-0 and a molecular weight of 345.05 g/mol.</p>

<p>6-Chloro-3-indoxyl butyrate is a chemiluminescent substrate that is used in diagnostics and research. It has been shown to be an excellent ligand for the detection of DNA and protein. 6-Chloro-3-indoxyl butyrate can also be used as a chromogenic substrate for the detection of alkaline phosphatase, acid phosphatase, or beta-galactosidase. This product is also used in food testing, enzyme substrates, and fluorogenic substrates.</p>

<p>Chromogenic substrate for α-D-Fucosidase yielding a blue precipitate.</p>

<p>5-Bromo-4-chloro-3-indolyl b-D-xylopyranoside is an enzyme substrate. This chromogenic substrate is used for beta-D-xylosidase enzyme. In culture media, 5-Bromo-4-chloro-3-indolyl b-D-xylopyranoside is utilised for identification of bacteria such as Klebsiella and Enterobacter.</p>

<p>4-Nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt is a chromogenic substrate for N-acetylglucosamine-6-sulfatase. Upon hydrolysis, para-nitrophenol is released yielding a yellowish colour. 4-Nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt is used in different applications such as the Mucopolysaccharidosis IIID (Sanfilippo D) diagnosis</p>

<p>4-Nitrophenyl 2-acetamido-2-deoxy-a-D-glucopyranoside is a chromogenic pNP substrate specifically designed for the analysis of N-acetylglucosaminidase activity. Upon enzyme action, the substrate releases 4-nitrophenol, a yellow compound that can be detected by spectrophotometric methods, providing a reliable and sensitive means of quantifying enzyme activity. This versatile substrate is widely used in biochemical studies, disease diagnostics, and the enzyme production industry.</p>

<p>Chromogenic substrate targeting beta-D-xylosidase.  A xylanase substrate.</p>

<p>Aldol® 515 N-glutaryl-L-phenylalanine amide is a chromogenic and fluorogenic enzyme substrate used for detection of L-glutamate-phenylalanine (GluPhe)-specific peptidase activity. The colorless enzyme substrate is cleaved the GluPhe-specific peptidase, yielding development of orange-red coloration. In addition, red fluorescence is generated when Aldol® 355 fluorescence enhancer or a suitable matrix is present. Aldol® 515 N-glutaryl-L-phenylalanine amide can be used in enzyme assays and live bacterial cultures. Aldol® 515 N-glutaryl-L-phenylalanine amide is suitable for use in liquid and solid media, under aerobic as well as anaerobic conditions.</p>

<p>Chromogenic β-galactosidase substrate yielding a yellow solution upon cleavage. Can be used for the detection of coliforms due to their beta-galactosidase activity.</p>

<p>4-Nitrophenyl b-D-thiogalactopyranoside is a specialized chromogenic substrate designed for measuring the activity of thio-β-galactosidase enzymes. Upon cleavage by thio-β-galactosidase, it releases the intensely colored 4-nitrophenolate ion, providing a straightforward, sensitive, and quantitative detection method. This substrate is easily incorporated into enzyme-coupled assays, making it a reliable and convenient choice for research and diagnostic applications. With its rapid color development and high signal-to-background ratio, 4-Nitrophenyl b-D-thiogalactopyranoside is ideal for monitoring enzyme kinetics, substrate specificity evaluation, and inhibitor screening in a range of scientific and biotechnological settings.</p>

<p>Chromogenic substrate for β-D-Cellobiosidase yielding a salmon-colored precipitate.</p>

<p>5-Bromo-4-chloro-3-indolyl β-L-fucopyranoside (X-Fuc) is a chromogenic substrate specifically designed for the identification and detection of fucosidase enzyme activity. Upon cleavage by fucosidase, it generates a blue-colored 5-Bromo-4-chloro-3-hydroxy-indole precipitate, which can be easily observed under a microscope or spectrophotometer. This feature makes X-Fuc an invaluable tool across various applications, such as biochemical analysis, histochemical staining, cell biology, and enzyme kinetic assays. By providing a fast, sensitive, and reliable readout for fucosidase activity, 5-Bromo-4-chloro-3-indolyl β-L-fucopyranoside facilitates essential research in the understanding of biological processes and the development of therapeutic interventions.</p>

<p>Naphthol AS-OL is a widely used chromogenic enzyme substrate that forms a colored product upon reaction with specific enzymes. It is commonly employed in histochemical and cytochemical staining techniques to visualize enzyme activity in cells and tissues. Naphthol AS-OL is particularly useful for detecting the presence of enzymes such as alkaline phosphatase, acid phosphatase, and esterases. The resulting colored product can be easily observed under a microscope, allowing researchers to study the distribution and localization of these enzymes in various biological samples.</p>

<p>4-Nitrophenyl b-D-thioglucopyranoside is a highly sensitive chromogenic substrate designed for the colorimetric detection and quantification of thioglucosidase enzymes. Upon enzymatic cleavage, it releases a highly absorbing 4-nitrophenyl moiety, generating a yellow color that can be readily measured spectrophotometrically. This substrate is widely utilized in the study of enzyme kinetics, substrate specificity, and inhibitor screening for thioglucosidases involved in various metabolic pathways and biological processes.</p>

<p>Chromogenic substrate targeting beta-L-arabinofuranosidase</p>

<p>4-Nitrophenyl decanoate is a chromogenic substrate for lipase. Upon hydrolysis, para-nitrophenol is released yielding a yellowish colour. 4-Nitrophenyl decanoate is used in different applications such as the Pancreatic insufficiency diagnosis, lipid metabolism studies</p>

<p>Ostazin Brilliant Red H-3B Galactomannan is a chemiluminescent substrate used for the detection of β-1,4-galactomannans. It reacts with the glucose residues on the mannan backbone to produce a red fluorescent product. This product can be detected by spectrophotometry at an excitation wavelength of 395 nm and emission wavelength of 510 nm. The Ostazin Brilliant Red H-3B Galactomannan substrate is useful in detecting Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Group A streptococci, Group B streptococci, Group D streptococci, Group G streptococci, and Group C streptococci.</p>

<p>A substrate for alkaline phosphatase yielding a blue insoluble product upon cleavage. Colour can be further enhanced when used together with Nitroblue tetrazolium. The substrate system is versatile and has functions in a variety of applications, including Northern, Southern, and Western blotting, in situ hybridization, ELISAs, microarray and immunohistochemistry. The micronized structure enhances solubility.</p>

<p>Used as substrate for chemiluminescent assay of alkaline phosphatase (ALP) to produce a blue colour precipitate when cleaved.</p>

<p>Chromogenic substrate for α-L-Fucosidase. 2-naphthol is released upon hydrolyzation. By simultaneous coupling with a suitable staining reagent, such as hexazonium p-rosaniline, the corresponding azo-dye is formed. Naphthols can also be detected by fluorescence analysis.</p>

<p>6-Chloro-3-indoxyl palmitate is a high quality, pure chemical reagent that can be used as a substrate for enzyme activity. It is a chromogenic substrate that is used in the detection of esterase activity. 6-Chloro-3-indoxyl palmitate is also used as a fluorogenic substrate in the presence of horseradish peroxidase and hydrogen peroxide to produce chemiluminescence. 6-Chloro-3-indoxyl palmitate has been shown to be an effective bioluminescent substrate for luciferase enzymes, such as firefly luciferase and Renilla luciferase.</p>

<p>5-Bromo-4-chloro-3-indolyl b-D-lactopyranoside is a chromogenic substrate used to detect the specific enzymatic activity of beta-galactosidase. After cleavage, 5-bromo-4-chloro-indoxyl is released, resulting in a blue to blue-green color change in bacterial colonies or media. 5-Bromo-4-chloro-3-indolyl b-D-lactopyranoside is used in lactose intolerance screening.</p>

<p>Aldol 458 acetate is a fluoroquinolone antibiotic. It is an enzyme substrate that can be used in the detection of β-galactosidase, alkaline phosphatase, and other enzymes. Aldol 458 acetate can be used for the detection of β-galactosidase by chemiluminescence or bioluminescence. It has been shown to have high purity and high quality as well as being a ligand that can be conjugated with a fluorescent dye to provide a fluorescent substrate. Aldol 458 acetate can also be used in culture media for the growth of bacteria. It has been shown to have strong inhibitory effects on Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, and Staphylococcus aureus.</p>

<p>Chromogenic substrate for β-glucuronidase (GUS) yieldinga blue precipitate. It is used for detection of GUS+ bacterial colonies and has been reported as chromogenic substrate in a number of chromogenic E. coli / coliform culture media. About 95% of common E. coli possess β-D-glucuronidase activity. Such chromogenic culture media are used for detection and enumeration of E. coli in food samples such as meat, dairy products, shellfish and have clinical applications in the assessment of urinary infections. It has gained international acceptance as highly accurate test for the presence of E. coli in drinking water samples. It is also used for the detection of the expression of GUS (E. coli β-glucuronidase) gene fusion marker constructs in plants.</p>

<p>5-Bromo-6-chloro-3-indolyl a-D-galactopyranoside is a chromogenic substrate that yields a magenta-colored product after cleavage. The chromophore 5-bromo-6-chloro-indoxyl is released, generating the observable color. It is used in glycolipid metabolism studies.</p>

<p>1-Naphthyl β-D-mannopyranoside is a chromogenic (also fluorogenic) substrate. After cleavage, 1-naphthol is released and is used to quantify beta-mannosidase activity.</p>

<p>8-Hydroxyquinoline-beta-D-glucuronic acid, sodium salt is a fluorogenic substrate that can be used for enzymatic detection of peroxidase. The substrate is available in a variety of forms, including powder and liquid. This product has been tested for environmental and bioluminescence activity, as well as food safety. It has also been shown to be a useful ligand in immunoassays.</p>

<p>Aldol 584 is a chromogenic substrate that is used in enzymatic assays to detect the presence of an enzyme. It is a triethylammonium salt with beta-D-glucuronic acid. Aldol 584 is used in diagnostic procedures and can be used as a substrate for fluorogenic substrates and chemiluminescent substrates. This product has been shown to be effective in detecting the presence of bile in feces, erythrocyte hemolysis, and the presence of proteinases in human urine. It can also be used as a food testing agent or to measure bacterial activity in culture media.</p>

<p>3-Nitrophenyl beta-D-glucopyranoside is a chromogenic enzyme substrate commonly used to assay for beta-glucosidase activity. Upon hydrolysis by the enzyme, it produces a yellow product that can be easily detected by spectrophotometry. This substrate is often used in the field of carbohydrate chemistry and biochemistry to study enzyme kinetics and inhibition in both in vitro and in vivo systems.</p>

<p>5-Bromo-4-chloro-3-indoxyl phosphate, dilithium salt hydrate is a chromogenic substrate used to detect the specific enzymatic activity of alkaline phosphatase. After cleavage, 5-bromo-4-chloro-indoxyl is released, resulting in a blue to blue-green color change in bacterial colonies or media. 5-Bromo-4-chloro-3-indoxyl phosphate, dilithium salt hydrate is used in ELISA and molecular biology assays such as lacZ reporter systems.</p>

<p>6-Chloro-1H-indol-3-yl hexadecanoate is a chromogenic substrate for an enzyme that oxidizes it to produce a blue color. It can be used in the diagnosis of bacterial infections, such as tuberculosis and leprosy. 6CHIH is a ligand for various enzymes, including lactate dehydrogenase, which catalyzes the conversion of pyruvate to lactic acid. This compound reacts with oxygen to produce light in the presence of a catalyst. 6CHIH is also used as a fluorescent tag for protein labeling and detection.<br>6CHIH has been shown to be effective in detecting bacteria in food products and water samples using bioluminescence techniques. The high purity and quality of this compound make it suitable for use in diagnostics, culture media, and environmental testing.</p>

<p>Chromogenic substrate for N-Acetyl-β-D-glucosaminidase yielding a magenta precipitate.</p>

<p>4-Nitrophenyl 2-acetamido-3-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-alpha-D-galactopyranoside is a chromogenic substrate for alpha-galactosidase. Upon hydrolysis, para-nitrophenol is released yielding a yellowish colour. 4-Nitrophenyl 2-acetamido-3-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-alpha-D-galactopyranoside is used in different applications such as the Fabry disease diagnosis, glycolipid metabolism studies</p>

<p>2-Naphthyl butyrate is used as a chromogenic substrate in hematological studies via measuring esterase activity. This type of assays are important as it can help in distinguishing acute leukemias with monocytic or granulocytic differentiation. After hydrolysis of 2-naphthyl butyrate by the esterase (for example acylase), b-napthol is released that can be quantified spectrophotometrically (Exc 320 nm; Em 410 nm).</p>

<p>5-Amino-3-indoxyl-beta-D-galactopyranoside (AIG) is a chromogenic substrate that is used for the detection of beta-galactosidase activity. AIG is also used in food testing, diagnostics, and environmental testing. The detection of beta-galactosidase activity can be done by either using the fluorogenic substrate 4-methylumbelliferyl galactopyranoside or the bioluminescence system of firefly luciferase and luciferin. This product has a CAS number of 110114-03-0 and a molecular weight of 417.5 g/mol.</p>

<p>4-Nitrophenyl 2,3,4,6-tetra-O-acetyl-a-D-thiomannopyranoside is a pNP substrate that serves as a chromogenic substrate for enzyme assays. It has been tested for the detection of a-D-mannosidase activity in a variety of biological samples, including cell lysates, body fluids, and tissue homogenates.</p>

<p>Chromogenic substrate to visualize the activity of alpha-D-mannopyranoside; red color produced</p>

<p>Aldol® 518 beta-D-glucuronic acid is a chromogenic and fluorogenic enzyme substrate used for detection of beta-glucuronidase activity, yielding red colour and red fluorescence. Living cells of Escherichia coli can be reliably detected with Aldol® 518 beta-D-glucuronic acid-containing media. Aldol® 518 beta-D-glucuronic acid can be also used in GUS reporter assays, e.g. in plant biotechnology. Aldol® 518 beta-D-glucuronic acid is suitable for use in liquid and solid media, under aerobic as well as anaerobic conditions.</p>

<p>Aldol® 458 phosphate is a chromogenic and fluorogenic enzyme substrate used for detection of phosphatase activity. The colorless enzyme substrate is cleaved by phosphatases secreted by bacteria grown in liquid media, yielding yellow color and green fluorescence. Aldol® 458 phosphate can also be used in assays involving phosphatase-coupled antibodies in immunoassay applications (ELISA). Aldol® 458 phosphate can be used under aerobic and anaerobic conditions.</p>