Cetonas e Derivados
As cetonas são compostos orgânicos que contêm um grupo carbonilo (C=O) ligado a dois átomos de carbono, formando uma estrutura onde o grupo carbonilo é flanqueado por grupos alquila ou arila. Na farmacologia, as cetonas são utilizadas na formulação de APIs devido à sua capacidade de melhorar a solubilidade e a estabilidade dos princípios ativos. Algumas cetonas possuem propriedades anti-inflamatórias, analgésicas e antimicrobianas. Os derivados de cetonas incluem compostos nos quais o grupo carbonilo é modificado, como os enóis, que têm aplicações na síntese de fármacos e como intermediários químicos na produção de outros compostos bioativos. Os derivados de cetonas são utilizados no desenvolvimento de novos medicamentos, incluindo aqueles para o tratamento de doenças neurodegenerativas, distúrbios metabólicos e certos tipos de câncer, devido aos seus efeitos específicos sobre enzimas e processos celulares.
Foram encontrados 2393 produtos de "Cetonas e Derivados"
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Desmethyl Ketoprofen
CAS:Produto Controlado<p>Impurity Ketoprofen EP Impurity B<br>Applications Desmethyl Ketoprofen (Ketoprofen EP Impurity B) shows antiinflammatory and analgesic activities. It can be used as neoplasm inhibitors and for treatment of angiogenesis-related disorders.<br>References Allais, A., et al.: Eur. J. Med. Chem., 9, 381 (1974).<br></p>Fórmula:C15H12O3Cor e Forma:WhitePeso molecular:240.25a-Terpinene (~90%)
CAS:Produto ControladoFórmula:C10H16Pureza:~90%Cor e Forma:ColourlessPeso molecular:136.23trans-Capsaicin
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Capsaicin analogue (C175680). It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Artursson., et al.: J. Pharma. Sci., 73, 1507 (1984), Fu., et al.: Pharma. Res., 2000, 17, 100 (2000),<br></p>Fórmula:C18H27NO3Cor e Forma:White To Off-WhitePeso molecular:305.413,4,5-Trimethoxybenzoic Acid
CAS:<p>Applications A metabolite of Trimebutine (T795605(P)), which is an opioid receptor agonist and an antispasmodic.<br>References Dieks, H., et al.: J. Labelled Comp. Radiopharm., 28, 1093 (1990), Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Fórmula:C10H12O5Cor e Forma:White To BeigePeso molecular:212.20(S)-Naproxen Methyl Ester
CAS:<p>Impurity Naproxen EP Impurity E<br>Applications Naproxen (N377520) methyl derivative. Naproxen impurity. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) indicated for the treatment of pain, inflammatory conditions such as rheumatoid arthritis, and fever. The drug belongs to the 2-aryl propionic acid family of COX-1 and COX-2 inhibitors.<br>References Haddock, R., et al.: Xenobiotica, 14, 327 (1984), Jeremy, J., et al.: Drugs, 40, 53 (1990), Wadhwa, L., et al.: Int. J. Pharm., 118, 31 (1995),<br></p>Fórmula:C15H16O3Cor e Forma:NeatPeso molecular:244.29rac Ketorolac-d4 (>90%)
CAS:Produto Controlado<p>Applications Labelled Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rooks, W.H., et al.: Agents Actions, 12, 684 (1982), Guzman, A., et al.: J. Med. Chem., 29, 589 (1986), McQuary, H.J., et al.: Clin. Pharmacol. Ther., 39, 89 (1986),<br></p>Fórmula:C15H9D4NO3Pureza:>90%Cor e Forma:NeatPeso molecular:259.29rac Ketoprofen
CAS:Produto Controlado<p>Applications Anti-inflammatory; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),<br></p>Fórmula:C16H14O3Cor e Forma:NeatPeso molecular:254.283,5-Dimethylphenoxymethyloxirane
CAS:Produto Controlado<p>Applications 3,5-Dimethylphenoxymethyloxirane is a reactant used in the preparation of thiiranes.<br>References Thirupathaiah, A., et. al.: Oriental J. Chem., 25, 771 (2009)<br></p>Fórmula:C11H14O2Cor e Forma:NeatPeso molecular:178.233-Methylnonane-2,4-dione (>80%)
CAS:Produto Controlado<p>Applications 3-Methylnonane-2,4-dione is a compound that possesses a butter-like and beany off flavour that is a result of flavour reversion of soya-bean oil. 3-Methylnonane-2,4-dione is also present in Japanese green tea and pressure-cooked hen meat.<br>References Farkaš, P., et al.: Food Chem., 60, 617 (1997); Guth, H. & Grosch, W.: Flav. Chem., No vol. given, 377 (1999); Kumazawa, K. & Masuda, H.: J. Agr. Food Chem., 47, 5169 (1999)<br></p>Fórmula:C10H18O2Pureza:>80%Cor e Forma:NeatPeso molecular:170.25p-Butyl Ibuprofen Sodium Salt
CAS:<p>Impurity Ibuprofen EP Impurity B<br>Applications p-Butyl Ibuprofen Sodium Salt (Ibuprofen EP Impurity B) is an Ibuprofen (I140000) impurity.<br>References Kalafut, P. et al.: J. Pharm. Biomed. Anal., 49, 1150 (2009); Kucera, R. et al.: J. Pharm. Biomed. Anal., 38, 609 (2005);<br></p>Fórmula:C13H17O2·NaCor e Forma:White To Off-WhitePeso molecular:228.263-Carboxy-α-methylbenzeneacetic Acid(Ketoprofen Impurity)
CAS:<p>Impurity Ketoprofen EP Impurity C; Ketoprofen USP Compound C: (2-(3-Carboxyphenyl)propionic Acid)<br>Applications 3-Carboxy-α-methylbenzeneacetic Acid (Ketoprofen EP Impurity C) is a impurity of Ketoprofen (K200800). Ketoprofen USP Compound C: (2-(3-Carboxyphenyl)propionic Acid)<br>References Dvorak, J., et al.: J. Pharm. Biomed. Anal., 36, 625 (2004), Allegretti, M., et al.: J. Med. Chem., 48, 4312 (2005),<br></p>Fórmula:C10H10O4Cor e Forma:Off-WhitePeso molecular:194.18(R)-Apomorphine-d5 Hydrochloride (Major)
CAS:Produto ControladoFórmula:C17H12D5NO2•HClCor e Forma:NeatPeso molecular:272.3636464’-Hydroxyacetophenone Oxime
CAS:Produto Controlado<p>Impurity Paracetamol EP Impurity G<br>Applications 4’-Hydroxyacetophenone Oxime is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Sengupta, S., et al.: Metal. Based Drugs, 8, 293 (2002) (2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)<br></p>Fórmula:C8H9NO2Cor e Forma:NeatPeso molecular:151.164-Acetamidophenyl β-D-Glucuronide Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-Acetamidophenyl β-D-Glucuronide is a major urinary metabolite of Acetaminophen (A161220) (Paracetamol) in human (1). Acetaminophen is an analgesic and antipyretic agent and used as a pain reliever to treat headache, muscle aches, and arthritis (2,3).<br>References (1) Johnston, D., et al.: J. Chem. Res., Synop., 12, 406 (1988)(2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)<br></p>Fórmula:C14H16NO8·NaCor e Forma:White To Light RedPeso molecular:349.27Nitrobenzene
CAS:Produto Controlado<p>Applications Nitrobenzene is a compound that exhibits chromosomal genotoxicity against hamster lung cells, and has the potential to cause cancer in humans (1,2). Nitrobenzene is also used as a starting material to synthesize 4-Aminophenol (A618920) through catalytic hydrogenation (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Bonacker, D. et al.: Arch. Toxicol. 2004 Jan;78(1):49-57.2. Hsu, C. et al.: J. Environ. Sci. Health. C. Environ. Carcinog. Ecotoxicol. Rev. 2007 Apr-Jun;25(2):155-843. Rode, C. et al.: Org. Proc. Res. Dev. 1999 Nov;3(6), pp 465–470<br></p>Fórmula:C6H5NO2Cor e Forma:Light YellowPeso molecular:123.11Terpinolene (~90%)
CAS:Produto Controlado<p>Applications Terpinolene is a chemical constituent of essential oils found in many plant species and exhibits analgesic and anti-inflammatory properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Macedo, E. M., et al.: Braz J Med Biol Res. 49, S0100 (2016); Garcia, G., et al.: Molecules. 22, E921 (2017)<br></p>Fórmula:C10H16Pureza:>85%Cor e Forma:ColourlessPeso molecular:136.235'-Acetyl-2'-chloro-3-methyl-[1,1'-biphenyl]-4-carbaldehyde
CAS:Pureza:98%Peso molecular:272.7300109863281rac-Trimethyl Ketoprofen (Mixture of (2’,3’4’) and (3’,4’,5’) Isomers)
Produto ControladoFórmula:C19H20O3Cor e Forma:NeatPeso molecular:296.363-Hydroxyacetaminophen-D3
CAS:Produto Controlado<p>Applications 3-Hydroxyacetaminophen-d3 is deuterium labeled 3-Hydroxyacetaminophen (H714750). 3-Hydroxyacetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Chen, C., et al.: J. Biol. Chem., 283, 4543 (2008)(2) Reith, D., et al.: Clin. Exper. Pharmacol. Physiol., 36, 35 (2009) (3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)<br></p>Fórmula:C82H3H6NO3Cor e Forma:NeatPeso molecular:170.18(-)-O-Desmethyl Tramadol
CAS:Produto Controlado<p>Applications A optically active metabolite of Tramadol.<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Fórmula:C15H23NO2Cor e Forma:White To Off-WhitePeso molecular:249.35(S)-Naproxen Ethyl Ester
CAS:<p>Impurity Naproxen EP Impurity F<br>Applications Naproxen (N377520) ethyl derivative. Naproxen impurity.<br>References Haddock, R., et al.: Xenobiotica, 14, 327 (1984), Jeremy, J., et al.: Drugs, 40, 53 (1990), Wadhwa, L., et al.: Int. J. Pharm., 118, 31 (1995),<br></p>Fórmula:C16H18O3Cor e Forma:NeatPeso molecular:258.31Acetaminophen Glutathione Disodium Salt
CAS:<p>Applications Acetaminophen Glutathione Disodium Salt is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3,4).<br>References (1) Chen, C., et al.: Xenobiotica, 30, 1019 (2000) (2) Ikeda, H., et al.: Biochem. J., 364, 563 (2002) (3) Aleksunes, L., et al.: Toxicol. Sci., 83, 44 (2005) (4) Elsby, R., et al.: J. Biol. Chem., 278, 22243 (2003)<br></p>Fórmula:C18H22N4Na2O8SCor e Forma:White To BrownPeso molecular:500.433-Methoxy Acetaminophen
CAS:<p>Applications 3-Methoxy Acetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C9H11NO3Cor e Forma:NeatPeso molecular:181.19Capsaicin-d3 (E/Z-Mixture)
CAS:Produto Controlado<p>Applications A representative lot is a 5:1 E:Z mixture.Labelled Capsaicin (C175680). Has been isolated from paprika and cayenne. It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.Note this is a powerful irritant. One part in 100 000 can be tasted.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Molnar, et al.: Arzneim.-Forsch., 15, 718 (1965), Monsereenusorn,Y., et al.: Crit. Rev. Toxicol., 10, 321 (1982),<br></p>Fórmula:C18D3H24NO3Cor e Forma:NeatPeso molecular:308.432′,4′,5′-Trifluoropropiophenone
CAS:Fórmula:C9H7F3OCor e Forma:Low Melting SolidPeso molecular:188.149N-Benzyl Hydroxymedetomidine
CAS:Produto Controlado<p>Applications N-Benzyl Hydroxymedetomidine is an impurity of Medetomidine (M203250, HCl); an α2-adrenergic agonist, sedative, and analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987); Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987); Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988); Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996)<br></p>Fórmula:C20H22N2OCor e Forma:NeatPeso molecular:306.4rac N-Bisdesmethyl Tramadol, Hydrochloride
CAS:<p>Applications A metabolite of Tramadol.<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Fórmula:C14H22ClNO2Cor e Forma:NeatPeso molecular:271.78rac-Ketoprofen Tris Base Amide
CAS:Produto Controlado<p>Applications rac-Ketoprofen Tris Base Amide is derived from rac Ketoprofen (K200800), which is an anti-inflammatory and analgesic.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990);<br></p>Fórmula:C20H23NO5Cor e Forma:NeatPeso molecular:357.15762285(±)-Ketoprofen-d4 (propionic-d4 acid)
CAS:Produto Controlado<p>Applications (±)-Ketoprofen-d4 (propionic-d4 acid) (CAS# 1219805-29-4) is a useful isotopically labeled research compound.<br></p>Fórmula:C162H4H10O3Cor e Forma:NeatPeso molecular:258.31N-[4-[(4-Hydroxyphenyl)amino]phenyl]acetamide
CAS:<p>Stability Hygroscopic<br>Applications N-[4-[(4-Hydroxyphenyl)amino]phenyl]acetamide is used in the synthesis of lithographic plates.<br></p>Fórmula:C14H14N2O2Cor e Forma:NeatPeso molecular:242.27rac Ketoprofen-13C,d3
CAS:Produto Controlado<p>Applications Anti-inflammatory; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),<br></p>Fórmula:CC152H3H11O3Cor e Forma:NeatPeso molecular:258.293-(1-Cyanoethyl)benzoic Acid
CAS:Produto Controlado<p>Applications 3-(1-Cyanoethyl)benzoic Acid is an intermediate for the synthetic preparation of various pharmaceutical compounds. 3-(1-Cyanoethyl)benzoic Acid was used in studies examining the enantioselectivity of nitrile hydratases.<br>References Rzeznicka, K., et al.: App. Microbiol. Biotechnol., 85, 1417 (2010); Van Pelt. S., et al.: Org. Biomole. Chem., 9, 3011 (2011);<br></p>Fórmula:C10H9NO2Cor e Forma:BeigePeso molecular:175.18Acetaminophen Dimer-d6
CAS:Produto Controlado<p>Applications Acetaminophen Dimer-d6 is deuterium labeled Acetaminophen Dimer (A161235). Acetaminophen Dimer is an oxidatively couple dimer of Acetaminaphen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1). Acetaminophen Dimer along with other p-acetamidophenol analogs were used to determine peroxidase activities (2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Potter, D.W. et al.: Mol. Pharmacol., 29, 155 (1986)(3) Shiga, M. et al.: Anal. Sci., 11, 195 (1995)<br></p>Fórmula:C16H10D6N2O4Cor e Forma:NeatPeso molecular:306.35N-Nitroso Rac N-Desmethyl Tramadol
Fórmula:C15H22N2O3Cor e Forma:Colourless To Light YellowPeso molecular:278.347Ref: 10-F506307
1gA consultar2gA consultar5gA consultar10gA consultar25gA consultar100mgA consultar250mgA consultar500mgA consultar4-Isobutylbenzoic Acid
CAS:<p>Applications 4-Isobutylbenzoic Acid is used in the studies for the identification of the degradation products and potential impurities in Ibuprofen. 4-Isobutylbenzoic Acid is also applied in the determination of related substances in dexibuprofen using HPLC.<br>References Dondoni, A., et al.: Farmaco, Edizione Pratica, 41, 237 (1986); Xie, L., et al.: Zhongguo Yaoshi, 19, 1088 (2016)<br></p>Fórmula:C11H14O2Cor e Forma:NeatPeso molecular:178.232-(p-Tolyl)propionic Acid
CAS:Produto Controlado<p>Impurity Ibuprofen EP Impurity D<br>Applications 2-(p-Tolyl)propionic acid (Ibuprofen EP Impurity D) is an impurity of Ibuprofen (I140000). Ibuprofen impurity D.<br>References Jia, C., et al.: Science, 287, 1992 (2000), Yu, J., et al.: Org. Biomol. Chem., 4, 4041 (2006),<br></p>Fórmula:C10H12O2Cor e Forma:White To Off-WhitePeso molecular:164.20Ketoprofen Acyl-β-D-glucuronide (Mixture of Diastereomers)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A metabolite of Ketoprofen (K200800(P)), which is an anti-inflammatory; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Skordi, E., et al.: Xenobiotica, 34, 1075 (2004); Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981); Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990)<br></p>Fórmula:C22H22O9Cor e Forma:NeatPeso molecular:430.40L-Lysine Clonixinate
CAS:<p>Applications L-Lysine Clonixinate is a non-morphinic andalgesic.<br>References Krymchantowski, A., et al.: Curr. Ther. Res., 64, 505 (2003), Di Girolamo, G., et al.: Brit. J. Pharmacol., 141, 1234 (2004),<br></p>Fórmula:C13H11ClN2O2·C6H14N2O2Cor e Forma:Off WhitePeso molecular:408.883′,5′-Dimethyl-4′-methoxyacetophenone
CAS:Fórmula:C11H14O2Pureza:97.0%Cor e Forma:SolidPeso molecular:178.231Trinexapac-ethyl
CAS:<p>Applications Trinexapac-ethyl<br></p>Fórmula:C13H16O5Cor e Forma:WhitePeso molecular:252.262-[4-(2-Methylpropenyl)phenyl]propionic Acid
CAS:<p>Applications 2-[4-(2-Methylpropenyl)phenyl]propionic Acid is a byproduct of Ibuprofen (I140000(P)), which is an anti-inflammatory drug.<br>References Sharma, K., et al.: Int. J. Environ. Sci. Tech., 16, 8315 (2019)<br></p>Fórmula:C13H16O2Cor e Forma:Light YellowPeso molecular:204.26N-Demethyl Trimebutine-d5 Hydrochloride
CAS:Produto Controlado<p>Applications The main bioactive labelled metabolite of Trimebutine.<br>References Miura, Y., et al.: Drug Metab. Dispos., 17, 455 (1989), Xue, L., et al.: Eur. J. Pharmacol., 294, 75 (1995), Roman, F., et al.: J. Pharmacol. Exp. Ther., 289, 1391 (1999), Kayser, V., et al.: Life Sci., 66, 433 (2000),<br></p>Fórmula:C21H22D5NO5·HClCor e Forma:NeatPeso molecular:414.931-(2,4-Bis(benzyloxy)-6-hydroxyphenyl)ethanone
CAS:Pureza:95.0%Cor e Forma:Liquid, No data available.Peso molecular:348.39801025390625Ref: 10-F229499
1gA consultar5gA consultar10gA consultar25gA consultar100gA consultar250mgA consultarrac 1-Methoxy Ketorolac
CAS:Produto Controlado<p>Applications An impurity of the analgesic Ketorolac (K235650).<br></p>Fórmula:C16H15NO4Cor e Forma:NeatPeso molecular:285.29
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