Cetonas e Derivados
As cetonas são compostos orgânicos que contêm um grupo carbonilo (C=O) ligado a dois átomos de carbono, formando uma estrutura onde o grupo carbonilo é flanqueado por grupos alquila ou arila. Na farmacologia, as cetonas são utilizadas na formulação de APIs devido à sua capacidade de melhorar a solubilidade e a estabilidade dos princípios ativos. Algumas cetonas possuem propriedades anti-inflamatórias, analgésicas e antimicrobianas. Os derivados de cetonas incluem compostos nos quais o grupo carbonilo é modificado, como os enóis, que têm aplicações na síntese de fármacos e como intermediários químicos na produção de outros compostos bioativos. Os derivados de cetonas são utilizados no desenvolvimento de novos medicamentos, incluindo aqueles para o tratamento de doenças neurodegenerativas, distúrbios metabólicos e certos tipos de câncer, devido aos seus efeitos específicos sobre enzimas e processos celulares.
Foram encontrados 2393 produtos de "Cetonas e Derivados"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
(-)-N,N-Bisdesmethyl Tramadol
CAS:Produto Controlado<p>Applications A optically active metabolite of Tramadol.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Fórmula:C14H21NO2Cor e Forma:NeatPeso molecular:235.32Medetomidine
CAS:<p>Medetomidine (MPV785 free base) is a selective α2-adrenoceptor agonist, with sedative and analgesic and vasoconstrictive hypoxic , in small animal anesthesia.</p>Fórmula:C13H16N2Pureza:99.88%Cor e Forma:SolidPeso molecular:200.28Acetaminophen-d3
CAS:Produto Controlado<p>Applications Acetaminophen-d3 is deuterium labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C82H3H6NO2Cor e Forma:WhitePeso molecular:154.18Acetaminophen-13C2, 15N1
CAS:Produto Controlado<p>Applications Acetaminophen-13C2, 15N1 is doubly labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C613C2H915NO2Cor e Forma:WhitePeso molecular:154.14(S)-(+)-Ketoprofen-13C,d3
CAS:Produto Controlado<p>Applications Labelled (S)-(+)-Ketoprofen (K200805). Anti-inflammatory; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),<br></p>Fórmula:CC15D3H11O3Cor e Forma:NeatPeso molecular:258.29Nabumetone
CAS:Produto Controlado<p>Applications Nabumetone is an anti-inflammatory and antibacterial agent (1). A non-steroidal anti-inflammatory prodrug used for treatment of inflammatory and degenerative rheumatic diseases.<br>References (1) Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006)<br></p>Fórmula:C15H16O2Cor e Forma:NeatPeso molecular:228.291-Keto Ketorolac
CAS:Produto Controlado<p>Impurity Ketorolac EP Impurity B; Ketorolac USP Related Compound C<br>Applications 1-Keto Ketorolac (Ketorolac EP Impurity B; Ketorolac USP Related Compound C) is a Ketorolac impurity. Ketorolac or ketorolac tromethamine is a non-steroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives, often used as an analgesic.<br>References Mroszczak, E., et al.: Drug Metab. Dispos., 15, 618 (1987), Gillis, J., et al.: Drugs, 53, 139 (1997),<br></p>Fórmula:C14H11NO2Cor e Forma:Light YellowPeso molecular:225.24rac-2’,4’,5’-Trimethyl Ketoprofen
CAS:Produto Controlado<p>Applications rac-2,4’,5’-Trimethyl Ketoprofen is an impurity of Ketoprofen (K200800), an anti-inflammatory and analgesic agent.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981); Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990)<br></p>Fórmula:C19H20O3Cor e Forma:NeatPeso molecular:296.36N-(1-Phenylethyl) Ibuprofen Amide(Mixture of 4 Diastereomers)
CAS:Produto Controlado<p>Applications Ibuprofen (I140000) impurity, an anti-inflammatory compound.<br>References Rubin, A., et al.: J. Pharm. Sci., 74, 82 (1985), Tracy, T., et al.: Drug Metab. Dispos., 20, 322 (1992),<br></p>Fórmula:C21H27NOCor e Forma:WhitePeso molecular:309.45N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide
CAS:Produto Controlado<p>Impurity Acetaminophen Impurity B<br>Applications N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide is an impurity of Acetaminophen (A161220), which is an analgesic and antipyretic (1,2,3,4). N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide may be a useful reagent to investigate mechanisms related to liver and kidney damage from acetaminophen. Acetaminophen Impurity B.<br>References (1) Potter, D. W. and Hinson, J. A.: Drug Metab Rev. 20, 341 (1989) (2) Potter, D. W. and Hinson, J. A.: J. Biol. Chem. 260, 12174 (1985) (3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)(4) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C16H16N2O4Cor e Forma:NeatPeso molecular:300.31trans-Capsaicin-d3
CAS:Produto Controlado<p>Applications Labelled Capsaicin analogue (C175680). It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Artursson., et al.: J. Pharma. Sci., 73, 1507 (1984), Fu., et al.: Pharma. Res., 17, 100 (2000),<br></p>Fórmula:C18H24D3NO3Cor e Forma:NeatPeso molecular:308.433-Ethylbenzophenone
CAS:Produto Controlado<p>Applications 3-Ethylbenzophenone is the photodegradation product of Ibuprofen (I40000) and Ketoprofen (K200800)in aqueous solutions.<br>References Alapi, T., et al.: J. Photochem. Photobiol., 188, 409 (2007), Musa, K., et al.: Med. Chem., 50, 1735 (2007),<br></p>Fórmula:C15H14OCor e Forma:NeatPeso molecular:210.272′-Fluoro-5′-(trifluoromethyl)propiophenone
CAS:Fórmula:C10H8F4OPureza:≥97%Cor e Forma:LiquidPeso molecular:220.167Ref: 10-F506051
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultar(R)-(-)-Ketoprofen
CAS:Produto Controlado<p>Applications Anti-inflammatory; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),<br></p>Fórmula:C16H14O3Cor e Forma:NeatPeso molecular:254.283-Acetylbenzophenone
CAS:<p>Impurity Ketoprofen EP Impurity A; Ketoprofen USP Related Compound D<br>Applications 3-Acetylbenzophenone (Ketoprofen EP Impurity A) is a Ketoprofen intermediate. Ketoprofen USP Related Compound D.<br>References Dvorak, J., et al.: J. Pharm. Biomed. Anal., 36, 625 (2004), Zhang, X., et al.: Bioorg. Med. Chem. Lett., 14, 1205 (2004),<br></p>Fórmula:C15H12O2Cor e Forma:Off-White To Light YellowPeso molecular:224.253-Hydroxyacetaminophen
CAS:Produto Controlado<p>Applications 3-Hydroxyacetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Chen, C., et al.: J. Biol. Chem., 283, 4543 (2008)(2) Reith, D., et al.: Clin. Exper. Pharmacol. Physiol., 36, 35 (2009) (3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)<br></p>Fórmula:C8H9NO3Cor e Forma:NeatPeso molecular:167.16Acetaminophen (1 mg/mL in Methanol)
CAS:Produto ControladoFórmula:C8H9NO2Cor e Forma:Single SolutionPeso molecular:151.16rac 2-(4-Formylphenyl)propionic Acid (Ibuprofen Impurity K)
CAS:<p>Impurity Ibuprofen EP Impurity K<br>Applications rac 2-(4-Formylphenyl)propionic Acid (Ibuprofen EP Impurity K) is a degradation product of Ibuprofen arising from oxidative and thermal treatments. Ibuprofen impurity K.<br>References Heikkinen, L., et al.: Acta Pharm. Fenn., 92, 275 (1983), Vargas, F., et al.: Pharmazie, 11, 767 (1991), Lee, J., et al.: Pharm. Res., 9, S170 (1995),<br></p>Fórmula:C10H10O3Cor e Forma:White To Light YellowPeso molecular:178.184-Acetylamino-2-chlorophenol
CAS:Produto Controlado<p>Impurity Paracetamol EP Impurity C/ Acetaminophen impurity C<br>Applications 4-Acetylamino-2-chlorophenol is an impuirty of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C8H8ClNO2Cor e Forma:White To Light PurplePeso molecular:185.61Acetaminophen-cysteine
CAS:Produto ControladoFórmula:C11H14N2O3SCor e Forma:NeatPeso molecular:254.31Ketoprofen Ethyl Ester
CAS:Produto Controlado<p>Applications Ketoprofen ethyl ester is an impurity of Ketoprofen (K200800).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Borodkin, S., et al.: J. Pharm. Sci., 59, 481 (1970), Shanbag, V., et al.: J. Pharm. Sci., 81, 149 (1991), Khan, M., et al.: Eur. J. Med. Chem., 40, 371 (2005),<br></p>Fórmula:C18H18O3Cor e Forma:ColourlessPeso molecular:282.33Acetaminophen Dimer
CAS:<p>Applications Acetaminophen Dimer is an oxidatively couple dimer of Acetaminaphen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1). Acetaminophen Dimer along with other p-acetamidophenol analogs were used to determine peroxidase activities (2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Potter, D.W. et al.: Mol. Pharmacol., 29, 155 (1986) (3) Shiga, M. et al.: Anal. Sci., 11, 195 (1995)<br></p>Fórmula:C16H16N2O4Cor e Forma:NeatPeso molecular:300.314,5-Dimethyl-2-methoxyacetophenone
CAS:Fórmula:C11H14O2Pureza:95.0Cor e Forma:SolidPeso molecular:178.231Acetaminophen Glutathione-d3 Disodium Salt (~90%)
CAS:Produto ControladoFórmula:C18H19D3N4Na2O8SPureza:~90%Cor e Forma:Off-White To Dark BrownPeso molecular:503.45(R)-Apomorphine-10-sulfate
CAS:Produto ControladoFórmula:C17H17NO5SCor e Forma:NeatPeso molecular:347.39Ethyl-(5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic
CAS:<p>Ethyl (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic) is a molecule that can be used in the treatment of cardiac diseases. It is a cardiotonic agent that has been shown to shorten the duration of ventricular fibrillation and restore contractility. This drug also decreases the frequency and severity of angina pectoris and enhances coronary artery blood flow. The most effective dose for this drug is 1.5 mg per kg body weight. It is administered orally or intravenously and should not be used with fatty esters because it may cause hypotension. Ethyl (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic) has been shown to have an effect on metal coordination profiles as well as an activated form of the molecule.</p>Fórmula:C17H17O3NPureza:Min. 98 Area-%Cor e Forma:Off-White PowderPeso molecular:283.32 g/molParacetamol Impurity L
<p>Paracetamol Impurity L is a drug product that is used as an analytical standard for the impurity paracetamol. It is found in pharmaceuticals, such as acetaminophen, which is used to relieve pain and reduce fever. Paracetamol Impurity L is a natural compound and has been shown to be metabolically stable in humans. The CAS number for this compound is 619-25-4.</p>Fórmula:C16H16N2O4Pureza:Min. 95%Peso molecular:300.31 g/molAcetaminophen acetate
CAS:<p>Acetaminophen acetate is a cholinergic amine that binds to the active site of the enzyme acetylcholine esterase, preventing it from breaking down acetylcholine. Acetaminophen is used as a pain reliever and antipyretic agent. It is also used for its anti-inflammatory effects in the treatment of rheumatoid arthritis and other inflammatory conditions. Acetaminophen has been shown to have anticancer properties, which may be due to its ability to bind to cancer cells, inhibit their growth, and induce apoptosis. Acetaminophen acetate is also an acylation reaction product that can be isolated by liquid chromatography in phase with fluorescence properties.</p>Fórmula:C10H11NO3Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:193.2 g/mol5-Benzoyl-N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-2,3-dihydro-1H-pyrrolizine-1-carboxamide, racemic
CAS:<p>5-Benzoyl-N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-2,3-dihydro-1H-pyrrolizine-1-carboxamide is a drug product that is used in research and development. It is a synthetic compound with niche applications. It has been shown to be metabolized in animal studies and the metabolism pathways have been elucidated. The analytical impurity standard for this drug product is 5-(benzoylamino)-N-[2-(hydroxymethyl)propanoyl]-2,3,-dihydro-1H-pyrrolizine-1 -carboxamide. This compound can be custom synthesized and also has an HPLC standard available.</p>Fórmula:C19H22N2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:358.39 g/mol5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic
CAS:<p>5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic is a drug product that is used for the research and development of drugs. It is manufactured synthetically. This compound has been shown to be metabolized in rats and humans. Studies have also shown that this compound may be an impurity in other drugs. The use of 5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic can be found in the USP/NF as a HPLC standard or as an analytical reference standard.</p>Fórmula:C15H12BrO3NPureza:Min. 95%Peso molecular:334.16 g/molMethyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic
CAS:<p>Methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate is a particle that is used to treat cardiac arrhythmias. It has been shown to be effective as an antipyretic agent and may also have analgesic properties. Methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate is a white powder that melts at temperatures of about 300°C. This drug can be administered by inhalation in the form of a vaporized liquid. The particle size of this drug is typically less than 10 microns in diameter. Methyl 5-benzoyl-2,3-dihydro-1H pyrrolizine 1 carboxylate can be administered through the respiratory tract as an aerosol or nebulizer. The molecular weight of this</p>Fórmula:C16H15NO3Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:269.3 g/molAll-trans-retinol-d5
CAS:Produto Controlado<p>All-trans-retinol-d5 is a supplement that is used to protect the brain from oxidative damage and to help maintain healthy skin. It is an antioxidant that prevents free radicals from damaging cells and helps maintain the structural integrity of cell membranes. All-trans-retinol-d5 can be found in high concentrations in animal tissues, such as liver, lung, kidney, heart, brain, and eye. It can also be found in human urine. The presence of all-trans-retinol-d5 in urine has been correlated with neuroprotective effects. Retinol levels have been shown to be higher in children who are less obese than those who are obese or overweight. All-trans retinol has been shown to inhibit cancer cell proliferation and induce apoptosis by inhibiting protein synthesis at the level of transcription.</p>Fórmula:C20H25D5OPureza:(%) Min. 80%Cor e Forma:Clear Viscous LiquidPeso molecular:291.48 g/mol1-(4-Cyclopropylphenyl)ethanone
CAS:Fórmula:C11H12OPureza:97%Cor e Forma:LiquidPeso molecular:160.2165′-Bromo-2′-hydroxy-4′-methylacetophenone
CAS:Fórmula:C9H9BrO2Pureza:98%Cor e Forma:SolidPeso molecular:229.0731-(4-Isopropoxyphenyl)ethanone
CAS:Fórmula:C11H14O2Pureza:98%Cor e Forma:Liquid, No data available.Peso molecular:178.2313′-Fluoro-5′-(trifluoromethyl)acetophenone
CAS:Fórmula:C9H6F4OPureza:98%Cor e Forma:LiquidPeso molecular:206.14
![N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FA161245.webp&w=3840&q=75)
![5-Benzoyl-N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-2,3-dihydro-1H-pyrrolizine-1-carboxamide, race…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIB58063.webp&w=3840&q=75)
