Cetonas e Derivados
As cetonas são compostos orgânicos que contêm um grupo carbonilo (C=O) ligado a dois átomos de carbono, formando uma estrutura onde o grupo carbonilo é flanqueado por grupos alquila ou arila. Na farmacologia, as cetonas são utilizadas na formulação de APIs devido à sua capacidade de melhorar a solubilidade e a estabilidade dos princípios ativos. Algumas cetonas possuem propriedades anti-inflamatórias, analgésicas e antimicrobianas. Os derivados de cetonas incluem compostos nos quais o grupo carbonilo é modificado, como os enóis, que têm aplicações na síntese de fármacos e como intermediários químicos na produção de outros compostos bioativos. Os derivados de cetonas são utilizados no desenvolvimento de novos medicamentos, incluindo aqueles para o tratamento de doenças neurodegenerativas, distúrbios metabólicos e certos tipos de câncer, devido aos seus efeitos específicos sobre enzimas e processos celulares.
Foram encontrados 2391 produtos de "Cetonas e Derivados"
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(S)-(+)-Ibuprofen Propylene Glycol Ester
CAS:Produto ControladoFórmula:C16H24O3Cor e Forma:NeatPeso molecular:264.362,2-Dimethoxy-2-phenylacetophenone
CAS:<p>Applications 2,2-Dimethoxy-2-phenylacetophenone (cas# 24650-42-8) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C16H16O3Cor e Forma:White PowderPeso molecular:256.3016,17-Dehydro Capsaicin
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications A dehydrogenated metabolite of Capsaicin (C175680).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glinsukon, T., et al.: Toxicon, 18, 215 (1980), Obach, R., et al.: Drug Metab. Dispos., 29, 1599 (2001), Reilly, C., et al.: Toxicol. Sci., 73, 170 (2003),<br></p>Fórmula:C18H25NO3Cor e Forma:Off-White To BrownPeso molecular:303.4Nabumetone Dimer Impurity
CAS:Produto Controlado<p>Impurity Nabumetone Dimer Impurity<br>Applications An impurity in a Nabumetone (N200500) drug substance.<br>References Friedel, H., et al.: Drugs, 35, 504 (1988), Davies, N., et al.: Clin. Pharmacokinet., 33, 403 (1997),<br></p>Fórmula:C27H26O3Cor e Forma:NeatPeso molecular:398.49(±)-Ibuprofen-d3, Sodium Salt (α-methyl-d3)
CAS:Produto Controlado<p>Applications (±)-Ibuprofen-d3, Sodium Salt (alpha-methyl-d3) (CAS# 1219805-09-0) is a useful isotopically labeled research compound.<br></p>Fórmula:C13H14D3NaO2Cor e Forma:NeatPeso molecular:231.29Ketoprofen-13CD3 Methyl Ester
CAS:Produto Controlado<p>Applications An intermediate for the synthesis of Labelled Ketoprofen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Derewenda, Z., et al.: J. Mol. Biol., 227, 818 (1992), Grochulski, P., et al.: J. Biol. Chem., 268, 12843 (1993).<br></p>Fórmula:C1613CH13D3O3Cor e Forma:NeatPeso molecular:272.325-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic
CAS:<p>5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic (5BPC) is a drug that is used for the treatment of pain. It has been shown to be safe and effective in treating postoperative pain when given by intravenous infusion or as an oral tablet. 5BPC has minimal toxicity and is metabolized primarily by the liver with a half life of 2.6 hours. The drug has been found to have pharmacokinetic properties that allow it to be used safely in patients with hepatic impairment and in those recovering from abdominal surgery. 5BPC is a prodrug that undergoes biotransformation by esterases into its active form, pyrrolizidine alkaloid (PA). PA acts as a nonsteroidal anti-inflammatory agent and inhibits prostaglandin synthesis, which leads to analgesia. This drug also has minimal drug interactions because</p>Fórmula:C15H13O3NPureza:Min. 95%Peso molecular:255.27 g/molPelubiprofen
CAS:<p>Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.</p>Fórmula:C16H18O3Pureza:99.69%Cor e Forma:SolidPeso molecular:258.31(2-Amino-2-(hydroxymethyl)propane-3-ol-1-yl) (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate), racemic
<p>Racemic 2-amino-2-(hydroxymethyl)propane-3-ol-1-yl (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate) is a synthetic drug product. It is used in research and development as an impurity standard. It is also used to synthesize drug products, which are custom synthesis and not commercially available. The racemate is a metabolite of the natural compound "Lysergic acid" and has been studied for its effects on metabolism.</p>Fórmula:C19H22N2O5Pureza:Min. 95%Peso molecular:358.39 g/molN-(4-Hydroxyphenyl)propanamide
CAS:<p>The N-(4-hydroxyphenyl)propionamide (HPPA) is a synthetic drug that binds to the human liver. It has been shown to be effective in preventing implantation of fertilized eggs, and can be used as a diagnostic agent for determining the presence of HPPA in human liver tissue. HPPA is also used as a diluent for other drugs. The HPPA binds to chromatographic components and can be detected using electrochemical detection, which allows it to be used as a targetable probe for cancer research. HPPA is also used to study iontophoretic transport of ions across reconstituted membranes in vitro.</p>Fórmula:C9H11NO2Pureza:(%) Min. 97%Peso molecular:165.19 g/molN-(4-Hydroxyphenyl)acetamide sulfate-d3 sodium
CAS:Produto Controlado<p>Please enquire for more information about N-(4-Hydroxyphenyl)acetamide sulfate-d3 sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C8H6D3NO5S•NaPureza:Min. 95%Peso molecular:257.24 g/mol3-Carboxy-a-methyl-benzeneacetic acid
CAS:<p>3-Carboxy-a-methyl-benzeneacetic acid (3CMA) is an impurity in the synthesis of 3,4-methylenedioxyphenylacetone. It is a preservative that has been analysed as a potential source of contamination in pharmaceutical preparations. 3CMA has been shown to be effective at inhibiting the growth of bacteria, yeast and moulds. The analysis time for 3CMA is typically 8 hours or less. The parameters that are used to analyse 3CMA include the use of acetonitrile, optimal porosity and efficiency. The analytical methods used for 3CMA include chromatographic and chromolith methods.</p>Fórmula:C10H10O4Pureza:Min. 95%Peso molecular:194.18 g/molNabumetone dimer
CAS:<p>Nabumetone is a nonsteroidal anti-inflammatory drug that is metabolized by the liver to form a dimer. The major metabolite of nabumetone is the dimer, which has been used as an impurity standard for this drug. Nabumetone has been shown to inhibit prostaglandin synthesis, and its metabolites have been studied for their effects on various enzymes.</p>Fórmula:C27H26O3Pureza:Min. 95%Peso molecular:398.49 g/mol6-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, racemic
CAS:<p>6-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, racemic is a drug product that is used as an analytical standard in the development of new drugs. It is also used to study the metabolism of drugs. 6BPDC has been shown to inhibit bacterial growth by binding to DNA and RNA, thereby preventing transcription and replication. This metabolite can be synthesized in the laboratory.</p>Fórmula:C15H13NO3Pureza:Min. 95%Peso molecular:255.27 g/mol3-Chloro-4-hydroxyacetanilide
CAS:<p>3-Chloro-4-hydroxyacetanilide is a chemical compound that belongs to the class of acetanilides. It has long-term toxicity and is used as a drug substance in the production of aniline derivatives. 3-Chloro-4-hydroxyacetanilide has been shown to be carcinogenic in hamsters. The long term exposure to this chemical was shown to cause liver damage and increased incidence of tumours in rats. This drug also contains impurities and traces of chloride, chlorine, and thionyl chloride, which are toxic substances that can cause irritation or burns on contact with skin or eyes.</p>Fórmula:C8H8ClNO2Pureza:Min. 95%Peso molecular:185.61 g/molTramadol Related Compound A CIV ((RS,SR)-1-(3-Methoxyphenyl)-2-(dimethylaminomethyl)cyclohexanol hydrochloride)
CAS:Produto Controlado<p>Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function</p>Fórmula:C16H25NO2·HClCor e Forma:White PowderPeso molecular:263.18853Mavatrep
CAS:<p>Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can be used for studies about inflammatory pain.</p>Fórmula:C25H21F3N2OPureza:98.51% - 99.31%Cor e Forma:SolidPeso molecular:422.44Tramadol Hydrochloride CIV
CAS:Produto Controlado<p>Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function</p>Fórmula:C16H25NO2·HCICor e Forma:White Crystalline PowderPeso molecular:403.10083Meperidine Hydrochloride CII
CAS:Produto Controlado<p>Alfentanil (inn), anileridine (inn), bezitramide (inn), bromazepam (inn), difenoxin (inn), diphenoxylate (inn), dipipanone (inn), fentanyl (inn), etc.</p>Fórmula:C15H21NO2·HClCor e Forma:White Crystalline PowderPeso molecular:247.15723
