Derivados de Benzimidazol e Imidazol
O benzimidazol é um composto constituído por um anel benzênico fundido a um anel imidazólico, uma estrutura de cinco membros contendo dois átomos de nitrogénio. Os derivados de benzimidazol, como o albendazol, são conhecidos pela sua atividade antiparasitária e antifúngica, sendo utilizados no tratamento de infeções parasitárias e de algumas doenças parasitárias em animais e humanos. O imidazol, por sua vez, é uma estrutura de cinco membros com dois átomos de nitrogénio, presente em diversos compostos biologicamente ativos. Os derivados de imidazol, como o metronidazol, possuem propriedades antimicrobianas e antiparasitárias. Estes compostos também são utilizados na indústria farmacêutica para tratar infeções bacterianas, doenças parasitárias e algumas infeções fúngicas, além de terem aplicações na química orgânica como catalisadores.
Na CymitQuimica, oferecemos benzimidazóis e imidazóis de alta pureza para investigação em química medicinal, farmacologia e biotecnologia.
Foram encontrados 10354 produtos de "Derivados de Benzimidazol e Imidazol"
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Imidapril
CAS:<p>Imidapril: oral ACE & MMP-9 inhibitor, lowers blood pressure, useful in hypertension, diabetic nephropathy, heart failure.</p>Fórmula:C20H27N3O6Cor e Forma:SolidPeso molecular:405.44Ilaprazole
CAS:<p>Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.</p>Fórmula:C19H18N4O2SPureza:99.91%Cor e Forma:SolidPeso molecular:366.44Galantamine EP Impurity E-13C,d3 (N-Desmethyl Galanthamine-13C,d3)
Fórmula:C1513CH16D3NO3Peso molecular:277.34(R,R)-Galantamine EP Impurity A L-DPTTA Salt ((+)-Narwedine L-DPTTA Salt, (+)-Galanthaminone L-DPTTA Salt)
CAS:Fórmula:C17H21NO3·C20H18O8Peso molecular:287.36 386.36Efinaconazole
CAS:<p>Efinaconazole (KP-103)(KP-103) is an Azole Antifungal currently under development as a topical treatment for onychomycosis.</p>Fórmula:C18H22F2N4OPureza:97.34% - 98%Cor e Forma:SolidPeso molecular:348.39Varenicline dihydrochloride
CAS:<p>Varenicline dihydrochloride is a Selective α4β2 nicotinic acetylcholine receptor partial agonist.</p>Fórmula:C13H15Cl2N3Pureza:99.88% - 99.97%Cor e Forma:SolidPeso molecular:284.18Donepezil
CAS:<p>Donepezil (Aricept) is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE).</p>Fórmula:C24H29NO3Pureza:99.69%Cor e Forma:White Or Almost White Crystal PowderPeso molecular:379.49Sertaconazole nitrate
CAS:<p>Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.</p>Fórmula:C20H15Cl3N2OS·HNO3Pureza:98.66% - 99.65%Cor e Forma:SolidPeso molecular:500.78Acotiamide
CAS:<p>Acotiamide, an oral AChE inhibitor (IC50: 1.79μM), improves gastric motility, targeting functional dyspepsia.</p>Fórmula:C21H30N4O5SCor e Forma:SolidPeso molecular:450.55Propiverine
CAS:<p>Propiverine reduces muscle spasms by limiting calcium influx, targeting bladder smooth muscles, aiding OAB research.</p>Fórmula:C23H29NO3Cor e Forma:SolidPeso molecular:367.48Oxiconazole
CAS:<p>Oxiconazole is a broad-spectrum imidazole antifungal, inhibiting ergosterol biosynthesi by disrupting cytochrome P450 enzymes (lanosterol 14- α demethylase).</p>Fórmula:C18H13Cl4N3OPureza:99.99%Cor e Forma:SolidPeso molecular:429.13Cyclopentolate Hydrochloride
CAS:<p>Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively.</p>Fórmula:C17H26ClNO3Pureza:99.91%Cor e Forma:SolidPeso molecular:327.85Varenicline Tartrate
CAS:<p>Varenicline Tartrate (CP 526555-18) is a benzazepine derivative that functions as an ALPHA4/BETA2 NICOTINIC RECEPTOR partial agonist.</p>Fórmula:C13H13N3·C4H6O6Pureza:98.23% - 98.32%Cor e Forma:Tan SolidPeso molecular:361.35Benznidazol
CAS:<p>Benznidazol (Benznidazole)e has an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating</p>Fórmula:C12H12N4O3Pureza:99.53% - >99.99%Cor e Forma:SolidPeso molecular:260.25(R)-Lansoprazole
CAS:<p>(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor</p>Fórmula:C16H14F3N3O2SPureza:98.09% - 98.99%Cor e Forma:Brown SolidPeso molecular:369.36Fesoterodine
CAS:<p>Fesoterodine is an oral mAChR blocker (pKi: 7.3-8.0) for M1-M5, used to treat OAB.</p>Fórmula:C26H37NO3Pureza:97.1%Cor e Forma:SolidPeso molecular:411.58Fosravuconazole L-lysine ethanolate
CAS:<p>Fosravuconazole L-lysine ethanolate, a prodrug for ravuconazole, treats onychomycosis in Japan.</p>Fórmula:C31H40F2N7O8PSPureza:99.43%Cor e Forma:SolidPeso molecular:739.7Eberconazole Nitrate
CAS:<p>Eberconazole Nitrate (Ebernet) is an azole antifungal agent and broad-spectrum imidazole derivative.</p>Fórmula:C18H15Cl2N3O3Pureza:99.53%Cor e Forma:SolidPeso molecular:392.23Propiverine hydrochloride
CAS:<p>Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).</p>Fórmula:C23H30ClNO3Pureza:99.93%Cor e Forma:White Crystalling PowerPeso molecular:403.94Sulfamoxole
CAS:<p>Sulfamoxole (Sulfamoxol) is an antibacterial belonging to sulfonamide.</p>Fórmula:C11H13N3O3SPureza:97.8% - 99.41%Cor e Forma:SolidPeso molecular:267.3L-Hyoscyamine sulfate
CAS:<p>L-Hyoscyamine sulfate (Levsin Sulfate) is a belladonna alkaloid derivative and the levorotatory form of racemic atropine which exhibits anticholinergic effect.</p>Fórmula:C34H48N2O10SPureza:96.7% - 99.61%Cor e Forma:Long Orthorhombic Prisms From Acetone SolidPeso molecular:676.8Isoconazole nitrate
CAS:<p>Isoconazole nitrate (Fazol) (Travogen) is an azole antifungal reagent.</p>Fórmula:C18H14Cl4N2O·HNO3Pureza:99.47%Cor e Forma:White Crystals Or Crystalline PowderPeso molecular:479.14Aclidinium bromide
CAS:<p>Aclidinium bromide (LAS-W 330) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis.</p>Fórmula:C26H30NO4S2·BrPureza:99.53% - 99.69%Cor e Forma:SolidPeso molecular:564.55Ipratropium Bromide
CAS:<p>Ipratropium Bromide (Sch 1000) is an antagonist of muscarinic receptors and is used in COPD and asthma studies.</p>Fórmula:C20H30BrNO3Pureza:99.92%Cor e Forma:SolidPeso molecular:412.37Vonoprazan
CAS:<p>Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and</p>Fórmula:C17H16FN3O2SPureza:99.87% - 99.92%Cor e Forma:SolidPeso molecular:345.39Tetrazole
CAS:<p>Tetrazole (1H-TETRAZOLE) is the bioisoster of carboxylic acid, possess considerable antibacterial property.</p>Fórmula:CH2N4Pureza:99.66%Cor e Forma:White Crystalline SolidPeso molecular:70.053-Amino-1H-indazole-5-carboxylic acid
CAS:Fórmula:C8H7N3O2Pureza:95.0%Cor e Forma:SolidPeso molecular:177.163Thiabendazole-d4 (Major)
CAS:Produto ControladoFórmula:C10D4H3N3SCor e Forma:Off WhitePeso molecular:205.274-{[(1-methyl-1H-benzimidazol-2-yl)methyl]amino}benzoic acid
CAS:Pureza:95.0%Peso molecular:281.31500244140625Midazolam
CAS:Produto Controlado<p>Applications Anesthetic; anticonvulsant; sedative; hypnotic. Positive allosteric modulator of the GABAA receptor. Neuroprotective & Neuroresearch products.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Fórmula:C18H13ClFN3Cor e Forma:White To Off-WhitePeso molecular:325.77a-(Chloromethyl)-2,4-dichlorobenzyl Alcohol
CAS:Produto Controlado<p>Impurity Isoconazole Impurity 6<br>Applications α-(Chloromethyl)-2,4-dichlorobenzyl alcohol is used in the synthesis of monocyclic nitroimidazole analogs of econazole. Isoconazole Impurity 6.<br>References Lee, S., et al.: Bioorg. Med. Chem. Lett., 21, 1515 (2011);<br></p>Fórmula:C8H7Cl3OCor e Forma:NeatPeso molecular:225.5((R)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)((S)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)methanone
CAS:Produto Controlado<p>Impurity Solifenacin EP Impurity D<br>Applications ((R)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)((S)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)methanone is a possible impurity of solifenacin (S676700) which is a muscarinic M3 receptor antagoinst. Solifenacin is used in treatment of urinary incontinence.<br>References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006)<br></p>Fórmula:C31H28N2OCor e Forma:NeatPeso molecular:444.57(R)-4-Isopropyl-5,5-diphenyloxazolidin-2-one
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:281.3550109863281Metronidazole-d4
CAS:Produto Controlado<p>Applications Metronidazole-d4 is a labelled analog of Metronidazole (M338880). Used as an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen.<br>References Carballo, M., et al.: J. App. Toxicol., 29, 248 (2009), Leitsch, D., et al.: Mol. Microbiol., 72, 518 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Fórmula:C62H4H5N3O3Cor e Forma:Light YellowPeso molecular:175.18N-(2-CHLORO-5-METHOXYPYRIMIDIN-4-YL)-1H-INDAZOL-6-AMINE
CAS:Pureza:95.0%Peso molecular:275.70001220703125Mebendazole-d8
CAS:Produto Controlado<p>Applications Labelled Mebendazole (M200500). Anthelmintic (Nematodes).<br>References Al-Badr, A.A., et al.: Anal. Profiles Drug Subs., 16, 291 (1987)<br></p>Fórmula:C162H3H10N3O3Cor e Forma:NeatPeso molecular:298.31Omeprazole
CAS:Produto Controlado<p>Applications Omeprazole covalently binds to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Fórmula:C17H19N3O3SCor e Forma:White To Light BrownPeso molecular:345.42Benzhydrol-d5
CAS:Produto Controlado<p>Applications Intermediate in the preparation of labelled Modafinil (M482500).<br>References Kumar, C., et al.: Eur. J. Med. Chem., 44, 1223 (2009),<br></p>Fórmula:C13D5H7OCor e Forma:NeatPeso molecular:189.26Methyl 2-(1H-imidazol-1-yl)acetate
CAS:Fórmula:C6H8N2O2Pureza:95.0%Cor e Forma:SolidPeso molecular:140.142cis-[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-4-yl-methyl)-1,3-dioxolan-4-yl]methyl Methanesulfonate
CAS:<p>Impurity Itraconazole Impurity 16<br>Applications cis-[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-4-yl-methyl)-1,3-dioxolan-4-yl]methyl Methanesulfonate (Itraconazole Impurity 16) is an impurity in the synthesis of Itraconazole (I937500), an orally active antimycotic structurally related to Ketoconazole. Antifungal.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989);<br></p>Fórmula:C14H15Cl2N3O5SCor e Forma:NeatPeso molecular:408.257Tebuconazole-d9
CAS:Produto Controlado<p>Applications Isotope labelled Tebuconazole (T013000), which is an ergosterol biosynthesis inhibitor present in most pesticide formulations (1,2). Various uptake is observed in plants (3). Drinking water Contaminant Candidate List 3 - CCL 3 as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Grimalt S. et al.: Anal Bioanal Chem. 2015 Apr;407(11):3083-91 2. Gent, D. et al.: Plant Dis. 2003 May:87(5) p591-5973. Wang, C. et al.: Pest. Biochem. Physiol. 2007 Jan:87(1) p1-8<br></p>Fórmula:C16H13D9ClN3OCor e Forma:White To Light YellowPeso molecular:316.87N-(2-Hydroxyethyl)-5-methyl-1,2,4-oxadiazole-3-carboxamide
CAS:<p>Applications N-(2-Hydroxyethyl)-5-methyl-1,2,4-oxadiazole-3-carboxamide is a photolysis product of Metronidazole (M338880), an antibiotic.<br>References Moore, Douglas E., et al.: Radiation Phy. and Chem., 36(4), 547-50 (1990)<br></p>Fórmula:C6H9N3O3Cor e Forma:NeatPeso molecular:171.154(S)-4-Isopropyl-5,5-diphenyloxazolidin-2-one
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:281.3550109863281Carbamazepine-d2,15N
CAS:Produto ControladoFórmula:C15H10D2N15NOCor e Forma:Off White SolidPeso molecular:239.27Itraconazole Mono N-Oxide
Produto ControladoFórmula:C35H38Cl2N8O5Cor e Forma:NeatPeso molecular:721.63N-Ethyl-N-(4-picolyl)atropamide (>85%)
CAS:<p>Stability Light Sensitive<br>Applications N-Ethyl-N-(4-picolyl)atropamide is a major impurity of Tropicamide (T892650), a medication used to dilate the pupil.<br>References Stefanowicz, Zdzislawa, et al.: J. of Pharma. and Biomed. Analy., 49(2), 214-220 (2009)<br></p>Fórmula:C17H18N2OPureza:>85%Cor e Forma:NeatPeso molecular:266.34O-Hydroxyethyl Metronidazole
CAS:Produto Controlado<p>Applications O-Hydroxyethyl Metronidazole is the hydroxy ethyl analogue and impurity of the antiprotozoal agent Metronidazole (M338880). O-Hydroxyethyl Metronidazole as well as other 1-substituted-2-methyl-5-nitroimidazoles showed potential antitrichomonal activity.<br>References Kajfez, F. et al.: J. Med. Chem., 11, 167 (1968);<br></p>Fórmula:C8H13N3O4Cor e Forma:Yellowish SolidPeso molecular:215.213a,4,5,6-Tetrahydro Midazolam
CAS:Produto Controlado<p>Applications 3a,4,5,6-Tetrahydro Midazolam is an impurity of Midazolam (M343000), a drug used for the treatment of acute seizures and is also known to exhibit activities as an anticonvulsant, sedative, and hypnotic.<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984); Lahat, E., et al.: Br. Med. J., 321, 83 (2000); Sati, B., et al.: Acta Pharm., 63, 385 (2013);<br></p>Fórmula:C18H17ClFN3Cor e Forma:NeatPeso molecular:329.801-(4-(3-Amino-1H-indazol-4-yl)phenyl)-3-(2-fluoro-5-methylphenyl)urea
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:375.40701293945314-Cyanobenzyl Bromide
CAS:Produto Controlado<p>Applications A benzyl halide as postemergence herbicides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Singer, G.M., et al.: J. Med. Chem., 26, 309 (1983),<br></p>Fórmula:C8H6BrNCor e Forma:NeatPeso molecular:196.04
![4-{[(1-methyl-1H-benzimidazol-2-yl)methyl]amino}benzoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF314477.webp&w=3840&q=75)
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![[4-(1h-1,3-benzodiazol-2-yl)phenyl]methanamine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF669356.webp&w=3840&q=75)
