Derivados de Benzimidazol e Imidazol
O benzimidazol é um composto constituído por um anel benzênico fundido a um anel imidazólico, uma estrutura de cinco membros contendo dois átomos de nitrogénio. Os derivados de benzimidazol, como o albendazol, são conhecidos pela sua atividade antiparasitária e antifúngica, sendo utilizados no tratamento de infeções parasitárias e de algumas doenças parasitárias em animais e humanos. O imidazol, por sua vez, é uma estrutura de cinco membros com dois átomos de nitrogénio, presente em diversos compostos biologicamente ativos. Os derivados de imidazol, como o metronidazol, possuem propriedades antimicrobianas e antiparasitárias. Estes compostos também são utilizados na indústria farmacêutica para tratar infeções bacterianas, doenças parasitárias e algumas infeções fúngicas, além de terem aplicações na química orgânica como catalisadores.
Na CymitQuimica, oferecemos benzimidazóis e imidazóis de alta pureza para investigação em química medicinal, farmacologia e biotecnologia.
Foram encontrados 10373 produtos de "Derivados de Benzimidazol e Imidazol"
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Oxcarbazepine
CAS:<p>Applications A metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug. A keto derivative of Carbamazepine. Used as an anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Dam., M., et al.: Epilepsy Res., 3, 70 (1989); Beydoun, A., et al.: Expert Opin. Pharmacother., 3, 59 (2001);<br></p>Fórmula:C15H12N2O2Cor e Forma:Light YellowPeso molecular:252.272,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
CAS:Produto Controlado<p>Applications Varenicline intermediate.<br>References Coe, J., et al.: J. Med. Chem., 48, 3474 (2005),<br></p>Fórmula:C13H14F3N3OCor e Forma:NeatPeso molecular:285.263-(2,3-Dichlorobenzamido) Lamotrigine
CAS:<p>Impurity Lamotrigine EP Impurity F/ Lamotrigine Related Compound D<br>Stability Light Sensitive<br>Applications 3-(2,3-Dichlorobenzamido) Lamotrigine (Lamotrigine EP Impurity F) an impurity of the anticonvulsant Lamotrigine (L173250).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Emami, J. et al.: J. Pharmac. Biomed. Anal., 40, 999 (2006); Srinivasulu, P. et al.: Chromatographia, 70, 271 (2009);<br></p>Fórmula:C16H9Cl4N5OCor e Forma:NeatPeso molecular:429.093-Hydroxy Carbamazepine
CAS:<p>Applications A metabolite of Carbamazepine (C175840).<br>References Park, B., et al.: Biochem. Pharmacol., 36, 581 (1987), Yamazaki, H., et al.: Drug Metab. Dispos., 27, 1260 (1999), Dieckhaus, C., et al.: Chem. Res. Toxicol., 14, 958 (2001),<br></p>Fórmula:C15H12N2O2Cor e Forma:NeatPeso molecular:252.272-Mercapto-4,5,6,7-d4-benzimidazole
CAS:Produto ControladoFórmula:C72H4H2N2SCor e Forma:NeatPeso molecular:154.23Tebuconazole-d9
CAS:Produto Controlado<p>Applications Isotope labelled Tebuconazole (T013000), which is an ergosterol biosynthesis inhibitor present in most pesticide formulations (1,2). Various uptake is observed in plants (3). Drinking water Contaminant Candidate List 3 - CCL 3 as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Grimalt S. et al.: Anal Bioanal Chem. 2015 Apr;407(11):3083-91 2. Gent, D. et al.: Plant Dis. 2003 May:87(5) p591-5973. Wang, C. et al.: Pest. Biochem. Physiol. 2007 Jan:87(1) p1-8<br></p>Fórmula:C16H13D9ClN3OCor e Forma:White To Light YellowPeso molecular:316.87TRAM-34
CAS:Produto Controlado<p>Applications TRAM-34 blocks intermediate conductance calcium-activated potassium channel IKCa1 with a Kd of 20nM and exhibits exquisite selectivity for the channel. Clotrimazole impurity.<br>References Wulff, H., et al.: J. of Biological Chemistry, 276, 34, 32040 (2001)<br></p>Fórmula:C22H17ClN2Cor e Forma:NeatPeso molecular:344.842-(benzylthio)-1H-benzimidazole
CAS:Pureza:95.0%Cor e Forma:Solid, White powderPeso molecular:240.32000732421875Imidacloprid-d4
CAS:Produto Controlado<p>Applications Imidacloprid-d4 is labelled Imidacloprid (I274990) which is a neonicotinoid, the active ingredient in certain neuro-active insecticides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Fórmula:C92H4H6ClN5O2Cor e Forma:WhitePeso molecular:259.69Oxazepam-d5
CAS:Produto Controlado<p>Applications Labelled Oxazepam. Anxiolytic; muscle relaxant (skeletal); anticonvulsant; ligand for the GABAA receptor benzodiazepinemodulatory site.Controlled substance (depressant).<br>References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Sisenwine, et al.: Arzneim. Forsch., 22, 682 (1972), Shearer, C.M., et al.: Anal. Profiles Drug Subs., 3, 441 (1974), Greenblatt, D.J., et al.: Clin. Pharmacokinet., 6, 89 (1981),<br></p>Fórmula:C152H5H6ClN2O2Cor e Forma:Off-WhitePeso molecular:291.74Tert-Butyl 6-(benzyloxy)-4-fluoro-1H-indazole-1-carboxylate
CAS:Pureza:95.0%Peso molecular:342.36999511718752-Methyl-5-nitroimidazole
CAS:<p>Impurity Tinidazole EP Impurity A/ Metronidazole EP Impurity A<br>Applications 2-Methyl-5-nitroimidazole (Tinidazole EP Impurity A) is a Floconazole impurity.<br>References Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009), Kumar, L., et al.: Eur. J. Med. Chem., 45, 817 (2010),<br></p>Fórmula:C4H5N3O2Cor e Forma:Light YellowPeso molecular:127.10Triazolam N-Oxide
CAS:Produto Controlado<p>Applications Triazolam N-Oxide is a derivative of Triazolam (T767380), a sedative.<br>References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976); Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978); Pakes, G.E., et al.: Drugs, 22, 81 (1981)<br></p>Fórmula:C17H12Cl2N4OCor e Forma:NeatPeso molecular:359.21Lifitegrast
CAS:Produto Controlado<p>Applications Lifitegrast is used for the treatment of signs and symptons of dry eye diseases. It also Inhibites corneal inflammation that is capable of causing pains, blurred vision and ocular discomfort in sufferer.<br>References Holland, E. J., et al.: Curr. Med. Res. Opin., 32, 1759 (2016); Sun, Y., et al.: J. Ocul. Pharmacol. Ther., 29, 395 (2013);<br></p>Fórmula:C29H24Cl2N2O7SCor e Forma:White To Off-WhitePeso molecular:615.48110-Acetoxy-5H-dibenz[b,f]azepine-5-carboxamide
CAS:Produto Controlado<p>Applications 10-Acetoxy-5H-dibenz[b,f]azepine-5-carboxamide is an intermediate in the synthesis of Oxacarbazepine (O869250) related compounds.<br></p>Fórmula:C17H14N2O3Cor e Forma:NeatPeso molecular:294.30Hydroxy Metronidazole
CAS:<p>Applications A metabolite of Metronidazole (M338880).<br>References Haller, I., et al.: Antimicrob. Agents Chemother., 22, 165 (1982), Gibson, R., et al.: Clin. Chem., 30, 784 (1984), Kuti, J., et al.: Pharmacotherapy, 25, 935 (2005),<br></p>Fórmula:C6H9N3O4Cor e Forma:WhitePeso molecular:187.15Rupatadine-d4 Fumarate
CAS:Produto Controlado<p>Applications Labelled Rupatadine (R701650). Rupatadine is a dual antagonist of histamine H1 and platelet-activating factor receptors. Rupatadine is used as an antihistaminic.<br>References Merlos, M., et al.: J. Pharmacol. Exp. Ther., 280, 114 (1997), Guadano, E.M., et al.: Allergy, 59, 766 (2004),<br></p>Fórmula:C30H26D4ClN3O4Cor e Forma:NeatPeso molecular:536.05Rufinamide-5-Carboxamide
CAS:Produto Controlado<p>Applications Rufinamide-5-Carboxamide is an impurity of Rufinamide (R701550) which is an antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Fórmula:C10H8F2N4OCor e Forma:NeatPeso molecular:238.19
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