Derivados de Benzimidazol e Imidazol
O benzimidazol é um composto constituído por um anel benzênico fundido a um anel imidazólico, uma estrutura de cinco membros contendo dois átomos de nitrogénio. Os derivados de benzimidazol, como o albendazol, são conhecidos pela sua atividade antiparasitária e antifúngica, sendo utilizados no tratamento de infeções parasitárias e de algumas doenças parasitárias em animais e humanos. O imidazol, por sua vez, é uma estrutura de cinco membros com dois átomos de nitrogénio, presente em diversos compostos biologicamente ativos. Os derivados de imidazol, como o metronidazol, possuem propriedades antimicrobianas e antiparasitárias. Estes compostos também são utilizados na indústria farmacêutica para tratar infeções bacterianas, doenças parasitárias e algumas infeções fúngicas, além de terem aplicações na química orgânica como catalisadores.
Na CymitQuimica, oferecemos benzimidazóis e imidazóis de alta pureza para investigação em química medicinal, farmacologia e biotecnologia.
Foram encontrados 10354 produtos de "Derivados de Benzimidazol e Imidazol"
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10-Methoxy-5H-dibenz[b,f]azepine-5-carbonyl chloride
CAS:Produto ControladoFórmula:C16H12ClNO2Cor e Forma:NeatPeso molecular:286.00Nitroguanidine (Wetted with water >20%)
CAS:Produto Controlado<p>Applications Nitroguanidine is used in the prediction of heats of detonation of energetic compounds from their molecular structure. It is also used in the synthetic preparation of imidacloprid-d4 (I274992), which is a neonicotinoid.<br> E0<br>References Keshavarz, M.H., et al.: Propellant, Explosives, Pyrotechnics, 37, 93 (2012); Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Fórmula:CH4N4O2Cor e Forma:White To Off-WhitePeso molecular:104.074,4'-(Bromomethylene)dibenzonitrile
CAS:Produto Controlado<p>Applications 4,4'-(1-Bromomethyl)bis-benzonitrile (CAS# 69545-39-7) is a useful research chemical compound.<br></p>Fórmula:C15H9BrN2Cor e Forma:NeatPeso molecular:297.1492-Cyclopropylmethylamino-5-chlorobenzophenone
CAS:Produto Controlado<p>Applications: 2-Cyclopropylmethylamino-5-chlorobenzophenone is a benzodiazepine derivative.<br>References Japp, M. et al.: J. Chrom., 439, 317 (1988); Guan, F. et al.: J. Anal Toxicol., 23, 54 (1999);<br></p>Fórmula:C17H16ClNOCor e Forma:NeatPeso molecular:285.772,5-Dichlorobenzoyl Cyanide
CAS:Produto Controlado<p>Applications 2,5-Dichlorobenzoyl Cyanide is a reagent applied for research purposes<br>References Veerareddy, A., et al.: J. Heterocyclic Chem., 51, 1311 (2014)<br></p>Fórmula:C8H3Cl2NOCor e Forma:NeatPeso molecular:200.022(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl methanesulfonate
CAS:Produto ControladoFórmula:C13H15F2N3O4SCor e Forma:NeatPeso molecular:347.34(2Z)-2-[Cyano(2,3-dichlorophenyl)methylene]hydrazinecarboximidamide
CAS:Produto ControladoFórmula:C9H7Cl2N5Cor e Forma:NeatPeso molecular:256.092-(Chloromethyl)-3,5-dimethylpyridine Hydrochloride
CAS:Produto Controlado<p>Applications Intermediate in the preparation of Omeprazole metabolites<br></p>Fórmula:C8H10ClN·ClHCor e Forma:NeatPeso molecular:192.094,4'-(1-Methylene) bis-Benzonitrile
CAS:Produto Controlado<p>Applications 4,4'-(1-METHYLENE) BIS-BENZONITRILE (cas# 10466-37-2) is a useful research chemical.<br></p>Fórmula:C15H10N2Cor e Forma:White To Off-WhitePeso molecular:218.25Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity
CAS:Produto Controlado<p>Applications Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity of Itraconazole (I937500). Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Fórmula:C34H36Cl2N8O5Cor e Forma:NeatPeso molecular:707.6110-Bromo-5H-dibenzo[b,f]azepine-5-carboxamide
CAS:Produto Controlado<p>Impurity Carbamazepine EP Impurity G<br>Applications 10-Bromo-5H-dibenzo[b,f]azepine-5-carboxamide is a Carbamazepine (C175840(P)) impurity, which has been used in treatment of pain associated with trigeminal neuralgia. It is an anticonvulsant, neuroprotective & neuroresearch product.<br>References Cry, T., et. al.: J. Assoc. Official Anal. Chem., 70, 836 (1987); Stenger, E.G., et al.: Med. Exp., 11, 191 (1964); Pynnonen, S., et al.: Ther. Drug Monit., 1, 409 (1979); Sidebottom, A., et al.: J. Clin. Pharm. Ther., 20, 31 (1995)<br></p>Fórmula:C15H11BrN2OCor e Forma:NeatPeso molecular:315.162,4-Dicyano-3-(2-methylpropyl)-pentanediamide (Mixture of Diastereomers)
CAS:Produto Controlado<p>Stability Hygrscopic<br>Applications 2,4-Dicyano-3-(2-methylpropyl)-pentanediamide is an impurity of Pregabalin (P704800), a GABA (A602920) analogue used as an anticonvulsant.<br>References Hoekstra, M.S., et al.: Org. Proc. Rec. Deve., 1, 26 (1997); Lowry, O., et al.: J. Biol. Chem., 193, 265 (1951); Gerlach, M., et al.: Brain Res., 741, 142 (1996); Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Fórmula:C11H16N4O2Cor e Forma:NeatPeso molecular:236.27cis-Hydroxy Solifenacin N-Oxide(Mixture of Diastereomers)
Produto Controlado<p>Applications Solifenacin (S676700) metabolite.<br></p>Fórmula:C23H26N2O4Cor e Forma:NeatPeso molecular:394.46rac-6-Chloro Voriconazole
CAS:Produto Controlado<p>Applications An achiral intermediate of Voriconazole (V760000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ferretti, R., et al.: Chromatographia, 47, 649 (1998),<br></p>Fórmula:C16H13ClF3N5OCor e Forma:NeatPeso molecular:383.76(R)-4,5-Dehydro Pregabalin
CAS:Produto Controlado<p>Applications (R)-4,5-Dehydro Pregabalin is derived from rac 4,5-Dehydro Pregabalin (D230050), which is an impurity of the anti-convulsnat, Pregabalin.<br>References Dousa, M, et al.: J. Pharmac. Biomed. Anal., 53, 717 (2010);<br></p>Fórmula:C8H15NO2Cor e Forma:NeatPeso molecular:157.21(2-Chlorophenyl)diphenylmethane
CAS:Produto Controlado<p>Applications (2-Chlorophenyl)diphenylmethane is a triarylmethane with antiproliferative activity. (2-Chlorophenyl)diphenylmethane is an impurity of the antifungal agent Clotrimazole (C587400).<br>References Al-Qawasmeh, R.A. et al.: Bioorg. Med. Chem. Lett., 14, 347 (2004);<br></p>Fórmula:C19H15ClCor e Forma:NeatPeso molecular:278.78Lurasidone Opened Imide (Mixture of Diastereomers)
CAS:Produto Controlado<p>Applications Lurasidone Opened Imide is an impurity in the synthesis of Lurasidone (L474920) which is antipsychotic used for treatment of schizophrenia.<br>References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007); Cole, P., et al.: Drugs of the Fut., 33, 316 (2008);<br></p>Fórmula:C28H38N4O3SCor e Forma:NeatPeso molecular:510.694,9-Diisobutyl-1,6-diazecane-2,7-dione
CAS:Produto Controlado<p>Applications 4,9-Diisobutyl-1,6-diazecane-2,7-dione is in impurity of rac-Pregabalin (P704800) which is a GABA analogue used as an anticonvulsant.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Fórmula:C16H30N2O2Cor e Forma:NeatPeso molecular:282.42Benzofuran-6-carboxylic Acid
CAS:Produto Controlado<p>Applications Benzofuran-6-carboxylic Acid is a reagent in the development of potent LFA-1/ICAM antagonist SAR 118 as an opthalmic solution for treating dry eyes. Preparation of piperidinylpyrimidine derivatives as inhibitors of HIV-1 LTR activation.<br>References Zhong, M., et al.: ACS Med. Chem., 3, 203 (2012); Fujiwara, N., et al.: Bioorg. Med. Chem., 16, 9804 (2008)<br></p>Fórmula:C9H6O3Cor e Forma:NeatPeso molecular:162.14Prazepam-d5
CAS:Produto Controlado<p>Applications Prazepam-d5, is the labeled analogue of Prazepam (P702250), a benzodiazepine derivative drug having anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties.<br>References Shader R. I., et al.: Ciba. Found. Symp., (74), 141 (1979); Jacqmin, P., et al.: Neuropsychobiology, 19 (4), 186 (1988);<br></p>Fórmula:C192H5H12ClN2OCor e Forma:NeatPeso molecular:329.83
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