Derivados de Purinas e Pirimidinas
As purinas possuem uma estrutura bicíclica, formada por um anel de seis membros fundido a um anel de cinco membros, ambos contendo átomos de nitrogênio em posições-chave. Os derivados das purinas, como a adenina e a guanina, são essenciais para a formação do DNA e RNA. Estes compostos possuem aplicações terapêuticas no tratamento do câncer e de doenças virais, pois inibem a replicação celular. As pirimidinas, por outro lado, possuem uma estrutura monocíclica de seis membros com dois átomos de nitrogênio. Seus derivados, como citosina, timina e uracila, também são componentes essenciais do DNA e RNA e são utilizados na quimioterapia e em tratamentos antivirais.
Na CymitQuimica, oferecemos derivados de purinas e pirimidinas para pesquisa em biologia molecular, genômica e desenvolvimento de terapias inovadoras.
Foram encontrados 8892 produtos de "Derivados de Purinas e Pirimidinas"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
5-Methyl-3-methylene-2-hexanone
CAS:Produto Controlado<p>Applications 5-Methyl-3-methylene-2-hexanone is an impurity of Tetrabenazine (T284000), an antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brossi, A., et al.: Helv. Chim. Acta, 43, 583 (1960);<br></p>Fórmula:C8H14OCor e Forma:NeatPeso molecular:126.204-(3,4-dimethylphenyl)-6-(2-fluorophenyl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:293.3450012207031N4-BENZYL-N2-(4-BROMOPHENYL)-5-FLUOROPYRIMIDINE-2,4-DIAMINE
Pureza:95.0%Peso molecular:373.229003906251-(1,3-Dioxolan-2-ylmethyl)-N-methyl-4-(methylamino)-1H-imidazole-5-carboxamide
CAS:Produto ControladoFórmula:C10H16N4O3Cor e Forma:NeatPeso molecular:240.26Uric Acid
CAS:<p>Applications Uric Acid is a heterocyclcic compound that is created when purine nucleotides are broken down of by the human body. High blood concetration of Uric Acid is known as hyperuricemia and is often associated with a wide range of disorders and medical conditions such as gout, diabetes and metabolic syndrome. Uric acid may be a marker of oxidative stress and may have a potential therapeutic role as an antioxidant.<br>References Heinig, M. et al.: Cle. Clin. J. Med., 73, 1059 (2006); Glantzounis, G.K. et al.: Curr. Pharmac. Des., 11, 4145 (2005); Dehghan, A. et al.: Diab. Care, 31, 361 (2008); Nakagawa, T. et al.: Am. J. Physiol. Renal Physiol., 290, F625 (2006);<br></p>Fórmula:C5H4N4O3Cor e Forma:NeatPeso molecular:168.11Aminopterin
CAS:<p>Impurity Methotrexate EP Impurity B<br>Applications Aminopterin (Methotrexate EP Impurity B) is a folic acid antagonist. Its actively transported into cells by thefolate transporter. In the cell, its converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, that, in turn, binds to dihydrofolate reductase and inhibits its activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Matherly, L.H., et al.: Cancer Res., 45, 1073 (1985), Rumberger, B.G., et al.: Cancer Res., 50, 4639 (1990), Roy, K., et al.: J. Biol. Chem., 273, 2526 (1998),<br></p>Fórmula:C19H20N8O5Cor e Forma:YellowPeso molecular:440.41Methyl Acetoacetate
CAS:Produto Controlado<p>Applications 3-Oxobutanoic Acid Methyl Ester is a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones.<br>References Ranu, B. et al.: J. Org. Chem. 65, 6270 (2000); Lu, J. et al.: Tetrahedron Lett., 41, 9075 (2000); Lu, J. et al.: Synlett., 1, 63 (2000);<br></p>Fórmula:C5H8O3Cor e Forma:NeatPeso molecular:116.121,3,7-Trimethyluric Acid
CAS:<p>Applications 1,3,7-Trimethyluric Acid is a caffeine derivative, and a methyl derivative of uric acid. Detected as a urine marker of caffeine consumption.<br>References Rothwell, J. et al.: PLoS One, 9, e93474 (2014); Silva, C. et al.: Sci. Trans. Med., 5, 197ra04 (2013);<br></p>Fórmula:C8H10N4O3Cor e Forma:Light Beige SolidPeso molecular:210.19Zebularine
CAS:Produto Controlado<p>Applications It is a cytidine analogue, cytidine deaminase inhibitor, and DNA demethylating agent.<br>References Driscoll, J., et al.: J. Med. Chem., 34, 3280 (1991), Ueki, T., et al.: Cancer Res., 60, 1835 (2000),Sherr, C., et al.: Cell, 116, 235 (2004), Dote, H., et al.: Clin. Cancer Res.,11, 4571 ( 2005),<br></p>Fórmula:C9H12N2O5Cor e Forma:NeatPeso molecular:228.205-Ethyl-2-methylpyridine(5-Ethyl-2-picoline)
CAS:<p>Applications Perfume composition.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hansen, B., et al.: Environ. Toxicol. Chem., 18, 772 (1999),<br></p>Fórmula:C8H11NCor e Forma:ColourlessPeso molecular:121.183-Methyluric Acid
CAS:<p>Applications 3-Methyluric Acid is a methylated derivative of uric acid that inhibits peroxynitrite-mediated oxidation, which has potential therapeutic application in the treatment of multiple sclerosis. 3-Methyluric Acid is also a known metabolite of Caffeine (C080100).<br>References Kean, R.B. et al.: J. Immunol., 165, 6511 (2000); Caubet, M.-S. et al.: J. Pharm. Biomed. Anal., 27, 261 (2002);<br></p>Fórmula:C6H6N4O3Cor e Forma:Light YellowPeso molecular:182.142,5-Pyridinedicarboxylic Acid
CAS:Produto Controlado<p>Applications Used in the preparation of new 2,5-pyridinedicarboxylic acids derivatives as antiviral agents.<br>References Pocker, Y., et al.: Biochemistry, 19, 2045 (1980), Flint, D., et al.: J. Biol. Chem., 268, 22369 (1993),<br></p>Fórmula:C7H5NO4Cor e Forma:NeatPeso molecular:167.121-Methyl-nicotinamide Iodide
CAS:Produto Controlado<p>Applications A nicotinic acid derivative which shows a dopaminergic neurotoxicity.<br>References Rollema, H., et al.: J. Med. Chem., 33, 2221 (1990),<br></p>Fórmula:C7H9IN2OCor e Forma:NeatPeso molecular:264.061-(4-Methoxyphenyl)-2-pyrimidin-4-ylethanone
CAS:Fórmula:C13H12N2O2Pureza:95.0%Cor e Forma:SolidPeso molecular:228.2514-(4-bromophenyl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:354.2510070800781
