Derivados de Purinas e Pirimidinas
As purinas possuem uma estrutura bicíclica, formada por um anel de seis membros fundido a um anel de cinco membros, ambos contendo átomos de nitrogênio em posições-chave. Os derivados das purinas, como a adenina e a guanina, são essenciais para a formação do DNA e RNA. Estes compostos possuem aplicações terapêuticas no tratamento do câncer e de doenças virais, pois inibem a replicação celular. As pirimidinas, por outro lado, possuem uma estrutura monocíclica de seis membros com dois átomos de nitrogênio. Seus derivados, como citosina, timina e uracila, também são componentes essenciais do DNA e RNA e são utilizados na quimioterapia e em tratamentos antivirais.
Na CymitQuimica, oferecemos derivados de purinas e pirimidinas para pesquisa em biologia molecular, genômica e desenvolvimento de terapias inovadoras.
Foram encontrados 8888 produtos de "Derivados de Purinas e Pirimidinas"
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3-(2-CHLOROPYRIMIDIN-4-YL)-1-(CYCLOPROPYLSULFONYL)-1H-INDOLE
Pureza:95.0%Peso molecular:333.79000854492191,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one (Ondansetron Impurity G)
CAS:Produto Controlado<p>Applications 1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one is an metabolite of Ondansetron (O655000), is a selective 5-hydroxytryptamine3 (5-HT3) receptor antagonist that has been introduced to clinical practice as an antiemetic for cancer treatment-induced and anesthesia-related nausea and vomiting.<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988), Faris, P..L., et al.: Lances, 355, 792 (2000), Ye, J.H., et al.: CNS Drug Reviews., 7, 199 (2001);<br></p>Fórmula:C17H17N3OCor e Forma:White To Off-WhitePeso molecular:279.344-(5-Chloro-1-isopropyl-1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:287.754-(3,4-dimethylphenyl)-6-(2-fluorophenyl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:293.34500122070312-[4-(3-chlorophenyl)piperazin-1-yl]-6-methyl-3,4-dihydropyrimidin-4-one
CAS:Pureza:98%Peso molecular:304.7799987792969Chloromethyl Propyl Carbonate
CAS:Produto Controlado<p>Applications Chloromethyl Propyl Carbonate (cas# 35273-90-6) is a compound useful in organic synthesis.<br></p>Fórmula:C5H9ClO3Cor e Forma:Colourless OilyPeso molecular:152.58Urea-urethane Compound (~85%)
CAS:Produto Controlado<p>Applications Urea-urethane Compound is a reaction product of 4,4'-sulfonylbis[benzenamine] and 2,4-TDI.<br></p>Fórmula:C42H36N6O8SPureza:~80%Cor e Forma:NeatPeso molecular:784.846-Methyl-2-methylsulfanyl-3H-pyrimidin-4-one
CAS:Pureza:98.0%Cor e Forma:Solid, CrystallinePeso molecular:156.1999969482422Fenclorim
CAS:Produto Controlado<p>Applications Herbicide safener.<br>References Lee, H., et al.: Eur. J. Med. Chem., 40, 862 (2005), Wright, S., et al.: Bioorg. Med. Chem. Lett., 17, 5638 (2007), Brazier-Hicks, M., et al.: J. Biol. Chem., 283, 21102 (2008), Vinggaard, A., et al.: Chem. Res. Toxicol., 21, 813 (2008),<br></p>Fórmula:C10H6Cl2N2Cor e Forma:BeigePeso molecular:225.07Tert-Butyl (6-(hydroxymethyl)pyrimidin-4-yl)carbamate
CAS:Pureza:95.0%Peso molecular:225.24800109863281-(1,3-Dioxolan-2-ylmethyl)-N-methyl-4-(methylamino)-1H-imidazole-5-carboxamide
CAS:Produto ControladoFórmula:C10H16N4O3Cor e Forma:NeatPeso molecular:240.26Uric Acid
CAS:<p>Applications Uric Acid is a heterocyclcic compound that is created when purine nucleotides are broken down of by the human body. High blood concetration of Uric Acid is known as hyperuricemia and is often associated with a wide range of disorders and medical conditions such as gout, diabetes and metabolic syndrome. Uric acid may be a marker of oxidative stress and may have a potential therapeutic role as an antioxidant.<br>References Heinig, M. et al.: Cle. Clin. J. Med., 73, 1059 (2006); Glantzounis, G.K. et al.: Curr. Pharmac. Des., 11, 4145 (2005); Dehghan, A. et al.: Diab. Care, 31, 361 (2008); Nakagawa, T. et al.: Am. J. Physiol. Renal Physiol., 290, F625 (2006);<br></p>Fórmula:C5H4N4O3Cor e Forma:NeatPeso molecular:168.113,5,3',5'-Tetraiodo Thyrolactic Acid (~90%)
CAS:Produto Controlado<p>Stability Hygroscopic, Temperature sensitive<br>Applications 3,5,3',5'-Tetraiodo Thyrolactic Acid is a thyroid hormone analogue. A Thyroxine (T425600) analogue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Horst, C., et al.: Biochem. J., 261, 945 (1989); Kvetny, J., et al.: Horm. Metab. Res., 24, 322 (1992); Yamauchi, K., et al.: J. Biol. Chem., 274, 8460 (1999); Davis, P., et al.: J. Endocrinol. Invest., 25, 377 (2002);<br></p>Fórmula:C15H10I4O5Pureza:~90%Cor e Forma:BeigePeso molecular:777.85N-Desmethyl Zolmitriptan
CAS:<p>Impurity Zolmitriptan USP Related Compound A<br>Stability Hygroscopic<br>Applications A metabolite of Zolmitriptan (Z639000). Zolmitriptan USP Related Compound A.<br>References Chen, J., et al.: J. Pharm. Biomed. Anal., 35, 639 (2004), Srinivasu, M., et al.: J. Pharm. Biomed. Anal., 37, 453 (2005),<br></p>Fórmula:C15H19N3O2Cor e Forma:NeatPeso molecular:273.33Methyl Acetoacetate
CAS:Produto Controlado<p>Applications 3-Oxobutanoic Acid Methyl Ester is a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones.<br>References Ranu, B. et al.: J. Org. Chem. 65, 6270 (2000); Lu, J. et al.: Tetrahedron Lett., 41, 9075 (2000); Lu, J. et al.: Synlett., 1, 63 (2000);<br></p>Fórmula:C5H8O3Cor e Forma:NeatPeso molecular:116.12
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