Derivados de Purinas e Pirimidinas
As purinas possuem uma estrutura bicíclica, formada por um anel de seis membros fundido a um anel de cinco membros, ambos contendo átomos de nitrogênio em posições-chave. Os derivados das purinas, como a adenina e a guanina, são essenciais para a formação do DNA e RNA. Estes compostos possuem aplicações terapêuticas no tratamento do câncer e de doenças virais, pois inibem a replicação celular. As pirimidinas, por outro lado, possuem uma estrutura monocíclica de seis membros com dois átomos de nitrogênio. Seus derivados, como citosina, timina e uracila, também são componentes essenciais do DNA e RNA e são utilizados na quimioterapia e em tratamentos antivirais.
Na CymitQuimica, oferecemos derivados de purinas e pirimidinas para pesquisa em biologia molecular, genômica e desenvolvimento de terapias inovadoras.
Foram encontrados 8892 produtos de "Derivados de Purinas e Pirimidinas"
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Allopurinol Sodium
CAS:<p>Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.</p>Fórmula:C5H4N4NaOPureza:99.93%Cor e Forma:SolidPeso molecular:159.1(S)-Tenofovir
CAS:<p>(S)-Tenofovir ((S)-PMPA) is the less active S-enantiomer of Tenofovir which is a nucleotide reverse transcriptase inhibitor.</p>Fórmula:C9H14N5O4PPureza:99.9%Cor e Forma:SolidPeso molecular:287.213,4-Dihydro naratriptan
CAS:<p>3,4-Dihydro naratriptan is a medicinal compound that is used as an anti-migraine drug. It is a hydrogenated form of the parent molecule naratriptan and has been shown to have a reaction time of about 30 minutes when catalyzed by palladium. The impurity, 3,4-dihydro naratriptan sulfonamide, has been found to be less potent than the target compound and can be eliminated from the synthesis by using catalytic hydrogenation. 3,4-Dihydro naratriptan sulfonamide can also be reduced by catalytic hydrogenation to yield 3,4-dihydro naratriptan.</p>Fórmula:C17H23N3O2SPureza:Min. 95%Peso molecular:333.45 g/molPemetrexed impurity C
CAS:<p>Pemetrexed is a drug product that belongs to the group of drugs called antifolate agents. It is used in the treatment of cancer and is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The impurity C is a natural metabolite that can be found in urine as well as in plasma. This impurity has not been identified as a major metabolite of pemetrexed.</p>Fórmula:C40H40N10O13Pureza:Min. 95%Peso molecular:868.81 g/molAllopurinol impurity E
CAS:<p>This product is a synthetic impurity of Allopurinol. It is a cyclization reaction product of dimethylhydrazine and allopurinol in the presence of an organic solvent such as DMF.</p>Fórmula:C7H9N3O3Pureza:Min. 95%Peso molecular:183.16 g/molMethotrexate-5-monomethyl ester
CAS:<p>Methotrexate-5-monomethyl ester is an analytical standard that is synthesized synthetically. The synthetic route used to produce the compound has been optimized for high purity, making this product suitable for use as a drug product or impurity standard. The structure of methotrexate-5-monomethyl ester was confirmed by 1H and 13C NMR spectroscopy and mass spectrometry. Methotrexate-5-monomethyl ester is an impurity found in the synthesis of methotrexate and is a metabolite of methotrexate. It has been shown to inhibit DNA synthesis and protein synthesis in animal cells, which may be due to its ability to inhibit transcription factors such as NFATc1, NFkB, STAT3, STAT5A and STAT5B.</p>Fórmula:C21H24N8O5Pureza:Min. 95%Peso molecular:468.47 g/molClopidogrel Impurity A
CAS:<p>Clopidogrel Impurity A is a medicine that is used for the prevention of heart attacks, strokes, and blood clots in people with an increased risk of these events. It is not intended to be used for immediate relief from sudden symptoms. Clopidogrel Impurity A is a substance that may be found in some preparations of clopidogrel. The presence of this substance can be detected by liquid chromatography-mass spectrometry (LC-MS/MS) methods. The structural analysis of this substance was determined using enantiomeric resolution and chromatographic methods. This impurity has been shown to have no effect on the bioavailability of the parent drug, clopidogrel, when given orally to Sprague-Dawley rats.</p>Fórmula:C15H15Cl2NO2SPureza:Min. 95%Peso molecular:344.26 g/mol2,4-Diamino-7-pteridinemethanol
CAS:<p>2,4-Diamino-7-pteridinemethanol (2,4-DPPM) is a drug product and an impurity found in the synthesis of 2,4-diamino-7-(2H)-pteridinone. 2,4-DPPM is a synthetic product that can be used as an analytical standard for the determination of aminopyrine in pharmaceuticals and other organic compounds. This compound has been used in pharmacological studies to investigate its effects on various enzymes associated with metabolism. It has also been used as an impurity standard for HPLC analysis of aminopyrine.</p>Fórmula:C7H8N6OPureza:Min. 95%Peso molecular:192.18 g/molZolmitriptan related compound D
CAS:<p>Zolmitriptan related compound D is a drug product that is an analytical impurity of the active ingredient, zolmitriptan. It is a synthetic compound and has been shown to be metabolized in vivo in humans. The chemical name for Zolmitriptan related compound D is 3-acetyl-5-(4-methoxyphenyl)-1H-indole-2,3-dione. This compound has been shown to have niche pharmacological properties that are not shared with other compounds in the same class, such as zolmitriptan.</p>Fórmula:C19H25N3O4Pureza:Min. 95%Peso molecular:359.42 g/mol5-[(Hydroxyacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide
CAS:<p>5-[(Hydroxyacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide is a drug product that was synthesized for research purposes. It is an analytical standard for HPLC and has not been approved for clinical use. 5-[(Hydroxylacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide is a compound with natural origin and has been classified as an API impurity. This synthetic drug product is custom synthesized to meet the requirements of pharmacopoeia standards.</p>Fórmula:C16H20I3N3O8Pureza:Min. 95%Peso molecular:763.06 g/mol5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP
CAS:<p>5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is an impurity found in the synthetic process of iopamidol. It is a nonionic chemical that has been shown to be synthesized using the following methods: dichloride and synthetic. 5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is used as a contrast agent for magnetic resonance imaging (MRI).</p>Fórmula:C14H18I3N3O6Pureza:Min. 95%Peso molecular:705.02 g/molTenofovir diphosphate
CAS:<p>TFV-DP inhibits DNA polymerases, mimics dATP, and is used by HIV-1's reverse transcriptase.</p>Fórmula:C9H16N5O10P3Cor e Forma:SolidPeso molecular:447.17Migalastat
CAS:<p>Migalastat (GR181413A free base) is an orally administered, competitive inhibitor of α-galactosidase A (α-Gal A), demonstrating an IC50 value of 0.04 μM against</p>Fórmula:C6H13NO4Cor e Forma:SolidPeso molecular:163.17Neopterin
CAS:<p>D-(+)-Neopterin (D-(+)-Neopterin) is produced by human monocytes/macrophages upon stimulation with the cytokine interferon-γ.</p>Fórmula:C9H11N5O4Pureza:99.54%Cor e Forma:SolidPeso molecular:253.21Palonosetron
CAS:<p>Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).</p>Fórmula:C19H24N2OPureza:98%Cor e Forma:SolidPeso molecular:296.41OXSI-2
CAS:<p>OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.</p>Fórmula:C18H15N3O3SPureza:98%Cor e Forma:Dark Orange SolidPeso molecular:353.39Ormetoprim
CAS:<p>Ormetoprim (Ro 5-9754), an antibiotic approved for use in the United States, is used to prevent the spread of disease in freshwater aquaculture.</p>Fórmula:C14H18N4O2Pureza:99.92%Cor e Forma:SolidPeso molecular:274.32Tenofovir exalidex
CAS:<p>Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant</p>Fórmula:C28H52N5O5PPureza:99.83%Cor e Forma:SolidPeso molecular:569.72Ergotamine Tartrate
CAS:Produto Controlado<p>Ergotamine and its salts</p>Fórmula:(C33H35N5O5)2·C4H6O6Cor e Forma:White Yellow PowderPeso molecular:1162.52764Codeine Phosphate CII
CAS:Produto ControladoConcentrates of poppy straw; buprenorphine (inn) codeinFórmula:C18H21NO3·H3O4PH2OCor e Forma:White Crystalline PowderPeso molecular:406.37 g/mol
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