Derivados de Purinas e Pirimidinas
As purinas possuem uma estrutura bicíclica, formada por um anel de seis membros fundido a um anel de cinco membros, ambos contendo átomos de nitrogênio em posições-chave. Os derivados das purinas, como a adenina e a guanina, são essenciais para a formação do DNA e RNA. Estes compostos possuem aplicações terapêuticas no tratamento do câncer e de doenças virais, pois inibem a replicação celular. As pirimidinas, por outro lado, possuem uma estrutura monocíclica de seis membros com dois átomos de nitrogênio. Seus derivados, como citosina, timina e uracila, também são componentes essenciais do DNA e RNA e são utilizados na quimioterapia e em tratamentos antivirais.
Na CymitQuimica, oferecemos derivados de purinas e pirimidinas para pesquisa em biologia molecular, genômica e desenvolvimento de terapias inovadoras.
Foram encontrados 8901 produtos de "Derivados de Purinas e Pirimidinas"
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Acetaldehyde 2,4-Dinitrophenylhydrazone
CAS:<p>Stability Hygroscopic<br>Applications Acetaldehyde 2,4-Dinitrophenylhydrazone is a dinitrophenylhydrazone (DNPH) derivative of an aliphatic alldehyde found in mainstream cigarette smoke. Dyes and metabolites.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zwiener, C. et al.: Anal. Bioanal. Chem., 372, 615 (2002); Delgado, B. et al.: J. Liq. Chrom. Rel. Technol., 31, 361 (2008); Miller, J.H. et al.: J. Chrom. Sci., 48, 12 (2010);<br></p>Fórmula:C8H8N4O4Cor e Forma:YellowPeso molecular:224.172-CHLORO-N-(4-CHLOROPHENYL)-9-METHYL-9H-PURIN-6-AMINE
CAS:Pureza:95.0%Peso molecular:294.1400146484375Methotrexate a-tert-Butyl Ester
CAS:Produto Controlado<p>Applications Methotrexate α-tert-Butyl Ester is an intermediate to the synthesis of folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.<br>References Yoshii, T., et al.: J. Am. Chem. Soc., 136, 16635 (2014);<br></p>Fórmula:C24H30N8O5Cor e Forma:NeatPeso molecular:510.5464,6-Dihydroxypyrazolo[3,4-d]pyrimidine
CAS:Produto Controlado<p>Stability Hygroscoipic<br>Applications 4,6-Dihydroxypyrazolo[3,4-d]pyrimidine is a major metabolite of Allopurinol (A547300). It is a xanthine oxidase inhibitor.<br>References Pacher, P., et al.: Pharmacol. Rev., 58, 87 (2006); Marro, P., et al.: Brain Res., 650, 9 (1994); Abramov, A., et al.: J. Neurosci., 27, 1129 (2007); Day, R., et al.: Clin. Pharmacokinet., 46, 623 (2007);<br></p>Fórmula:C5H4N4O2Cor e Forma:Off White SolidPeso molecular:152.11Ethyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate
CAS:Pureza:95.0%Cor e Forma:Liquid, No data available.Peso molecular:334.37899780273441-phenyl-5-[(pyrimidin-2-ylsulfanyl)methyl]-1H-1,2,3-triazole-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:313.33999633789062,3-Diamino-6-(trifluoromethyl)-4(3H)-pyrimidinone
CAS:Fórmula:C5H5F3N4OPureza:99.0%Cor e Forma:SolidPeso molecular:194.1172-[5-amino-3-(2-furyl)-1H-pyrazol-1-yl]-5,6-dimethylpyrimidin-4(3H)-one
CAS:Pureza:95.0%Peso molecular:271.2799987792969(R)-9-[2-(Diethylphosphonomethoxy)propyl] Adenine
CAS:Produto Controlado<p>Applications A acyclic phosphonate nucleotide.<br></p>Fórmula:C13H22N5O4PCor e Forma:White SolidPeso molecular:343.323-[(Dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-4H-carbazol-4-one Hydrochloride
CAS:Produto Controlado<p>Impurity Ondansetron EP Impurity A/ Ondansetron USP Related Compound A<br>Applications 3-[(Dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-4H-carbazol-4-one (Ondansetron EP Impurity A) is an impurity of Ondansetron (O655000), an antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mackinnon, J.W.M., et al.: Eur. J. Cancer Clin. Oncol., 25, 61 (1989);<br></p>Fórmula:C16H20N2O·ClHCor e Forma:NeatPeso molecular:292.806-Mercaptopurine Monohydrate
CAS:Produto Controlado<p>Applications An immunosuppressive drug used to treat leukemia. It is also used for pediatric non-Hodgkin’s lymphoma, polycythemia vera, and psoriatic arthritis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zeng, H., et al.: Biochem. Pharmacol., 68, 911 (2004),<br></p>Fórmula:C5H4N4S·H2OCor e Forma:YellowPeso molecular:170.19Mono-POC Isopropyl Tenofovir(Mixture of Diastereomers)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Tenofovir (T018500) impurity.<br></p>Fórmula:C17H28N5O7PCor e Forma:White SolidPeso molecular:445.41Tri-POC Tenofovir Dimer (>90%)
CAS:Produto Controlado<p>Stability Very Hygroscopic<br>Applications Tri-POC Tenofovir Dimer is a dimer of Tenofovir Disoproxil (T018505), an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral. It is also used in the preparation of phosphocitrate for the treatment of rheumatoid and osteoarthritis in the elderly.<br>References Turhanen, P. et al.: J. Org. Chem., 72, 1468 (2007);<br></p>Fórmula:C34H52N10O17P2Pureza:>90%Cor e Forma:White To Light BeigePeso molecular:934.78N-(9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:355.354003906251,3-Dimethyladamantane
CAS:<p>Impurity Memantine Related Compound A (1,3-Dimethyladamantane)<br>Applications 1,3-Dimethyladamantane is a dimethylated adamantane derivative. Memantine impurity A. Memantine Related Compound A (1,3-Dimethyladamantane).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C12H20Cor e Forma:NeatPeso molecular:164.294-(2H-1,3-benzodioxol-5-yl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:319.364013671875Methotrexate-d3 Heptaglutamate Trifluoroacetate
CAS:Produto ControladoFórmula:C50H61D3N14O23xC2HF3O2Cor e Forma:NeatPeso molecular:1232.142Methotrexate-d3
CAS:Produto Controlado<p>Applications Labelled Methotrexate (M260675). A Folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Fórmula:C20H19D3N8O5Cor e Forma:NeatPeso molecular:457.46Zeatin
CAS:<p>Applications Zeatin belongs to the family of plant-growth hormones called cytokinins and it can be used for agricultural use as agrochemicals for increasing crop yields and regulate various aspects of plant growth and development.<br>References Koprna, R., et al.: Bioorgan. Med. Chem., 24, 484-492 (2016)<br></p>Fórmula:C10H13N5OCor e Forma:White To Off-WhitePeso molecular:219.24Phenylhydrazine
CAS:Produto Controlado<p>Applications An aryl hydrazine used in the preparation of various dyes and pharmaceutical compounds. It is used in the investigation of oligosaccharides as well as the structure of photosystem II.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lattova, E. et al.: Meth. Mol. Biol., 534, 65 (2009); Anderson, L.B. et al.: J. Biol. Chem., 275, 4920 (2000);<br></p>Fórmula:C6H8N2Cor e Forma:Yellowish LiquidPeso molecular:108.142,5-Ethyl Acetate Febuxostat
CAS:Produto Controlado<p>Applications Febuxostat (F229000) is the parent compound for 2,5-Ethyl Acetate Febuxostat. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),<br></p>Fórmula:C20H25NO5SCor e Forma:NeatPeso molecular:391.482-Amino-6-(5-methylfuran-2-yl)-5-nitropyrimidin-4-yl 4-methylbenzenesulfonate
CAS:Pureza:97%Peso molecular:390.3699951171875Tenofovir Phosphate Diammonia Salt, >90%
CAS:Produto Controlado<p>Applications Tenofovir Phosphate Diammonia Salt is a metabolite of Tenofovir (T018500), an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br>References Michelson, A.M., et al.: Biochim. Biophys. Acta, 91, 1 (1964); Rosenberg, I., et al.: Collect. Czeck. Chem. Commun., 50, 1507 (1985); Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005),; Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006); Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)<br></p>Fórmula:C9H21N7O7P2Pureza:>90%Cor e Forma:NeatPeso molecular:401.25Tert-Butyl (6-(hydroxymethyl)pyrimidin-4-yl)carbamate
CAS:Pureza:95.0%Peso molecular:225.24800109863281-(3-Methylbut-2-en-1-yl)guanidine hydrochloride(1:x)
CAS:Pureza:97.0%Peso molecular:163.6499938964846-Methylpurine
CAS:Pureza:95.0%Cor e Forma:Solid, Light yellow solidPeso molecular:134.14199829101562Purine
CAS:Produto Controlado<p>Applications Purine (cas# 120-73-0) is a useful research chemical.<br></p>Fórmula:C5H4N4Cor e Forma:NeatPeso molecular:120.113,5-Dinitropyridine
CAS:Produto Controlado<p>Applications 3,5-Dinitropyridine is used as an azabenzyne pyrolytic precursor. The anion radical of 3,5-dinitropyridine aundergoes reversible dimerization reactions.<br>References Winkler, M., et al.: J. Am. Chem. Soc., 126, 6135 (2004); Macias-Ruvalcaba, N., et al.: J. Electroanal. Chem., 600, 294 (2007)<br></p>Fórmula:C5H3N3O4Cor e Forma:NeatPeso molecular:169.107-Methyl Memantine Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications 7-Methyl Memantine is an impurity of Memantine (HCl salt, M218000) which is used as an antiparkinsonian and antispasmodic.<br>References Rohde, H., et al.: Fortschr. Med., 100, 2023 (1982), Kornhuber, J., et al.: Eur. J. Pharmacol., 166, 589 (1989), Gortelmeyer, R. and Erbler, H.: Arzneimittel-Forsch., 42, 904 (1992)<br></p>Fórmula:C13H23N·ClHCor e Forma:White SolidPeso molecular:229.796-Methyl Nicotinic Acid
CAS:Produto Controlado<p>Applications A degradation product of Nicotinic acid (N429250). An impurity of Nicotinic acid.<br>References Ensign, J., et al.: Biol. Chem., 239, 2285 (1964), Houghton, C., et al.: Biochem. J., 130, 879 (1972),<br></p>Fórmula:C7H7NO2Cor e Forma:NeatPeso molecular:137.141,3,7-Trimethyluric Acid-d3
CAS:Produto Controlado<p>Stability Store in freezer<br>Applications A caffeine metabolite.<br>References Regal, K.A., et al.: J. of Chromatography B, 708, 75 (1998)<br></p>Fórmula:C82H3H7N4O3Cor e Forma:NeatPeso molecular:213.213-Des[2-(Dimethylamino)ethyl] Zolmitriptan 3-Acetic Acid
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications The indole acetic acid metabolite of Zolmitriptan (Z639000) formed by human hepatocytes.<br>References Wild, M.J. et al.: Xenobiotica, 29, 847 (1999);<br></p>Fórmula:C14H14N2O4Cor e Forma:NeatPeso molecular:274.27Methyl 4-((6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-yl)oxy)benzoate
CAS:Pureza:97.0%Peso molecular:324.33999633789064-(3-Butylureido)-2-methylbenzenesulfonylchloride
CAS:Fórmula:C12H17ClN2O3SPureza:98%Cor e Forma:SolidPeso molecular:304.791-((2R,3R,4S,5S)-3,5-DIFLUORO-4-HYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)PYRIMIDINE-2,4(1H,3H)-DIONE
Pureza:90.0%Peso molecular:264.18499755859375Orotic Acid-15N2 Monohydrate
CAS:<p>Applications Orotic Acid-15N2 Monohydrate is a labelled analogue of Orotic Acid Monohydrate (O691500(P)), which is used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.<br>References Furukawa, S.: PCT Int. Appl. (2009), WO 2009069291 A1<br></p>Fórmula:C5H415N2O4·H2OCor e Forma:NeatPeso molecular:177.09Memantine Glycine
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications An impurity of the antiparkinsonian and antispasmodic agent Memantine (M218000).<br>References Rystov, L. et al.: J. Pharmac. Biomed. Anal., 56, 887 (2011);<br></p>Fórmula:C14H23NO2Cor e Forma:NeatPeso molecular:237.34Tenofovir Alafenamide-d5 (Diastereomers)
CAS:Produto ControladoFórmula:C212H5H24N6O5PCor e Forma:NeatPeso molecular:481.501,3-dioxo-2-pyrimidin-2-ylisoindoline-5-carboxylic acid
CAS:Pureza:95.0%Peso molecular:269.21600341796875(S)-4-(4-Aminobenzyl)-2-(1H)-oxazolidinone
CAS:Produto Controlado<p>Impurity Zolmitriptan USP Related Compound G<br>Applications An intermediate of Zolmitriptan, as a novel inhibitor of the cytochrome P-450 enzyme aromatase. Zolmitriptan USP Related Compound G.<br>References Ahmed, S., et al.: Bioorg. Med. Chem. Lett., 5, 2789(1995), Ahmed, S., et al.: Drug. Des. Discov., 15, 239 (1998), Brodie, A., et al.: Steroids, 65, 171 (2000),<br></p>Fórmula:C10H12N2O2Cor e Forma:NeatPeso molecular:192.21
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