Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65630 produtos de "Derivados de Quinazolina e Quinolina"
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Tranilast
CAS:Produto Controlado<p>Applications Antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.<br>References Shiota, N., et al.: Brit. J. Pharmacol., 159, 626 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Kawabata, Y., et al.: Eur. J. Pharm. Sci., 39, 256 (2010),<br></p>Fórmula:C18H17NO5Cor e Forma:NeatPeso molecular:327.335-Methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-3-carboxylic acid
CAS:Peso molecular:210.23300170898438Palbociclib-d4
CAS:Produto Controlado<p>Applications Palbociclib-d4 is an isotope labelled compound of Palbociclib (P139900). Palbociclib (P139900) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.<br>References Finn, R., et al.: Breast Cancer Res., 11, 5 (2009)<br></p>Fórmula:C24H25D4N7O2Cor e Forma:Light YellowPeso molecular:451.565-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:314.3439941406255-Benzo[1,3]dioxol-5-yl-1 H -pyrazole-3-carboxylic acid
CAS:Cor e Forma:SolidPeso molecular:232.19500732421875Sulindac Acyl-β-D-Glucuronide
CAS:Produto Controlado<p>Applications Sulindac Acyl-β-D-Glucuronide is the major metabolite of the non-steroidal anti-inflammatory drug Sulindac (S699215) in plasma and urine.<br>References Hucker, H.B., et al.: Drug Metab. Dispos., 1, 721 (1973),<br></p>Fórmula:C26H25FO9SCor e Forma:NeatPeso molecular:532.534-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one
CAS:Produto Controlado<p>Applications Sitagliptin intermediate.<br>References Mohri, K., et al.: Chem. Pharm. Bull., 30, 3097 (1982), Cameron, M., et al.: J. Pharm. Biomed. Anal., 28, 137 (2002),<br></p>Fórmula:C16H12F6N4O2Cor e Forma:NeatPeso molecular:406.284'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxylic Acid
CAS:Produto Controlado<p>Impurity Telmisartan Bromo Acid Impurity<br>Applications An impurity of Telmisartan (D294250). An intermediate in the preparation of antihypertensive agents.<br>References Sharma, M.C. et al.: Adv. Appl. Sci, Res., 1, 120 (2010); Sharma, M.C. et al.: Int. J. Adv. Pharmac. Sci., 1, 249 (2010);<br></p>Fórmula:C14H11BrO2Cor e Forma:NeatPeso molecular:291.142-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:298.27301025390625Defluoro-6-chloro Norfloxacin Hydrochloride
CAS:Fórmula:C16H18ClN3O3·HClCor e Forma:Off-WhitePeso molecular:372.255-(6-Methoxynaphthalen-2-yl)-1H-pyrazole-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:268.2720031738281Dothiepin-d3
CAS:Produto Controlado<p>Stability Temperature Sensitive<br>Applications Labelled Dothiepin (D536500). A tricyclic antidepressant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Metysova, J., et al.: Arzneim.-Forsch., 13, 1039 (1963), Maguire, K.P., et al.: Br. J. Clin. Pharmacol., 12, 405 (1981), Donovan, S., et al.: Prog. Neuro-Psychopharmacol. Biol. Psychiatry, 18, 1143 (1994),<br></p>Fórmula:C19H18D3NSCor e Forma:NeatPeso molecular:298.46(R)-Rabeprazole Sodium Salt
CAS:Produto Controlado<p>Applications A partially reversible gastric proton pump inhibitor.<br>References Moda, T., et al.: Lett. Drug Des. Discov., 4, 502 (2007), Belaz, K., et al.: J. Pharm. Biomed. Anal., 47, 81 (2008),<br></p>Fórmula:C18H20N3NaO3SCor e Forma:NeatPeso molecular:381.42Ethylenediamine P-Toluenesulfonate
CAS:Produto Controlado<p>Impurity Xylometazoline EP Impurity E<br>Stability Hygroscopic<br>Applications Ethylenediamine P-Toluenesulfonate is a reactant used in the synthesis of antitumor agents. Also is an impurity of Xylometazoline (X749950), a vasoconstrictor involved in signal transduction, also used as a nasal decongestant. May be used in treatments involving ischemic injury due to the ability to shift energy metabolism from mitochondrial to glycolysis (2).<br>References 1. Fliri, A. et al.: J. Med. Chem. 2009 Dec 24;52(24):8038-46.2. Gohil, V. et al.: Nat Biotechnol. 2010 Mar;28(3):249-55.<br></p>Fórmula:C7H8O3S·C2H8N2Cor e Forma:NeatPeso molecular:232.29994-AMINO-3-CHLOROPICOLINIC ACID METHYL ESTER
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:186.600006103515623’-[3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone(Domperidone Impurity E) (>90%)
CAS:Fórmula:C32H34ClN7O3Pureza:>90%Cor e Forma:White To Off-WhitePeso molecular:600.113-(1-Benzyl-4-hydroxypiperidin-4-yl)-2-chloroquinoline
CAS:Pureza:98%Peso molecular:352.85998535156254”-trans-Hydroxy Cilostazol
CAS:Produto Controlado<p>Applications A metabolite of Cilostazol.<br>References de Morais, S., et al.: J. Biol. Chem., 269, 15419 (1994), Tata, P; J Pharm Biomed Anal 2001, 24, 381 ,Hiratsuka, M; Eur J Clin Pharmacol 2002, 58, 417 ,,Roy, J; Drug Metab Dispos 2005, 33, 884<br></p>Fórmula:C20H27N5O3Cor e Forma:NeatPeso molecular:385.46ent Atomoxetine-d3, Hydrochloride
CAS:Produto ControladoFórmula:C17H19D3ClNOCor e Forma:NeatPeso molecular:294.83Nitrofurantoin-13C3
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A nitrofuran labelled antibiotic with low resistance potential that is rapidly metabolized by mammals. Active against both Gram-positive and Gram-negative bacteria. Nitrofurantoin is also a prooxidant that is cytotoxic due to the generation of intracellular H2O2. Antibacterial.Environmental contaminants; Food contaminants; Heat processing contaminants<br>References Cadwallader, D.E., et al.: Anal. Profiles Drug Subs., 5, 345 (1976), Rogers, R.G., et al.: Am. J. Obstr. Gynecol., 191, 182 (2004),<br></p>Fórmula:C3C5H6N4O5Cor e Forma:NeatPeso molecular:241.148-propyl-4-(pyridine-4-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:333.38800048828125Ofloxacin N-Oxide Acetic Acid Salt (Mixture of Diastereomers)
CAS:Produto Controlado<p>Applications A metabolite of Ofloxacin.<br>References Uematsu, T., et al.: Eur. J. Clin. Pharmacol., 40, 581 (1991), Uematsu, T., et al.: Ther. Drug Monit., 17, 101 (1995), Ballesteros, O., et al.: J. Pharm. Biomed. Anal., 30, 1103 (2002), Kitade, T., et al.: Chem. Pharm. Bull., 51, 53 (2003),<br></p>Fórmula:C18H20FN3O5·ClHCor e Forma:NeatPeso molecular:437.419Apixaban-d3
CAS:Produto Controlado<p>Applications Apixaban-d3 is labelled Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Fórmula:C25H22D3N5O4Cor e Forma:White To Off-WhitePeso molecular:462.521,3-Bis([1,1’-Biphenyl]-4-ylphenylmethyl)-1H-imidazolium Chloride
CAS:Produto Controlado<p>Impurity Bifonazole EP Impurity D<br>Applications 1,3-Bis([1,1’-Biphenyl]-4-ylphenylmethyl)-1H-imidazolium Chloride (Bifonazole EP Impurity D) is a Bifonazole (B383400), an anti-fungal agent used in the treatment of skin diseases. Causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.<br>References Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);<br></p>Fórmula:C41H33N2·ClCor e Forma:NeatPeso molecular:589.17Nifedipine Monoamide
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Nifedipine Monoamide is an impurity of Nifedipine (N457000); a dihydropyridine calcium channel blocker. Also used as an antihypertensive and antianginal.<br>References Zhu, P., et al.: Sepu, 30, 1026 (2012); Karancsi, T., et al.: Acta Pharm. Hung., 66, 21 (1996); Ali, S.L., et al.: Anal. Profiles Drug Subs., 18, 221 (1989); Soons, P.A., et al.: J. Pharm. Biomed. Anal., 9, 475 (1991); Brown, M.J., et al.: Lancet, 356, 366 (2000)<br></p>Fórmula:C16H17N3O5Cor e Forma:Orange SolidPeso molecular:331.32Silodosin
CAS:<p>Applications Silodosin is an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertrophy.<br>References (1) Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995) (2) Murata, S., et al.: J. Urol., 164, 578 (2000)<br></p>Fórmula:C25H32F3N3O4Cor e Forma:NeatPeso molecular:495.53Netupitant
CAS:Produto Controlado<p>Applications Netupitant is a potent and selective neurokinin-1 receptor (NK1) receptor antagonist. It is achiral and orally active.<br>References Hoffmann, T., et al.: Bioorg. Med. Chem. Lett., 16, 1362 (2006); Di Fabio, R., et al.: Bioorg. Med. Chem., 21, 6264 (2013)<br></p>Fórmula:C30H32F6N4OCor e Forma:NeatPeso molecular:578.59N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine Formamide Hydrochloride
CAS:Produto Controlado<p>Impurity Alfuzosin Hydrochloride EP Impurity E<br>Applications Alfuzosin (A532000) impurity. Alfuzosin (A532000) is an α1-Adrenoceptor antagonist structurally similar to Prozosin. Antihypertensive. Used in treatment of benign prostatic hypertrophy. (Alfuzosin Hydrochloride EP Impurity E )<br>References Ramage, A.G., et al.: Eur. J. Pharmacol., 129, 307 (1986), Deering, A.H.,: Brit. J. Clin. Pharmacol., 25, 417 (1988), Priolo, L.D., et al.: Eur. J. Clin. Pharmacol., 35, 25 (1988),<br></p>Fórmula:C15H21N5O3·HClCor e Forma:White To Off-WhitePeso molecular:319.37 + (36.46)Pimobendan-d3
CAS:Produto Controlado<p>Applications Pimobendan-d3, is the labeled analogue of Pimobendan (P447500), a cardiotonic agent.<br>References Yokota, S. et al.: Yakuri Chiryo, 20, 1143 (1992); Yamamoto, M. et al.: Kank. Igaku Ken. Nenpo, 47, 155 (1996); Matsumoto, A. et al.: Cardiovas. Drugs Ther., 12, 595 (1998);<br></p>Fórmula:C19H15D3N4O2Cor e Forma:White To Light YellowPeso molecular:337.39BUTYL 5,8-DIMETHYL-4-MORPHOLINOQUINOLINE-2-CARBOXYLATE
CAS:Pureza:95.0%Peso molecular:342.4389953613281Rac Albuterol-d9
CAS:Produto Controlado<p>Applications A labelled β2-adrenoceptor agonist. Bronchodilator; tocolytic.<br>References Miyagawa, N., et al.: Biol. Pharm. Bull., 31, 2260 (2008), Gonzalez-Munoz, C., et al.: Eur. J. Pharmacol., 607, 151 (2009), Kern, C., et al.: J. Med. Chem., 52, 1773 (2009),<br></p>Fórmula:C132H9H12NO3Cor e Forma:White To YellowPeso molecular:248.37Telmisartan-d7
CAS:Produto Controlado<p>Applications Labelled Telmisartan (T017000). Telmisartan is an angiotensin II receptor antagonist.<br>References Wienen, W. et al.: Br. J. Pharmacol., 110, 245 (1993); Neutel, J.M. et al: Adv. Therap., 15, 206 (1998);<br></p>Fórmula:C33H23D7N4O2Cor e Forma:NeatPeso molecular:521.663Mildronate-d3
CAS:Produto Controlado<p>Stability Very Hygroscopic<br>Applications Mildronate-d3 is the labeled analogue of Mildronate (M344450), a novel pharmaceutical composition based on a reverse transcriptase inhibitor and meldonium. May contain a significant amount of water.<br></p>Fórmula:C6H11D3N2O2Cor e Forma:White To Off-WhitePeso molecular:149.21Reduced Haloperidol-d4
CAS:Produto Controlado<p>Applications Labelled Haloperidol Metabolite II<br>References Cutroneo, P., et al.: J. Pharm. Biomed. Anal., 41, 333 (2006), Sheridan, R., et al.: J. Med. Chem., 50, 3173 (2007), Lee, I., et al.: Eur. J. Pharmacol., 578(2, 123 (2008), Entrena, J., et al.: Psychopharmacol., 205, 21 (2009),<br></p>Fórmula:C21H21D4ClFNO2Cor e Forma:White To Light YellowPeso molecular:381.9Aripiprazole-d8
CAS:Produto Controlado<p>Applications Aripiprazole-d8 is a deuterated version of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.<br>References Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998), Oshiro, Y., et al.: J. Med. Chem., 41, 658 (1998),<br></p>Fórmula:C232H8H19Cl2N3O2Cor e Forma:Off White SolidPeso molecular:456.43Methyl 2-(4-aminophenyl)quinoline-4-carboxylate
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:278.3110046386719Ref: 10-F721211
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarNoradrenalone Hydrochloride
CAS:Produto Controlado<p>Applications Noradrenalone Hydrochloride is an intermediate of Norepinephrine (N674500), an antagonist of dibutyryl cyclic AMP in the regulation of narcosis. Norepinephrine modulates human dendritic cell activation by altering cytokine release.<br>References Strobel, G., et. al.: Eur. J. Biochem., 176, 397 (1988); Piguet, P., et al.: J. Exp. Med., 173, 673 (1991); Hosoi, J., et al.: Nature, 363, 159 (1993); Elenkov, I., et al.: Pharmacol. Rev., 52, 595 (2000); Kaplan, D., et al.: Immunity, 23, 611 (2005)<br></p>Fórmula:C8H10ClNO3Cor e Forma:Dark Yellow To Dark BrownPeso molecular:203.62Butoxy Olopatadine Hydrochloride
CAS:Produto ControladoFórmula:C25H31NO3•HClCor e Forma:NeatPeso molecular:429.98(3-Methoxypyridin-4-yl)boronic acid hydrate
CAS:Fórmula:C6H10BNO4Pureza:95.0%Cor e Forma:SolidPeso molecular:170.96Methylchloroisothiazolinone/Methylisothiazolinone Mixture
CAS:<p>Methylchloroisothiazolinone/Methylisothiazolinone Mixture (Kathon 886MW),a preservative, activates MMPs in human bronchial epithelial cells.</p>Fórmula:C8H9ClN2O2S2Cor e Forma:SolidPeso molecular:264.753-(4-Ethoxy-3-methylphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde
CAS:Pureza:98%Peso molecular:306.3649902343751-Descarbamoyl-2-carbamoyl Methocarbamol
CAS:Produto Controlado<p>Applications An impurity of the muscle relaxant Methocarbamol (M225950) with lysosomal acid lipase inhibitory effects.<br>References Topliss, J., et al.: J. Med. Chem., 22, 1238 (1979); Rosenbaum, A.I. et al.: J. Med. Chem., 52, 5281 (2010);<br></p>Fórmula:C11H15NO5Cor e Forma:NeatPeso molecular:241.240Benzydamine N-Oxide
CAS:<p>Applications A metabolite of Benzydamine (B209950).<br>References Beaty, N., et al.: J. Biol. Chem., 255, 3817 (1980), Tugnait, M., et al.: Drug Metab. Dispos., 25, 524 (1997), Ubeaud, G., et al.: Eur. J. Pharm. Sci., 8, 255 (1999),<br></p>Fórmula:C19H23N3O2Cor e Forma:NeatPeso molecular:325.4(E/Z)-Tamoxifen-d5
CAS:Produto Controlado<p>Applications Mixture of labelled Tamoxifen and its (E)-isomer.<br></p>Fórmula:C26H24D5NOCor e Forma:Off White SolidPeso molecular:376.555-Ethyl-demethyl Lercanidipine
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications 5-Ethyl-demethyl Lercanidipine is an impurity of Lercanidipine (L179000), which is a dihydropyridine calcium channel blocker.<br>References Bianchi, G., et al.: Pharmacol. Res., 21, 193 (1989); Rimoldi, E., et al.: Acta Therap., 200, 23 (1994); Argekar, A., et al.: J. Pharm. Biomed. Anal., 21, 1137 (2000);<br></p>Fórmula:C37H43N3O6Cor e Forma:NeatPeso molecular:625.75N-Cyano-3-(cyanoamino)-N'-methyl-7,8-dithia-2,4,11-triazadodec-2-en-12-imidamide (Cimetidine Impurity)
CAS:Produto Controlado<p>Impurity Cimetidine EP Impurity H<br>Applications N-Cyano-3-(cyanoamino)-N'-methyl-7,8-dithia-2,4,11-triazadodec-2-en-12-imidamide (Cimetidine EP Impurity H) is an impurity of Cimetidine (C441650), an H2-receptor antagonist that is used for the treatment and prevention of stress-induced gastroduodenal lesions.<br>References Burland, W., et al.: Brit. J. Clin. Pharm., 2, 481 (1975); Kauffman, G. & Morton, I.: Gastroenterology, 75, 1099 (1978); Peura, D. & Johnson, L.: Ann. Int. Med., 103, 173 (1985)<br></p>Fórmula:C10H18N8S2Cor e Forma:Off-WhitePeso molecular:314.43N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-4-chloromethyl Benzamide
CAS:Produto Controlado<p>Applications Gleevec Impurity<br></p>Fórmula:C24H20ClN5OCor e Forma:Off WhitePeso molecular:429.902'-Hydroxy-3'-methoxyacetophenone
CAS:Produto Controlado<p>Applications 2'-Hydroxy-3'-methoxyacetophenone, is an intermediate used for he synthesis of various chemical compounds. It can be used for the synthesis of 4'-Hydroxy-3-methoxyflavones with potent antipicornavirus activity.<br>References Nadine, d. M., et al.: J. Med. Chem., 34, 736 (1991);<br></p>Fórmula:C9H10O3Cor e Forma:NeatPeso molecular:166.183-Amino-5-(4-benzyloxyphenyl)thiophene-2-carboxylic acid methyl ester
CAS:Pureza:99.0%Cor e Forma:SolidPeso molecular:339.4100036621094Kynurenic Acid
CAS:<p>Applications A product of L-Tryptophan metabolism, possessing neruoactive activity having antiexcitotoxic and anticonvulsant properties.<br>References Wejksza, K., et al.: Pharmacol. Rep., 61, 751 (2009), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Di Natale, B., et al.: Toxicol. Sci., 115, 89 (2010),<br></p>Fórmula:C10H7NO3Cor e Forma:NeatPeso molecular:189.17Granisetron Hydrochloride
CAS:Produto Controlado<p>Applications A specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor<br>References Kilpatrick, G.J., et al.: Nature, 330, 746 (1987), Durig, T., et al.: J. Pharm. Sci., 86, 1092 (1997), Yuasa, H., et al.: Chem. Pharm. Bull., 44, 1361 (1996),<br></p>Fórmula:C18H24N4O·ClHCor e Forma:NeatPeso molecular:348.875-Benzyl Benzydamine Hydrochloride
CAS:<p>Applications 5-Benzyl Benzydamine is an impurity of Benzydamine hydrochloride (B209950). Benzydamine impurity B.<br></p>Fórmula:C26H29N3O·ClHCor e Forma:NeatPeso molecular:435.99N-[4-Fluoro-3-(prop-2-enamido)phenyl]-1-(2-fluorophenyl)-1H-pyrazole-4-carboxamide
CAS:Pureza:98.0%Peso molecular:368.343994140625DL-Fenfluramine
CAS:Produto Controlado<p>Applications Anorectic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pinder, et al.: Drugs, 10, 241 (1975); Caccia, S., et al.: Eur. J. Clin. Pharmacol., 29, 221 (1985); Finner, N., et al.: Curr. Ther. Res., 38, 847 (1985);<br></p>Fórmula:C12H16F3NCor e Forma:NeatPeso molecular:231.26Loratadine
CAS:Produto Controlado<p>Applications A nonsedating-type histamine H1-receptor.<br>References Bruttmann, G., et al.: J. Allergy Clin. Immunol., 83, 411 (1989), Haria, M., et al.: Drugs, 48, 617 (1994)<br></p>Fórmula:C22H23ClN2O2Cor e Forma:WhitePeso molecular:382.88ETHYL 2-(3-METHYL-4-OXO-3,4-DIHYDROPHTHALAZIN-1-YL)ACETATE
CAS:Pureza:95.0%Peso molecular:246.26600646972656Ref: 10-F505729
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarEthionamide-d3
CAS:Produto Controlado<p>Applications Ethionamide-d3 is the isotope labelled analogue of Ethionamide (E890420), a antibacterial (tuberculostatic) agent.<br>References Banerjee, A., et al.: Science, 263, 227 (1994), Newton, G., et al.: J. Bacteriol., 178, 1990 (1996), Baulard, A., et al.: J. Biol. Chem., 275, 28326 (2000), Koledin, T., et al.: Arch. Microbiol., 178, 331 (2002), Cardoso, R., et al.: Antimicrob. Agents Chemother., 48, 3373 (2004),<br></p>Fórmula:C8H7D3N2SCor e Forma:NeatPeso molecular:169.266-(trifluoromethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione
CAS:Pureza:98%Peso molecular:230.145996093754-[[4-Fluoro-3-(1-piperazinylcarbonyl)phenyl]methyl]-1(2H)-phthalazinone
CAS:Produto ControladoFórmula:C20H19FN4O2Cor e Forma:Off-WhitePeso molecular:366.39Irbesartan-d6
CAS:Produto Controlado<p>Applications Irbesartan-d6 is deuterium labelled Irbesartan (I751000) which is an angiotensin II type 1 (AII1)-receptor antagonist.<br>References Gillis, J.C. and Markham, A.: Drugs, 54, 885 (1997); Chando, T.J., et al.: Drug. Metabol. Dispos., 26, 408 (1998),<br></p>Fórmula:C25D6H22N6OCor e Forma:White SolidPeso molecular:434.574’-Hydroxyphenyl Carvedilol-d3
CAS:Produto Controlado<p>Applications A labelled metabolite of Carvedilol (C184625). It is used in the treatment of hypertension.<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),<br></p>Fórmula:C242H3H23N2O5Cor e Forma:NeatPeso molecular:425.49Axitinib Iodo Tetrahydropyran
Produto Controlado<p>Applications Axitinib Iodo Tetrahydropyran is an analog of Axitinib (A794650). Axitinib (A794650) is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.<br>References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003);Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002); Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003);<br></p>Fórmula:C19H20IN3OCor e Forma:NeatPeso molecular:433.286[5-(4-Thiophen-2-yl-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-carbamic acid tert-butyl ester
Pureza:95.0%Peso molecular:357.429992675781253-(1,3-benzodioxol-5-yl)-1H-pyrazole
CAS:Pureza:95.0%Cor e Forma:Solid, Orange powderPeso molecular:188.186004638671883-Hydroxy-2-pyrone
CAS:Produto Controlado<p>Applications 3-Hydroxy-2-pyrone<br></p>Fórmula:C5H4O3Cor e Forma:NeatPeso molecular:112.08(R)-1-Boc-3-hydroxypiperidine
CAS:Produto Controlado<p>Applications (R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. (R)-1-Boc-3-hydroxypiperidine has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kikuchi, T., et. al.: J. Labelled Comptd. Rad., 44, 31 (2001); Isakovic, L., et. al.: Bioorg. Med. Chem. Lett., 19, 2742 (2009)<br></p>Fórmula:C10H19NO3Cor e Forma:NeatPeso molecular:201.26(1-Methyl-1H-benzo[d]imidazol-2-yl)(pyridin-4-yl)methanone
CAS:Pureza:95.0%Peso molecular:237.261993408203123-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-(3,5-difluorophenoxy)benzoic acid
CAS:Pureza:98%Peso molecular:649.630004882813Ref: 10-F867169
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar250mgA consultar5-p-Tolyl-1H-pyrazole-3-carboxylic acid methyl ester
CAS:Pureza:95.0%Peso molecular:216.240005493164065-(Dimethylaminomethyl)-2-furfuryl Alcohol Hydrochloride
CAS:Produto Controlado<p>Impurity Ranitidine EP Impurity F<br>Stability Hygroscopic<br>Applications 5-(Dimethylaminomethyl)-2-furfuryl Alcohol Hydrochloride (Ranitidine EP Impurity F) is an intermediate in the synthesis of Ranitidine hydrochloride (R120000).<br>References Salameh, A., et al.: J. Food Sci., 71, 10 (2006), Guerrieri, P., et al.: Pharm. Res., 24, 147 (2007),<br></p>Fórmula:C8H13NO2·ClHCor e Forma:BrownPeso molecular:191.66Clioquinol
CAS:Produto Controlado<p>Applications Clioquinol is used as an antiparasitic compound, known to induce apoptosis in leukemia and myeloma cells.<br>References Cao, B. et al.: J. Biol. Chem., 288, 34181 (2013); Chen, Z. et al.: Eur J. Med. Chem., 68, 454 (2013);<br></p>Fórmula:C9H5ClINOCor e Forma:NeatPeso molecular:305.50S-(-)-Sulpiride-d3
CAS:Produto Controlado<p>Applications Labelled S-(-)-Sulpiride (S689140). Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic.<br>References Pitre, D., et al.: Anal. Profiles Drug Subs., 17, 607 (1988), Wagstaff, A.J., et al.: CNS Drugs, 2, 313 (1994),<br></p>Fórmula:C152H3H20N3O4SCor e Forma:White To Light GreenPeso molecular:344.444-Chloromethyl-5-methyl-1,3-dioxol-2-one
CAS:Produto Controlado<p>Applications 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is an important reagent in the preparation of angiotensin II receptor antagonist such as Olmesratan Medoxomil (O550000). 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is also used in the preparation of prodrugs of ampicillin.<br>References Ikeda, S. et al.: Chem. Pharmac. Bull., 32, 4316 (1984); Wu, T. Yaox. Xueb., 41, 537 (2006);<br></p>Fórmula:C5H5ClO3Cor e Forma:NeatPeso molecular:148.54Leflunomide
CAS:Produto Controlado<p>Applications An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic (Merck Index).This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vrenken, T., et al.: J. Hepatol., 49, 799 (2008), Mazzucco, G., et al.: Clin. Nephrol., 70, 163 (2008), Davies, M., et al.: J. Med. Chem., 52, 2683 (2009),<br></p>Fórmula:C12H9F3N2O2Cor e Forma:NeatPeso molecular:270.211-(tert-Butoxycarbonyl)-4-(1H-pyrazol-1-yl)piperidine-4-carboxylic acid
CAS:Pureza:95%Peso molecular:295.3389892578125Ref: 10-F615383
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultar
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