Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65624 produtos de "Derivados de Quinazolina e Quinolina"
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PD-153,035
CAS:<p>M02324 - PD-153,035</p>Fórmula:C16H14ClN3O2Pureza:>98%Cor e Forma:SolidPeso molecular:315.7600097656254-(furan-2-yl)-6-(5-methylthiophen-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:257.30999755859375Tert-Butyl 1-oxo-4-(pyridin-3-yl)-2,8-diazaspiro[4.5]decane-8-carboxylate
CAS:Pureza:98%Peso molecular:331.41598510742193-Methyl-1H-indene-2-carboxylic acid
CAS:Pureza:97.0%Cor e Forma:SolidPeso molecular:174.19900512695312Ref: 10-F066538
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultar6,7-Bis(benzyloxy)-4-oxo-1,4-dihydroquinoline-3-carbonitrile
CAS:Pureza:98%Peso molecular:382.419006347656253-[6-(Trifluoromethyl)pyridin-3-yl]propanoic acid
CAS:Fórmula:C9H8F3NO2Pureza:95.0%Cor e Forma:SolidPeso molecular:219.1631-Methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbonyl chloride
CAS:Pureza:95.0%Peso molecular:212.559997558593755-Ethyl-thiophene-2-carboxylic acid hydrazide
CAS:Fórmula:C7H10N2OSPureza:95.0%Cor e Forma:SolidPeso molecular:170.232'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid-d4
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid-d4 is the isotope labelled analog of 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid (T308515); a transformation product of Valsartan (V095750) which is a nonpeptide angiotensin II AT1-receptor antagonist and antihypertensive. 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid is also referred to as Valsartan acid.<br>References Noedler, K., et al.: Water Res., 47, 6650 (2013); Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993); Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Fórmula:C14H6D4N4O2Cor e Forma:NeatPeso molecular:270.286-fluoro-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:259.299987792968752-(2,4-Dimethoxybenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Pureza:97.0%Peso molecular:320.35998535156251-[3-Chloro-5-(trifluoromethyl)pyrid-2-yl]-1,4-diazepane
CAS:Pureza:98.0%Cor e Forma:LiquidPeso molecular:279.69000244140625(6-bromo-2-methoxyquinolin-3-yl)(3-chloro-4-fluorophenyl)methanol
CAS:Pureza:95.0%Peso molecular:396.6400146484375DL-erythro Ritalinic Acid-d10 (Major)
CAS:Produto ControladoFórmula:C13H7D10NO2Cor e Forma:NeatPeso molecular:229.34L-Kynurenine-d4 [4-(2-aminophenyl-3,5-d2); 3,3-d2]
CAS:Produto Controlado<p>Applications L-Kynurenine-d4 [4-(2-aminophenyl-3,5-d2); 3,3-d2] is a useful isotopically labeled compound of L-Kynurenine (K661005)<br></p>Fórmula:C10D4H8N2O3Cor e Forma:NeatPeso molecular:212.24Ethyl 3-(4-Bromophenyl)-1-methyl1H-pyrazole-5-carboxylate
CAS:Fórmula:C13H13BrN2O2Pureza:95.0%Cor e Forma:SolidPeso molecular:309.163N-(3,4-Dimethoxyphenyl)-6,7-dimethoxyquinazolin-4-amine
CAS:Pureza:98%Peso molecular:341.367004394531257-(3-Chloropropoxy)-4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxyquinoline-3-carbonitrile
CAS:Pureza:97%Peso molecular:466.739990234375N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS:Produto Controlado<p>Applications N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a substance used in the identification of related substances in the degradation products of tofacitinib citrate using LC-MS technique for process monitoring and quality assurance. A reagent for the synthesis of Tofacitinib (CP-690,550), a Janus tyrosine kinase (JAK3) specific inhibitor.<br>References Wu, X., et al.: J. Pharm. Biomed. Anal., 143, 17 (2017); Marican, A., et al.: Tetrahedron Lett., 54, 5096 (2013)<br></p>Fórmula:C13H19N5Cor e Forma:WhitePeso molecular:245.322-methyl-2-(4-morpholinyl)propanoic acid hydrochloride hydrate
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:227.69000244140625Ethyl 1-(difluoromethyl)-5-methyl-1H-pyrazole-3-carboxylate
CAS:Pureza:97.0%Peso molecular:204.177001953125Lansoprazole N-Oxide
CAS:Produto Controlado<p>Impurity Lansoprazole EP Impurity A<br>Applications Lansoprazole N-Oxide (Lansoprazole EP Impurity A) is an impurity of Lansoprazole (L175000) formed during the bulk synthesis of the drug.<br>References Kubo, K., et al.: Chem. Pharm. Bull., 38, 2853 (1990), Barradell, L., et al.: Drugs, 44, 225 (1992), Aydogmus, Z., et al.: Acta Pharm. Sci., 48, 45 (2006),<br></p>Fórmula:C16H14F3N3O3SCor e Forma:NeatPeso molecular:385.36Raltegravir
CAS:Produto Controlado<p>Applications Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN.<br>References Hare, S., et al.: Proc. Natl. Acad. Sci. U. S. A., 107, 20057 (2010); Hicks, C., et al.: Clin. Infect. Dis., 48, 931 (2009); Moss, D., et al.: Antimicrob. Agents Chemother., 56, 3020 (2012); Hare, S., et al.: Mol. Pharmacol., 80, 565 (2011)<br></p>Fórmula:C20H21FN6O5Cor e Forma:NeatPeso molecular:444.42Ref: 10-F469542
1gA consultar2gA consultar5gA consultar10gA consultar100mgA consultar250mgA consultar500mgA consultarMinoxidil β-D-Glucuronide
CAS:Produto Controlado<p>Applications Minoxidil β-D-Glucuronide is a metabolite of Minoxidil (M345000), an antihypertensive and antialopecia agent. Minoxidil activates ATP-activated K+ channels.<br>References Thomas, R.C., et al.: J. Pharmaceut. Sci., 64, 1366 (1975),<br></p>Fórmula:C15H23N5O7Cor e Forma:White To BrownPeso molecular:385.372-((1-(4-Phenoxyphenoxy)propan-2-yl)oxy)pyridine
CAS:Pureza:99.0%Cor e Forma:SolidPeso molecular:321.37600708007811-(Morpholin-4-yl)-2-(piperazin-1-yl)ethane-1,2-dione
CAS:Pureza:98%Peso molecular:227.264007568359383-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide
CAS:Pureza:95.0%Peso molecular:353.20001220703125Ethyl 6-ethynylpicolinate
CAS:Fórmula:C10H9NO2Pureza:98%Cor e Forma:Liquid, No data available.Peso molecular:175.1872-[2-(Pyridin-4-yl)thiazol-4-yl]acetic acid
CAS:Fórmula:C10H8N2O2SCor e Forma:SolidPeso molecular:220.25Nifedipine
CAS:Produto Controlado<p>Applications Used as an antihypertensive and antianginal. A dihydorpyridine calcium channel blocker.<br>References Ali, S.L., et al.: Anal. Profiles Drug Subs., 18, 221 (1989), Soons, P.A., et al.: J. Pharm. Biomed. Anal., 9, 475 (1991), Brown, M.J., et al.: Lancet, 356, 366 (2000),<br></p>Fórmula:C17H18N2O6Cor e Forma:Light YellowPeso molecular:346.333-acetyl-6-chloro-4-(4-chlorophenyl)quinolin-2(1H)-one
CAS:Pureza:95.0%Peso molecular:332.17999267578125Lercanidipine 5-Desmethyl-5-Propyl Ester
CAS:<p>Applications Lercanidipine 5-Desmethyl-5-Propyl Ester is an impurity of the dihydropyridine calcium channel blocker Lercanidipine (L179000).<br></p>Fórmula:C38H45N3O6Cor e Forma:NeatPeso molecular:639.7804Brimonidine
CAS:<p>M02627 - Brimonidine</p>Fórmula:C11H10BrN5Pureza:95%Cor e Forma:Solid, Yellow powderPeso molecular:292.1400146484375[2-oxo-5-(trifluoromethyl)-1(2H)-pyridinyl]acetic acid
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:221.13499450683594Ref: 10-F314892
1gA consultar5gA consultar2.5gA consultar50mgA consultar100mgA consultar500mgA consultarRiluzole Dimer Impurity
Produto Controlado<p>Applications Riluzole Dimer Impurity is an impurity of Rifuzole (R510000), a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant. Neuroprotective agent.<br>References Mizoule, J., et al.: Neuropharmacology, 24, 767 (1985), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994)<br></p>Fórmula:C17H10F6N4O2S2Cor e Forma:NeatPeso molecular:480.411-(4-Methylphenyl)-4,4,4-trifluorobutane-1,3-dione
CAS:<p>Applications A Celecoxib (Celebrex) intermediate.<br>References Kujubu, D., et al.: J. Biol. Chem., 266, 12866 (1991), Penning, T., et al.: J. Med. Chem., 40, 1347 (1997), Prasit, P., et al.: Bioorg. Med. Chem. Lett., 9, 1773 (1999), Sorbera, L., et al.: Drugs Future, 26, 346 (2001),<br></p>Fórmula:C11H9F3O2Cor e Forma:White SolidPeso molecular:230.184-Fluorobenzoic acid
CAS:Produto Controlado<p>Applications 4-Fluorobenzoic acid<br></p>Fórmula:C7H5FO2Cor e Forma:NeatPeso molecular:140.11Cerdulatinib hydrochloride
CAS:<p>Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.</p>Fórmula:C20H28ClN7O3SPureza:99.85%Cor e Forma:SolidPeso molecular:4823-(2,4-dimethylphenyl)-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one
CAS:Pureza:98%Peso molecular:282.3599853515625Riluzole
CAS:<p>Applications A neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant. Neuroprotective agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mizoule, J., et al.: Neuropharmacology, 24, 767 (1985), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994)<br></p>Fórmula:C8H5F3N2OSCor e Forma:NeatPeso molecular:234.203-[3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone (Domperidone Impurity D)
CAS:<p>Impurity Domperidone EP Impurity D<br>Applications An impurity of the gastrokinetic and antinauseant drug Domperidone (D531100).<br></p>Fórmula:C32H34ClN7O3Pureza:>90%Cor e Forma:White To Off-WhitePeso molecular:600.11Bupivacaine
CAS:<p>Bupivacaine (AH-250) is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels</p>Fórmula:C18H28N2OPureza:99.83%Cor e Forma:SolidPeso molecular:288.43trans-Haloperidol N-Oxide
CAS:Produto Controlado<p>Applications trans-Haloperidol N-Oxide is the trans-isomer of Haloperidol N-Oxide (H103735), a metabolite of Haloperidol (H103700).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gorrod, J., et al.: Xenobiotica., 23, 495 (1993); Monser, L., et al.: J. Liquid. Chromatograph. Technol., 26, 261 (2003);<br></p>Fórmula:C21H23ClFNO3Cor e Forma:NeatPeso molecular:391.864-Phenyl-2-(pyridin-3-yl)thiazole
CAS:Pureza:95.0%Cor e Forma:Liquid, No data available.Peso molecular:238.30999755859375N-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)-6-nitroquinazolin-4-amine
CAS:Pureza:95.0%Peso molecular:461.8800048828125Ethyl 2-(2-(2-fluorophenoxy)acetamido)-4-methyl-5-(phenylcarbamoyl)thiophene-3-carboxylate
CAS:Pureza:98%Peso molecular:456.489990234375Tert-butyl4-[5-(4-amino-2-fluoro-phenoxy)-1-methyl-indazol-6-yl]pyrazole-1-carboxylate
CAS:Pureza:98%Peso molecular:423.447998046875Keto Bisoprolol Hydrochloride
CAS:Produto Controlado<p>Impurity Bisoprolol EP Impurity J<br>Applications An impurity of Bisoprolol (B510500). Bisoprolol ester Impurity<br>References Tattersfield, A.E., et al.: Br. J. Clin. Pharmacol., 18, 343 (1984); Kohli, R.S., et al.: Eur. Heart J., 6, 845 (1985); Zachariah, P.K., et al.: Clin. Ther., 15, 779 (1993);<br></p>Fórmula:C18H30ClNO5Cor e Forma:Off WhitePeso molecular:375.893-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol
CAS:Produto Controlado<p>Impurity Metoprolol EP Impurity D<br>Applications 3-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol (Metoprolol EP Impurity D) is a new byproduct detected in Metoprolol tartrate. Metoprolol (M338790) impurity.<br>References Erickson, M., et al.: J. Pharmac. Biomed. Anal., 13, 567 (1995),<br></p>Fórmula:C12H18O4Cor e Forma:WhitePeso molecular:226.271,2-Deshydro Praziquantel
CAS:Produto Controlado<p>Impurity Praziquantel USP Related Compound B<br>Applications 1,2-Deshydro Praziquantel is a related compound to Praziquantel (P702095), anthelmintic, effective against flatworms. Praziquantel USP Related Compound B.<br>References Kuhn, I., et al.: Bioorg. Med. Chem., 18, 7900 (2010), Wang, W., et al.: Parasitol., 137, 1905 (2010),<br></p>Fórmula:C19H22N2O2Cor e Forma:Off-White To BeigePeso molecular:310.397-(Morpholine-4-sulfonyl)-3-(propan-2-yl)-1,2,3,4-tetrahydroquinoxalin-2-one
CAS:Pureza:97%Peso molecular:339.41000366210942-(3-methoxyphenyl)-6-methylquinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:293.3219909667969tau-Fluvalinate (Mixture of Diastereomers)
CAS:<p>Applications τ-Fluvalinate is a synthetic pyrethroid aracacide. τ-Fluvalinate is commonly used to control Varroa jacobsoni (a parasitic mite) in honey bee colonies.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Delaplane, K.S. et al.: J. Econ. Entomol., 88, 1206 (1995); Ferrer-Dufol, M. et al.: J. Apicul. Res., 34, 147 (1995); Lindberg, C.M. et al.: J. Econ. Entomol., 93, 189 (2000);<br></p>Fórmula:C26H22ClF3N2O3Cor e Forma:Light YellowPeso molecular:502.9111-Hydroxy-N-methyl Dihydro Loratadine
CAS:<p>Impurity Loratadine USP Related Compound D<br>Stability Hygroscopic<br>Applications 11-Hydroxy-N-methyl Dihydroloratadine (Loratadine USP Related Compound D) is an impurity of Loratadine (L469575).<br>References Zhong, D., et al.: Pharmazie, 49, 736 (1994), Squella, J., et al.: Talanta, 43, 2029 (1996), Ruperez, F., et al.: J. Pharm. Biomed. Anal., 29, 35 (2002),<br></p>Fórmula:C20H23ClN2OCor e Forma:White To YellowPeso molecular:342.86(4-Bromo-5-cyclopropyl-3-trifluoromethyl-pyrazol-1-yl)-acetic acid
CAS:Fórmula:C9H8BrF3N2O2Pureza:95.0%Cor e Forma:SolidPeso molecular:313.074N-((4,6-dimethoxypyrimidin-2-yl)carbamoyl)-3-(trifluoromethyl)pyridine-2-sulfonamide
CAS:Pureza:98%Cor e Forma:SolidPeso molecular:407.3200073Tert-butyl (3S)-3-(1H-pyrazol-5-yl)azepane-1-carboxylate
CAS:Pureza:98%Peso molecular:265.35699462890625Orbifloxacin
CAS:<p>Applications Orbifloxacin is a fluoroquinolone antibiotic used in veterinary medicine, mainly for the treatment of staphylococcal infections in dogs.<br>References Ganiere, J.P. et al.: Res. Vet. Sci., 77, 67 (2004); Scott, D.W. et al.: Can. Vet. J., 47, 999 (2006); Rubin, J. et al.: Vet. Microbiol., 131, 164 (2008);<br></p>Fórmula:C19H20F3N3O3Cor e Forma:White To Light YellowPeso molecular:395.382-(((5-((Dimethylamino)methyl)furan-2-yl)methyl)thio)ethanamine Fumarate (2:1)
CAS:Produto Controlado<p>Impurity USP Ranitidine Related Compound A<br>Applications 2-(((5-((Dimethylamino)methyl)furan-2-yl)methyl)thio)ethanamine (E)-2-Butenedioate is an impurity of Ranitidine (R120000), a histamine H2-receptor antagonist which inhibits gastric acid secretion. Antiulcerative.<br>References Bradshaw, J., et al.: Brit. J. Pharmacol., 66, 464 (1979), Berstad, A., et al.: Scand. J. Gastroenterol, 15, 637 (1980), Hohnjec, M., et al.: Anal. Profiles Drug Subs., 15, 533 (1986),<br></p>Fórmula:C10H18N2OS·C4H4O4Cor e Forma:WhitePeso molecular:544.72764-CHLORO-1-(3-METHYLPYRIDIN-4-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDINE
CAS:Pureza:97.0%Peso molecular:245.66999816894538-ethyl-4-(thiophene-2-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:324.3999938964844N-(2-Aminoethyl)morpholine
CAS:Fórmula:C6H14N2OPureza:98%Cor e Forma:Solidified mass or fragmentsPeso molecular:130.191Paliperidone Z-Oxime
CAS:Produto Controlado<p>Applications Paliperidone Z-oxime is an impurity of Paliperidone (P141000), a known orally active antipsychotic agent.<br>References Rao, J., et al.: Pharmacia Lettre, 3, 240 (2011);<br></p>Fórmula:C23H28F2N4O3Cor e Forma:NeatPeso molecular:446.49N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide
CAS:Produto ControladoFórmula:C16H13Cl2N5OSCor e Forma:NeatPeso molecular:394.282-(2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDIN-6-YL)PROPAN-2-OL
CAS:Pureza:95.0%Peso molecular:313.799987792968753-Chloro-4-morpholino-1,2,5-thiadiazole
CAS:Produto Controlado<p>Impurity Timolol EP Impurity F; Timolol BP Impurity F; Timolol USP Related Compound F<br>Applications 3-Chloro-4-morpholino-1,2,5-thiadiazole (Timolol EP Impurity F; Timolol BP Impurity F; Timolol USP Related Compound F) is an intermediate for the synthesis of Timolol.<br>References Wasson, B., et al.: J. Med. Chem., 15, 651 (1972), Tokunaga, M., et al.: Sci., 277, 936 (1997),<br></p>Fórmula:C6H8ClN3OSCor e Forma:White To Off-WhitePeso molecular:205.67Dutasteride a-Dimer (~90%)
CAS:Produto Controlado<p>Applications Dutasteride α-Dimer is a dimer impurity of Dutasteride (D735000); a dual inhibitor of 5α-reductase isoenzymes type 1 and 2. Dutasteride is structurally related to Finasteride (F342000) and is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995); Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999); Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Fórmula:C46H55F6N3O4Pureza:~90%Cor e Forma:Off-WhitePeso molecular:827.94
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![2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid-d4](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FT308517.webp&w=3840&q=75)
![1-[3-Chloro-5-(trifluoromethyl)pyrid-2-yl]-1,4-diazepane](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF017269.webp&w=3840&q=75)
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![N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM296155.webp&w=3840&q=75)
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![3-[3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone (Domperidone Impurity D)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD449455.webp&w=3840&q=75)
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