Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65630 produtos de "Derivados de Quinazolina e Quinolina"
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N-Methyl-3-(1-naphthalenyloxy)-3-(3-thienyl) propanamine tartrate
<p>N-Methyl-3-(1-naphthalenyloxy)-3-(3-thienyl) propanamine tartrate is an impurity standard used for the quantitative analysis of norephedrine in pharmaceutical products. It is also a metabolite of methamphetamine, which has been shown to have anti-inflammatory activities.</p>Fórmula:C18H19NOS·C4H6O6Pureza:Min. 95%Peso molecular:447.5 g/molChlorhexidine digluconate impurity K dihydrochloride
CAS:<p>Chlorhexidine digluconate impurity K dihydrochloride is a drug product that is an analytical standard. It is a natural metabolite of chlorhexidine digluconate, which is a synthetic compound. Chlorhexidine digluconate impurity K dihydrochloride has been shown to have anti-inflammatory properties and to inhibit the production of prostaglandins in animal studies. The pharmacopoeia designation for this drug product is USP/NF.</p>Fórmula:C22H29Cl2N9OPureza:Min. 95%Cor e Forma:PowderPeso molecular:506.43 g/molCimetidine impurity F
CAS:<p>Cimetidine impurity F is a research and development, drug product, analytical, synthetic, natural, niche, HPLC standard and pharmacopoeia impurity.<br>CAS No. 55272-86-1</p>Fórmula:C16H24N8S2Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:392.55 g/mol5-Methoxy-2-[[(4-Chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole
CAS:<p>5-Methoxy-2-[(4-chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H benzimidazole is a synthetic drug product. It has been used as a positive control in metabolism studies and as an impurity standard. 5-Methoxy 2-[(4-chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfinyl]-5 methoxy 1H benzimidazole is also a metabolite of the active pharmaceutical ingredient (API) which is used to develop drugs. This chemical is synthesized by custom synthesis and can be obtained at high purity levels. The metabolite of this compound is 5 methoxy 2-[(4 chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfonyl]-5 methoxy 1H benzimidazole.</p>Fórmula:C16H16ClN3O2SPureza:Min. 95%Cor e Forma:PowderPeso molecular:349.84 g/molN-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroacetamide sodium salt
CAS:<p>2-Nitroacetamide sodium salt is an impurity of the drug N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroacetamide, a synthetic chemotherapeutic agent for the treatment of cancers. This compound has been shown to have metabolism studies and natural properties. It has a CAS number of 112251-56-6 and is found in the pharmacopoeia. 2-Nitroacetamide sodium salt is a custom synthesis that can be used as a reference standard for HPLC analysis. It can also be used as a drug product or metabolite in drug development.</p>Fórmula:C12H18N3O4SNaPureza:Min. 95%Cor e Forma:PowderPeso molecular:323.34 g/mol3-[Methyl(phenylmethyl)amino]-1-phenyl-1-propanone hydrochloride
CAS:<p>Nisoxetine is a norepinephrine (NE) reuptake inhibitor that is used as an antidepressant. It has been shown to be a potent and selective NE reuptake inhibitor with a high affinity towards the NE transporter in rat brain synaptosomes, with potency several times higher than that of tricyclic antidepressants. Nisoxetine's major advantage over other antidepressants is its high efficiency, which makes it suitable for large-scale production. The synthesis of nisoxetine involves two steps: 1) reaction of 3-[methyl(phenylmethyl)amino]-1-phenyl-1-propanone hydrochloride with toluene to form the corresponding methyl ester and 2) hydrogenation of the methyl ester to form nisoxetine. This synthesis is efficient, stable, and chiral due to the use of bimetallic catalysts.</p>Fórmula:C17H19NO•HClPureza:Min. 95%Cor e Forma:PowderPeso molecular:289.8 g/molN-Desmethyl cyamemazine maleate
CAS:<p>Cyamemazine is an antipsychotic drug that has been used for the treatment of schizophrenia and other psychotic disorders. N-Desmethyl cyamemazine maleate, a metabolite of cyamemazine, has been shown to have neuroprotective effects in vitro.</p>Fórmula:C18H19N3S·C4H4O4Pureza:Min. 95%Peso molecular:425.5 g/mol2-Hydroxy-2-{4-[2-(hydroxyethoxy)ethyl]piperazin-1-yl}dithiazepin
CAS:<p>2-Hydroxy-2-{4-[2-(hydroxyethoxy)ethyl]piperazin-1-yl}dithiazepin (LPSE) is a monoclonal antibody that is used in the diagnosis of atrial fibrillation. It binds to the antigenic determinant on the surface of atrial cells and also has high affinity for cardiac troponin I. LPSE has biochemical properties that distinguish it from other antibodies and is not known to have any adverse reactions or interactions with other drugs. The clinical relevance of LPSE has been demonstrated by its ability to detect atrial cells in tissue samples from patients with atrial fibrillation, and to discriminate between samples taken from patients who had undergone catheter ablation or those who had not undergone this procedure. LPSE binds to tetroxide, gamma-aminobutyric acid (GABA), amides, and proteins, as well as hl-60 cells,</p>Fórmula:C21H27N3O3SPureza:Min. 97 Area-%Cor e Forma:Yellow Clear LiquidPeso molecular:401.53 g/molN-Cyano-N'-methyl-N''-[2-[(5-methyl-1H-imidazol-4-yl)methylsulphinyl]ethyl]guanidine
CAS:<p>N-Cyano-N'-methyl-N''-[2-[(5-methyl-1H-imidazol-4-yl)methylsulphinyl]ethyl]guanidine is an acetylcholinesterase inhibitor that is used to treat Alzheimer's disease. It has been shown to be safe and effective in clinical studies with a number of populations. The drug binds to the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine. This action prevents the breakdown of acetylcholine, leading to increased levels of this chemical in the brain and improved function. NCAEMG has also been found to increase uptake of drugs by proximal tubules in humans, which may be due to its ability to inhibit cimetidine metabolism.</p>Fórmula:C10H16N6OSPureza:Min. 95%Cor e Forma:White PowderPeso molecular:268.34 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole N-oxide
CAS:<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole N-oxide is an ammonium salt of a sulfoxide with a chloride. It is also known as esomeprazole magnesium. This drug is used in the preparation of pharmaceutical preparations and is used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and other conditions. The magnesium salt form is a polymorphic substance that has a crystalline form that occurs in nature, called alpha form, and a synthetic form that occurs in laboratory experiments and has been designated beta form. The alpha form exhibits enantioselectivity when it binds to the enzyme pepsin, which causes the drug to have an antiulcer effect.</p>Fórmula:C17H19N3O4SPureza:Min. 95%Cor e Forma:PowderPeso molecular:361.42 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole
CAS:<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole is an inhibitor of cytochrome P450 2C19. It has been shown to inhibit the activity of this enzyme in a concentration dependent manner and to enhance the activity of omeprazole by inhibiting its metabolism. 5-Methoxy-2-[(4-methoxy, 3,5 dimethylpyridiniumyl)methyl]sulfonyl]-1H benzimidazole is used as a model system for studying drug interactions due to its ability to inhibit cytochrome P450 2C19 and CYP2C19 protein expression. 5 METHOXY - 2 - [[ ( 4 - METHOXY - 3 , 5 - DIMETHYL - 2 - PYRIDINYL ) M</p>Fórmula:C17H19N3O4SPureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:361.42 g/molN,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine tartrate
CAS:<p>N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine tartrate (DMNPA) is a synthetic compound with the molecular formula C14H17NO. DMNPA is used as an analytical reference standard for the quantification of N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2thienyl) propanamine HCl by HPLC. DMNPA has been shown to be a metabolite of the drug product, where it is formed from oxidation of the parent drug.</p>Fórmula:C19H21NOS·C4H6O6Pureza:Min. 95%Peso molecular:461.53 g/molPitavastatin 3S,5R isomer calcium
CAS:<p>Pitavastatin 3S,5R isomer Calcium Salt is a potent inhibitor of cholesterol biosynthesis. It is marketed as the hemihydrate form under the trade name Pravacol and is used in the treatment of type 2 diabetes. Pitavastatin 3S,5R isomer Calcium Salt inhibits cholesterol biosynthesis by blocking HMG-CoA reductase, which converts 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) to mevalonate (MVA). The active metabolite, pitavastatin, binds to the regulatory region of HMG-CoA reductase and prevents it from converting MVA to HMG-CoA. This reduces the pool of HMG-CoA available for conversion to cholesterol. The inhibition of this enzyme slows down the production of cholesterol and decreases blood levels. It has been approved for use in adults with type 2 diabetes and for lowering high</p>Fórmula:(C25H24FNO4)2•CaPureza:Min. 95%Cor e Forma:White/Off-White SolidPeso molecular:880.98 g/molHomo sildenafil
CAS:<p>Analogue of sildenafil</p>Fórmula:C23H32N6O4SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:488.6 g/mol8-Fluoro-2,2-dimethyl-9-(4-methyl-1-piperazinyl)-6-oxo-2H,6H-oxazolo[5,4,3-ij]quinoline-5-carboxylic acid
CAS:<p>8-Fluoro-2,2-dimethyl-9-(4-methyl-1-piperazinyl)-6-oxo-2H,6H-oxazolo[5,4,3-ij]quinoline-5-carboxylic acid is a synthetic drug product. It has been shown to be metabolized by CYP3A4 and CYP3A5 into an impurity that is not detectable with HPLC. 8FQCA is also studied for its pharmacological effects on the metabolic pathways of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and cyclooxygenase 2 (COX2).</p>Fórmula:C18H20FN3O4Pureza:Min. 95%Peso molecular:361.37 g/mol4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinecarboxaldehyde
CAS:<p>4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinecarboxaldehyde is a synthetic chemical compound that has not been approved by the FDA. It is a metabolite of the drug product 4-(4-amino-6,7-dimethoxyquinazolin-2yl)-1-piperazinecarboxylic acid hydrochloride. The CAS number for this chemical is 102714-74-9. This product has been synthesized in our laboratory and is available for purchase at Custom Synthesis. This product can be used as an impurity standard for HPLC analysis or as a research and development chemical for drug development and pharmacopoeia purposes.</p>Fórmula:C15H19N5O3Pureza:Min. 95%Peso molecular:317.34 g/mol[[5-[[(2-Aminoethyl)thio]methyl]furan-2-yl]methyl]dimethylamine
CAS:<p>[[5-[[(2-Aminoethyl)thio]methyl]furan-2-yl]methyl]dimethylamine is a metabolite of the drug [[5-[[(2-Aminoethyl)thio]methyl]furan-2-yl]methyl]dimethylamine. It is found in the urine of patients taking [[5-[[(2-Aminoethyl)thio]methyl]furan-2-yl]methyl]dimethylamine and has been used as an impurity standard for [[5-[(2-(Aminoethyl)thio]-methyl]-furan-2ylmethyl]-dimethylamine.</p>Fórmula:C10H18N2OSPureza:Min. 95%Cor e Forma:Colorless Clear LiquidPeso molecular:214.33 g/molTafenoquine
CAS:<p>Tafenoquine (WR 238605) is an antimalarial prophylactic agent with schizonticidal activity, useful in hemolytic anemia research.</p>Fórmula:C24H28F3N3O3Pureza:99.56%Cor e Forma:SolidPeso molecular:463.49Varenicline
CAS:<p>Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.</p>Fórmula:C13H13N3Pureza:99.76%Cor e Forma:SolidPeso molecular:211.26Pitavastatin
CAS:<p>Pitavastatin (NK-104) is an HMG-CoA reductase inhibitor with hypocholesterolemic and neuroprotective activities.</p>Fórmula:C25H24FNO4Pureza:97.17%Cor e Forma:SolidPeso molecular:421.46Ropinirole
CAS:<p>Ropinirole, D2-like agonist, no D1 affinity, Ki 29 nM for D2, treats Parkinson's.</p>Fórmula:C16H24N2OPureza:99.68%Cor e Forma:SolidPeso molecular:260.383-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
CAS:Fórmula:C9H15BN2O2Pureza:97%Cor e Forma:SolidPeso molecular:194.04Methyl 6-bromo-2-oxo-1,2-dihydropyridine-3-carboxylate
CAS:Pureza:97%Cor e Forma:SolidPeso molecular:232.0330048quinoxaline-5-carbaldehyde
CAS:Fórmula:C9H6N2OPureza:98%Cor e Forma:Light brown powderPeso molecular:158.164-{[5-(Trifluoromethyl)-2-pyridinyl]oxy}aniline
CAS:Fórmula:C12H9F3N2OPureza:97%Cor e Forma:SolidPeso molecular:254.2125,5′-Bis(trifluoromethyl)-2,2′-bipyridine
CAS:Fórmula:C12H6F6N2Pureza:95%Cor e Forma:SolidPeso molecular:292.1846-BROMO-2-FLUORONICOTINIC ACID
CAS:Fórmula:C6H3BrFNO2Pureza:95%Cor e Forma:SolidPeso molecular:219.9972,4-Dibromo-5-nitropyridine
CAS:Fórmula:C5H2Br2N2O2Pureza:97%Cor e Forma:LiquidPeso molecular:281.891(S)-Methyl 2-(morpholin-3-yl)acetate hydrochloride
CAS:Fórmula:C7H14ClNO3Pureza:98%Peso molecular:195.64(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(thiophen-3-yl)propanoic acid
CAS:Fórmula:C22H19NO4SPureza:95%Peso molecular:393.461-Isopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
CAS:Fórmula:C12H21BN2O2Pureza:95%Cor e Forma:SolidPeso molecular:236.126-Chloroquinazoline-2,4(1H,3H)-dione
CAS:Fórmula:C8H5ClN2O2Pureza:96%Cor e Forma:SolidPeso molecular:196.594-(2,6-Dichloropyrimidin-4-yl)morpholine
CAS:Fórmula:C8H9Cl2N3OPureza:97%Cor e Forma:SolidPeso molecular:234.086-(Difluoromethoxy)pyridin-3-amine
CAS:Fórmula:C6H6F2N2OPureza:95%Cor e Forma:LiquidPeso molecular:160.1241-Pyridin-4-ylmethanamine
CAS:Fórmula:C6H8N2Pureza:97%Cor e Forma:Liquid, ClearPeso molecular:108.1444-Bromo-5-methylpyridin-2-amine
CAS:Fórmula:C6H7BrN2Pureza:98%Cor e Forma:Solid, No data available.Peso molecular:187.041-Hydroxy-6-oxo-1,6-dihydropyridine-2-carboxylic acid
CAS:Fórmula:C6H5NO4Pureza:98%Cor e Forma:Solid, White powderPeso molecular:155.109(5-Methyl-1H-pyrazol-3-yl)boronic acid
CAS:Fórmula:C4H7BN2O2Pureza:95%Cor e Forma:Solid, White powderPeso molecular:125.921,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one
CAS:Fórmula:C13H20BNO3Pureza:97%Cor e Forma:SolidPeso molecular:249.121,3-DIMETHYLPYRAZOLE-4-BORONIC ACID
CAS:Fórmula:C5H9BN2O2Pureza:95%Cor e Forma:SolidPeso molecular:139.95ethyl 3-nitro-1H-pyrazole-4-carboxylate
Fórmula:C6H7N3O4Pureza:97%Cor e Forma:Liquid, No data available.Peso molecular:185.1391-(6-(Dimethylamino)pyridin-3-yl)-2,2,2-trifluoroethan-1-one
CAS:Pureza:97%Peso molecular:218.1790009Ref: 10-F712137
1g888,00€5g2.352,00€10g3.476,00€2.5g1.658,00€50mg188,00€100mg285,00€250mg481,00€500mg723,00€Methyl 1-ethyl-4-nitro-1H-pyrazole-5-carboxylate
CAS:Fórmula:C7H9N3O4Pureza:97%Peso molecular:199.1664-(Tert-butyl)-5-(hydroxymethyl)-1,2-dihydro-3H-pyrazol-3-one
CAS:Pureza:96%Peso molecular:170.2120056METHYL 4-CHLORO-5-METHOXYPICOLINATE
CAS:Fórmula:C8H8ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:201.612-Oxo-6-(trifluoromethyl)-1,2-dihydropyridine-4-carboxylic acid
CAS:Pureza:97%Cor e Forma:SolidPeso molecular:207.1080017(1-Methyl-1H-pyrazol-4-yl)methanamine dihydrochloride
CAS:Fórmula:C5H11Cl2N3Pureza:97%Peso molecular:184.061-Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile
CAS:Fórmula:C7H6N2OPureza:98%Peso molecular:134.1381,3,5-TRIS(2-HYDROXYETHYL)CYANURIC ACID
CAS:Fórmula:C9H15N3O6Pureza:95%Cor e Forma:SolidPeso molecular:261.2343,6-Difluoropyridin-2-amine
CAS:Fórmula:C5H4F2N2Pureza:95%Cor e Forma:Solid, No data available.Peso molecular:130.098trans-4-[4-[6-(Aminocarbonyl)-3,5-dimethyl-2-pyrazinyl]phenyl]cyclohexaneacetic acid methyl ester
CAS:Pureza:98%Peso molecular:381.4761-Methyl-3,5-dinitropyridin-2(1H)-one
CAS:Fórmula:C6H5N3O5Pureza:96%Cor e Forma:SolidPeso molecular:199.1225-Fluoro-2-(trifluoromethyl)pyridine
CAS:Fórmula:C6H3F4NPureza:98%Cor e Forma:LiquidPeso molecular:165.0912-Chloro-4-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
CAS:Pureza:96%Peso molecular:257.51-(Cyclopropylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
CAS:Fórmula:C13H21BN2O2Pureza:97%Cor e Forma:SolidPeso molecular:248.13
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