Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65924 produtos de "Derivados de Quinazolina e Quinolina"
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2-CHLORO-6-(TRIFLUOROMETHYL)PYRIDINE-4-CARBOXAMIDE
CAS:Fórmula:C7H4ClF3N2OPureza:95.0%Peso molecular:224.572-(MORPHOLINOMETHYL)THIOPHEN-4-BORONIC ACID, PINACOL ESTER
CAS:Fórmula:C15H24BNO3SPureza:98%Cor e Forma:SolidPeso molecular:309.23(5-BROMO-2-METHOXYPYRIDIN-3-YL)BORONIC ACID
CAS:Fórmula:C6H7BBrNO3Pureza:≥95%Cor e Forma:Liquid, No data available.Peso molecular:231.844-Amino-1-(1-Boc-azetidin-3-yl)-1H-pyrazole
CAS:Fórmula:C11H18N4O2Pureza:95%Cor e Forma:LiquidPeso molecular:238.291TERT-BUTYL (R)-(1-(3-BROMOPYRIDIN-2-YL)ETHYL)CARBAMATE
CAS:Fórmula:C12H17BrN2O2Pureza:95.0%Peso molecular:301.1842-Chloro-3-(4-ethoxycarbonylbenzoyl)pyridine
CAS:Fórmula:C15H12ClNO3Pureza:97.0%Peso molecular:289.722-(5-Methylpyridin-2-yl)acetic acid
CAS:Fórmula:C8H9NO2Pureza:97%Cor e Forma:SolidPeso molecular:151.1654-Methyl-1-(oxan-4-ylmethyl)-1H-pyrazol-5-amine
CAS:Fórmula:C10H17N3OPureza:>95%Peso molecular:195.266ethyl 3-{[3-(morpholin-4-yl)propyl]amino}propanoate
CAS:Fórmula:C12H24N2O3Pureza:95.0%Peso molecular:244.3353-(2-Chloroethyl)quinazoline-2,4(1H,3H)-dione
CAS:Fórmula:C10H9ClN2O2Pureza:97%Cor e Forma:Liquid, No data available.Peso molecular:224.643-(3-(Dimethoxymethyl)-1H-pyrazol-5-yl)pyridine
CAS:Fórmula:C11H13N3O2Pureza:97%Peso molecular:219.2441-(5-Methylpyridin-2-yl)ethanamine dihydrochloride
CAS:Fórmula:C8H14Cl2N2Pureza:95.0%Peso molecular:209.118-Hydroxy-7-iodoquinoline-5-sulfonic acid
CAS:Fórmula:C9H6INO4SPureza:95%Cor e Forma:SolidPeso molecular:351.113,5-Dimethylmorpholine hydrochloride
CAS:Fórmula:C6H14ClNOPureza:≥97%Cor e Forma:Solid, Off-white powderPeso molecular:151.633-Chloro-4-(isopropylsulphonyl)-5-(methylthio)-thiophene-2-carboxylic acid
CAS:Fórmula:C9H11ClO4S3Peso molecular:314.815-(1,3-Dioxolan-2-yl)-2-thienyl undecyl ketone
CAS:Fórmula:C19H30O3SPureza:97.0%Peso molecular:338.511-(5-Bromo-2-fluoropyridin-3-yl)ethanone
CAS:Fórmula:C7H5BrFNOPureza:98%Cor e Forma:SolidPeso molecular:218.0252-(1-piperidinyl)-8-quinolinol
CAS:Fórmula:C14H16N2OPureza:95.0%Cor e Forma:SolidPeso molecular:228.2956-Chloro-2-(difluoromethyl)-3-fluoropyridine
CAS:Fórmula:C6H3ClF3NPureza:98%Cor e Forma:SolidPeso molecular:181.54(2-(1H-Pyrazol-1-yl)phenyl)methanamine hydrochloride
CAS:Fórmula:C10H12ClN3Pureza:95%Cor e Forma:SolidPeso molecular:209.681-Methyl-5-nitro-6-oxo-1,6-dihydropyridine-3-carboxylic acid
CAS:Fórmula:C7H6N2O5Pureza:95.0%Peso molecular:198.1341-(4-Methyl-benzyl)-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
CAS:Pureza:95%Peso molecular:298.1900024[4-(4-fluorophenyl)-1H-pyrazol-1-yl]acetic acid
CAS:Fórmula:C11H9FN2O2Pureza:95%Peso molecular:220.203(R)-2-Amino-2-(6-chloropyridin-3-yl)ethanol dihydrochloride
CAS:Fórmula:C7H11Cl3N2OPureza:97.0%Peso molecular:245.535-Fluoro-4,7-bis(5-(trimethylstannyl)thiophen-2-yl)benzo[c][1,2,5]thiadiazole
CAS:Pureza:99%(LC-MS);RGPeso molecular:644.02001955-Hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid
CAS:Fórmula:C6H5NO4Pureza:95%Peso molecular:155.1091-(3-Chloro-5-trifluoromethyl)-2-pyridyl-4-piperidinecarboxamide
CAS:Fórmula:C12H13ClF3N3OPureza:97%Peso molecular:307.72-[2-(Aminomethyl)pyridin-4-yl]-1,2- thiazinane-1,1-dione dihydrochloride
Fórmula:C10H17Cl2N3O2SPeso molecular:314.233-Chloro-5-(trifluoromethyl)pyridine-2-carboxylate acid
CAS:Fórmula:C7H3ClF3NO2Pureza:97%Cor e Forma:SolidPeso molecular:225.555-Ethoxy-1-methyl-1H-pyrazole-4-carboxylic acid
CAS:Fórmula:C7H10N2O3Pureza:97%Peso molecular:170.168(R)-tert-Butyl 3-(3-aminopyridin-2-yloxy)pyrrolidine-1-carboxylate
CAS:Fórmula:C14H21N3O3Pureza:95.0%Peso molecular:279.343-(1,1-Dimethylethyl)-1-[(4-fluorophenyl)methyl]-1H-pyrazole-5-carboxylic acid hydrazide
CAS:Cor e Forma:SolidPeso molecular:290.15Icotinib
CAS:Icotinib (Conmana) is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity.Fórmula:C22H21N3O4Pureza:99.76% - 99.94%Cor e Forma:SolidPeso molecular:391.42Diphenidol
CAS:<p>Diphenidol, a muscarinic antagonist, is employed as an antivertigo and antiemetic agent.</p>Fórmula:C21H27NOCor e Forma:Needles From Petroleum Ether SolidPeso molecular:309.45Meclofenamic acid
CAS:Meclofenamic acid: non-selective gap-junction blocker, FTO inhibitor, anti-inflammatory.Fórmula:C14H11Cl2NO2Pureza:99.98%Cor e Forma:SolidPeso molecular:296.15Penbutolol sulfate
CAS:<p>Penbutolol sulfate ((-)-Terbuclomine) is able to bind to both β2-adrenergic receptor and β1-adrenergic receptor, thus making it a non-selective β blocker.</p>Fórmula:C18H29NO2H2O4SPureza:98.55%Cor e Forma:SolidPeso molecular:340.47Prothioconazole
CAS:Prothioconazole (Proline 480 SC Fungicide) is a chiral triazole fungicide in plant pathogen control.Fórmula:C14H15Cl2N3OSPureza:99.77%Cor e Forma:Un3077 9/Pg 3Peso molecular:344.26Esmolol hydrochloride
CAS:Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension.Fórmula:C16H25NO4·HClPureza:98.72% - 99.48%Cor e Forma:White SolidPeso molecular:331.15(3S,4S)-Tofacitinib
CAS:<p>(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.</p>Fórmula:C16H20N6OPureza:98%Cor e Forma:SolidPeso molecular:312.37Procymidone
CAS:Procymidone is a broad-spectrum fungicide that inhibits fungal glycerol triester synthesis, thereby disrupting hyphal growth. androgen receptor (AR) antagonistFórmula:C13H11Cl2NO2Pureza:99.86%Cor e Forma:Colorless SolidPeso molecular:284.14Betrixaban
CAS:Betrixaban is a non-VKORC1 anticoagulant targeting factor Xa, with low hERG affinity, used to prevent VTE in adults with mobility issues.Fórmula:C23H22ClN5O3Pureza:99.33%Cor e Forma:SolidPeso molecular:451.91Itopride free base
CAS:<p>Itopride HCl combats dyspepsia and GERD, inhibiting AChE and blocking D2 receptors.</p>Fórmula:C20H26N2O4Cor e Forma:WhitePeso molecular:358.43Pardoprunox
CAS:Pardoprunox (SLV-308) is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.Fórmula:C12H15N3O2Pureza:98%Cor e Forma:SolidPeso molecular:233.27Ticlopidine
CAS:Ticlopidine (PCR 5332) is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor.Fórmula:C14H14ClNSPureza:99.67%Cor e Forma:SolidPeso molecular:263.79Amfenac
CAS:Amfenac promotes apoptosis in ARPE-19 cell culture.Fórmula:C15H13NO3Cor e Forma:SolidPeso molecular:255.27Mephenoxalone
CAS:Mephenoxalone is a muscle relaxant and mild anxiolytic. It inhibits neuron transmission and relaxing skeletal muscles by inhibiting the reflex arc.Fórmula:C11H13NO4Pureza:98%Cor e Forma:SolidPeso molecular:223.23Bicalutamide Sulfoxide
CAS:Produto Controlado<p>Impurity Bicalutamide USP Related Compound A<br>Applications Bicalutamide Sulfoxide is a derivative of Bicalutamide (B382000), non-steroidal peripherally active antiandrogen. Used as an antiandrogen, antineoplastic (hormonal).<br>References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),<br></p>Fórmula:C18H14F4N2O3SCor e Forma:NeatPeso molecular:414.376-Oxo-(S,S)-Palonosetron (~90%)
CAS:Produto Controlado<p>Applications 6-Oxo-(S,S)-Palonosetron is an impurity of (S,S)-Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.<br>References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),<br></p>Fórmula:C19H22N2O2Pureza:~90%Cor e Forma:NeatPeso molecular:310.395-Dehydro Tolvaptan
CAS:Produto Controlado<p>Applications 5-Dehydro Tolvaptan is an impurity of Tolvaptan (T536650), a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH g<br>References Yin, L., et al.: Tetrahedron, Asym., 21, 2390 (2010); Torisawa, Y., et al.: Bioorg. Med. Chem. Lett., 17, 6455 (2007); Kondo, K., et al.: Bioorg. Med. Chem., 7, 1743 (1999);<br></p>Fórmula:C26H23ClN2O3Cor e Forma:NeatPeso molecular:446.934'-Desmorpholino 4'-[N-(5-chloro-2-carboxy-thienyl)N-(5-Carboxy-3-oxa-pentyl)]amino Rivaroxaban
CAS:Produto ControladoFórmula:C25H24Cl2N4O6S2Cor e Forma:NeatPeso molecular:611.52Fimasartan
CAS:Produto Controlado<p>Applications Fimasartan is a new angiotensin II receptor blocker antagonist and also functions as an antihypertensive agent.<br>References Lee, H., et al.: Drugs, 76, 1015 (2016)<br></p>Fórmula:C27H31N7OSCor e Forma:NeatPeso molecular:501.65Dipyridamole Tripiperidine
CAS:Produto Controlado<p>Impurity Dipyridamole EP Impurity A<br>Applications Dipyridamole Tripiperidine (Dipyridamole EP Impurity A) is a Dipyridamole (D492625) impurity.<br>References Bakken, G.A., et al.: J. Med. Chem., 43, 4534 (2000),<br></p>Fórmula:C25H40N8O2Cor e Forma:NeatPeso molecular:484.644-(5-Chloro-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-1-formylpiperidine
CAS:Produto Controlado<p>Impurity Buspirone EP Impurity B<br>Applications An impurity of the gastrokinetic and antinauseant drug Domperidone (D531100).<br></p>Fórmula:C13H14ClN3O2Cor e Forma:BeigePeso molecular:279.72N-[1-(4-Chlorophenyl)cyclobutylmethyl]-N,N-dimethylamine Hydrochloride
CAS:Produto Controlado<p>Applications N-[1-(4-Chlorophenyl)cyclobutylmethyl]-N,N-dimethylamine Hydrochloride is an impurity of Sibutramine Hydrochloride (S422500), a serotonin and noradrenaline reuptake inhibitor.<br>References Hanotin, C., et al.: Int. J. Obesity, 22, 32 (1998)<br></p>Fórmula:C13H19Cl2NCor e Forma:NeatPeso molecular:260.24-Desfluoro-2-Fluoro Droperidol
CAS:<p>Applications 4-Desfluoro-2-Fluoro Droperidol is an impurity of Droperidol (D679500), a D1, D2 dopamine receptor antagonist; butyrophenone antipsychotic and anti-emetic.<br>References Yelnosky, J., et al.: Toxicol. Appl. Pharmacol., 6, 37 (1964), Janicki, C.A., et al.: Anal. Profiles Drug Subs., 7, 171 (1978), Hamik, et al.: Cancer Chemother. Pharmacol., 24, 307 (1989), Heyer, E.J., et al.: Brain Res., 863, 20 (2000),<br></p>Fórmula:C22H22FN3O2Cor e Forma:NeatPeso molecular:379.4274Benzoin
CAS:Produto Controlado<p>Applications Benzoin has been used as a catalyst in photoinitiation.<br>References Voll, D., et. al.: Macromolecules, 44, 2542 (2011)<br></p>Fórmula:C14H12O2Cor e Forma:Off-WhitePeso molecular:212.24Methyl 5,6,7,8-Tetradehydro Risperidone
CAS:Produto Controlado<p>Applications An internal standard for Risperidone (R525000).<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>Fórmula:C24H25FN4O2Cor e Forma:White To Off WhitePeso molecular:420.482-Fluoro-4-desfluoro Bicalutamide
CAS:Produto Controlado<p>Impurity Bicalutamide EP Impurity B<br>Applications Bicalutamide impurity. Bicalutamide derivative.<br>References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988),<br></p>Fórmula:C18H14F4N2O4SCor e Forma:NeatPeso molecular:430.3734N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide
CAS:Produto Controlado<p>Applications N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide was used in the study to discover a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth. N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide is an impurity of Intedanib (I666650), which is an antitumor agent.<br>References Edupuganti, R., et al.: Bioorg. Med. Chem., 25, 2609 (2017); Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>Fórmula:C29H31N5O2Cor e Forma:NeatPeso molecular:481.59rac Methotrimeprazine Sulfoxide
CAS:Produto Controlado<p>Applications A metabolite of Methotrimeprazine (M260785).<br>References Haddad, P., et al.: Drugs, 62, 1649 (2002),<br></p>Fórmula:C19H24N2O2SCor e Forma:NeatPeso molecular:344.47N-Nitrosopendimethalin-d4
Produto ControladoFórmula:C13H14D4N4O5Cor e Forma:NeatPeso molecular:337.367
![ethyl 3-{[3-(morpholin-4-yl)propyl]amino}propanoate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF522758.webp&w=3840&q=75)
![1-(4-Methyl-benzyl)-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF696871.webp&w=3840&q=75)
![[4-(4-fluorophenyl)-1H-pyrazol-1-yl]acetic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF495982.webp&w=3840&q=75)
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![2-[2-(Aminomethyl)pyridin-4-yl]-1,2- thiazinane-1,1-dione dihydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF549959.webp&w=3840&q=75)
![3-(1,1-Dimethylethyl)-1-[(4-fluorophenyl)methyl]-1H-pyrazole-5-carboxylic acid hydrazide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF551208.webp&w=3840&q=75)
![4'-Desmorpholino 4'-[N-(5-chloro-2-carboxy-thienyl)N-(5-Carboxy-3-oxa-pentyl)]amino Rivaroxaban](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD296820.webp&w=3840&q=75)
![N-[1-(4-Chlorophenyl)cyclobutylmethyl]-N,N-dimethylamine Hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC378585.webp&w=3840&q=75)
![N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperaz…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD452513.webp&w=3840&q=75)
