Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65630 produtos de "Derivados de Quinazolina e Quinolina"
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Empagliflozin S-furanose
CAS:<p>Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.</p>Fórmula:C23H27ClO7Pureza:Min. 95%Cor e Forma:PowderPeso molecular:450.91 g/molN-De[2-(methylsulfonyl)ethyl] lapatinib
CAS:<p>Lapatinib is a tyrosine kinase inhibitor that blocks the epidermal growth factor receptor (EGFR) and other tyrosine kinases. It is used in cancer treatment to inhibit tumor growth, with a high success rate. Lapatinib is also used to treat lung cancer and other types of cancer. The drug has been shown to inhibit EGFR phosphorylation in vitro, which leads to inhibition of cell proliferation and induction of apoptosis. Lapatinib also inhibits the expression of EGFR downstream target genes such as b-raf, serine/threonine-protein kinase, and cyp3a5.</p>Fórmula:C26H20ClFN4O2Pureza:Min. 95%Peso molecular:474.91 g/molPitavastatin N-oxide
CAS:<p>Pitavastatin N-oxide is a drug product that is an analytical standard and natural API impurity. It is used in the synthesis of other drugs, such as pitavastatin, which is a statin drug used to lower cholesterol levels. Pitavastatin N-oxide has been shown to be a potent inhibitor of HMG-CoA reductase, the enzyme that catalyzes the conversion of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) to mevalonate. This inhibits cholesterol production and lowers levels of low density lipoprotein (LDL) cholesterol in the blood.</p>Fórmula:C25H24FNO5Pureza:Min. 95%Peso molecular:437.46 g/molEzetimibe ketone
CAS:<p>Ezetimibe ketone is a lipid-lowering agent that inhibits cholesterol absorption through the inhibition of Niemann-Pick C1-like 1 (NPC1L1). Ezetimibe ketone is used to reduce the levels of low-density lipoprotein cholesterol (LDL-C) in patients with primary hypercholesterolemia, sitosterolemia, and familial combined hyperlipidemia. Ezetimibe ketone has been shown to be bioequivalent to ezetimibe, which is an oral drug that inhibits cholesterol absorption by blocking NPC1L1. The drug binds to the NPC1L1 receptor in the brush border membrane of enterocytes and prevents cholesterol uptake. Ezetimibe ketone has a high solubility in organic solvents such as dichloromethane or chloroform. It also has a high melting point, which makes it suitable for use on chromatographic columns.</p>Fórmula:C24H19F2NO3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:407.41 g/molVildagliptin related compound F
CAS:<p>Vildagliptin related compound F (VRCF) is a drug product that has been custom synthesized. VRCF is a high purity, analytical standard. It is metabolized in the body and can be used as a research and development standard to study the metabolism of vildagliptin. VRCF is a natural metabolite that has been identified as an impurity in the drug product Vildagliptin. VRCF has not been recognized by the USP or EP for use as an impurity standard. CAS no: 1789703-36-1</p>Fórmula:C17H24N2O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:304.4 g/molEcopipam
CAS:<p>Ecopipam: orally active, selective dopamine D1/D5 antagonist (Ki: 1.2 nM/2.0 nM). 40x more selective over D2/D4/5-HT/α2a. For schizophrenia, obesity research.</p>Fórmula:C19H20ClNOPureza:99.68%Cor e Forma:SolidPeso molecular:313.82Edoxaban
CAS:<p>Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.</p>Fórmula:C24H30ClN7O4SPureza:97.67% - 99.71%Cor e Forma:SolidPeso molecular:548.06Imipramine
CAS:<p>Imipramine (Dimipressin) is a Fascin1 inhibitor with antitumor activity and induces apoptosis.</p>Fórmula:C19H24N2Pureza:99.4%Cor e Forma:White To Off-White /Hydrochloride/ SolidPeso molecular:280.413-Trifluoroacetylamino linagliptin
CAS:<p>Please enquire for more information about 3-Trifluoroacetylamino linagliptin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C27H27F3N8O3Pureza:Min. 95%Peso molecular:568.55 g/mol(Z)-Thiothixene
CAS:<p>(Z)-Thiothixene (Thiothixene) is an antagonist of serotonergic receptor.</p>Fórmula:C23H29N3O2S2Pureza:99.21%Cor e Forma:Yellow To Yellow With A Tan Cast PowderPeso molecular:443.63Eltenac
CAS:<p>Eltenac, a cyclooxygenase (COX) inhibitor, is used potentially for the treatment of pain.</p>Fórmula:C12H9Cl2NO2SPureza:98.53%Cor e Forma:SolidPeso molecular:302.18UNC0321
CAS:<p>UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.</p>Fórmula:C27H45N7O3Pureza:99.80%Cor e Forma:SolidPeso molecular:515.69Roflumilast Impurity A
CAS:<p>Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.</p>Fórmula:C16H14Cl2N2O3Pureza:Min. 95%Peso molecular:353.2 g/mol2,3,4,5-Tetradehydro alfuzosin hydrochloride
CAS:<p>Alfuzosin is a potent, selective, and long-acting α1A-adrenergic receptor antagonist. It is used to treat benign prostatic hyperplasia (BPH) in males. Alfuzosin is also used as an antihypertensive agent, for the treatment of pheochromocytoma, and for the treatment of benign prostatic hyperplasia in males. The hydrogenation of 2,3,4,5-tetradehydroalfuzosin to alfuzosin hydrochloride is performed by liquid hydrogenation or by hydrogenation on a palladium catalyst in a mixture of dimethylformamide and hexamethylphosphoramide. This process minimizes the formation of impurities such as 2,3,4-trimethoxy alfuzosin.</p>Fórmula:C19H24ClN5O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:421.88 g/molDesfluoro ezetimibe
CAS:<p>Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.</p>Fórmula:C24H22FNO3Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:391.43 g/molSovaprevir
CAS:<p>Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.</p>Fórmula:C43H53N5O8SPureza:99.11%Cor e Forma:SolidPeso molecular:799.97Brivaracetam CV
CAS:Produto ControladoLactams, nesoiFórmula:C11H20N2O2Cor e Forma:White Off-White SolidPeso molecular:212.15248Givinostat hydrochloride
CAS:<p>Givinostat HCl (ITF2357 HCl) inhibits HDAC1/3 (IC50: 198/157 nM) with anti-inflammatory, anti-angiogenic, and antineoplastic properties.</p>Fórmula:C24H28ClN3O4Pureza:99.39%Cor e Forma:SolidPeso molecular:457.95Amlodipine EP Impurity F maleate
CAS:<p>Amlodipine EP Impurity F maleate is an impurity of amlodipine, a drug product. It is a natural substance that has been classified as an API impurity in the United States Pharmacopeia (USP). The chemical name for this drug is 3-(2-chlorophenyl)-1-methyl-5-(o-tolyloxy)-2,4-dihydro-6H-[1,3]thiazolo[3,2-a]pyrimidin-7-one. Amlodipine EP Impurity F maleate has the following properties: C12H9ClNO2S and a melting point of 210°C with a purity of 99.5%. This compound was synthesized by custom synthesis and is used as an analytical standard for HPLC. This compound was also used during the development of amlodipine to determine its metabolism studies.</p>Fórmula:C19H23ClN2O5•C4H4O4Pureza:Min. 95%Peso molecular:510.92 g/molPantoprazole sulphide
CAS:<p>Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.</p>Fórmula:C16H15F2N3O3SPureza:Min. 95%Cor e Forma:PowderPeso molecular:367.37 g/molAGPS-IN-2i
CAS:AGPS-IN-2i inhibits alkylglycerol phosphate synthase, affecting ether lipid metabolism and reducing cancer cell migration and proliferation.Fórmula:C18H17F2N3O2Pureza:98.92%Cor e Forma:SolidPeso molecular:345.34ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS:<p>Please enquire for more information about ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C22H22N4O4Pureza:Min. 95%Peso molecular:406.43 g/molN-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
CAS:<p>N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide (NUOX) is a potential anticancer agent that has been shown to have an acidic pKa of 5.8 and to be active against cancer cells in the same way as bicalutamide, which is a known antiandrogen. NUOX has been shown to increase the number of cavities in polybenzimidazole (PBI) films by enhancing the rate of oxidation. NUOX also inhibits the growth of human cancer cells by binding sulfide groups on proteins and DNA, inhibiting cellular respiration. NUOX is not water soluble, so it must be dissolved in solvents such as acetonitrile or chloroform before administration.</p>Fórmula:C12H9F3N2O2Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:270.21 g/molLaduviglusib trihydrochloride
CAS:<p>Laduviglusib trihydrochloride, a GSK-3α/β inhibitor (IC50: 10/6.7 nM), activates Wnt/β-catenin signaling and induces autophagy.</p>Fórmula:C22H20Cl5N8Pureza:99.34%Cor e Forma:SolidPeso molecular:573.71Pitolisant
CAS:<p>Pitolisant is a potent and selective nonimidazole inverse agonist that acts on the recombinant human histamine H3 receptor with Ki of 0.16 nM.</p>Fórmula:C17H26ClNOPureza:99.84%Cor e Forma:SolidPeso molecular:295.851-Fluoronaphthalene
CAS:<p>1-Fluoronaphthalene is a polyunsaturated compound that is used in analytical chemistry for the determination of test samples. It is an inhibitor of the enzyme IDO1, which plays an important role in the regulation of immune function, and has been shown to have anti-inflammatory properties. 1-Fluoronaphthalene can be synthesized by reacting n-dimethyl formamide with hydrogen fluoride and then adding a diazonium salt and hydrochloric acid. The UV absorption spectrum of 1-fluoronaphthalene displays a maximum at 248 nm. This compound binds to cation channels on cells, causing hyperpolarization.</p>Fórmula:C10H7FPureza:Min. 95%Peso molecular:146.16 g/molDB04760
CAS:<p>DB04760: selective MMP-13 inhibitor, non-zinc-chelating, IC50=8nM, reduces paclitaxel neurotoxicity, anticancer.</p>Fórmula:C22H20F2N4O2Pureza:99.93% - 99.99%Cor e Forma:SolidPeso molecular:410.42MMP-2/MMP-9 Inhibitor I
CAS:<p>MMP-2/MMP-9-IN-1: oral IV collagenase inhibitor; IC50: 0.24 μM (MMP-9), 0.31 μM (MMP-2); targets cancer.</p>Fórmula:C21H19NO4SPureza:99.74%Cor e Forma:SolidPeso molecular:381.44CP-544439
CAS:<p>CP-544439 is an inhibitor of matrix metalloproteinase-13, which has an effect on adipose tissue development.</p>Fórmula:C18H19FN2O6SPureza:95.02% - 98.66%Cor e Forma:SolidPeso molecular:410.42(R)-Zanubrutinib
CAS:<p>(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).</p>Fórmula:C27H29N5O3Pureza:99.55%Cor e Forma:SolidPeso molecular:471.55Gallopamil
CAS:<p>Gallopamil blocks acid secretion (IC50: 10.9 μM), acts as antiarrhythmic, vasodilator, and is a methoxy Verapamil derivative.</p>Fórmula:C28H40N2O5Pureza:99.85%Cor e Forma:SolidPeso molecular:484.63Moveltipril
CAS:<p>Moveltipril (Moveltipril calcium) is a potent angiotensin-converting enzyme (ACE) inhibitor.Moveltipril is converted to captopril in the body for action.</p>Fórmula:C19H30N2O5SPureza:97.55% - 98.28%Cor e Forma:SolidPeso molecular:398.52Vildagliptin carboxylic acid methyl ester
CAS:<p>Please enquire for more information about Vildagliptin carboxylic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C18H28N2O4Pureza:Min. 95%Peso molecular:336.43 g/molArimoclomol
CAS:<p>Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (</p>Fórmula:C14H20ClN3O3Pureza:99.15%Cor e Forma:SolidPeso molecular:313.78Stepronin
CAS:<p>Stepronin (TTPG) shows expectorant activities and inhibits airway secretion.</p>Fórmula:C10H11NO4S2Pureza:99.59%Cor e Forma:White Or Off White CrystallinePeso molecular:273.33Ritodrine
CAS:<p>Ritodrine (DU21220) is a β-adrenergic agonist as well as an effective uterine relaxant that can be used in arrest premature labor research[1] [2].</p>Fórmula:C17H21NO3Cor e Forma:SolidPeso molecular:287.35Yonkenafil
CAS:<p>Yonkenafil, a PDE5 inhibitor, may reduce stroke damage and aid in Alzheimer's treatment.</p>Fórmula:C24H33N5O4SCor e Forma:SolidPeso molecular:487.61Apratastat
CAS:<p>Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs)</p>Fórmula:C17H22N2O6S2Pureza:98%Cor e Forma:SolidPeso molecular:414.5LY52
CAS:<p>LY52 is a matrix metalloproteinase-2 inhibitor. It acts by suppressing tumor invasion and metastasis.</p>Fórmula:C22H24N4O6Pureza:98%Cor e Forma:SolidPeso molecular:440.45ONO 4817
CAS:ONO-4817 suppresses MMPs, limiting plaque progression and aortic hyperplasia in hyperlipidemic rabbits.Fórmula:C22H28N2O6Cor e Forma:SolidPeso molecular:416.47XL-784
CAS:<p>XL-784 is a selective MMP inhibitor with low IC50s for MMP-1,2,3,8,9,13, modulating extracellular matrix remodeling, tumor invasion, and metastasis in cancer.</p>Fórmula:C42H42Cl2F4MgN6O16S2Pureza:98%Cor e Forma:SolidPeso molecular:1122.15Tianagliflozin
CAS:<p>Tianagliflozin, a sodium/glucose cotransporter 2 (SGLT-2) inhibitor, is used potentially for the treatment of type 2 diabetes.</p>Fórmula:C21H25ClO5Pureza:98%Cor e Forma:SolidPeso molecular:392.87Cobimetinib racemate
CAS:<p>Cobimetinib racemate (Cobimetinib (racemate)) (GDC-0973 racemate) is a selective inhibitor of MEK.Cobimetinib racemate is also known as a mitogen-activated</p>Fórmula:C21H21F3IN3O2Pureza:98.00% - 99.71%Cor e Forma:SolidPeso molecular:531.31MMP-145
CAS:<p>MMP-145 is used as a protease inhibitor.</p>Fórmula:C20H20N2O7SPureza:98%Cor e Forma:SolidPeso molecular:432.45Brilaroxazine
CAS:<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Fórmula:C22H25Cl2N3O3Pureza:99.36%Cor e Forma:SolidPeso molecular:450.36AZD-1656
CAS:<p>AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2</p>Fórmula:C24H26N6O5Pureza:97.07% - 99.37%Cor e Forma:SolidPeso molecular:478.5ROCK2-IN-7
CAS:<p>ROCK2 inhibitor is a chemical compound associated with the therapeutic management of psoriasis.</p>Fórmula:C26H28FN5OPureza:98%Cor e Forma:SolidPeso molecular:445.53Bufuralol
CAS:<p>Bufuralol (Ro 3-4787) is a 尾-adrenergic receptor blocker with a certain degree of sympathomimetic effects and can be used to study cardiovascular diseases.</p>Fórmula:C16H23NO2Pureza:98.26%Cor e Forma:SolidPeso molecular:261.36Levocabastine
CAS:<p>Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.</p>Fórmula:C26H29FN2O2Cor e Forma:SolidPeso molecular:420.52Z-PDLDA-NHOH
CAS:<p>Z-PDLDA-NHOH is a potent, specific vertebrate collagenase inhibitor [1].</p>Fórmula:C22H32N4O6Cor e Forma:SolidPeso molecular:448.51IK-862
CAS:<p>IK-862 is a selective TACE inhibitor with potential anti-inflammatory and anticancer activity for the study of neuritis.</p>Fórmula:C25H27N3O4Pureza:97.75% - 98.29%Cor e Forma:SolidPeso molecular:433.5Brasofensine
CAS:<p>Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.</p>Fórmula:C16H20Cl2N2OCor e Forma:SolidPeso molecular:327.25Mefenidil
CAS:<p>Mefenidil (McN-2378), a selective cerebral vasodilator, was shown to increase CBF in healthy brains without stimulating O2 uptake in a dog anesthesia model.</p>Fórmula:C12H11N3Pureza:98.27%Cor e Forma:SolidPeso molecular:197.24Saredutant
CAS:<p>Saredutant (SR 48968) is a selective neurokinin-2 (NK2) receptor antagonist that inhibits neurokinin A by blocking NK2 receptor, antidepressant and anxiolytic.</p>Fórmula:C31H35Cl2N3O2Pureza:99.12%Cor e Forma:SolidPeso molecular:552.54XL-784 free base
CAS:<p>XL-784 free base selectively inhibits MMPs with IC50: MMP-1 (1.9µM), MMP-2 (0.81nM), MMP-3 (120nM), MMP-8 (10.8nM), MMP-9 (18nM), MMP-13 (0.56nM).</p>Fórmula:C21H22ClF2N3O8SPureza:98%Cor e Forma:SolidPeso molecular:549.93Fluvalinate
CAS:<p>Fluvalinate is a synthetic chemical compound and can be commonly used to control varroa mites in honey bee colonies.</p>Fórmula:C26H22ClF3N2O3Cor e Forma:SolidPeso molecular:502.91Pirtobrutinib
CAS:<p>Pirtobrutinib: a selective, non-covalent BTK inhibitor effective against BTK C481 mutations, causing tumor regression in lymphoma models.</p>Fórmula:C22H21F4N5O3Pureza:99.76% - 99.94%Cor e Forma:SolidPeso molecular:479.43RU 58668
CAS:<p>Pure antiestrogen that downregulates estrogen receptor expression</p>Fórmula:C34H43F5O5SPureza:98%Cor e Forma:SolidPeso molecular:658.76MMP-7-IN-2
CAS:<p>MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.</p>Fórmula:C28H40ClF3N6O9SPureza:97.82%Cor e Forma:SolidPeso molecular:729.17MMP-9 Inhibitor I
CAS:<p>MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively).</p>Fórmula:C27H33N3O5SCor e Forma:SolidPeso molecular:511.63Dibenamine hydrochloride
CAS:<p>Dibenamine hydrochloride is a competitive and irreversible blocking agent of the β-adrenergic receptor.</p>Fórmula:C16H19Cl2NPureza:96.43%Cor e Forma:Oily Liquid SolidPeso molecular:296.23LX7101
CAS:LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).Fórmula:C23H29N7O3Pureza:99.08%Cor e Forma:SolidPeso molecular:451.52ND-378
CAS:<p>ND-378 is a potent and selective inhibitor of MMP-2 with no inhibition on MMP-9 and MMP-14.</p>Fórmula:C18H19NO4S2Pureza:98%Cor e Forma:SolidPeso molecular:377.48Cipemastat
CAS:<p>Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).</p>Fórmula:C22H36N4O5Pureza:98%Cor e Forma:SolidPeso molecular:436.55Etidocaine Hydrochloride
CAS:<p>Etidocaine Hydrochloride (W19053) is a long-acting anesthetic and a blocker of the voltage-gated sodium channel.</p>Fórmula:C17H29ClN2OPureza:99.86%Cor e Forma:SolidPeso molecular:312.88Thioquinapiperifil
CAS:<p>Thioquinapiperifil is a type of phosphodiesterase-5 (PDE-5) inhibitor found in dietary supplements.</p>Fórmula:C24H28N6OSPureza:98%Cor e Forma:SolidPeso molecular:448.58Collagen proline hydroxylase inhibitor
CAS:<p>Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.</p>Fórmula:C18H18N4O4Pureza:98%Cor e Forma:SolidPeso molecular:354.36Dothiepin
CAS:<p>Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing</p>Fórmula:C19H21NSPureza:98%Cor e Forma:SolidPeso molecular:295.44MMP13-IN-3
CAS:<p>MMP13-IN-3 is an oral, selective MMP-13 inhibitor with IC50 of 1 nM, >1000x selective, for osteoarthritis treatment.</p>Fórmula:C24H22N4O5Pureza:99.76%Cor e Forma:SolidPeso molecular:446.46MMP3 inhibitor 1
CAS:<p>MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).</p>Fórmula:C23H31N3O6SPureza:98%Cor e Forma:SolidPeso molecular:477.57PIM447
CAS:<p>PIM447 (LGH447) is a pan-PIM kinase inhibitor with anti-tumor and bone protective effects. PIM447 reduces the viability, and motility of HuH6 cell.</p>Fórmula:C24H23F3N4OPureza:98.97%Cor e Forma:SolidPeso molecular:440.46MMP-7-IN-3
CAS:<p>MMP-7-IN-3 (compound 15) is a potent and selective MMP-7 inhibitor, inhibiting renal fibrosis in a unilateral ureteral obstruction mouse model.</p>Fórmula:C34H43ClF3N7O9SPureza:99.915%Cor e Forma:SolidPeso molecular:818.26Bufuralol (hydrochloride)
CAS:<p>Bufuralol hydrochloride is a potent, non-selective, orally active β-blocker with partial agonist effects and a CYP2D6 probe.</p>Fórmula:C16H24ClNO2Cor e Forma:SolidPeso molecular:297.82Naxagolide free base
CAS:<p>Naxagolide is a sustained release formulation. It is a dopamine agonist.</p>Fórmula:C15H21NO2Pureza:98%Cor e Forma:SolidPeso molecular:247.33Celiprolol hydrochloride
CAS:Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.Fórmula:C20H33N3O4·HClCor e Forma:White Crystalline SolidPeso molecular:415.96Ro 32-7315
CAS:<p>Ro 32-7315 is a selective inhibitor of ADAM17.</p>Fórmula:C22H35N3O5SPureza:98%Cor e Forma:SolidPeso molecular:453.6Caroverine
CAS:Caroverine is a potential chemotherapeutical agent in HNSCC cell lines.Fórmula:C22H27N3O2Cor e Forma:SolidPeso molecular:365.47Frovatriptan
CAS:<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Fórmula:C14H17N3OCor e Forma:SolidPeso molecular:243.3MMP-3 Inhibitor VIII
CAS:<p>Matrix metalloproteinase-3 (MMP-3), also known as stromelysin-1, is a critical enzyme involved in tissue remodeling and repair through its role in degrading extracellular matrix proteins, facilitating cell migration. This enzyme has been implicated in various physiological processes including vascular remodeling associated with aneurysm formation, wound healing, the progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII, a cell-permeable sulfonamide-based hydroxamic acid, effectively inhibits MMP-3 by binding to its active site (Ki = 23 nM), thus blocking its enzymatic activity. Additionally, this inhibitor has been demonstrated to suppress the activity of mouse macrophage metalloelastase MME/MMP-12, with an IC50 value of 13 nM, highlighting its potential utility in research on tissue remodeling and disease processes involving MMPs.</p>Fórmula:C20H26N2O5SCor e Forma:SolidPeso molecular:406.5KB-R7785
CAS:<p>KB-R7785 is a novel ADAM12/MMP inhibitor improving heart function and insulin sensitivity by blocking HB-EGF and TNF-alpha.</p>Fórmula:C18H27N3O4Cor e Forma:SolidPeso molecular:349.42Gisadenafil
CAS:<p>Gisadenafil (UK-369003) is a selective inhibitor of phosphodiesterase 5 (PDE5) with an IC50 of 3.6 nM and prevents degradation of cGMP.</p>Fórmula:C23H33N7O5SPureza:98.82% - 99.50%Cor e Forma:SolidPeso molecular:519.62Zandelisib
CAS:<p>Zandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.</p>Fórmula:C31H38F2N8OPureza:99.88%Cor e Forma:SolidPeso molecular:576.68Gepirone
CAS:<p>Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.</p>Fórmula:C19H29N5O2Pureza:99.35% - 99.89%Cor e Forma:SolidPeso molecular:359.47Ro 31-9790
CAS:<p>Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).</p>Fórmula:C15H29N3O4Pureza:98%Cor e Forma:SolidPeso molecular:315.41FGIN-1-27
CAS:<p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>Fórmula:C28H37FN2OPureza:99.86%Cor e Forma:SolidPeso molecular:436.6Carmoxirole hydrochloride
CAS:<p>Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.</p>Fórmula:C24H27ClN2O2Pureza:99.37% - 99.62%Cor e Forma:SolidPeso molecular:410.94Inz-1
CAS:<p>Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human.</p>Fórmula:C16H14N2O2Pureza:99.55% - 99.88%Cor e Forma:SolidPeso molecular:266.29(Rac)-Lonafarnib
CAS:<p>(Rac)-Lonafarnib is a racemic FTase inhibitor, effective against H-ras, K-ras, N-ras (IC50: 1.9, 5.2, 2.8 nM), and has anti-HDV properties.</p>Fórmula:C27H31Br2ClN4O2Cor e Forma:SolidPeso molecular:638.82ICI 204448
CAS:<p>ICI 204448 is a potent and peripherally selective κ-opioid agonist.</p>Fórmula:C23H26Cl2N2O4Cor e Forma:SolidPeso molecular:465.37TP0556351
CAS:<p>TP0556351: potent MMP2 inhibitor with 0.2 nM IC50, reduces collagen in pulmonary fibrosis mice.</p>Fórmula:C50H70N10O16Pureza:98%Cor e Forma:SolidPeso molecular:1067.15Quizalofop
CAS:<p>Quizalofop (Xylafop) is a reagent of biochemical.</p>Fórmula:C17H13ClN2O4Pureza:97.14%Cor e Forma:SolidPeso molecular:344.75Ubrogepant
CAS:<p>Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.</p>Fórmula:C29H26F3N5O3Pureza:99.452% - 99.78%Cor e Forma:SolidPeso molecular:549.54Maralixibat Chloride
CAS:<p>Maralixibat Chloride (LUM001 chloride), an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.</p>Fórmula:C40H56ClN3O4SPureza:99.19% - 99.65%Cor e Forma:SolidPeso molecular:710.41Elobixibat
CAS:<p>Elobixibat (A 3309) blocks IBAT in mice/humans/dogs (IC50: 0.13/0.53/5.8 nM); used for constipation research.</p>Fórmula:C36H45N3O7S2Pureza:97.43% - 98.03%Cor e Forma:SolidPeso molecular:695.89Aderamastat
CAS:<p>Aderamastat (FP-025) is an orally active matrix metalloproteinase 12 (MMP-12) inhibitor indicated for the study of allergic asthma, COPD and pulmonary fibrosis.</p>Fórmula:C21H18N2O4SPureza:99.35%Cor e Forma:SolidPeso molecular:394.447'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole
CAS:<p>7'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole (7'-MPB) is a benzimidazole derivative that is used as a medicine. It is made from recycled chemicals and has shown to have industrial applications as a catalyst for cyclization reactions. 7'-MPB is also used in the production of benzenesulfonic acid, which is an organic solvent. This chemical has been shown to be effective against high blood pressure, but has not been tested on humans yet. Telmisartan, which belongs to the angiotensin II receptor blocker class of drugs, can inhibit the synthesis of prostaglandins.</p>Fórmula:C18H18N4Pureza:Min. 95%Peso molecular:290.36 g/mol4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride
CAS:<p>4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride is a drug product. It is used as an analytical standard and in the development of drugs. The metabolite of 4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride, 4-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-N-(4-nitrophenyl)benzamide, has been shown to inhibit the production of cytokines IL6 and TNFα by human monocytes, macrophages, and dendritic cells. Metabolism studies have shown that 4-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-N</p>Fórmula:C13H20ClNO3Pureza:Min. 95%Peso molecular:273.76 g/molCollagen proline hydroxylase inhibitor-1
CAS:<p>Collagen proline hydroxylase inhibitor-1 具有抗纤维增生活性。</p>Fórmula:C24H21N5O4Pureza:99.62%Cor e Forma:SolidPeso molecular:443.451-(6-Chloro-9H-carbazol-2-yl)ethanone
CAS:<p>1-(6-Chloro-9H-carbazol-2-yl)ethanone is a chemical substance that belongs to the class of synthetic drugs. It is used as a pharmaceutical intermediate in the production of other chemical substances, including antibiotics and antihypertensives. 1-(6-Chloro-9H-carbazol-2-yl)ethanone has been shown to be metabolized by cytochrome P450 enzymes and by glucuronidases or esterases. This product can also be used as an impurity standard for HPLC analyses of fluoroquinolones.</p>Fórmula:C14H10ClNOPureza:Min. 95%Peso molecular:243.69 g/molSitagliptin impurity E
CAS:<p>Sitagliptin impurity E is an inhibitor of dipeptidyl peptidase-4 (DPP-IV) that is used as a hypoglycemic agent. Sitagliptin impurity E has been shown to increase the glucose-lowering effect in diabetic patients with type 2 diabetes mellitus. It is also effective in reducing postprandial glucose and insulin levels. Sitagliptin impurity E has been shown to increase the concentration of insulin in plasma for up to 24 hours after administration, which suggests that it may be useful for the treatment of metabolic disorders such as obesity and type 2 diabetes mellitus.</p>Fórmula:C16H15F6N5OPureza:Min. 95%Peso molecular:407.31 g/mol
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