Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65630 produtos de "Derivados de Quinazolina e Quinolina"
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Oxcarbazepine
CAS:<p>Applications A metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug. A keto derivative of Carbamazepine. Used as an anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Dam., M., et al.: Epilepsy Res., 3, 70 (1989); Beydoun, A., et al.: Expert Opin. Pharmacother., 3, 59 (2001);<br></p>Fórmula:C15H12N2O2Cor e Forma:Light YellowPeso molecular:252.275-(CHLOROMETHYL)-3-(3-PHENOXYPYRIDIN-4-YL)-1,2,4-OXADIAZOLE
Pureza:95.0%Peso molecular:287.70001220703125(E)-3-(3-(3,4-dimethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl)acrylic acid
CAS:Pureza:98%Peso molecular:350.3739929199219Ref: 10-F521408
1gA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar250mgA consultarEverolimus
CAS:Produto Controlado<p>Impurity Everolimus EP Impurity C<br>Stability Hygroscopic<br>Applications Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),<br></p>Fórmula:C53H83NO14Pureza:~90%Cor e Forma:NeatPeso molecular:958.22Nadifloxacin
CAS:<p>Applications Fluorinated quinolone antibacterial (topical).<br>References Kurokawa, I., et al.: J. Am. Acad. Dermatol., 25, 674 (1991),<br></p>Fórmula:C19H21FN2O4Cor e Forma:White To Off-WhitePeso molecular:360.382-Methoxy Phenothiazine
CAS:<p>Applications An impurity of Methotrimeprazine (M260785).A derivative of Phenothiazine (P318040) exhibits tuberculostatic activity.<br>References Waisser, K., et al.: Folia. Pharm. Univ. Carol., 18, 41 (1995)<br></p>Fórmula:C13H11NOSCor e Forma:Grey To BrownPeso molecular:229.306-Des(1-methyl-2-benzimidazolyl)-6-carboxy Telmisartan
CAS:Produto Controlado<p>Impurity Telmisartan EP Impurity E / Telmisartan Diacid<br>Applications An impurity of Telmisartan (T017000).<br>References Yu, W. et al.: Youji Huaxue, 26, 318 (2006);<br></p>Fórmula:C26H24N2O4Cor e Forma:NeatPeso molecular:428.49N1,N3-Bis(descyclohexyl) N1,N3-Bis(trans-4-Hydroxy-Cyclohexyl) Daprodustat
CAS:Produto Controlado<p>Impurity Daprodustat Bishydroxylated Metabolite<br>Applications Daprodustat Metabolite is a metabolite of Daprodustat (D193368). Daprodustat is a novel HIF (Hypoxia inducible factor)-prolyl hydroxylase inhibitor.<br>References Olson, E., et al.: Vasc. Med., 19, 473 (2014);<br></p>Fórmula:C19H27N3O8Cor e Forma:NeatPeso molecular:425.434-(4-Methylpiperidin-4-yl)morpholinedihydrochloride
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:257.200012207031253-Hydroxy Carbamazepine
CAS:<p>Applications A metabolite of Carbamazepine (C175840).<br>References Park, B., et al.: Biochem. Pharmacol., 36, 581 (1987), Yamazaki, H., et al.: Drug Metab. Dispos., 27, 1260 (1999), Dieckhaus, C., et al.: Chem. Res. Toxicol., 14, 958 (2001),<br></p>Fórmula:C15H12N2O2Cor e Forma:NeatPeso molecular:252.27Olanzapine
CAS:Produto Controlado<p>Applications Olanzapine is a serotonin (5-HT2) and dopamine (D1/D2) receptor antagonist with anticholinergic activity. Antipsychotic. Neuroprotective product.<br>References Moore, N.A., et al.: Curr. Opin Invest. Drugs, 2, 281 (1993), Baldwin, D.S. and Montgomery, S.A.: Int. Clin. Psychopharmacol., 10, 239 (1995), Tohen, M., et al.: Am. J. Psychiatry, 156, 702 (1999)<br></p>Fórmula:C17H20N4SCor e Forma:Light Yellow CrystallinePeso molecular:312.434-Chloro-2-methyl-5-(thiophen-2-yl)thieno[2,3-d]pyrimidine
CAS:Pureza:95%Peso molecular:266.7600097656254-phenyl-3-(2-thienyl)-1,2,4-triazoline-5-thione 98%
CAS:Pureza:98.0%Peso molecular:259.35000610351565-p-Tolyl-1H-pyrazole-3-carboxylic acid methyl ester
CAS:Pureza:95.0%Peso molecular:216.24000549316406ETHYL 2-(3-METHYL-4-OXO-3,4-DIHYDROPHTHALAZIN-1-YL)ACETATE
CAS:Pureza:95.0%Peso molecular:246.26600646972656Ref: 10-F505729
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarLoxapine-d8 Hydrochloride (Major)
CAS:Produto ControladoFórmula:C18H10D8ClN3O·xHClCor e Forma:White To Off-WhitePeso molecular:372.323-(3-([1,1'-biphenyl]-4-yl)-1-phenyl-1h-pyrazol-4-yl)acrylic acid
CAS:Pureza:97%Peso molecular:366.423-[[[2-[(Diaminomethylene]amino-4-thiazolyl]thio]propionitrile
CAS:Produto ControladoFórmula:C8H11N5S2Cor e Forma:NeatPeso molecular:241.341,1’-N-[Methylenebis(sulphanediylethylene)]bis(N’-methyl-2-nitroethene-1,1-diamine
CAS:Produto Controlado<p>Impurity Ranitidine EP Impurity J<br>Applications 1,1’-N-[Methylenebis(sulphanediylethylene)]bis(N’-methyl-2-nitroethene-1,1-diamine (Ranitidine EP Impurity J) is a Ranitidine (R120000) impurity.<br></p>Fórmula:C11H22N6O4S2Cor e Forma:Off-White To BeigePeso molecular:366.46Hydroxy Flutamide
CAS:Produto Controlado<p>Applications The active metabolite of the widely used non-steroidal antagonist Flutamide (F598850). Shown to be an antianhydrogen.<br>References Katchen, B., et al.: J. Clin. Endocrinol. Metab., 41, 373 (1975), Fau, D., et al.: J. Pharmacol. Exp. Ther., 269, 954 (1994), Anzenbacher, P., et al.: Drug Metab. Dispos., 30, 100 (2002), Norlin, M., et al.: J. Lipid Res., 43, 721 (2002),<br></p>Fórmula:C11H11F3N2O4Cor e Forma:Off White SolidPeso molecular:292.216-Bromo-2-phenylquinoline-4-carboxylic acid
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:328.16500854492195-Imino-N,4-bis(4-phenyl)-4,5-dihydro Riluzole
Produto ControladoFórmula:C16H10F6N4O2SCor e Forma:NeatPeso molecular:436.33N-(2-chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)nicotinamide
CAS:Pureza:98%Peso molecular:302.7600097656254-Amino-3,5-dichloropyridine
CAS:<p>Applications 4-Amino-3,5-dichloropyridine is a metabolite of the selective phosphodiesterase 4 (PDE4) inhibitor, Roflumilast (R639700).<br>References Jeffrey, A.D. et al.: Drug Chem. Toxicol., 25, 93 (2002); Cassidy, K.C. et al.: J. Pharmac. Biomed. Anal., 22, 869 (2000);<br></p>Fórmula:C5H4Cl2N2Cor e Forma:NeatPeso molecular:163.03-(5-azetidin-3-yl-1,2,4-oxadiazol-3-yl)pyridine dihydrochloride
CAS:Pureza:95.0%Peso molecular:275.1300048828125Bupivacaine-d9 Hydrochloride
CAS:Produto Controlado<p>Applications Labelled Bupivacaine (B689560). Sodium channel blocker, local anesthetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wilson, T.D., et al.: Anal. Profiles Drug Subs., 19, 59 (1990), McClellan, K.J., et al.: Drugs, 56, 355 (1998),<br></p>Fórmula:C182H9H19N2O·ClHCor e Forma:NeatPeso molecular:333.94S-[5-Chloro-3-(trifluoromethyl)pyrid-2-yl]-S-methylsulfilimine 2,4,6-trimethylbenzenesulfonate
CAS:Fórmula:C16H18ClF3N2O3S2Pureza:95.0%Peso molecular:442.94-Pyrazol-1-ylmethyl-phenylamine
CAS:Fórmula:C10H11N3Pureza:98%Cor e Forma:SolidPeso molecular:173.219A77 1726-d4
CAS:Produto Controlado<p>Applications The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function.<br>References Kirsch, B.M., et al.: Arthritis Research and Therapy, 7, 3, R694, (2005)<br></p>Fórmula:C122H4H5F3N2O2Cor e Forma:Off-WhitePeso molecular:274.23Cinitapride Tartrate
CAS:<p>Applications Cinitapride Tartrate is the salt analogue of Cinitapride (C441990), a novel prokinetic benzamide-stimulating gastrointestinal motility agent and antiucer agent. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors.<br>References Alarcon de la Lastra, C. et al.: Pharmacol, 54, 193 (1997); Robert, M. et al.: Drug Metab. Disp., 35, 1149 (2007); Alarcon de la Lastra, C. et al.: Inflam. Res., 47, 131 (1998)<br></p>Fórmula:C21H30N4O4·C4H6O6Cor e Forma:NeatPeso molecular:552.57Sibutramine, Hydrochloride Monohydrate
CAS:Produto ControladoFórmula:C17H26ClN·ClH·H2OCor e Forma:Off White SolidPeso molecular:334.324-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide
CAS:<p>Applications 4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide is an impurity of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Fórmula:C15H17N3O2SCor e Forma:White To Light YellowPeso molecular:303.381-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine
CAS:Produto Controlado<p>Applications 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine is an intermediate used to prepare nonracemic γ-bicyclic heteroarylpiperazine- and heteroarylpiperidine-substituted prolinylthiazolidines as selective and orally active dipeptidylpeptidase 4 inhibitors for use as antidiabetic agents.<br>References Yoshida, T., et al.: Bioorg. Med. Chem., 20, 5705 (2012)<br></p>Fórmula:C14H18N4Cor e Forma:NeatPeso molecular:242.32
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![3-[[[2-[(Diaminomethylene]amino-4-thiazolyl]thio]propionitrile](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD416372.webp&w=3840&q=75)
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