Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65630 produtos de "Derivados de Quinazolina e Quinolina"
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Thioridazine-d3 Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Dopamine receptor blocker; parent compound of sulforidazine and mesoridazine. Antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goldenthal, E.I., Toxicol. Appl. Pharmacol., 18, 185 (1971), Abdel-Moety, E.M., et al.: Anal. Profile Drug Subs., 18, 459 (1989),<br></p>Fórmula:C21D3H23N2S2·ClHCor e Forma:NeatPeso molecular:410.05Terbufoxon Sulfoxide
CAS:Produto Controlado<p>Applications Terbufoxon Sulfoxide is a metabolite of Terbufoxon (T109075), a pesticide used in the protection of fruit and vegetable crops against insects. Acetylcholinesterase inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rahman, Md. M. et al.: Food Chem., 133, 604 (2012); Stojan, J. et al.: Biochem., 5599 (2008); Polgar, L. et al.: J. Chrom. A., 1249, 83 (2012);<br></p>Fórmula:C9H21O4PS2Cor e Forma:NeatPeso molecular:288.36Tazarotene-d8
CAS:Produto Controlado<p>Applications Labelled Tazarotene (T010050). An acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ. Antiacne; antipsoriatic. Used in treatment of photodamaged skin.<br>References Tang-Liu, D.D.-S., et al.: Clin. Pharmacokinet., 37, 273 (1999), Roeder, A., et al.: Skin Pharmacol. Physiol., 17, 111 (2004),<br></p>Fórmula:C21H13D8NO2SCor e Forma:YellowPeso molecular:359.51Fluconazole
CAS:<p>Applications Fluconazole is used as an antifungal.<br>References Richard, K. et al.: Antimicrob. Ag. Chemother., 27, 832 (1985),<br></p>Fórmula:C13H12F2N6OCor e Forma:NeatPeso molecular:306.276-(4-AMINO-4-METHYLPIPERIDIN-1-YL)-3-(2,3-DICHLOROPHENYL)PYRAZIN-2-AMINE
CAS:Pureza:95.0%Peso molecular:352.260009765625Ref: 10-F544411
1gA consultar5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar250mgA consultar4-Chloro-4'-fluorobutyrophenone
CAS:Produto Controlado<p>Applications 4-Chloro-4'-fluorobutyrophenone (cas# 3874-54-2) is a compound useful in organic synthesis.<br></p>Fórmula:C10H10ClFOCor e Forma:NeatPeso molecular:200.641-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic Acid
CAS:Produto ControladoFórmula:C11H10FNO3Cor e Forma:Off-WhitePeso molecular:223.23,7-Dihydro-3-methyl-1,7-bis(5-oxohexyl)-1H-purine-2,6-dione
CAS:Fórmula:C18H26N4O4Cor e Forma:NeatPeso molecular:362.422-[3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoic Acid Methyl Ester
CAS:Produto Controlado<p>Applications An intermediate in the synthesis of Montelukast.<br>References Labelle, M., et al.: Bioorg. Med. Chem. Lett., 4, 463 (1994), Roberge, C., et al.: J. Ferment. Bioeng., 81, 530 (1996), Shafiee, A., et al.: App. Microbiol. Biotechnol., 49, 709 (1998),<br></p>Fórmula:C28H22ClNO3Cor e Forma:NeatPeso molecular:455.933-Hydroxybenzaldehyde
CAS:<p>Impurity Roxatidine Impurity 3<br>Applications 3-Hydroxybenzaldehyde (cas# 100-83-4) is a compound useful in organic synthesis.<br></p>Fórmula:C7H6O2Cor e Forma:Off-WhitePeso molecular:122.122-Hydroxymethyl Loratadine
CAS:Produto Controlado<p>Impurity Loratadine 2-Hydroxymethyl Impurity (USP)<br>Applications A usual impurity in Loratadine syrup formulations, a nonsedating-type histamine H1-receptor. Loratadine 2-Hydroxymethyl Impurity (USP).<br>References Okamoto, T., et al.: Chem. Pharm. Bull ., 7, 130 (1959), Eyjolfsson, R., et al.: Pharmazie, 58, 154 (2003),<br></p>Fórmula:C23H25ClN2O3Cor e Forma:NeatPeso molecular:412.91Amantadine
CAS:Produto Controlado<p>Applications Amantadine is useful in biology studies. Particularly it has been used for solid-state NMR and membrane protein studies.<br>References Shigeta, A., et al.: New Developments in NMR, 20, 457 (2019)<br></p>Fórmula:C10H17NCor e Forma:White To Off-WhitePeso molecular:151.2510β-Hydroxy Naloxone
CAS:Produto Controlado<p>Impurity Naloxone EP Impurity F<br>Applications 10β-Hydroxy Naloxone is hydroxylated analog of the opioid antagonist Naloxone (N285000).<br>References Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967), McNicholas, L.F., et al.: Drugs, 27, 81 (1984), Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985), Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993)<br></p>Fórmula:C19H21NO5Cor e Forma:NeatPeso molecular:343.371-Acetyl-4-(4-hydroxyphenyl)piperazine
CAS:Produto Controlado<p>Applications 1-Acetyl-4-(4-hydroxyphenyl)piperazine is an intermediate used to prepare Ketoconazole (K186000) which inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo.<br>References Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)<br></p>Fórmula:C12H16N2O2Cor e Forma:WhitePeso molecular:220.272-(4-Hydroxybenzyl)-N,5-bis-(4-fluorophenyl)-5-hydroxypentanamide
CAS:<p>Applications 2-(4-Hydroxybenzyl)-N,5-bis-(4-fluorophenyl)-5-hydroxypentanamide is an ring-opened impurity of Ezetimibe (E975000).<br>References Raman, B. et al.: J. Pharmac. Biomed. Anal., 52, 73 (2010);<br></p>Fórmula:C24H23F2NO3Cor e Forma:WhitePeso molecular:411.44(1-[[2-[(2-Aminophenyl)amino]-5-methyl-3-thienyl]carbonyl]-4-methyl-piperazine
CAS:Produto Controlado<p>Applications 1-[[2-[(2-Aminophenyl)amino]-5-methyl-3-thienyl]carbonyl]-4-methyl-piperazine is an impurity of Olanzapine (O253750), a serotonin (5-HT2) and dopamine (D1/D2) receptor antagonist with anticholinergic activity.<br>References Moore, N.A., et al.: Curr. Opin Invest. Drugs, 2, 281 (1993), Baldwin, D.S. and Montgomery, S.A.: Int. Clin. Psychopharmacol., 10, 239 (1995), Tohen, M., et al.: Am. J. Psychiatry, 156, 702 (1999)<br></p>Fórmula:C17H22N4OSCor e Forma:NeatPeso molecular:330.45Thioacetic Acid
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Thiacetic Acid is a commonly used reagent in organic synthesis for the introduction of thiol groups in molecules.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chapman, J.H. et al.: J. Chem. Soc., 579 (1950); Hoque, A., et al.: Bioorg. Med. Chem. Lett., 22, 6770 (2012)<br></p>Fórmula:C2H4OSCor e Forma:NeatPeso molecular:76.124-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-ol
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:319.7200012207031Argatroban monohydrate
CAS:Produto ControladoFórmula:C23H36N6O5S·H2OCor e Forma:NeatPeso molecular:526.65Nilotinib-d6
CAS:Produto Controlado<p>Applications Nilotinib-d6, is the labeled analogue of Nilotinib (N465300), which might be useful in treatment of chronic myelogenous leukemia. It is a COVID19-related research product.<br>References Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),<br></p>Fórmula:C282H6H16F3N7OCor e Forma:Off-White To Light BeigePeso molecular:535.55Amisulpride N-Oxide
CAS:Produto Controlado<p>Impurity Amisulpride EP Impurity F<br>Applications Amisulpride N-Oxide is an impurity of Amisulpride (A633250). Amisulpride N-Oxide was identified as a photodegradation product of Amisulpride. Amisulpride EP Impurity F<br>References Moulin, A., et al.: Eur. J. Drug Metab. Pharmcokinet., 3, 507 (1991), Chatterjee, B., et al.: J. Biotechnol., 3, 235 (2008), Breier, A., et al.: J. Pharm. Biomed. Anal., 46, 250 (2008),<br></p>Fórmula:C17H27N3O5SCor e Forma:White To Off-WhitePeso molecular:385.48N,N'-Dicyclohexylurea
CAS:Produto Controlado<p>Impurity Lomustine USP Related Compound C<br>Applications N,N'-Dicyclohexylurea,is a substituted Urea (U822500) compound, which has shown to be a potent inhibitor of juvenile hormone epoxide hydrolase (JHEH) of the tobacco hornworm M. sexta. Lomustine USP Related Compound C.<br>References Garriga, M., et al.: Chemosphere, 82, 1604 (2011)<br></p>Fórmula:C13H24N2OCor e Forma:Light YellowPeso molecular:224.34Bupivacaine Hydrochloride
CAS:Produto Controlado<p>Applications Bupivacaine HCl (cas# 18010-40-7) is a useful research chemical.<br></p>Fórmula:C18H28N2O·ClHCor e Forma:NeatPeso molecular:324.89Fingolimod Palmitate Amide
CAS:Produto Controlado<p>Applications Fingolimod Palmitate Amide is an impurity of Fingolimod (F805000, HCl salt), a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.<br>References Brinkmann, V., et al.: Transplantation, 72, 764 (2001), Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002), Mtaloubian, M., et al.: Nature, 427, 355 (2004),<br></p>Fórmula:C35H63NO3Cor e Forma:NeatPeso molecular:545.88Quinfamide
CAS:Produto Controlado<p>Applications Quinfamide is an anti-amebic agent used to treat tropical parasitic infections.<br>References Slighter, R., et al.: Parasitol., 81, 157 (1980), Parthasarathy, P., et al.: Eur. J. Med. Chem., 28, 195 (1993), Padilla, N., et al.: Clin. Drug Invest., 20, 89 (2000),<br></p>Fórmula:C16H13Cl2NO4Cor e Forma:White To Light BeigePeso molecular:354.185''''-Methyl-apixaban
CAS:Produto Controlado<p>Impurity Apixaban<br>Applications Analytical standard impurity of drug.<br></p>Fórmula:C26H27N5O4Cor e Forma:NeatPeso molecular:473.524Lomerizine Dihydrochloride
CAS:Produto Controlado<p>Applications A diphenylpiperazine calcium channel blocker. A selective cerebral vasodilator. Antimigraine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kanazawa, T., et al.: J. Cardiovasc. Pharmacol., 16, 430 (1990), Hara, H., et al.: Arch. Int. Pharmacodyn, 304, 206 (1990), Danielisova, V., et al.: Neurochem. Res., 19, 1503 (1994)<br></p>Fórmula:C27H30F2N2O3·2ClHCor e Forma:NeatPeso molecular:541.46Anagliptin
CAS:Produto Controlado<p>Applications Anagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction. It also attenuates atherosclerosis in male apolipoprotein E-deficient mice.<br>References Ervinna, N., et al.: Endocrinology, 154, 1260 (2013); Furuta, S., et al.: Eur. J. Drug Metab. Ph., 38, 87 (2013)<br></p>Fórmula:C19H25N7O2Cor e Forma:NeatPeso molecular:383.45rac-cis-N-Desmethyl Sertraline-d4 Hydrochloride
CAS:Produto Controlado<p>Applications A labelled metabolite of Sertraline. N-Desmethyl Sertraline is significantly less active analogue as compared to the methylated compound, Sertraline.<br>References Welch, W.M., et al.: J. Med. Chem. 27, 1508 (1984)<br></p>Fórmula:C16H12D4Cl3NCor e Forma:NeatPeso molecular:332.69Dasatinib Dimeric Impurity
CAS:Produto ControladoFórmula:C36H34Cl2N12O2S2Cor e Forma:White To BeigePeso molecular:801.77(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid
CAS:Produto Controlado<p>Impurity Ambrisentan Hydroxy Acid Impurity<br>Applications (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid is used in analytical studies for chiral discrimination of α-functionalized acids. Ambrisentan Hydroxy Acid Impurity<br>References Jain, N., et al.: Tetrahedron, 70, 4343 (2014)<br></p>Fórmula:C16H16O4Cor e Forma:NeatPeso molecular:272.30KAD-1229 Calcium Hydrate
CAS:Produto ControladoFórmula:C19H24NO3·Ca·2H2OCor e Forma:NeatPeso molecular:704.91Hydroxy Ritonavir
CAS:Produto Controlado<p>Impurity Ritonavir EP Impurity E<br>Applications Hydroxy Ritonavir (Ritonavir EP Impurity E) is a metabolite of Ritonavir (R535000), HIV-1 protease inhibitor. It is a COVID19-related research product.<br>References Eagling, V., et al.: Br. J. Clin. Pharmacol., 48, 543 (1999), Eagling, V., et al.: Xenobiotica, 32, 1 (2002), Meaden, E., et al.: J. Antimicrob. Chemother., 50, 583 (2002), Treijtel, N., et al.: Drug Metab. Dispos., 33, 1325 (2005),<br></p>Fórmula:C37H48N6O6S2Cor e Forma:NeatPeso molecular:736.94Intedanib
CAS:Produto Controlado<p>Applications It is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. An antitumor agent.<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>Fórmula:C31H33N5O4Cor e Forma:NeatPeso molecular:539.624-(3,5-dimethyl-1H-pyrazol-1-yl)benzenesulfonyl chloride
CAS:Cor e Forma:SolidPeso molecular:270.73001098632815-(1-Methyl-4-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol
CAS:Produto Controlado<p>Applications 5-(1-Methyl-4-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol is a derivative of Cyproheptadine (C989200) which is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. Cyproheptadine is a 5-HT2/5-HT1C serotonin receptor antagonist; H1 histamine receptor antagonist; antipruritic.<br>References Marchei, E., et al.: J. Pharm. Biomed. Anal., 41, 1633 (2006); de-Benedictis, F., et al.: Allergy, 63, 1395 (2008); Feas, X., et al.: J. Pharm. Biomed. Anal., 50, 1044 (2009); Yu, C., et al.: Talanta, 2011, 83, 1376 (2011);<br></p>Fórmula:C21H23NOCor e Forma:NeatPeso molecular:305.411-(3-Carboxy-2-pyridyl)-4-methyl-2-phenylpiperazine
CAS:Produto Controlado<p>Applications Mirtazapine (M365000) impurity.<br>References Reddy, T. et al.; J. Liq. Chromatogr. R. T. 31, 1204 (2008)<br></p>Fórmula:C17H19N3O2Cor e Forma:NeatPeso molecular:297.35Clozapine N-Oxide-d8
CAS:Produto ControladoFórmula:C18H11D8ClN4OCor e Forma:Yellow To Dark YellowPeso molecular:350.874-Chloro Bupropion Fumarate
CAS:Produto Controlado<p>Applications A 4-chloro substituted analogue of Bupropion (B689625) used in the preparation of compounds for indirect dopamine agonist pharmacotherapy for treating cocaine, methamphetamine, nicotine, and other drugs of abuse addiction.<br>References Carroll, F.I. et al.: J. Med. Chem., 52, 6768 (2009);<br></p>Fórmula:C13H17Cl2NO·C4H4O4Cor e Forma:NeatPeso molecular:390.26Demethyl Benzydamine Hydrochloride
CAS:Produto Controlado<p>Applications A metabolite of Benzydamine (B209950).<br>References Kataoka, S., et al.: Chem. Pharma. Bull., 21, 358 (1973),<br></p>Fórmula:C18H22ClN3OCor e Forma:Off White SolidPeso molecular:331.842,3,5-Trimethylpyridine N-Oxide
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Intermediate in the preparation of Omeprazole metabolites<br></p>Fórmula:C8H11NOCor e Forma:Off-White To Light BrownPeso molecular:137.18Omeprazole Sulfide Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Omeprazole Sulfide Hydrochloride is a metabolite of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Fórmula:C17H19N3O2S·HClCor e Forma:NeatPeso molecular:329.42 + 36.46Defluoro-6-chloro Norfloxacin Hydrochloride
CAS:Fórmula:C16H18ClN3O3·HClCor e Forma:Off-WhitePeso molecular:372.254-AMINO-3-CHLOROPICOLINIC ACID METHYL ESTER
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:186.60000610351562N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine Formamide Hydrochloride
CAS:Produto Controlado<p>Impurity Alfuzosin Hydrochloride EP Impurity E<br>Applications Alfuzosin (A532000) impurity. Alfuzosin (A532000) is an α1-Adrenoceptor antagonist structurally similar to Prozosin. Antihypertensive. Used in treatment of benign prostatic hypertrophy. (Alfuzosin Hydrochloride EP Impurity E )<br>References Ramage, A.G., et al.: Eur. J. Pharmacol., 129, 307 (1986), Deering, A.H.,: Brit. J. Clin. Pharmacol., 25, 417 (1988), Priolo, L.D., et al.: Eur. J. Clin. Pharmacol., 35, 25 (1988),<br></p>Fórmula:C15H21N5O3·HClCor e Forma:White To Off-WhitePeso molecular:319.37 + (36.46)
![2-[3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoic Acid Methyl Ester](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC380010.webp&w=3840&q=75)
![1-[[2-[(2-Aminophenyl)amino]-5-methyl-3-thienyl]carbonyl]-4-methyl-piperazine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FA622450.webp&w=3840&q=75)
![5-(1-Methyl-4-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM321260.webp&w=3840&q=75)
