Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65630 produtos de "Derivados de Quinazolina e Quinolina"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
N-(2-Amino-4-thiazolyl)acetyl Mirabegron
CAS:Fórmula:C26H28N6O3S2Cor e Forma:NeatPeso molecular:536.669N-Nitroso-Atomoxetine
Produto ControladoFórmula:C17H20N2O2Cor e Forma:Off WhitePeso molecular:284.3535-Formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid
CAS:Produto Controlado<p>Applications 5-Formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid is useful for the synthesis of 5-Bromo-7-azaindolin-2-one derivatives which possesses in vitro activity against selected cancer cell lines.<br>References Zhang, J., et al.: Molecules, 21, 1674-1683 (2016);<br></p>Fórmula:C8H9NO3Cor e Forma:NeatPeso molecular:167.16(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol
CAS:<p>Stability Hygroscopic<br>Applications (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol was used to preapare AZD6140 as an orally active reversible P2Y12 receptor antagonist for prevention of thrombosis.<br>References Zhang, H., et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012);<br></p>Fórmula:C8H15NO3Cor e Forma:NeatPeso molecular:173.213-Hydroxy Imiquimod
CAS:Produto Controlado<p>Applications 4-Amino-β-methyl-1H-imidazo[4,5-c]quinoline-1-propanol, is an aryl ether substituted imidazoquinolines, which can be used in the design of immunomodulating agents for use as vaccine adjuvants and anticancer treatments.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shi, C., et al.: ACS Med. Chem. Lett., 3, 501 (2012);<br></p>Fórmula:C14H16N4OCor e Forma:NeatPeso molecular:256.310β-Hydroxy Naloxone
CAS:Produto Controlado<p>Impurity Naloxone EP Impurity F<br>Applications 10β-Hydroxy Naloxone is hydroxylated analog of the opioid antagonist Naloxone (N285000).<br>References Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967), McNicholas, L.F., et al.: Drugs, 27, 81 (1984), Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985), Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993)<br></p>Fórmula:C19H21NO5Cor e Forma:NeatPeso molecular:343.37Olanzapine LIP 1 Acetyl
CAS:<p>Applications Olanazpine LIP 1 Acetyl is an Olanazpine impurity. Olanazpine is an antipsychotic medicine.<br>References Perera, V., et al.: Br. J. Clin. Pharmacol., 78, 800 (2014); Pratt, N., et al.: Pharmacoepidemiol. Drug Saf., 22, 915 (2013)<br></p>Fórmula:C18H20N4OSCor e Forma:YellowPeso molecular:340.444-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-ol
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:319.7200012207031Argatroban monohydrate
CAS:Produto ControladoFórmula:C23H36N6O5S·H2OCor e Forma:NeatPeso molecular:526.65Nilotinib-d6
CAS:Produto Controlado<p>Applications Nilotinib-d6, is the labeled analogue of Nilotinib (N465300), which might be useful in treatment of chronic myelogenous leukemia. It is a COVID19-related research product.<br>References Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),<br></p>Fórmula:C282H6H16F3N7OCor e Forma:Off-White To Light BeigePeso molecular:535.55Amisulpride N-Oxide
CAS:Produto Controlado<p>Impurity Amisulpride EP Impurity F<br>Applications Amisulpride N-Oxide is an impurity of Amisulpride (A633250). Amisulpride N-Oxide was identified as a photodegradation product of Amisulpride. Amisulpride EP Impurity F<br>References Moulin, A., et al.: Eur. J. Drug Metab. Pharmcokinet., 3, 507 (1991), Chatterjee, B., et al.: J. Biotechnol., 3, 235 (2008), Breier, A., et al.: J. Pharm. Biomed. Anal., 46, 250 (2008),<br></p>Fórmula:C17H27N3O5SCor e Forma:White To Off-WhitePeso molecular:385.48Fingolimod Palmitate Amide
CAS:Produto Controlado<p>Applications Fingolimod Palmitate Amide is an impurity of Fingolimod (F805000, HCl salt), a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.<br>References Brinkmann, V., et al.: Transplantation, 72, 764 (2001), Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002), Mtaloubian, M., et al.: Nature, 427, 355 (2004),<br></p>Fórmula:C35H63NO3Cor e Forma:NeatPeso molecular:545.88Quinfamide
CAS:Produto Controlado<p>Applications Quinfamide is an anti-amebic agent used to treat tropical parasitic infections.<br>References Slighter, R., et al.: Parasitol., 81, 157 (1980), Parthasarathy, P., et al.: Eur. J. Med. Chem., 28, 195 (1993), Padilla, N., et al.: Clin. Drug Invest., 20, 89 (2000),<br></p>Fórmula:C16H13Cl2NO4Cor e Forma:White To Light BeigePeso molecular:354.185''''-Methyl-apixaban
CAS:Produto Controlado<p>Impurity Apixaban<br>Applications Analytical standard impurity of drug.<br></p>Fórmula:C26H27N5O4Cor e Forma:NeatPeso molecular:473.524Lomerizine Dihydrochloride
CAS:Produto Controlado<p>Applications A diphenylpiperazine calcium channel blocker. A selective cerebral vasodilator. Antimigraine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kanazawa, T., et al.: J. Cardiovasc. Pharmacol., 16, 430 (1990), Hara, H., et al.: Arch. Int. Pharmacodyn, 304, 206 (1990), Danielisova, V., et al.: Neurochem. Res., 19, 1503 (1994)<br></p>Fórmula:C27H30F2N2O3·2ClHCor e Forma:NeatPeso molecular:541.462,3,4-Trimethoxybenzaldehyde
CAS:Produto Controlado<p>Applications 2,3,4-Trimethoxybenzaldehyde is a trimethoxylated aromatic aldehyde. 2,3,4-Trimethoxybenzaldehyde is an impurity of the anti-anginal drug Trimetazidine (T795610).<br>References Medenica, M.B. et al.: J. Chrom. Sci., 46, 430 (2008);<br></p>Fórmula:C10H12O4Cor e Forma:Off-WhitePeso molecular:196.201-Hydroxycyclopentyl 2-chlorophenyl Ketone
CAS:Produto ControladoFórmula:C12H13ClO2Cor e Forma:Colourless To Light YellowPeso molecular:224.685,5-Diphenyl Hydantoin Sodium
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 5,5-Diphenyl Hydantoin Sodium salt reduces incidence of grand mal seizures; appears to stabilize excitable membranes perhaps through effects on Na+, K+, and Ca2+ channels.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Faucette, S., et al.: J. Pharmacol. Exp. Ther., 320, 72 (2007), Guo, D., et al.: J. Biol. Chem., 282, 36766 (2007), Merrell, M., et al.: Drug Metab. Dispos., 36, 1716 (2008),<br></p>Fórmula:C15H11N2O2·NaCor e Forma:NeatPeso molecular:274.25Gabapentin-d6 Hydrochloride
CAS:Produto Controlado<p>Applications Gabapentin Hydrochloride is a salt analogue of Gabapentin-d6 (G117253), a labelled amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.<br>References Vollmer, K.O. et al.: Arzneim.-Forsch., 36, 830 (1986); Saletu, B., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 362 (1986)<br></p>Fórmula:C9H11D6NO2·HClCor e Forma:NeatPeso molecular:213.73Deferiprone-d3 3-O-β-D-Glucuronide Sodium Salt
CAS:Produto Controlado<p>Stability Very Hygroscopic<br>Applications A labelled metabolite of Deferiprone (D474000).<br>References Choudhury, R., et al.: Drug Metab. Dispos., 23, 314 (1995);<br></p>Fórmula:C13H13D3NNaO8Cor e Forma:Off-White To Light BeigePeso molecular:340.28Intedanib
CAS:Produto Controlado<p>Applications It is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. An antitumor agent.<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>Fórmula:C31H33N5O4Cor e Forma:NeatPeso molecular:539.624-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzaldehyde
CAS:<p>Impurity Bisoprolol EP Impurity L (Metoprolol EP Impurity C)<br>Stability Hygrscopic<br>Applications 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzaldehyde (Bisoprolol EP Impurity L (Metoprolol EP Impurity C)) is a Metoprolol impurity .<br>References Baldwin, J.J. , et al.: J. Med. Chem., 29, 1065 (1986), Ravelet, C., et al.: J. Sep. Sci., 29, 1322 (2006),<br></p>Fórmula:C13H19NO3Cor e Forma:NeatPeso molecular:237.29a-Phenyl-a-ethylacetamide
CAS:Produto Controlado<p>Impurity Primidone USP Related Compound C<br>Applications α-Phenyl-α-ethylacetamide acts as a hypolipaemic agent used in the treatment of high levels of cholesterol.<br>References Marrero-Ponce, Y. et al.: Bioorg. Med. Chem., 13, 2881 (2005); Gohil, V. et al: Nat. Biotech., 28, 249 (2010);<br></p>Fórmula:C10H13NOCor e Forma:NeatPeso molecular:163.22Difenoconazole
CAS:<p>Applications Pestanal is an fungicide that exhibits a broad spectrum of activities against a wide variety of fungi including members of the Aschomycetes, Basidomycetes and Deuteromycetes families.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pinto, A., et al.: Sci. Tot. Environ., 435, 402 (2012); Bakirci, G.T., et al.: Food. Chem., 135, 1901 (2012); Sharma, A.K., et al.: Pestology., 36, 47 (2012);<br></p>Fórmula:C19H17Cl2N3O3Cor e Forma:ColourlessPeso molecular:406.26N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
CAS:Produto Controlado<p>Impurity Bicalutamide Oxirane Impurity / Bicalutamide Epoxide Impurity<br>Applications N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, is an intermediate in synthesis of more complex pharmaceutical compounds. It is used in the synthesis of potential impurities of Bicalutamide (B382000), which is an oral nonsteroidal, anti-androgen drug used for prostate cancer.<br>References Nandu Baban, B., et al.: Synthetic Communications, 39, 1516 (2009);<br></p>Fórmula:C12H9F3N2O2Cor e Forma:NeatPeso molecular:270.211H-Benzimidazole-4-methyl-2-propyl-6-carboxylic Acid
CAS:Produto ControladoFórmula:C12H14N2O2Cor e Forma:NeatPeso molecular:218.256-chloro-2-(3-methylphenyl)quinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:297.739990234375Suprofen
CAS:<p>Applications Prostaglandin biosynthesis inhibitor. Analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Niemegeers, C.J.E., et al.: Arzneim.-Forsch., 25, 1537 (1975),<br></p>Fórmula:C14H12O3SCor e Forma:BeigePeso molecular:260.31S-(-)-Etomidate
CAS:Produto Controlado<p>Applications Etomidate (E933300) is a hypnotic. This is a stereoisomer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goetz, E., et al.: Anaesthesist, 23, 331 (1974), Chang, Z. L., et al.: Anal. Profiles Drug Subs., 12, 191 (1983),<br></p>Fórmula:C14H16N2O2Cor e Forma:NeatPeso molecular:244.294-tert-Butylaminoethyl-2-methylphenol
CAS:Produto Controlado<p>Impurity Salbutamol EP Impurity H<br>Applications 4-tert-Butylaminoethyl-2-methylphenol (Salbutamol EP Impurity H) is an impurity of Albuterol Sulfate (Salbutamol Sulfate) (A514500). Albuterol impurity H.<br>References Epshtein, N., et al.: Pharm. Chem. J., 38, 212 (2004), Erram, S., et al.: J. Pharm. Biomed. Anal., 40, 864 (2006),<br></p>Fórmula:C13H21NOCor e Forma:NeatPeso molecular:207.31N-(4-Aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide
CAS:Fórmula:C14H22N4OCor e Forma:Off-White To BeigePeso molecular:262.35Amantadine-d15 Hydrochloride
CAS:Produto Controlado<p>Applications NMDA-receptor antagonist. Antiviral; antiparkinsonian.<br>References Vernier, V.G., et al; Toxicol. Appl. Pharmacol., 15, 642 (1969), Kirschbaum, J., et al.: Anal. Profiles Drug Subs., 12, 1 (1983),<br></p>Fórmula:C102H15H2NCor e Forma:NeatPeso molecular:166.34Omeprazole Sulfide Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Omeprazole Sulfide Hydrochloride is a metabolite of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Fórmula:C17H19N3O2S·HClCor e Forma:NeatPeso molecular:329.42 + 36.46Rivastigmine-d4 Tartrate Salt
CAS:Produto Controlado<p>Applications Rivastigmine-d4 Tartrate Salt, is the labeled analogue of Rivastigmine Tartrate Salt (R541000), a brain selective acetylcholinesterase inhibitor. Nootropic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Fórmula:C18H24D4N2O8Cor e Forma:NeatPeso molecular:404.45Indomethacin-d4
CAS:Produto Controlado<p>Applications Nonsteroidal anti-inflammatory agent (NSAID).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)<br></p>Fórmula:C192H4H12ClNO4Cor e Forma:White To Off-WhitePeso molecular:361.81L-Homoserine Lactone, Hydrochloride
CAS:Produto Controlado<p>Applications L-Homoserine Lactone, Hydrochloride (cas# 2185-03-7) is a compound useful in organic synthesis.<br></p>Fórmula:C4H7NO2·ClHCor e Forma:NeatPeso molecular:137.56rac Talinolol-d5
CAS:Produto Controlado<p>Applications Labelled Talinolol. Selective β1-adrenergic blocker structurally related to Practolol. Antihypertensive; antiarrhythmic.<br>References Assmann, I., et al.: Curr. Med. Res. Opin., 13, 325 (1995), Trausch, B., et al.: Biopharm. Drug Dispos., 16, 403 (1995),<br></p>Fórmula:C202H5H28N3O3Cor e Forma:Off White CrystallinePeso molecular:368.52Nizatidine-d3
CAS:Produto Controlado<p>Applications Labelled Nizatidine. Histamine H2-receptor antagonist related to Ranitidine (R120000). Antiulcerative.<br>References Callaghan, J.T., et al.: Clin. Pharmacol. Ther., 37, 162 (1985), Secor, J.W., et al.: Br. J. Clin. Pharmacol., 20, 710 (1985), Knadler, M.P., et al.: Drug Metab. Dispos., 14, 175 (1986), Wozniak, T.J., et al.: Anal. Profiles Drug Subs., 19, 397(1990)<br></p>Fórmula:C12D3H18N5O2S2Cor e Forma:Light Yellow SolidPeso molecular:334.48Demethylpiperazinyl 7-Desoxo 7-Thioxosildenafil Sulfonic Acid
CAS:Produto ControladoFórmula:C17H20N4O4S2Cor e Forma:Off White SolidPeso molecular:408.50Carisoprodol
CAS:Produto Controlado<p>Applications Muscle relaxant (skeletal).<br>References Musso, D., et al.: J. Med. Chem. 46, 399 (2003), Newman, P., et al.: Eur. J. Clin. Pharm., 23, 31 (1982).<br></p>Fórmula:C12H24N2O4Cor e Forma:White To Off-WhitePeso molecular:260.33Clioquinol
CAS:Produto Controlado<p>Applications Clioquinol is used as an antiparasitic compound, known to induce apoptosis in leukemia and myeloma cells.<br>References Cao, B. et al.: J. Biol. Chem., 288, 34181 (2013); Chen, Z. et al.: Eur J. Med. Chem., 68, 454 (2013);<br></p>Fórmula:C9H5ClINOCor e Forma:NeatPeso molecular:305.504-(6,7-DIMETHOXY-QUINOLIN-4-YLOXY)-PHENYLAMINE
CAS:Pureza:95.0%Cor e Forma:Liquid, No data available.Peso molecular:296.32598876953125EPZ 6438
CAS:Produto Controlado<p>Applications EPZ 6438 is a potent and selective inhibitor of EZH2.<br>References Knutson, S., et al.: Nat. Chem. Biol., 8, 890 (2012)<br></p>Fórmula:C34H44N4O4Cor e Forma:NeatPeso molecular:572.74Captopril Disulfide
CAS:<p>Impurity Captopril EP Impurity A<br>Applications Captopril Disulfide (Captopril EP Impurity A) is a metabolite of Captopril. A new antihypertensive agent.<br>References Sprague, P., et al.: Perspect. Drug Discovery Des., 3, 21 (1995), Cushman, D., et al.: Nat. Med., 5, 1110 (1999), Jacoby, E., et al.: Drug News Perspect., 16, 93 (2003), Lengauer, T., et al.: Drug Discovery Today, 9, 27 (2004),<br></p>Fórmula:C18H28N2O6S2Cor e Forma:WhitePeso molecular:432.55Levofloxacin-d3
CAS:Produto Controlado<p>Applications Levofloxacin-d3, is the labeled analogue of Levofloxacin (L360000), an antibiotic used against gram-negative organisms.<br>References Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992), North, D.S., et al.: Pharmacotherapy, 18, 915 (1998), Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003),<br></p>Fórmula:C18H17D3FN3O4Cor e Forma:NeatPeso molecular:364.39
![4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzaldehyde](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FH946735.webp&w=3840&q=75)
![N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC987585.webp&w=3840&q=75)
