Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65630 produtos de "Derivados de Quinazolina e Quinolina"
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De-4-fluoro 5-Fluoro Chidamide
CAS:<p>Applications De-5-fluoro 4-Fluorochidamide is an analogue of Chidamide (CAS 743420-02-0), a hitsone deacetylase inhibitor (HDACI) that enhances gemcitabine (G305000) cytotoxicity in pancreatic cancer cells.<br>References Qiao, Z., et. al.: Biochem. Bioph. Res. Co., 434, 95 (2013)<br></p>Fórmula:C22H19FN4O2Cor e Forma:Off White PowderPeso molecular:390.41(2-Cyclohexyl)ethyl 5-(1,3-dioxolan-2-yl)-2-thienyl ketone
CAS:Pureza:97.0%Peso molecular:294.4100036621094Tryptophol
CAS:Produto Controlado<p>Applications Tryptophol is a metabolite formed in the liver after disulfiram treatment that induces sleep in humans. It is also a secondary product of alcoholic fermentation.<br>References Cornford, E.M., et al.: J Clin Invest, 63, 1241-1248 (1979)<br></p>Fórmula:C10H11NOCor e Forma:NeatPeso molecular:161.24-Amino-3,5-dichloropyridine
CAS:<p>Applications 4-Amino-3,5-dichloropyridine is a metabolite of the selective phosphodiesterase 4 (PDE4) inhibitor, Roflumilast (R639700).<br>References Jeffrey, A.D. et al.: Drug Chem. Toxicol., 25, 93 (2002); Cassidy, K.C. et al.: J. Pharmac. Biomed. Anal., 22, 869 (2000);<br></p>Fórmula:C5H4Cl2N2Cor e Forma:NeatPeso molecular:163.0S-[5-Chloro-3-(trifluoromethyl)pyrid-2-yl]-S-methylsulfilimine 2,4,6-trimethylbenzenesulfonate
CAS:Fórmula:C16H18ClF3N2O3S2Pureza:95.0%Peso molecular:442.9Ref: 10-F601808
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarAmbrisentan Acyl β-D-Glucuronide
CAS:Produto Controlado<p>Applications A glucuronide metabolite of Ambrisentan (A575860).<br></p>Fórmula:C28H30N2O10Cor e Forma:NeatPeso molecular:554.55N-2 Trityl Olmesartan Medoxomil
CAS:<p>Impurity Olmesartan Medoxomil EP Impurity D<br>Applications Olmesartan medoxomil intermediate.<br>References Birkenhager, W., et al.: J. Hypertens, 17, 873 (1999), Whittaker, A., et al.: Br. J. Cardiol., 12, 125 (2005),<br></p>Fórmula:C48H44N6O6Cor e Forma:White To Light YellowPeso molecular:800.904-[6-(3-Methoxy-phenyl)-pyridin-3-yl]-pyrimidin-2-ylamine
Pureza:95.0%Peso molecular:278.31500244140625Dechloro Haloperidol
CAS:Produto Controlado<p>Impurity Haloperidol EP Impurity A<br>Applications Haloperidol impurity B.<br>References Janssen, P.A.J., et al.: J. Med. Pharm. Chem., 1, 281 (1959), Moerlein, S.M., et al.: J. Med. Chem., 28, 1319 (1985),<br></p>Fórmula:C21H24FNO2Cor e Forma:NeatPeso molecular:341.42Hydroxy Flutamide
CAS:Produto Controlado<p>Applications The active metabolite of the widely used non-steroidal antagonist Flutamide (F598850). Shown to be an antianhydrogen.<br>References Katchen, B., et al.: J. Clin. Endocrinol. Metab., 41, 373 (1975), Fau, D., et al.: J. Pharmacol. Exp. Ther., 269, 954 (1994), Anzenbacher, P., et al.: Drug Metab. Dispos., 30, 100 (2002), Norlin, M., et al.: J. Lipid Res., 43, 721 (2002),<br></p>Fórmula:C11H11F3N2O4Cor e Forma:Off White SolidPeso molecular:292.21[2-oxo-5-(trifluoromethyl)-1(2H)-pyridinyl]acetic acid
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:221.13499450683594Ref: 10-F314892
1gA consultar5gA consultar2.5gA consultar50mgA consultar100mgA consultar500mgA consultar2-[1-Methyl-5-(trifluoromethyl)pyrazol-3-yl]-thiophene-5-carboxaldehyde
CAS:Fórmula:C10H7F3N2OSCor e Forma:SolidPeso molecular:260.231,1’-N-[Methylenebis(sulphanediylethylene)]bis(N’-methyl-2-nitroethene-1,1-diamine
CAS:Produto Controlado<p>Impurity Ranitidine EP Impurity J<br>Applications 1,1’-N-[Methylenebis(sulphanediylethylene)]bis(N’-methyl-2-nitroethene-1,1-diamine (Ranitidine EP Impurity J) is a Ranitidine (R120000) impurity.<br></p>Fórmula:C11H22N6O4S2Cor e Forma:Off-White To BeigePeso molecular:366.46N-Formyl Oxcarbazepine
CAS:Produto Controlado<p>Applications N-Formyl Oxcarbazepine is an impurity of the anticonvulsant Oxcarbazepine (O869250).<br></p>Fórmula:C16H12N2O3Cor e Forma:NeatPeso molecular:280.283',4'-Dihydroxyacetophenone
CAS:Produto Controlado<p>Applications 3',4'-Dihydroxyacetophenone is an active constituent of Chinese medicine and also has antimelanogenic actiivity.<br>References Kim. Y., et al.: Biosci., Biotech., Biochem., 70, 532 (2006); Yang, D., et al.: Prostaglandins, 38, 497 (1989)<br></p>Fórmula:C8H8O3Cor e Forma:NeatPeso molecular:152.154-Methyl-2-(4-methyl-2-pyridinyl)-1-(2-oxo-2-phenylethyl)pyridinium bromide
Peso molecular:383.28900146484375Donafenib
CAS:<p>Donafenib(Bay 43-9006 (D3)) is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3,</p>Fórmula:C21H13ClD3F3N4O3Pureza:99.88%Cor e Forma:SolidPeso molecular:467.84Cimetidine Sulfoxide
CAS:Produto Controlado<p>Impurity Cimetidine EP Impurity E<br>Applications Cimetidine Sulfoxide (Cimetidine EP Impurity E) is a metabolite of the H2-receptor antagonist Cimetidine (C441650). Cimetidine Sulfoxide is detected in the blood and urine of patients with kidney diseases.<br>References Luksa, J. et al.: J. Chrom. B Biomed. Appl., 667, 321 (1995); Lee, R.M. et al.: J. Chrom. Biomed. Appl., 146, 354 (1978);<br></p>Fórmula:C10H16N6OSCor e Forma:NeatPeso molecular:268.34N-De(4-sulfonamidophenyl)-N’-(4-sulfonamidophenyl) Celecoxib
CAS:Produto Controlado<p>Impurity Celecoxib EP Impurity B<br>Applications N-De(4-sulfonamidophenyl)-N’-(4-sulfonamidophenyl) Celecoxib (Celecoxib EP Impurity B) is an isomeric impurity of Celecoxib (C251000) with selective inhibitory activity against human cyclooxygenase-2. USP Celecoxib Related Compound B<br>References Talley, J.J. et al.: Actual. Chim. Therap., 25, 123 (1999); Rao, R. et al.: Anal. Sci., 22, 1257 (2006);<br></p>Fórmula:C17H14F3N3O2SCor e Forma:NeatPeso molecular:381.371-(2,6-Dimethylphenyl)-1,5,6,7-tetrahydro-2H-azepin-2-one
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications 1-(2,6-Dimethylphenyl)-1,5,6,7-tetrahydro-2H-azepin-2-one is an impurity of the local anesthetic Levobupivacaine (B689546).<br></p>Fórmula:C14H17NOCor e Forma:NeatPeso molecular:215.29Loxapine-d8 Hydrochloride (Major)
CAS:Produto ControladoFórmula:C18H10D8ClN3O·xHClCor e Forma:White To Off-WhitePeso molecular:372.329,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid(RS-Ofloxacin Carboxylic Acid)
CAS:Fórmula:C13H9F2NO4Cor e Forma:Off-WhitePeso molecular:281.211-(4-Chlorophenyl)-5-(furan-2-yl)-1h-pyrazole-3-carboxylic acid
CAS:Pureza:95%Peso molecular:288.69000244140625Danofloxacin
CAS:<p>Applications Danofloxacin is a broad spectrum fluoroquinolone antibacterial compound.<br>References Golet, E., et al.: Anal. Chem., 73, 3632 (2001); Golet, E., et al.: Environ. Sci. Technol., 36, 3645 (2002); Huet, A., et al.: J. Agric. Food Chem., 54, 2822 (2006);<br></p>Fórmula:C19H20FN3O3Cor e Forma:Off-WhitePeso molecular:357.38Levetiracetam Carboxylic Acid
CAS:Produto ControladoFórmula:C8H13NO3Cor e Forma:White To Off-WhitePeso molecular:171.19Epinephrine Sulfonic Acid-d3
CAS:Produto Controlado<p>Applications A labelled Epinephrine (E588585) derivative formed in injection solutions and eye drops during sterilization and storage of L-Epinephrine Bitartrate.<br>References De Mol, N.J. et al.: Pharmac. Week., 117, 1 (1982); Liu, C. et al.: Yao. Fen. Zaz., 2, 200 (1982);<br></p>Fórmula:C9H10D3NO5SCor e Forma:Light BrownPeso molecular:250.29Temocapril Hydrochloride
CAS:Produto Controlado<p>Applications Angiotensin-converting enzyme (ACE) inhibitor. Hydrolyzed in vivo to the active diacid metabolite.<br>References Qizumi, K., et al.: Jpn. J. Pharmacol., 48, 349 (1988), Arita, M., et al.: Clin. Exp. Pharmacol. Physiol., 21, 195 (1994), Tokunaga, S., et al.: Drug Invest., 7, 161 (1994)<br></p>Fórmula:C23H28N2O5S2·ClHCor e Forma:NeatPeso molecular:513.07Ritonavir Ethyl Carbamate
Produto Controlado<p>Applications Ritonavir Ethyl Carbamate is an impurity of the selective HIV protease inhibitor Ritonavir (R535000).<br>References Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005), Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788 (2006)<br></p>Fórmula:C31H40N4O6SCor e Forma:NeatPeso molecular:596.737Desmethyl Doxylamine Oxalate
CAS:Produto Controlado<p>Impurity Carbinoxamine Related Compound C<br>Applications Desmethyl Doxylamine Oxalate is an impurity of Doxylamine (D562000), an H1 Histamine receptor antagonist used as a antihistaminic and sedative agent.<br>References Pande, S.S., et al.: Int. J. Pharmtech. Res., 3, 209 (2011); Tiford, C.H., et al.: J. Am. Chem. Soc., 70, 4001 (1948);<br></p>Fórmula:C16H20N2O·C2H2O4Cor e Forma:NeatPeso molecular:346.374-Methyl-2-(1-methyl-piperidin-4-yl)-2H-pyrazol-3-ylamine
CAS:Fórmula:C10H18N4Pureza:97%Cor e Forma:SolidPeso molecular:194.282
![S-[5-Chloro-3-(trifluoromethyl)pyrid-2-yl]-S-methylsulfilimine 2,4,6-trimethylbenzenesulfonate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF008266.webp&w=3840&q=75)
![4-[6-(3-Methoxy-phenyl)-pyridin-3-yl]-pyrimidin-2-ylamine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF511274.webp&w=3840&q=75)
![[2-oxo-5-(trifluoromethyl)-1(2H)-pyridinyl]acetic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF314892.webp&w=3840&q=75)
![2-[1-Methyl-5-(trifluoromethyl)pyrazol-3-yl]-thiophene-5-carboxaldehyde](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF008394.webp&w=3840&q=75)
![1,1’-N-[Methylenebis(sulphanediylethylene)]bis(N’-methyl-2-nitroethene-1,1-diamine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM304100.webp&w=3840&q=75)
![5,6-DIMETHYL-2-(PYRIDIN-3-YL)-1H-BENZO[D]IMIDAZOLE](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF473562.webp&w=3840&q=75)
![9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid(RS-…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD445745.webp&w=3840&q=75)
