Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65573 produtos de "Derivados de Quinazolina e Quinolina"
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2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone
CAS:Produto ControladoFórmula:C6H8O4Cor e Forma:NeatPeso molecular:144.134-(QUINOLIN-4-YL)PIPERIDINE-4-CARBONITRILE HCL
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:273.7600097656256,7-Bis(benzyloxy)-4-oxo-1,4-dihydroquinoline-3-carbonitrile
CAS:Pureza:98%Peso molecular:382.41900634765625(S)-Naproxen-d3
CAS:Produto Controlado<p>Applications (S)-Naproxen-d3 is the labeled analogue of (S)-Naproxen (N377520), an anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)<br></p>Fórmula:C142H3H11O3Cor e Forma:NeatPeso molecular:233.281-(1-Ethyl-3-methyl-1 H -pyrazol-4-yl)-ethylamine
CAS:Fórmula:C8H15N3Cor e Forma:SolidPeso molecular:153.229Dehydro Levetiracetam
CAS:<p>Impurity Levetiracetam EP Impurity B<br>Stability Light Sensitive<br>Applications Dehydro Levetiracetam (Levetiracetam EP Impurity B) is an impurity of Levetiracetam (L331500) which is an (S)-enantiomer of Etiracetam (E932970) and the ethyl analog of Piracetam (P500800). Used as an anticonvulsant.<br>References Gower, A. J., et al.: Eur. J. Pharmacol., 222, 193 (1992); Kasteleijn-Noist Trenite, D.G.A., et al.: Epilepsy Res., 25, 225 (1996); Patsalos, P.N., et al.: Pharmacol. Ther., 85, 77 (2000)<br></p>Fórmula:C8H12N2O2Cor e Forma:WhitePeso molecular:168.19Dasatinib N-Oxide
CAS:<p>Applications An oxidative metabolite of Dasatinib (M5 metabolite). It is a COVID19-related research product.<br>References Cashman, J.R., et al.: Chem. Res. Toxicol., 8, 165 (1995), Aasmoe, L., et al.: Toxicol. Appl. Pharmacol., 150, 86 (1998), Galetin, A., et al.: J. Pharmacol. Exp. Ther., 314, 180 (2005), Christopher, L.J., et al.: Drug Metab. Dispos., 36, 1357 (2008),<br></p>Fórmula:C22H26ClN7O3SCor e Forma:NeatPeso molecular:504.004-Amino-6-ethoxy-5-[[4-[(4R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]azo]-α-[[4-[(4R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazono]-2-pyrimidineacetonitrile
CAS:<p>Applications 4-Amino-6-ethoxy-5-[[4-[(4R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]azo]-α-[[4-[(4R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazono]-2-pyrimidineacetonitrile is a levosimendan dimer impurity, which is a bioactive enantiomer of racemate, Simendan. Positive inotropic agent with vasodilating activity. Cardiotonic.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995), Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996),<br></p>Fórmula:C30H30N12O3Cor e Forma:NeatPeso molecular:606.647-Hydroxy-N-des{[2-(2-hydroxy)ethoxy]ethyl} Quetiapine Dihydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A metabolite of Quetiapine.<br>References McConville, B., et al.: J. Clin. Psychiatry, 61, 252 (2000), Wong, Y., et al.: J. Clin. Psychopharmacol, 21, 89 (2001), Cooper, K., et al.: Eur. J. Clin. Pharmacol., 59, 51 (2003),<br></p>Fórmula:C17H17N3OS·2ClHCor e Forma:White To Off-WhitePeso molecular:384.323-Methyl-5-hydroxypyrazole
CAS:Fórmula:C4H6N2OPureza:95%Cor e Forma:White powderPeso molecular:98.105Avanafil
CAS:Produto Controlado<p>Applications A phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.<br>References Hatzimouratidis, K., et al.: Drugs, 68, 231 (2008);<br></p>Fórmula:C23H26ClN7O3Cor e Forma:WhitePeso molecular:483.95(2-Amino-1H-benzimidazol-6-yl)(4-fluorophenyl)-methanone
CAS:Produto Controlado<p>Applications The hydrolyzed form of Flubendazole (F418500), which is an anthelmintic.<br>References Thienpont, D., et al.: Arzneimittel-Forsch., 28, 605 (1978), Vanparijs, O., et al.: Vet. Parasitol, 5, 237 (1979),<br></p>Fórmula:C14H10FN3OCor e Forma:Off-WhitePeso molecular:255.25Pimobendan-d3
CAS:Produto Controlado<p>Applications Pimobendan-d3, is the labeled analogue of Pimobendan (P447500), a cardiotonic agent.<br>References Yokota, S. et al.: Yakuri Chiryo, 20, 1143 (1992); Yamamoto, M. et al.: Kank. Igaku Ken. Nenpo, 47, 155 (1996); Matsumoto, A. et al.: Cardiovas. Drugs Ther., 12, 595 (1998);<br></p>Fórmula:C19H15D3N4O2Cor e Forma:White To Light YellowPeso molecular:337.39(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifl
CAS:Produto Controlado<p>Applications Sitagliptin intermediate. A dipeptidyl peptidase-4 inhibitor and an anti-hypertensive agent for the treatment of diabetes and hypertension.<br>References Kim, D., et al.: J. Med. Chem., 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005), Bergman, A., et al: Clin. Ther., 28, 55 (2006)<br></p>Fórmula:C16H13F6N5OCor e Forma:WhitePeso molecular:405.30Rac Albuterol-d9
CAS:Produto Controlado<p>Applications A labelled β2-adrenoceptor agonist. Bronchodilator; tocolytic.<br>References Miyagawa, N., et al.: Biol. Pharm. Bull., 31, 2260 (2008), Gonzalez-Munoz, C., et al.: Eur. J. Pharmacol., 607, 151 (2009), Kern, C., et al.: J. Med. Chem., 52, 1773 (2009),<br></p>Fórmula:C132H9H12NO3Cor e Forma:White To YellowPeso molecular:248.37Carvedilol b-D-Glucuronide (mixture of diasteromers)
CAS:Produto Controlado<p>Applications A metabolite of Carvedilol (C184625).<br>References McGurk, K., et al.: Biochem. Pharmacol., 55, 1005 (1998), Tukey, R., et al.: Annu. Rev. Pharmacol. Toxicol., 40, 581 (2000), Bowalgaha, K., et al.: Br. J. Clin. Pharmacol., 52, 605 (2001), Richardson, T., et al.: Drug Metab. Dispos., 34, 351 (2006),<br></p>Fórmula:C30H34N2O10Cor e Forma:NeatPeso molecular:582.605-Nitro-2-furaldehyde
CAS:Produto Controlado<p>Applications 5-Nitro-2-furaldehyde is an intermediate in the synthesis of Nifurtimox (N458800), an antiprotozoal. Showing anti-Trypanosoma cruzi activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sastry, C.S.P., et. al.: Talanta, 41, 1957 (1994)<br></p>Fórmula:C5H3NO4Cor e Forma:NeatPeso molecular:141.082,4-Thioxylenol
CAS:Produto Controlado<p>Applications 2,4-Thioxylenol is a building block that has been used as a reactant for the preparation of Dibenzothiophene derivatives via palladium catalyzed aryl(alkyl)thiolation of unactivated arenes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Saravanan, P., Anbarasan, P.: Org. Lett., 16, 848 (2014)<br></p>Fórmula:C8H10SCor e Forma:NeatPeso molecular:138.23Thiourea
CAS:Produto Controlado<p>Applications Thiourea is used in biochemistry to increase the solubility (and resolution) of membrane proteins in two-dimensional electrophoresis. Thiourea is also used to treat thyrotoxicosis, a hypermetabolic clinical syndrome that is induced by multiple causes (Graves’ disease, hyperthyroidism, etc.).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jabbour, S.: Am. J. Clin. Dermatol., 4, 315 (2003); Himsworth, H.: Lancet, 242, 465 (1943); Rabilloud, T., et al.: Electrophoresis, 19, 758 (1998)<br></p>Fórmula:CH4N2SCor e Forma:WhitePeso molecular:76.124,4',4''-((1,3,5-TRIAZINE-2,4,6-TRIYL)TRIS(OXY))TRIBENZALDEHYDE
CAS:Pureza:95%Peso molecular:441.39898681640625Ref: 10-F852142
1g43,00€5g148,00€10g273,00€25g665,00€50g1.158,00€100g2.301,00€100mgA consultar250mgA consultarMildronate-d3
CAS:Produto Controlado<p>Stability Very Hygroscopic<br>Applications Mildronate-d3 is the labeled analogue of Mildronate (M344450), a novel pharmaceutical composition based on a reverse transcriptase inhibitor and meldonium. May contain a significant amount of water.<br></p>Fórmula:C6H11D3N2O2Cor e Forma:White To Off-WhitePeso molecular:149.2122-Hydroxy Mifepristone-d6
CAS:Produto Controlado<p>Applications A labelled metabolite of Mifepristone.<br>References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Fórmula:C29H29D6NO3Cor e Forma:NeatPeso molecular:451.63Cloperastine Fendizoate
CAS:<p>Stability Hygroscopic<br>Applications Cloperastine fendizoate is used in the treatment of chronic non-productive cough. Antitussive. it is the salt of Cloperastine (CAS:3703-76-2)<br>References Aliprandi, P. et al.: Clin. Drug Invest. 22, 209 (2002)<br></p>Fórmula:C20H24ClNO·C20H14O4Cor e Forma:White To Off-WhitePeso molecular:648.19(R)-1-(2-Bromopyridin-4-yl)ethanamine dihydrochloride
CAS:Pureza:97.0%Peso molecular:273.98001098632814-Defluoro 2-Fluoro Flunarizine Dihydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-Defluoro 2-Fluoro Flunarizine Dihydrochloride is an impurity of Flunarizine(F455200, Dihydrochloride), which is a calcium channel blocker. Flunarizine is a fluorinated derivative of Cinnarizine and a vasodilator (cerebral and peripheral).<br>References Desmedt, L.K., et al.: Arzneim.-Forsch., 25, 1408 (1975), Godfraind, T., et al.: Eur. J. Pharmacol., 53, 273 (1979), Nihard, P., et al.: Angiology, 33, 37 (1982), Holmes, B., et al.: Drugs, 27, 6 (1984)<br></p>Fórmula:C26H26F2N2HClCor e Forma:White SolidPeso molecular:404.49236461-(4,5-Dihydro-1H-imidazol-2-yl)-3,5-dimethyl-1H-pyrazole hydrobromide
CAS:Pureza:95.0%Peso molecular:245.12399291992188cis-Ambroxol Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications cis-Ambroxol Hydrochloride is a cis isomer of Ambroxol Hydrochloride (A575900 ), a metabolite of Bromohexine. Ambroxol Hydrochloride is a bronchosecretolytic drug.<br>References Jauch, R., et al.: Arzneim-Forsch., 13, 474 (1963)<br></p>Fórmula:C13H18Br2N2O·x(HCl)Cor e Forma:NeatPeso molecular:378.10 + x(36.46)7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
CAS:Produto Controlado<p>Applications Gefitinib intermediate.<br>References Kelly, L., et al.: Cancer Cell., 1, 421 (2002), Pandey, A., et al.: J. Med. Chem., 45, 3772 (2002), Ciardiello, F., et al.: Exp. Opin Emerg. Drugs, 8, 501 (2003), Caponigro, F., et al.: Curr. Opin Oncol., 16, 225 (2004),<br></p>Fórmula:C16H21N3O4Cor e Forma:NeatPeso molecular:319.365-azetidin-3-yl-3-(2-thienylmethyl)-1,2,4-oxadiazole hydrochloride
CAS:Pureza:95.0%Peso molecular:257.739990234375Etomidate Hydrochloride
CAS:Produto Controlado<p>Applications (cas# 53188-20-8) is a useful research chemical.<br></p>Fórmula:C14H17ClN2O2Cor e Forma:NeatPeso molecular:280.754-[2-(Dimethylamino)ethoxy]benzonitrile
CAS:Produto ControladoFórmula:C11H14N2OCor e Forma:NeatPeso molecular:190.2421-(2,4-Dichloro-phenoxymethyl)-1 H -pyrazole-3-carboxylic acid
CAS:Fórmula:C11H8Cl2N2O3Cor e Forma:SolidPeso molecular:287.11-Descarbamoyl-2-carbamoyl Methocarbamol
CAS:Produto Controlado<p>Applications An impurity of the muscle relaxant Methocarbamol (M225950) with lysosomal acid lipase inhibitory effects.<br>References Topliss, J., et al.: J. Med. Chem., 22, 1238 (1979); Rosenbaum, A.I. et al.: J. Med. Chem., 52, 5281 (2010);<br></p>Fórmula:C11H15NO5Cor e Forma:NeatPeso molecular:241.2402-Chloro-5-(5-Chloro-2-thienyl)pyridine
CAS:Fórmula:C9H5Cl2NSPureza:97.0%Cor e Forma:SolidPeso molecular:230.112-imino-5-oxo-4-(thiophen-2-yl)-3,4,5,6,7,8-hexahydro-2H-1-benzopyran-3-carbonitrile
CAS:Pureza:95+%Peso molecular:272.32000732421875(R)-3-Aminopiperidine Dihydrochloride
CAS:Produto Controlado<p>Applications (R)-3-Aminopiperidine Dihydrochloride has been used as a reactant for the preparation of dipeptidyl peptidase IV inhibitors derived from Alogliptin.<br>References Xie, Hui., et. al.: Eur. J. Med. Chem., 68, 312 (2013)<br></p>Fórmula:C5H14Cl2N2Cor e Forma:NeatPeso molecular:173.08Benzydamine N-Oxide
CAS:<p>Applications A metabolite of Benzydamine (B209950).<br>References Beaty, N., et al.: J. Biol. Chem., 255, 3817 (1980), Tugnait, M., et al.: Drug Metab. Dispos., 25, 524 (1997), Ubeaud, G., et al.: Eur. J. Pharm. Sci., 8, 255 (1999),<br></p>Fórmula:C19H23N3O2Cor e Forma:NeatPeso molecular:325.4N-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)-6-nitroquinazolin-4-amine
CAS:Pureza:95.0%Peso molecular:461.8800048828125Deferiprone-d3
CAS:Produto Controlado<p>Applications A chelator that could replace disferrioxamine. It is orally and parenterally effective in the removal of iron in vivo from rabbits and mice and also from transferrin and ferritin in vitro.<br>References Kontoghiorghes, G.J.: Lancet I, 817 (1985), Kontoghiorghes, G.J., et al.: Br. J. Haematol., 62, 607 (1986), Kontoghiorghes, G.J., et al.: Biochem. Biophys. Acta, 869, 141 (1986), Kontoghiorghes, G.J., et al.: Arzneim.-Forsch., 37, 1099 (1987),<br></p>Fórmula:C7H6D3NO2Cor e Forma:White To Off-WhitePeso molecular:142.175-Amino-3-methyl-1-quinolin-5-yl-1H-pyrazole-4-carbonitrile
Pureza:95.0%Peso molecular:249.276992797851565-Benzyl Benzydamine Hydrochloride
CAS:<p>Applications 5-Benzyl Benzydamine is an impurity of Benzydamine hydrochloride (B209950). Benzydamine impurity B.<br></p>Fórmula:C26H29N3O·ClHCor e Forma:NeatPeso molecular:435.994-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole Dihydrochloride
CAS:Produto ControladoFórmula:C7H13N3S·2ClHCor e Forma:NeatPeso molecular:244.19N-Methyl Omeprazole (Mixture of isomers with the methylated nitrogens of imidazole)
CAS:Produto Controlado<p>Applications Omeprazole (O635000) impurity.<br>References Allenmark, S., et al.: Anal. Biochem., 136, 293 (1984), Besancon, M., et al.: J. Biol. Chem., 272, 22438 (1997),<br></p>Fórmula:C18H21N3O3SCor e Forma:Off White SolidPeso molecular:359.44
![4-Amino-6-ethoxy-5-[[4-[(4R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]azo]-α-[[4-[(4…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FA607950.webp&w=3840&q=75)
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![(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-tri…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FO865000.webp&w=3840&q=75)
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![4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole Dihydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM286500.webp&w=3840&q=75)
