Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65497 produtos de "Derivados de Quinazolina e Quinolina"
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6-(methylsulfonyl)-N-(pyridin-3-ylmethyl)benzo[d]thiazol-2-amine
CAS:Pureza:95.0%Peso molecular:319.3999938964844Tezacaftor
CAS:<p>Applications Tezacaftor is used as a combination therapy with Ivacaftor for the treatment of patients with cystic fibrosis.<br>References Rowe, S. M., et al.: N. Engl. J. Med., 377, 2024 (2017); Dhooghe, B., et al.: Exp. Opin. Investig. Drugs, 25, 423 (2016)<br></p>Fórmula:C26H27F3N2O6Cor e Forma:White To Light YellowPeso molecular:520.5Fluconazole N-Oxide
CAS:Produto ControladoFórmula:C13H12F2N6O2Cor e Forma:Off WhitePeso molecular:322.273-[(pyridin-3-ylamino)carbonyl]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
CAS:Pureza:95.0%Peso molecular:258.2770080566406Gleevec-d8 Mesylate (Imatinib-d8 Mesylate)
CAS:Produto Controlado<p>Applications A deuterated tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.<br>References Schindler, T., et al.: Science, 289, 1938 (2000), Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001),<br></p>Fórmula:C292H8H23N7O·CH4O3SCor e Forma:NeatPeso molecular:597.76(Z)-1,2-Diphenyl-1-(4-hydroxyphenyl)-1-butene (contain up to 10% E-isomer)
CAS:Produto ControladoFórmula:C22H20OCor e Forma:NeatPeso molecular:300.394Desisopropyl Atrazine
CAS:Produto Controlado<p>Applications A metabolite of Atrazine (ATR) (A794600).<br>References Compton, D., et al.: Eur. J. Pharmacol., 110, 157 (1985), Das, P., et al.: Toxicol. Sci., 59, 127 (2001), Das, P., et al.: Life Sci., 73, 3123 (2003), Coban, A., et al.: J. Neurochem., 100, 1177 (2007),<br></p>Fórmula:C5H8ClN5Cor e Forma:Off-WhitePeso molecular:173.602-[2-[[4-[(5S)-5-[[[(5-Chloro-2-thienyl)carbonyl]amino]methyl]-2-oxo-3-oxazolidinyl]phenyl]amino]ethoxy]-acetic Acid Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 2-[2-[[4-[(5S)-5-[[[(5-chloro-2-thienyl)carbonyl]amino]methyl]-2-oxo-3-oxazolidinyl]phenyl]amino]ethoxy]-acetic Acid Hydrochloride is a metabolite of Rivaroxaban (R538000) which is a novel antithrombotic agent. Rivaroxaban is also a highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005)<br></p>Fórmula:C19H20ClN3O6S·HClCor e Forma:White Light RedPeso molecular:453.903646Ref: 10-F656645
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultar1,2,3,4-Tetrahydro-4,8-dihydroxy-2-methyl-isoquinoline
CAS:<p>Impurity Phenylephrine 4,6-DMTQ Impurity (Peak-2)<br>Applications Product formed during the decomposition of Phenylephrine<br>References Millard, B., et al.: J. Pharm. Pharmacol., 25, 24 (1973),<br></p>Fórmula:C10H13NO2Cor e Forma:Light YellowPeso molecular:215.68Mizolastine
CAS:<p>Applications A highly selective histamine H1-receptor antagonist (with no anticholinergic, antiadrenergic, or antiserotonin activity) for use in the treatment of allergic disorders, especially rhinitis and urticaria.<br>References Simons, F.E.R.: Clin. Alp. Allergy, 29, 3 (1999); Brostoff, J. et al.: Allergy, 51, 251 (1996); Gensthaler, B.M.: Pharm. Zeit., 143, 228 (1998);<br></p>Fórmula:C24H25FN6OCor e Forma:NeatPeso molecular:432.492,2-Diphenylhydantoic Acid
CAS:<p>Impurity Phenytoin USP Related Compound B<br>Applications 2,2-Diphenylhydantoic Acid is metabolite of Phenytoin, an anticonvulsant. Phenytoin USP Related Compound B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Van Espen, J., et al.: J. De. Pharma. De. Belgique., 7, 451 (1952); Stella, V., et al.: J. Org. Chem., 38, 1527 (1973);<br></p>Fórmula:C15H14N2O3Cor e Forma:NeatPeso molecular:270.28Benzocaine-d4
CAS:Produto Controlado<p>Applications Labelled Benzocaine (B202970). Benzocaine is used as an anesthetic (local).<br>References Ali, S.L., et al.: Anal. Profiles Drug Subs., 12, 73 (1983),<br></p>Fórmula:C92H4H7NO2Cor e Forma:NeatPeso molecular:169.21Dehydroxy Mirabegron Hydrochloride Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Dehydroxy Mirabegron is an impurity of Mirabegron (M364900), potent bladder relaxant and reagent for diabetes remedy. It can also be used to effectively identify impurity generated during Mirabegron synthesis, so as to control the quality.<br>References Zhang, F., et.al., Faming Zhuanli Shenqing, 15, (2014);<br></p>Fórmula:C21H24N4OS·(HCl)Cor e Forma:NeatPeso molecular:380.51 + (36.46)Etomidate
CAS:Produto Controlado<p>Applications Etomidate is a hypnotic. Neuroprotective & Neuroresearch Products<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goetz, E., et al.: Anaesthesist, 23, 331 (1974), Chang, Z. L., et al.: Anal. Profiles Drug Subs., 12, 191 (1983),<br></p>Fórmula:C14H16N2O2Cor e Forma:Off-WhitePeso molecular:244.296-Bromo-N-methylquinazolin-2-amine
CAS:Pureza:95.0%Cor e Forma:Liquid, No data available.Peso molecular:238.08799743652344Methyl 5-hydroxymethyl-1-methyl-1H-pyrazole-3-carboxylate
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:170.16799926757812Ref: 10-F316485
1gA consultar2gA consultar5gA consultar10gA consultar25gA consultar100mgA consultar250mgA consultar500mgA consultar4-fluoro-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:259.29998779296875Pentoxifylline-d6
CAS:Produto Controlado<p>Applications A labelled metabolite of Pentifylline. Methylxanthine derivative that improves blood flow by decreasing blood viscosity. Phosphodiesterase inhibitor. Inhibits the synthesis of tumor necrosis factor α (TNF-α).<br>References Ward, A., et al.: Drugs, 34, 50 (1987), Samlaska, C.P., et al.: J. Am. Acad. Dermatol., 30, 603 (1994), Poulakis, et al.: Respir. Med., 93, 52 (1999), Reuter, et al.: Am J. Physiol., 277, 854 (1999),<br></p>Fórmula:C132H6H12N4O3Cor e Forma:NeatPeso molecular:284.342-(2,6-Dimethylbenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Pureza:97.0%Peso molecular:288.3599853515625(R)-4-Hydroxy Propranolol Hydrobromide
CAS:Produto Controlado<p>Applications The main metabolite of (R)-Propranolol.<br>References Shwed, J., et al.: Xenobiotica, 22, 973 (1992), Fujita, K., et al.: Biol. Pharm. Bull., 22, 446 (1999), Walle, U., et al.: Drug Metab. Dispos., 30, 564 (2002),<br></p>Fórmula:C16H21NO3·HBrCor e Forma:NeatPeso molecular:356.25Desfluoro Ezetimibe
CAS:Produto Controlado<p>Impurity Ezetimibe Desfluoroaniline Analog (USP)<br>Stability Hygroscopic<br>Applications An impurity of the cholesterol absorption inhibitor Ezetimibe (E975000). Ezetimibe Desfluoroaniline Analog (USP).<br>References Anon.: IP.com J., 7, 4 (2007);<br></p>Fórmula:C24H22FNO3Cor e Forma:White To Off-WhitePeso molecular:391.435-Chloro-N-cyclohexylpentanamide
CAS:<p>Stability Hygroscopic<br>Applications 5-Chloro-N-cyclohexylpentanamide (cas# 15865-18-6) is a compound useful in organic synthesis.<br></p>Fórmula:C11H20ClNOCor e Forma:NeatPeso molecular:217.7364-CHLORO-2-(3-PYRIDYL)-QUINAZOLINE
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:241.679992675781253-(1H-2-INDOLYL)-4-(4-METHOXYPHENYL)-1-METHYL-1H-2-QUINOLINONE
CAS:Pureza:97.0%Peso molecular:380.4469909667969Rizatriptan
CAS:<p>Rizatriptan (Risatriptan) is a selective 5-hydroxytryptamine 1B/1D receptor agonist used in the study of migraine.</p>Fórmula:C15H19N5Pureza:99.74%Cor e Forma:SolidPeso molecular:269.35De-4-fluoro 5-Fluoro Chidamide
CAS:<p>Applications De-5-fluoro 4-Fluorochidamide is an analogue of Chidamide (CAS 743420-02-0), a hitsone deacetylase inhibitor (HDACI) that enhances gemcitabine (G305000) cytotoxicity in pancreatic cancer cells.<br>References Qiao, Z., et. al.: Biochem. Bioph. Res. Co., 434, 95 (2013)<br></p>Fórmula:C22H19FN4O2Cor e Forma:Off White PowderPeso molecular:390.413-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:318.8599853515625Cimetidine Sulfoxide
CAS:Produto Controlado<p>Impurity Cimetidine EP Impurity E<br>Applications Cimetidine Sulfoxide (Cimetidine EP Impurity E) is a metabolite of the H2-receptor antagonist Cimetidine (C441650). Cimetidine Sulfoxide is detected in the blood and urine of patients with kidney diseases.<br>References Luksa, J. et al.: J. Chrom. B Biomed. Appl., 667, 321 (1995); Lee, R.M. et al.: J. Chrom. Biomed. Appl., 146, 354 (1978);<br></p>Fórmula:C10H16N6OSCor e Forma:NeatPeso molecular:268.344-methyl-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:255.339996337890623-Methoxy-4-nitro-1H-pyrazole-5-carboxylic acid
CAS:Fórmula:C5H5N3O5Pureza:95.0%Cor e Forma:SolidPeso molecular:187.111Danofloxacin
CAS:<p>Applications Danofloxacin is a broad spectrum fluoroquinolone antibacterial compound.<br>References Golet, E., et al.: Anal. Chem., 73, 3632 (2001); Golet, E., et al.: Environ. Sci. Technol., 36, 3645 (2002); Huet, A., et al.: J. Agric. Food Chem., 54, 2822 (2006);<br></p>Fórmula:C19H20FN3O3Cor e Forma:Off-WhitePeso molecular:357.38Naloxegol Oxalate
CAS:<p>Applications Naloxegol Oxalate is an oxalate form of Naloxegol (N284470) which is a peripherally-selective opioid antagonist.<br>References Seifert, R., et al.: G Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive Activity, 227 (2012)<br></p>Fórmula:C34H53NO11•C2H2O4Cor e Forma:NeatPeso molecular:651.799003Rilpivirine
CAS:Produto Controlado<p>Applications A novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.<br>References Sun, et al.: J. Med. Chem., 41, 4648 (1998), Kashiwada, et al.: Bioorg. Med. Chem. Lett., 11, 183 (2001),<br></p>Fórmula:C22H18N6Cor e Forma:YellowPeso molecular:366.42N4-(3-Ethynylphenyl)-7-methoxyquinazoline-4,6-diamine
CAS:Pureza:95.0%Peso molecular:290.32598876953125
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