Derivados das Benzodiazepinas
As benzodiazepinas são compostos orgânicos com um núcleo bicíclico fundido de benzodiazepina, amplamente utilizadas no desenvolvimento de fármacos com propriedades ansiolíticas, sedativas, anticonvulsivantes e relaxantes musculares. Os seus derivados incluem estruturas modificadas que melhoram a seletividade e o perfil farmacocinético, permitindo a criação de novas moléculas com aplicações terapêuticas avançadas. Estes compostos são utilizados na formulação de APIs para o tratamento de distúrbios do sono, ansiedade, epilepsia e espasmos musculares. Além disso, os derivados das benzodiazepinas são essenciais na investigação de novos agentes psicotrópicos e na otimização de tratamentos neurológicos.
Na CymitQuimica, oferecemos derivados de benzodiazepinas de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e neurociência.
Foram encontrados 332 produtos de "Derivados das Benzodiazepinas"
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Brotizolam
CAS:Produto Controlado<p>Applications A hypnotic and a sedative, also used in veterinary medicine as an appetite stimulant<br>References Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Nishino, T., et al.: J. Pharmacol. Sci., 107, 349 (2008), Yamashiro, T., et al.: J. Clin. Pharm, Ther., 33, 273 (2008), Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008),<br></p>Fórmula:C15H10BrClN4SCor e Forma:WhitePeso molecular:393.69Nitrazepam
CAS:Produto Controlado<p>Applications Anticonvulsant; hypnotic.Controlled substance (depressant).<br>References Rieder, et al.: Arzneim.-Forsch., 23, 212 (1973), Kangas, L., Acta Pharmacol. Toxicol., 45, 16 (1979), Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 9, 487 (1980).<br></p>Fórmula:C15H11N3O3Cor e Forma:White To Off-WhitePeso molecular:281.273-Hydroxy Bromazepam 1.0 mg/mL in Methanol
CAS:Produto ControladoFórmula:C14H10BrN3O2Cor e Forma:ColourlessPeso molecular:332.15Clonazepam
CAS:Produto Controlado<p>Applications Antiepileptic agent with anxiolytic and antimanic properties. Anticonvulsant.This is a controlled substance (depressant).<br>References Blum, et al.: Arzneim.-Forsch., 23, 377 (1973), Winslow, W.C., et al.: Anal. Profiles Drug Subs., 6, 61 (1977)<br></p>Fórmula:C15H10ClN3O3Cor e Forma:WhitePeso molecular:315.711-Methyl-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
CAS:Pureza:98%Peso molecular:250.30099487304688Deschloro Clobazam
CAS:Produto Controlado<p>Applications Deschloro Clobazam is a metabolite of Clobazam (C582500), a benzodiazepine psychotherapeutic agent that has proven efficacy against multiple seizure types. An anxiolytic; anticonvulsant.<br>References Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990); Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Fórmula:C16H14N2O2Cor e Forma:Off WhitePeso molecular:266.29Ethyl 5-Methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate
CAS:Produto Controlado<p>Impurity Flumazenil EP Impurity E<br>Applications Ethyl 5-Methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate (Flumazenil EP Impurity E) is used in the biological studies and preparation of imidazobenzodiazepines as probes for diazepaminsensitive receptor pharmacophore.<br>References Zhang, P., et al.: J. Med. Chem., 38, 1679 (1995)<br></p>Fórmula:C15H15N3O3Cor e Forma:NeatPeso molecular:285.307-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione
CAS:Produto ControladoFórmula:C10H9FN2O2Cor e Forma:NeatPeso molecular:208.194-(2-Benzoyl-4-chlorophenyl)-5-methyl-4H-1,2,4-triazole-3-carboxaldehyde
CAS:Produto ControladoFórmula:C17H12ClN3O2Cor e Forma:NeatPeso molecular:325.758-Chloro-5,6-dihydro-5-methyl-6-oxo-4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic Acid Ethyl Ester
CAS:Produto Controlado<p>Impurity Flumazenil EP Impurity F<br>Applications 8-Chloro-5,6-dihydro-5-methyl-6-oxo-4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic Acid Ethyl Ester is an impurity of Flumazenil (F500450), an imidazodiazepine which selectively blocks the central effects of classic benzodiazepines.<br>References Hunkeler, W., et al.: Nature, 290, 514 (1981), Pole, P., et al.: Arch. Pharmacol., 316, 317 (1981), Timm, U., et al.: Arzneim.-Forsch., 33, 358 (1983),<br></p>Fórmula:C15H14ClN3O3Cor e Forma:NeatPeso molecular:319.743-AMINO-1-METHYL-5-PHENYL-1H-BENZO[E][1,4]DIAZEPIN-2(3H)-ONE
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:265.31600952148442-Bromo-acetamide-2’,5-dichlorobenzophenone
CAS:Produto Controlado<p>Stability Unstable in Solution, Moisture Sensitive<br>Applications Used in the synthesis of Cloxazolam and its metabolites.<br>References Ji, M. et al.: Zhongguo Yaoke Daxue Xuebao 24, 180 (1993); Ji, M. et al.: Zhongguo Yaoke Daxue Xuebao 25, 69 (1994).<br></p>Fórmula:C15H10BrCl2NO2Cor e Forma:NeatPeso molecular:387.067-Amino Nitrazepam
CAS:Produto Controlado<p>Applications A metabolite of Nitrazepam (N490140).<br>References Randall, L.O., et al.: Biochem. Pharmacol., 8, 15 (1961),<br></p>Fórmula:C15H13N3OCor e Forma:Light YellowPeso molecular:251.285-Nitro-2-(bromoacetamido)benzophenone
CAS:<p>Applications Nitrazepam derivative.<br>References Hagishita, S., et al.: Bioorg. Med. Chem., 5, 1433 (1997), Amblard, M., et al.: J. Med. Chem., 42, 4185 (1999), Schafferhans, A., et al.: J. Mol. Biol., 307, 407 (2001).<br></p>Fórmula:C15H11BrN2O4Cor e Forma:NeatPeso molecular:363.167-Chloro-1-methyl-5-phenyl-[1,2,4]triazolo[4,3-a]quinolin-4-amine
CAS:<p>Applications An impurity of Alprazolam (A575650). The major degradation product in Alprazolam tablets during their stability assay.<br>References Nudelman, N., et al.: J. Pharm. Sci., 91, 1274 (2002), Marin, A., et al.: Anal. Chem., 77, 471 (2005),<br></p>Fórmula:C17H13ClN4Cor e Forma:White To Off-WhitePeso molecular:308.763-Amino-6-bromo-4-(2-pyridinyl)-2(1H)-quinolinone(>90%)
CAS:Produto Controlado<p>Stability Air Sensitive<br>Applications 3-Amino-6-bromo-4-(2-pyridinyl)-2(1H)-quinolinone is an impurity of Bromazepam (B678500); a controlled substance (depressant) and anxiolytic.<br>References Schwartz, M.A., et al.: J. Pharm. Sci., 62, 1776 (1973); Chalmers, P., et al.: Anesthesia, 39, 370 (1984); Hassan, M.M., et al.: Anal. Profiles Drug Subs., 16, 1 (1987)<br></p>Fórmula:C14H10BrN3OPureza:>90%Cor e Forma:Light Brown To BrownPeso molecular:316.15(S)-Methyl 3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate
CAS:Pureza:97.0%Peso molecular:402.24798583984375Alprazolam 5-Oxide
CAS:Produto Controlado<p>Applications A metabolite of Alprazolam (A575650).<br>References Schwartz, M.A., et al.: J. Pharmacol. Exp. Ther., 149, 423 (1965), Childress, S.J., et al.: J. Pharm. Sci., 53, 577 (1964), Gall, M., et al.: J. Med. Chem., 21, 1290 (1978)<br></p>Fórmula:C17H13ClN4OCor e Forma:NeatPeso molecular:324.767-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione
CAS:Produto Controlado<p>Applications 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione (cas# 4547-02-8) is a positive allosteric modulator for the muscarinic M1 receptor, which could be a potential treament for the Alzheimer's disease or Schizophrenia.<br>References Flohr, A., et al.: Bioorg. Med. Chem. Lett., 27, 5415 (2017)<br></p>Fórmula:C15H11ClN2SCor e Forma:BeigePeso molecular:286.7792Bromazepam-d4
CAS:Produto Controlado<p>Applications Controlled substance (depressant). Anxiolytic. Labelled Bromazepam.<br>References Schwartz, M.A., et al.: J. Pharm. Sci., 62, 1776 (1973), Chalmers, P., et al.: Anesthesia, 39, 370 (1984), Hassan, M.M., et al.: Anal. Profiles Drug Subs., 16, 1 (1987),<br></p>Fórmula:C142H4H6BrN3OCor e Forma:NeatPeso molecular:320.187-methyl-5-phenyl-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one
CAS:Pureza:95.0%Peso molecular:252.31700134277344Clobazam-13C6 (1 mg/ml in Acetonitrile)
CAS:Produto ControladoFórmula:C6C10H13ClN2O2Cor e Forma:ColourlessPeso molecular:306.702-Amino-5-nitro-2'-chlorobenzophenone
CAS:<p>Impurity Clonazepam EP Impurity A<br>Applications 2-Amino-5-nitro-2'-chlorobenzophenone (Clonazepam EP Impurity A) is an impurity of Clonazepam (C587080).<br></p>Fórmula:C13H9ClN2O3Cor e Forma:NeatPeso molecular:276.68Defluoro 8-Hydroxy Flumazenil
CAS:Produto ControladoFórmula:C15H15N3O4Cor e Forma:NeatPeso molecular:301.30Flunitrazepam
CAS:Produto Controlado<p>Applications Flunitrazepam is used as an hypnotic. This is a controlled substance (depressant).<br>References Sternbach, L.H., et al.: J. Med. Chem., 6, 261 (1963), Eidelberg, E., et al.: Neurology, 5, 223 (1965), Caplan, Y., et al.: J. Anal. Toxicol., 25, 396 (2001), Wood, M., et al.: Forensic Sci. Int., 150, 227 (2005),<br></p>Fórmula:C16H12FN3O3Cor e Forma:Off-WhitePeso molecular:313.283-Amino-4-(2-chlorophenyl)-6-nitro-2(1H)-quinolinone (Clonazepam Impurity)
CAS:<p>Impurity Clonazepam EP Impurity B<br>Applications 3-Amino-4-(2-chlorophenyl)-6-nitro-2(1H)-quinolinone (Clonazepam EP Impurity B) is an impurity of Clonazepam (C587080), antiepileptic agent with anxiolytic and antimanic properties.<br>References Mayer, W., et al.: Pharmazie, 29, 700 (1974), Blum, et al.: Arzneim.-Forsch., 23, 377 (1973), Winslow, W.C., et al.: Anal. Profiles Drug Subs., 6, 61 (1977)<br></p>Fórmula:C15H10ClN3O3Cor e Forma:Yellow BrownPeso molecular:315.711-Hydroxy Alprazolam β-D-Glucuronide (>80%)
CAS:Produto ControladoFórmula:C23H21ClN4O7Pureza:>80%Cor e Forma:White SolidPeso molecular:500.897-Amino Clonazepam
CAS:Produto Controlado<p>Applications The major metabolite of Clonazepam (C587080).<br>References Clark, D., et al.: Drugs, 29, 342 (1985), Colmenero, J., et al.: Antimicrob. Agents Chemother., 38, 2798 (1994), Grant, D., et al.: Pharmacology, 61, 204 (2000), Negrusz, A., et al.: Anal. Bioanal. Chem., 376, 1198 (2003),<br></p>Fórmula:C15H12ClN3OCor e Forma:YellowPeso molecular:285.73Methyl Clonazepam
CAS:Produto Controlado<p>Applications Shows sedative and anxiolytic properties. Impairment of psychomotor performance reported. Activity blocked by flumazenil.<br>References Doumont, A., et al.: Psychopharmacology, 87, 130 (1985), Psychopharmacology, 94(4), 501 (1988)<br></p>Fórmula:C16H12ClN3O3Cor e Forma:YellowPeso molecular:329.74Alprazolam Aminomethyl Ketone Hydrochloride
CAS:Produto Controlado<p>Applications Alprazolam (A575650) impurity.<br>References Hirai, K., et al.: J. Med. Chem., 24, 20 (1981),<br></p>Fórmula:C17H16Cl2N4O·xHClCor e Forma:White To Light YellowPeso molecular:363.24Alprazolam
CAS:Produto Controlado<p>Applications Controlled substance (depressant). Anxiolytic.<br>References Sethy, V.H., et al.: Arch. Pharmacol., 301, 157 (1978), Fawcett, J.A., et al.: Pharmacotherapy, 2, 242 (1982),<br></p>Fórmula:C17H13ClN4Cor e Forma:White To Off-WhitePeso molecular:308.76Bromazepam
CAS:Produto Controlado<p>Applications Controlled substance (depressant). Anxiolytic.<br>References Schwartz, M.A., et al.: J. Pharm. Sci., 62, 1776 (1973), Chalmers, P., et al.: Anesthesia, 39, 370 (1984), Hassan, M.M., et al.: Anal. Profiles Drug Subs., 16, 1 (1987),<br></p>Fórmula:C14H10BrN3OCor e Forma:WhitePeso molecular:316.152-Amino-5-chlorobenzophenone
CAS:Produto Controlado<p>Applications A metabolite of Diazepam; but has a much weaker anticonvulsant effect.<br>References Hara, T., et al.: J. Med. Chem., 21, 263 (1978),<br></p>Fórmula:C13H10ClNOCor e Forma:YellowPeso molecular:231.68N-Desmethyl Clobazam
CAS:Produto Controlado<p>Applications N-Desmethyl Clobazam is an impurity of Clobazam (C582500), which is a benzodiazepine, psychotherapeutic agent. Clobazam (CLB) has proven efficacy against multiple seizure types and is an anxiolytic, anticonvulsant and controlled substance (depressant).<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979), Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990), Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Fórmula:C15H11ClN2O2Cor e Forma:Off-WhitePeso molecular:286.71Flumazenil Carboxylic Acid
CAS:<p>Applications Flumazenil carboxylic acid is a derivative of Flumazenil (F500450), a benzodiazepine antagonist that can prevent or abolish (at the receptor level) the effects of a benzodiazepine.<br>References Brogden, R. & Goa, K.: Drugs, 35, 448 (1988); Klotz, U. & Kanto, J.: Clin. Pharmacokinet., 14, 1 (1988)<br></p>Fórmula:C13H10FN3O3Cor e Forma:NeatPeso molecular:275.24Clobazam
CAS:Produto Controlado<p>Applications Benzodiazepine psychotherapeutic agent. Clobazam (CLB) has proven efficacy against multiple seizure types. An anxiolytic; anticonvulsant. Controlled substance (depressant).<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979), Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990), Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Fórmula:C16H13ClN2O2Cor e Forma:WhitePeso molecular:300.74Nitrazepam-d5
CAS:Produto ControladoFórmula:C152H5H6N3O3Cor e Forma:Off-White To Light YellowPeso molecular:286.303-Amino-6-chloro-4-phenylcarbostyril
CAS:<p>Applications Intermediate in the preparation of Alprazolam impurities.<br>References Hanawa, T., et al.: Drug Dev. Ind. Pharm., 26, 1199 (2000), Cheng, P., et al.: Bioorg. Med. Chem. Lett., 18, 3787 (2008),<br></p>Fórmula:C15H11ClN2OCor e Forma:NeatPeso molecular:270.71(3,4-Dimethoxyphenyl)(2-(2-hydrazonopentan-3-yl)-4,5-dimethoxyphenyl)methanone
CAS:Produto ControladoFórmula:C22H28N2O5Cor e Forma:Off WhitePeso molecular:400.477-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
CAS:Pureza:95.0%Peso molecular:315.1700134277344Flumazenil-D5
CAS:Produto Controlado<p>Applications Flumazenil-D5 is a labelled analogue of Flumazenil (F500450), a benzodiazepine antagonist that can prevent or abolish (at the receptor level) the effects of a benzodiazepine.<br>References Brogden, R. & Goa, K.: Drugs, 35, 448 (1988); Klotz, U. & Kanto, J.: Clin. Pharmacokinet., 14, 1 (1988)<br></p>Fórmula:C15H9D5FN3O3Cor e Forma:NeatPeso molecular:303.295-Chloro-2-(3-methyl-4H-1,2,4-triazol-4-yl)benzophenone
CAS:<p>Applications An impurity of Alprazolam (A575650).<br>References Cho, M., et al.: J. Med. Chem., 29, 1346 (1986), Hall, M., et al.: J. Anal. Toxicol., 19, 511 (1995), Nudelman, N., et al.: J. Pharm. Sci., 84, 998 (1995), Yuan, R., et al.: J. Clin. Pharmacol., 39, 1109 (1999),<br></p>Fórmula:C16H12ClN3OCor e Forma:NeatPeso molecular:297.74Clonazepam-13C2 ,15N
CAS:Produto Controlado<p>Applications Clonazepam-13C2 ,15N, is the labeled analogue of Clonazepam (C587080), an antiepileptic agent with anxiolytic and antimanic properties.<br>References Blum, et al.: Arzneim.-Forsch., 23, 377 (1973), Winslow, W.C., et al.: Anal. Profiles Drug Subs., 6, 61 (1977)<br></p>Fórmula:C1313C2H10ClN215NO3Cor e Forma:NeatPeso molecular:318.69Nor-Flunitrazepam
CAS:Produto Controlado<p>Applications A metabolite of Flunitrazepam (F500700).<br>References Asai, H., et al.: J. Pharmacol. Exp. Ther., 277, 1004 (1996), Kilicarslan, T., et al.: Drug Metab. Dispos., 29, 460 (2001), Tanaka, E., et al.: J. Toxicol. Clin. Toxicol., 40, 69 (2002),<br></p>Fórmula:C15H10FN3O3Cor e Forma:YellowPeso molecular:299.263-Amino-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one
CAS:Pureza:95.0%Peso molecular:251.28900146484375N-Desmethyl Clobazam-13C6
CAS:Produto Controlado<p>Applications N-Desmethyl Clobazam-13C6 is an isotope labelled metabolite of Clobazam (C582500), a benzodiazepine psychotherapeutic agent that has proven efficacy against multiple seizure types.<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979); Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990); Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Fórmula:C913C6H11ClN2O2Cor e Forma:Off-WhitePeso molecular:292.6695-Chloro-2-(3-chloromethyl-4H-1,2,4-triazol-4-yl)-benzophenone
CAS:Produto Controlado<p>Applications 5-Chloro-2-(3-chloromethyl-4H-1,2,4-triazol-4-yl)-benzophenone is an impurity in the synthesis of Estazolam (E668380), a benzodiazepine derivative possessing anxiolytic, anticonvulsant, and muscle relaxant properties. It is commonly prescribed to treat short-term insomnia.<br>References Barroso, M., et al.: Anal. Bioanal. Chem., 396, 3059 (2010), Rodgers, A., et al.: Chem. Res., Toxicol., 23, 724 (2010), Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010),<br></p>Fórmula:C16H11Cl2N3OCor e Forma:NeatPeso molecular:332.18Cloxazolam
CAS:Produto Controlado<p>Applications Cloxazolam is a benzodiazepine derivative with anxiolytic, hypnotic and antihypertensive properties used as an anti-anxiety drug. It is metabolized into the active metabolite Delorezepam (D230675). Controlled Substance.<br>References Oliveira-Silva, D. et al.: Biomed. Chrom., 23, 1266 (2009); Kamioka, T. et al.: Psychopharmacol., 52, 17 (1977); Fischer-Cornelssen, K.A. et al.: Arzneim.-Forsch., 31, 1757 (1981);<br></p>Fórmula:C17H14Cl2N2O2Cor e Forma:NeatPeso molecular:349.212-Bromo-N-[2-(2-chlorobenzoyl)-4-nitrophenyl]acetamide(Clonazepam Impurity)
CAS:Produto Controlado<p>Applications An impurity from the synthesis of clonazepam (C587080)<br></p>Fórmula:C15H10BrClN2O4Cor e Forma:Light YellowPeso molecular:397.613-Hydroxy Bromazepam-d4
CAS:Produto Controlado<p>Applications Major metabolite of labelled Bromazepam (B678502)<br>References Musshoff, F., et al.: Clin. Chem. Lab. Med., 36, 803 (1998), El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001), Darzy, K., et al.: Clin. Endocrinol., 70, 287 (2009),<br></p>Fórmula:C14H6D4BrN3O2Cor e Forma:Light YellowPeso molecular:336.18Clonazepam-d4
CAS:Produto Controlado<p>Applications Labelled Clonazepam (C587080). Antiepileptic agent with anxiolytic and antimanic properties. Anticonvulsant.This is a controlled substance (depressant).<br>References Blum, et al.: Arzneim.-Forsch., 23, 377 (1973), Winslow, W.C., et al.: Anal. Profiles Drug Subs., 6, 61 (1977)<br></p>Fórmula:C152H4H6ClN3O3Cor e Forma:Yellow To Dark YellowPeso molecular:319.74N-Desmethyl Clobazam-d5
CAS:Produto Controlado<p>Applications The major labelled metabolite of Clobazam (C582500). Controlled substance (depressant).<br>References Bardy, A., et al.: Brain Develop., 13, 174 (1991), Patsalos, P., et al.: Epilepsia, 43, 365 (2002), Venisse, N., et al.: J. Anal. Toxicol., 27, 7 (2003),<br></p>Fórmula:C152H5H6ClN2O2Cor e Forma:Off-WhitePeso molecular:291.74Flumazenil
CAS:Produto Controlado<p>Applications Flumazenil is an imidazodiazepine which selectively blocks the central effects of classic benzodiazepines. It is used as benzodiazepine antagonist.<br>References Hunkeler, W., et al.: Nature, 290, 514 (1981), Pole, P., et al.: Arch. Pharmacol., 316, 317 (1981), Timm, U., et al.: Arzneim.-Forsch., 33, 358 (1983),<br></p>Fórmula:C15H14FN3O3Cor e Forma:Off WhitePeso molecular:303.293-Amino-6-nitro-4-phenyl-2(H)-quinolinone
CAS:Produto ControladoFórmula:C15H11N3O3Cor e Forma:OrangePeso molecular:281.272-(2-Amino-5-bromobenzoyl)pyridine
CAS:<p>Impurity Bromazepam EP impurity A<br>Applications Intermediate in the preparation of Bromazepam.<br>References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998), El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001), Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005),<br></p>Fórmula:C12H9BrN2OCor e Forma:Light Yellow To YellowPeso molecular:277.122H-1,4-Benzodiazepin-2-one, 3-amino-1,3-dihydro-5-phenyl-, (3S)-
CAS:Pureza:98%Peso molecular:251.289Clobazam-d5
CAS:Produto Controlado<p>Applications Labelled Clobazam (C582500). Benzodiazepine psychotherapeutic agent. Clobazam (CLB) has proven efficacy against multiple seizure types. An anxiolytic; anticonvulsant. Controlled substance (depressant).<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979), Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990), Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993),<br></p>Fórmula:C16H8D5ClN2O2Cor e Forma:Off White PowderPeso molecular:305.772-[3-(Hydroxymethyl)-5-methyl-4-triazolyl]-5-chlorobenzophenone
CAS:<p>Applications An impurity of Alprazolam (A575650).<br>References Nudelman, N., et al.: J. Pharm. Sci., 91, 1274 (2002), Marin, A., et al.: Anal. Chem., 77, 471 (2005),<br></p>Fórmula:C17H14ClN3O2Cor e Forma:Off White SolidPeso molecular:327.76Alprazolam-d3
CAS:Produto Controlado<p>Applications Controlled substance (depressant). Anxiolytic.<br>References Sethy, V.H., et al.: Arch. Pharmacol., 301, 157 (1978), Fawcett, J.A., et al.: Pharmacotherapy, 2, 242 (1982),<br></p>Fórmula:C17H10ClD3N4Cor e Forma:NeatPeso molecular:311.806-Chloro-2,3-dimethyl-1-phenyl-1H-benzo[d]imidazol-3-ium Chloride
CAS:<p>Applications 6-Chloro-2,3-dimethyl-1-phenyl-1H-benzo[d]imidazol-3-ium Chloride is a degradation product of Clobazam (C582500), a benzodiazepine psychotherapeutic agent that has proven efficacy against multiple seizure types. An anxiolytic; anticonvulsant.<br>References Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990); Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Fórmula:C15H14ClN2·ClCor e Forma:NeatPeso molecular:293.191(R)-3-amino-9-fluoro-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one
Pureza:97%Peso molecular:269.27899169921875Clobazam-13C6
CAS:Produto Controlado<p>Applications Clobazam-13C6 is the isotope labelled analog of Clobazam (C582500); a benzodiazepine psychotherapeutic agent. Clobazam (CLB) has proven efficacy against multiple seizure types. An anxiolytic and anticonvulsant. Controlled substance (depressant).<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979); Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990); Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Fórmula:C6C10H13ClN2O2Cor e Forma:Off-WhitePeso molecular:306.707-Acetamido Clonazepam
CAS:Produto Controlado<p>Applications Clonazepam (C587080) metabolite.<br>References Huang, W., et al.: J. Anal. Toxicol., 19, 333 (1995), Rittner, M., et al.: J. Anal. Toxicol., 25, 115 (2001),<br></p>Fórmula:C17H14ClN3O2Cor e Forma:NeatPeso molecular:327.76Clobazam impurity D
<p>Clobazam impurity D is a natural metabolite of clobazam. It is a white crystalline solid that is soluble in methanol, ethanol, and dichloromethane. Clobazam impurity D has been shown to be an analytical standard for HPLC analysis. It has also been used as a reference material for the pharmacopoeia, which is a publication that sets standards for purity or strength of chemicals and drugs. Clobazam impurity D is synthesized by the reaction of 3-chloro-2-(2-oxopyrrolidin-1-yl)benzamide with N,N-dimethylformamide dimethyl acetal.</p>Fórmula:C18H17ClN2O2Pureza:Min. 95%Peso molecular:328.79 g/mol4-Boc-8-Fluoro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C14H19FN2O2Pureza:98%Cor e Forma:SolidPeso molecular:266.3167-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C9H11ClN2Pureza:95%Cor e Forma:SolidPeso molecular:182.65Tert-butyl 2,3,4,5-tetrahydro-1h-benzo[e][1,4]diazepine-1-carboxylate
CAS:Pureza:95%Peso molecular:248.3260047-Chloro-1-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Pureza:98%Peso molecular:224.63999944-Boc-7-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C14H19ClN2O2Pureza:97%Peso molecular:282.777-methoxy-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Pureza:98%Peso molecular:220.22799683-(Piperidin-4-yl)-1,3,4,5-tetrahydro-2H-benzo[d][1,3]diazepin-2-one
CAS:Pureza:97%Peso molecular:245.3260048-Fluoro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C9H11FN2Pureza:97.0%Peso molecular:166.1997-Amino-4-Boc-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C14H21N3O2Pureza:95%Peso molecular:263.3419-amino-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-5-one
CAS:Fórmula:C9H11N3OPureza:95%Peso molecular:177.2071-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Fórmula:C10H10N2O2Pureza:95.0%Cor e Forma:SolidPeso molecular:190.2022,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepin-7-ol
CAS:Fórmula:C9H12N2OPureza:97.0%Peso molecular:164.2088-Amino-4-Boc-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C14H21N3O2Pureza:97%Peso molecular:263.3414-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione
CAS:Fórmula:C10H10N2O2Pureza:95.0%Peso molecular:190.2027-Fluoro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C9H11FN2Pureza:95%Cor e Forma:SolidPeso molecular:166.1994-Boc-7-Fluoro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C14H19FN2O2Pureza:97.0%Cor e Forma:SolidPeso molecular:266.3167-Bromo-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Fórmula:C9H7BrN2O2Pureza:97%Cor e Forma:SolidPeso molecular:255.0717-Bromo-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Pureza:95+%Peso molecular:269.09799193,4-Dihydro-1H-1,4-benzodiazepine-2,5-dione
CAS:Fórmula:C9H8N2O2Pureza:98%Cor e Forma:SolidPeso molecular:176.1754-Boc-7-Bromo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C14H19BrN2O2Pureza:97.0%Cor e Forma:SolidPeso molecular:327.2229-Nitro-3,4-dihydro-1H-benzo[e][1,4]diazepin-5(2H)-one
CAS:Fórmula:C9H9N3O3Pureza:95.0%Peso molecular:207.1897-Fluoro-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Fórmula:C9H7FN2O2Pureza:97.0%Cor e Forma:SolidPeso molecular:194.1654-Boc-2,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C14H20N2O2Pureza:97.0%Cor e Forma:SolidPeso molecular:248.3264-Boc-9-Methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C15H22N2O2Pureza:97.0%Peso molecular:262.3534-Boc-7-Methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C15H22N2O2Pureza:97.0%Peso molecular:262.3532,3,4,5-TETRAHYDRO-1H-BENZO[E][1,4]DIAZEPIN-8-YLAMINE 2HCL
CAS:Fórmula:C9H15Cl2N3Pureza:97.0%Peso molecular:236.149-Methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C10H14N2Pureza:97.0%Peso molecular:162.2364-Boc-9-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C14H19ClN2O2Pureza:97.0%Peso molecular:282.779-CHLORO-3,4-DIHYDRO-1H-BENZO[E][1,4]DIAZEPINE-2,5-DIONE
CAS:Fórmula:C9H7ClN2O2Pureza:97.0%Peso molecular:210.628-Chloro-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Fórmula:C9H7ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:210.624-Boc-8-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C14H19ClN2O2Pureza:97.0%Peso molecular:282.777,8-Dimethoxy-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C11H16N2O2Pureza:97.0%Peso molecular:208.2617-BROMO-2,3,4,5-TETRAHYDRO-1H-BENZO[E][1,4]DIAZEPINE HCL
CAS:Fórmula:C9H12BrClN2Pureza:95.0%Peso molecular:263.568-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C9H11ClN2Pureza:97.0%Cor e Forma:SolidPeso molecular:182.652,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C9H12N2Pureza:97.0%Cor e Forma:White to yellow/orange crystalline powderPeso molecular:148.2098-Bromo-3,4-dihydro-1H-benzo[e][1,4]diazepin-5(2H)-one
CAS:Fórmula:C9H9BrN2OPureza:97.0%Peso molecular:241.0884-Boc-7,8-Dimethoxy-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C16H24N2O4Pureza:97.0%Peso molecular:308.3787-Methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C10H14N2Pureza:97.0%Cor e Forma:SolidPeso molecular:162.2364-Boc-7-Hydroxy-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Fórmula:C14H20N2O3Pureza:97.0%Peso molecular:264.3251,2,4,5-Tetrahydro-benzo[e][1,4]diazepin-3-one
CAS:Fórmula:C9H10N2OPureza:97.0%Cor e Forma:SolidPeso molecular:162.1927-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione
CAS:Fórmula:C10H9FN2O2Pureza:97%Peso molecular:208.1927-AMINO-4-BOC-4,5-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-2(3H)-ONE
CAS:Fórmula:C14H19N3O3Pureza:97.0%Peso molecular:277.3242-(2-Aminoacetamido)-5-nitro-2'-chlorobenzophenone Hydrochloride (Clonazepam Impurity)
CAS:Produto ControladoFórmula:C15H12ClN3O4·ClHCor e Forma:WhitePeso molecular:370.1874N,N-Dimethylformamide Diethyl Acetal
CAS:Produto Controlado<p>Stability Moisture Sensitive<br>Applications N,N-Dimethylformamide Diethyl Acetal is used as a reagent in the design of EGF-R tyrosine kinase inhibitors. Also used in the synthesis of aminopyridine derivatives.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Traxler, P. et al.: J. Med. Chem., 40, 3601 (1997); Cheikh, N. et al.: Tetrahedron, 69, 1234 (2013);<br></p>Fórmula:C7H17NO2Cor e Forma:NeatPeso molecular:147.223-Amino-4-(2-fluorophenyl)-1-methyl-6-nitroquinolin-2(1H)-one
CAS:Produto ControladoFórmula:C16H12FN3O3Cor e Forma:NeatPeso molecular:313.28N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide
CAS:Produto Controlado<p>Applications N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500).<br>References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)<br></p>Fórmula:C14H10BrClN2O2Cor e Forma:Light Yellow To BeigePeso molecular:353.602-Bromo-N-[4-bromo-2-(2-pyridinylcarbonyl)phenyl]-acetamide
CAS:Produto Controlado<p>Applications 2-Bromo-N-[4-bromo-2-(2-pyridinylcarbonyl)phenyl]-acetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500).<br>References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)<br></p>Fórmula:C14H10Br2N2O2Cor e Forma:NeatPeso molecular:398.05Alprazolam 5,6-Epoxide
CAS:Produto Controlado<p>Applications Alprazolam derivative.<br>References Hester, J. et al., J. of Med. Chem. 23, 643 (1980)<br></p>Fórmula:C17H13ClN4OCor e Forma:NeatPeso molecular:324.773-Amino-6-chloro-3,4-dihydro-2-methyl-4-phenyl-4-quinazolinol
CAS:Produto ControladoFórmula:C15H14ClN3OCor e Forma:NeatPeso molecular:287.742-Amino-5-nitrobenzophenone
CAS:Produto ControladoFórmula:C13H10N2O3Cor e Forma:NeatPeso molecular:242.23Flumazenil Carboxylic Acid-D3
Produto Controlado<p>Applications Flumazenil Carboxylic Acid-D3 is an isotope labelled form of Flumazenil Carboxylic Acid (F500455); a derivative of Flumazenil (F500455), a benzodiazepine antagonist that can prevent or abolish (at the receptor level) the effects of a benzodiazepine.<br>References Brogden, R. & Goa, K.: Drugs, 35, 448 (1988); Klotz, U. & Kanto, J.: Clin. Pharmacokinet., 14, 1 (1988)<br></p>Fórmula:C13H7D3FN3O3Cor e Forma:NeatPeso molecular:278.257-Aminonorflunitrazepam
CAS:Produto ControladoFórmula:C15H12FN3OCor e Forma:Light YellowPeso molecular:269.272-(2-Acetylhydrazino)-7-chloro-5-phenyl-3H-1,4-benzodiazepine
CAS:Produto Controlado<p>Applications 2-(2-Acetylhydrazino)-7-chloro-5-phenyl-3H-1,4-benzodiazepine is an impurity of Alprazolam (A575650.<br>References Hester, J.B., et al.: J. Org. Chem., 44, 2688, (1979); Anjaneyulu, Y., et al.: Asian. J. Chem., 19, 3375 (2007);<br></p>Fórmula:C17H15ClN4OCor e Forma:White To Off-WhitePeso molecular:326.783-Methyl Clobazam
CAS:Produto Controlado<p>Applications 3-Methyl Clobazam is a metabolite of Clobazam (C582500), a benzodiazepine psychotherapeutic agent that has proven efficacy against multiple seizure types. An anxiolytic; anticonvulsant.<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979); Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990); Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Fórmula:C17H15ClN2O2Cor e Forma:NeatPeso molecular:314.77Clobazam CIV
CAS:Produto Controlado<p>Clobazam (inn) and methyprylon (inn)</p>Fórmula:C16H13ClN2O2Cor e Forma:White Crystalline PowderPeso molecular:300.066562-(2-Amino-5-bromobenzoyl)pyridine
CAS:<p>2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval</p>Fórmula:C12H9BrN2OPureza:Min. 95%Peso molecular:277.12 g/molRef: 4Z-E-153009
Produto descontinuadoRef: 4Z-A-231026
Produto descontinuado7-Amino Clonazepam-d4
CAS:Produto Controlado<p>Applications A labelled major metabolite of Clonazepam (C587080).<br>References Clark, D., et al.: Drugs, 29, 342 (1985), Colmenero, J., et al.: Antimicrob. Agents Chemother., 38, 2798 (1994), Grant, D., et al.: Pharmacology, 61, 204 (2000), Negrusz, A., et al.: Anal. Bioanal. Chem., 376, 1198 (2003),<br></p>Fórmula:C152H4H8ClN3OCor e Forma:NeatPeso molecular:289.75
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