Derivados das Benzodiazepinas
As benzodiazepinas são compostos orgânicos com um núcleo bicíclico fundido de benzodiazepina, amplamente utilizadas no desenvolvimento de fármacos com propriedades ansiolíticas, sedativas, anticonvulsivantes e relaxantes musculares. Os seus derivados incluem estruturas modificadas que melhoram a seletividade e o perfil farmacocinético, permitindo a criação de novas moléculas com aplicações terapêuticas avançadas. Estes compostos são utilizados na formulação de APIs para o tratamento de distúrbios do sono, ansiedade, epilepsia e espasmos musculares. Além disso, os derivados das benzodiazepinas são essenciais na investigação de novos agentes psicotrópicos e na otimização de tratamentos neurológicos.
Na CymitQuimica, oferecemos derivados de benzodiazepinas de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e neurociência.
Foram encontrados 332 produtos de "Derivados das Benzodiazepinas"
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(S)-Methyl 3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate
CAS:Pureza:97.0%Peso molecular:402.24798583984375Alprazolam 5-Oxide
CAS:Produto Controlado<p>Applications A metabolite of Alprazolam (A575650).<br>References Schwartz, M.A., et al.: J. Pharmacol. Exp. Ther., 149, 423 (1965), Childress, S.J., et al.: J. Pharm. Sci., 53, 577 (1964), Gall, M., et al.: J. Med. Chem., 21, 1290 (1978)<br></p>Fórmula:C17H13ClN4OCor e Forma:NeatPeso molecular:324.767-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione
CAS:Produto Controlado<p>Applications 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione (cas# 4547-02-8) is a positive allosteric modulator for the muscarinic M1 receptor, which could be a potential treament for the Alzheimer's disease or Schizophrenia.<br>References Flohr, A., et al.: Bioorg. Med. Chem. Lett., 27, 5415 (2017)<br></p>Fórmula:C15H11ClN2SCor e Forma:BeigePeso molecular:286.7792Bromazepam-d4
CAS:Produto Controlado<p>Applications Controlled substance (depressant). Anxiolytic. Labelled Bromazepam.<br>References Schwartz, M.A., et al.: J. Pharm. Sci., 62, 1776 (1973), Chalmers, P., et al.: Anesthesia, 39, 370 (1984), Hassan, M.M., et al.: Anal. Profiles Drug Subs., 16, 1 (1987),<br></p>Fórmula:C142H4H6BrN3OCor e Forma:NeatPeso molecular:320.187-methyl-5-phenyl-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one
CAS:Pureza:95.0%Peso molecular:252.31700134277344Clobazam-13C6 (1 mg/ml in Acetonitrile)
CAS:Produto ControladoFórmula:C6C10H13ClN2O2Cor e Forma:ColourlessPeso molecular:306.702-Amino-5-nitro-2'-chlorobenzophenone
CAS:<p>Impurity Clonazepam EP Impurity A<br>Applications 2-Amino-5-nitro-2'-chlorobenzophenone (Clonazepam EP Impurity A) is an impurity of Clonazepam (C587080).<br></p>Fórmula:C13H9ClN2O3Cor e Forma:NeatPeso molecular:276.68Defluoro 8-Hydroxy Flumazenil
CAS:Produto ControladoFórmula:C15H15N3O4Cor e Forma:NeatPeso molecular:301.30Flunitrazepam
CAS:Produto Controlado<p>Applications Flunitrazepam is used as an hypnotic. This is a controlled substance (depressant).<br>References Sternbach, L.H., et al.: J. Med. Chem., 6, 261 (1963), Eidelberg, E., et al.: Neurology, 5, 223 (1965), Caplan, Y., et al.: J. Anal. Toxicol., 25, 396 (2001), Wood, M., et al.: Forensic Sci. Int., 150, 227 (2005),<br></p>Fórmula:C16H12FN3O3Cor e Forma:Off-WhitePeso molecular:313.283-Amino-4-(2-chlorophenyl)-6-nitro-2(1H)-quinolinone (Clonazepam Impurity)
CAS:<p>Impurity Clonazepam EP Impurity B<br>Applications 3-Amino-4-(2-chlorophenyl)-6-nitro-2(1H)-quinolinone (Clonazepam EP Impurity B) is an impurity of Clonazepam (C587080), antiepileptic agent with anxiolytic and antimanic properties.<br>References Mayer, W., et al.: Pharmazie, 29, 700 (1974), Blum, et al.: Arzneim.-Forsch., 23, 377 (1973), Winslow, W.C., et al.: Anal. Profiles Drug Subs., 6, 61 (1977)<br></p>Fórmula:C15H10ClN3O3Cor e Forma:Yellow BrownPeso molecular:315.711-Hydroxy Alprazolam β-D-Glucuronide (>80%)
CAS:Produto ControladoFórmula:C23H21ClN4O7Pureza:>80%Cor e Forma:White SolidPeso molecular:500.897-Amino Clonazepam
CAS:Produto Controlado<p>Applications The major metabolite of Clonazepam (C587080).<br>References Clark, D., et al.: Drugs, 29, 342 (1985), Colmenero, J., et al.: Antimicrob. Agents Chemother., 38, 2798 (1994), Grant, D., et al.: Pharmacology, 61, 204 (2000), Negrusz, A., et al.: Anal. Bioanal. Chem., 376, 1198 (2003),<br></p>Fórmula:C15H12ClN3OCor e Forma:YellowPeso molecular:285.73Methyl Clonazepam
CAS:Produto Controlado<p>Applications Shows sedative and anxiolytic properties. Impairment of psychomotor performance reported. Activity blocked by flumazenil.<br>References Doumont, A., et al.: Psychopharmacology, 87, 130 (1985), Psychopharmacology, 94(4), 501 (1988)<br></p>Fórmula:C16H12ClN3O3Cor e Forma:YellowPeso molecular:329.74Alprazolam Aminomethyl Ketone Hydrochloride
CAS:Produto Controlado<p>Applications Alprazolam (A575650) impurity.<br>References Hirai, K., et al.: J. Med. Chem., 24, 20 (1981),<br></p>Fórmula:C17H16Cl2N4O·xHClCor e Forma:White To Light YellowPeso molecular:363.24Alprazolam
CAS:Produto Controlado<p>Applications Controlled substance (depressant). Anxiolytic.<br>References Sethy, V.H., et al.: Arch. Pharmacol., 301, 157 (1978), Fawcett, J.A., et al.: Pharmacotherapy, 2, 242 (1982),<br></p>Fórmula:C17H13ClN4Cor e Forma:White To Off-WhitePeso molecular:308.76Bromazepam
CAS:Produto Controlado<p>Applications Controlled substance (depressant). Anxiolytic.<br>References Schwartz, M.A., et al.: J. Pharm. Sci., 62, 1776 (1973), Chalmers, P., et al.: Anesthesia, 39, 370 (1984), Hassan, M.M., et al.: Anal. Profiles Drug Subs., 16, 1 (1987),<br></p>Fórmula:C14H10BrN3OCor e Forma:WhitePeso molecular:316.152-Amino-5-chlorobenzophenone
CAS:Produto Controlado<p>Applications A metabolite of Diazepam; but has a much weaker anticonvulsant effect.<br>References Hara, T., et al.: J. Med. Chem., 21, 263 (1978),<br></p>Fórmula:C13H10ClNOCor e Forma:YellowPeso molecular:231.68N-Desmethyl Clobazam
CAS:Produto Controlado<p>Applications N-Desmethyl Clobazam is an impurity of Clobazam (C582500), which is a benzodiazepine, psychotherapeutic agent. Clobazam (CLB) has proven efficacy against multiple seizure types and is an anxiolytic, anticonvulsant and controlled substance (depressant).<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979), Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990), Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Fórmula:C15H11ClN2O2Cor e Forma:Off-WhitePeso molecular:286.71Flumazenil Carboxylic Acid
CAS:<p>Applications Flumazenil carboxylic acid is a derivative of Flumazenil (F500450), a benzodiazepine antagonist that can prevent or abolish (at the receptor level) the effects of a benzodiazepine.<br>References Brogden, R. & Goa, K.: Drugs, 35, 448 (1988); Klotz, U. & Kanto, J.: Clin. Pharmacokinet., 14, 1 (1988)<br></p>Fórmula:C13H10FN3O3Cor e Forma:NeatPeso molecular:275.24Clobazam
CAS:Produto Controlado<p>Applications Benzodiazepine psychotherapeutic agent. Clobazam (CLB) has proven efficacy against multiple seizure types. An anxiolytic; anticonvulsant. Controlled substance (depressant).<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979), Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990), Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Fórmula:C16H13ClN2O2Cor e Forma:WhitePeso molecular:300.74
![(S)-Methyl 3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF546127.webp&w=3840&q=75)
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