Esteroides e Derivados
Os esteroides são compostos orgânicos que possuem uma estrutura de quatro anéis fundidos, conhecida como núcleo esteroide. Esse núcleo pode estar ligado a vários grupos funcionais que modificam suas propriedades e funções biológicas. Os esteroides desempenham um papel fundamental na regulação dos processos metabólicos e hormonais. São utilizados na medicina para tratar distúrbios inflamatórios, doenças autoimunes e desequilíbrios hormonais. Além disso, alguns derivados de esteroides possuem potentes propriedades anti-inflamatórias, como os corticosteroides. Em terapias específicas, são utilizados para reduzir a inflamação e controlar a dor em diversas doenças.
Na CymitQuimica, oferecemos uma variedade de esteroides e seus derivados para pesquisa e desenvolvimento farmacêutico.
Foram encontrados 4948 produtos de "Esteroides e Derivados"
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7α-Thiomethyl Spironolactone-d7 (Major)
CAS:Produto Controlado<p>Applications A labelled metabolite of Spironolactone.<br>References Gochman, N., et al.: J. Pharmacol. Exp. Ther., 135, 312 (1962), Tori, K., et al.: Steroids, 4, 713 (1964), Solymoss, B., et al.: Toxicol. Appli. Pharmacol., 18, 586 (1971),<br></p>Fórmula:C23H25D7O3SCor e Forma:NeatPeso molecular:395.61(3α)-Allopregnanolone-d5
CAS:Produto Controlado<p>Applications Labelled (3α)-Allopregnanolone. (3α)-Allopregnanolone acts as a GABAA receptor positive allosteric modulator. (3α)-Allopregnanolone is a metabolite of Progesterone (P755900). (3α)-Allopregnanolone is a neuroactive steroid present in the blood and also the brain.<br>References Puja, G. et al.: Neuron, 4, 759 (1990); Belelli, D. et ael. Neurosteroid, 6, 565 (2006); Viapiano, M. et al.: Neurochem. Res., 23, 155 (1998);<br></p>Fórmula:C21H29D5O2Cor e Forma:NeatPeso molecular:323.52Tachysterol (>90%)
CAS:<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Bioactive, synthetic vitamin D3 analog; exhibits antiproliferative effect on keratinocytes. Antipsoriatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Matsunaga, T., et al.: J. Dermatol., 17, 135 (1990), Gerritsen, M.J.P., et al.: Br. J. Dermatol., 131, 57 (1994),<br></p>Fórmula:C28H44OPureza:>90%Cor e Forma:NeatPeso molecular:396.65Gestrinone
CAS:Produto Controlado<p>Applications Gestrinone is a Steroidal antiestrogen, antiprogestogen, analog of Norgestrienone. Antigonadotropin.Controlled substance.<br>References Azadian-Boulanger, G., et al.: Am. J. Obstet. Gynecol., 125, 1049 (1976), Thomas, E.J., et al.: Br. Med. J., 294, 272 (1987), Coutinho, E.M., et al.: Fertil. Steril., 49, 418 (1988),<br></p>Fórmula:C21H24O2Cor e Forma:NeatPeso molecular:308.40Androst-4-ene-3,6,17-trione
CAS:Produto Controlado<p>Applications An aromatase inhibitor.<br>References Aello, A., et al.: J. Nat. Prod., 54, 281 (1991), Salaja, B.A., et al.: Steroids, 59, 330 (1994), Hunter, A.C., et al.: J. Steroid Biochem. Mol. Biol., 87, 301 (2003),<br></p>Fórmula:C19H24O3Cor e Forma:NeatPeso molecular:300.39Cortisol-9,11,12,12-d4
CAS:Produto Controlado<p>Applications Labelled Cortisol (H714615). Cortisol, or Hydrocortisone, is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.<br>References Hechter, O., et al.: Arch. Biochem. Biophys., 25, 457 (1950), Colingsworth, D.R., et al.: J. Biol. Chem., 203, 807 (1953), Florey, K., et al.: Anal. Profiles Drug Subs., 12, 277 (1983),<br></p>Fórmula:C212H4H26O5Cor e Forma:Off-WhitePeso molecular:366.48Estrone
CAS:Produto Controlado<p>Impurity Estradiol EP Impurity A/ Ethinylestradiol EP Impurity C<br>Applications Estrone is a metabolite of 17β-Estradiol (E888000). During the metabolism, it is in rapid equilibrium with Estriol (E888960) and 17β-Estradiol (E888000) (1). Causes the feminization of male fish at human and animal waste sites (2).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Both, D. et al.: Anal. Prof. Drug Subst. 1983 12 pp135-1892. Goodman-Gruen, D. et al.: J. Clin. Endocrinol. Metab. 1996 Aug;81(8):2999-3003.<br></p>Fórmula:C18H22O2Cor e Forma:White To Off-WhitePeso molecular:270.37Norgestrel-d6 (Major)
CAS:Produto Controlado<p>Applications Labelled Norgestrel. It is an excellent progestational and ovulation inhibiting steroid. The bioactive enantiomer is levorotatory. Progestogen; oral contraceptive.<br>References Sopirak, A.M., et al.: Anal. Profiles Drug Subs., 4, 294 (1975), Dunson, T.R., et al.: Contraception, 48, 109 (1993),<br></p>Fórmula:C21H22D6O2Cor e Forma:White To Light YellowPeso molecular:318.49(-)-Estra-4,9-diene-3,17-dione
CAS:Produto Controlado<p>Applications A potential metabolite of STS 557 (Dienogest)(D441870). A steroid with antiglucocorticoid activity.<br>References Kloosterboer, H., et al.: J. Steroid Biochem., 31, 567 (1988),<br></p>Fórmula:C18H22O2Cor e Forma:NeatPeso molecular:270.374-Hydroxyestradiol 4-O-β-D-Glucuronide Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-Hydroxyestradiol 4-O-β-D-Glucuronide Sodium Salt, is a glucuronide derivative of 4-Hydroxy-17β-estradiol (H941895); a metabolite of Estradiol (E888000) which is the major estrogen secreted by the premenopausal ovary.<br>References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985); Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991); Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998); Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000); Salole, E.G., et al.: Anal. Profiles Drug Subs., 15, 283 (1986); Lievertz, R.W., et al.: Am. J. Obstet. Gynecol., 156, 1289 (1987)<br></p>Fórmula:C24H32O9•xNaCor e Forma:NeatPeso molecular:464.5116α-Homo 2-(Hydroxymethyl)betamethasone
CAS:Produto ControladoFórmula:C22H29FO5Cor e Forma:NeatPeso molecular:392.4617α-Hydroxy Cholesterol
CAS:Produto Controlado<p>Applications Secondary metabolite of Cholesterol.<br>References Notaro, G., et al.: J. Nat. Prod., 55, 1588 (1992), Aydogmus, Z., et al.: Nat. Prod. Res., 18, 43 (2004), Mao, S., et al.: J. Nat. Prod ., 69, 1209 (2006), Shoji, T., et al.: J. Agric. Food Chem., 54, 884 (2006),<br></p>Fórmula:C27H46O2Cor e Forma:Off-WhitePeso molecular:402.655-β-Pregnane-3-α,20-α-diol
CAS:<p>Applications 5β-Pregnane-3α,20α-diol is a metabolite of Progesterone (P755900).<br>References Beall, et al.: Biochem. J., 31, 35 (1937), Okuda, A., et al.: J. Biol. Chem., 259, 7519 (1984), Russell, D., et al.: Biochemistry, 31, 4737 (1992), Kondo, K., et al.: Eur. J. Biochem., 219, 357 (1994), Westerbacka, J., et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003),<br></p>Fórmula:C21H36O2Cor e Forma:White To Off-WhitePeso molecular:320.51(6a,11b,16b)-6-Bromo-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:<p>Applications (6α,11β,16β)-6-Bromo-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione is a derivative of Betamethasone (B327000), a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),<br></p>Fórmula:C22H28BrFO5Cor e Forma:NeatPeso molecular:471.36Dihydro Finasteride
CAS:<p>Impurity Finasteride EP Impurity A<br>Applications Dihydro Finasteride (Finasteride EP Impurity A) is the reduced product of Finasteride (F342000): a mechanism-based inhibitor of human prostate and skin steroid 5α-reductase. It forms an enzyme-bound NADP-dihydrofinasteride adduct during this inhibitory process.<br>References Bull, H.G. et al.: Am. J. Chem. Soc., 118, 2359 (1996); Liang, T. et al.: Endocrinol., 117, 571 (1985); Ellsworth, K.P. et al.: J. Steroid Bioche. Mol. Biol., 66, 271 (1998);<br></p>Fórmula:C23H38N2O2Cor e Forma:Off-WhitePeso molecular:374.564-Hydroxy-17β-estradiol-16,16,17-d5
CAS:Produto Controlado<p>Applications A labelled metabolite of Estradiol.<br>References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985), Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991), Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998), Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000),<br></p>Fórmula:C182H5H19O3Cor e Forma:NeatPeso molecular:293.41Lithocolic acid
CAS:Pureza:98.0%Cor e Forma:Solid, White to very pale yellow powderPeso molecular:376.58099365234375Dexamethasone-biotin
CAS:Produto Controlado<p>Applications Dexamethasone-biotin is biotin labelled Dexamethasone. Dexamethasone is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Fórmula:C36H53FN4O6SCor e Forma:NeatPeso molecular:688.8917-epi-Ethynyl Estradiol
CAS:Produto Controlado<p>Impurity Ethinylestradiol EP Impurity A<br>Applications 17-epi-Ethynyl Estradiol (Ethinylestradiol EP Impurity A) is the epimer derivative of Ethynyl Estradiol (E685100). An impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pomper, M., et al: J. Med. Chem., 33, 3143 (1990), Vulliet, E., et al.: Anal. Bioanal. Chem., 387, 2143 (2007), Muller, M., et al.: Environ. Toxicol. Chem., 27, 1649 (2008),<br></p>Fórmula:C20H24O2Cor e Forma:White To Off-WhitePeso molecular:296.406α-Methyl Hydrocortisone
CAS:<p>Applications A metabolite of Cortisone (C696500).<br>References Mashkovskii, M., et al.: Med. Agents, 2, 34 (2002),<br></p>Fórmula:C22H32O5Cor e Forma:Off-White To BeigePeso molecular:376.49Hexestrol
CAS:Produto Controlado<p>Applications Estrogen; antineoplastic (hormonal).<br>References Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 11, 347 (1982),<br></p>Fórmula:C18H22O2Cor e Forma:Off-WhitePeso molecular:270.37Danazol
CAS:Produto Controlado<p>Applications Danazol is an anterior pituitary supressant. Danazol is an anabolic steroid derivative of ethisterone, with mild androgenic side effects (an impeded androgen). Antigonadotropin.<br>References Ahn, Y.S., et al.: N. Engl. J. Med., 308, 1396 (1983),<br></p>Fórmula:C22H27NO2Cor e Forma:White To Light YellowPeso molecular:337.46Isoflupredone
CAS:Produto Controlado<p>Applications Anti-inflammatory.<br>References Buchwald, P., et al.: Steroids, 73, 193 (2008), Holbeck, S., et al.: Mol. Endocrinol., 24, 1287 (2010),<br></p>Fórmula:C21H27FO5Cor e Forma:NeatPeso molecular:378.4314,15-Dehydro Budesonide
CAS:Produto Controlado<p>Impurity Budesonide EP Impurity E<br>Applications 14,15-Dehydro Budesonide (Budesonide EP Impurity E) is a Budesonide (B689490) impurity.<br>References Aherne, G., et al.: J. Steroid Biochem., 17, 559 (1982), Assi, K., et al.: J. Pharm. Biomed. Anal., 41, 325 (2006),<br></p>Fórmula:C25H32O6Cor e Forma:WhitePeso molecular:428.518Pregnenolone Carbonitrile
CAS:Produto Controlado<p>Applications Pregnenolone Carbonitrile is a glucocorticoid receptor antagonist that induces the expression of the CYP3A family of steroid hydroxylases and modulates sterol and bile acid biosynthesis in vivo. Pregnenolone Carbonitrile is an an activator of rat pregnane X receptor (PXR).<br>References Kliewer, S.A., et. al.: Cell, 92, 73 (1998); Savas, U., et. al.: Drug Metab. Dispos., 28, 529 (2000)<br></p>Fórmula:C22H31NO2Cor e Forma:NeatPeso molecular:341.49Latanoprost Acid-d4(>85%)
CAS:Produto Controlado<p>Applications Latanoprost Acid-d4 is the labeled analogue of Latanoprost Acid (L177310), a metabolite of Latanoprost. Latanoprost Acid (L177310) is a potent, selective FP prostanoid receptor agonist, a F-series Prostaglandin analog and is 200 times as potent as isopropyl ester form.<br>References Sjoquist, B., et al.: Drug Metab. Dispos., 26, 745 (1998), Watson, P., et al.: Drugs Today, 35, 449 (1999), Kashiwagi, K., et al.: Exp. Eye Res., 74, 41 (2002),<br></p>Fórmula:C23H30D4O5Pureza:>85%Cor e Forma:ColourlessPeso molecular:394.5417β-Estradiol 17β-D-Glucuronide
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A metabolite of Estradiol (E888000).<br>References Agasan, A., et al.: J. Immunol. Methods., 177, 251 (1994), Stone, R., et al.: Science, 265, 308 (1994), Tacey, R., et al.: J. Pharm. Biomed. Anal., 2, 1303 (1994),<br></p>Fórmula:C24H32O8Cor e Forma:Off White SolidPeso molecular:448.5121-Chloro-9-fluoro-11b,17-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione 17-Propionate (>90%)
CAS:<p>Impurity Clobetasol Propionate EP Impurity C<br>Applications 21-Chloro-9-fluoro-11β,17-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 17-Propionate (Clobetasol Propionate EP Impurity C) is an impurity of Clobetasol 17-Propionate (C583500), an topical corticosteroid with anti-inflammatory properties.<br>References Sugai, S., et al.: Chem. Pharma. Bull., 31, 12 (1983);<br></p>Fórmula:C25H32ClFO5Cor e Forma:NeatPeso molecular:466.974-Hydroxy Atorvastatin-d5 Disodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A deuterated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),<br></p>Fórmula:C33H28D5FN2Na2O6Cor e Forma:NeatPeso molecular:623.63Limaprost
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsuboi, T., et al.: Arch. Int. Pharmacodyn., 247, 89 (1980), Adaikan, P.G., et al.: Prostaglandins Med., 6, 449 (1981), Kottegoda, S.R., et al.: Prostaglandins Leukotrienes Med., 8, 343 (1982), Ishizaki, T., et al.: Chest, 85, 382 (1984),<br></p>Fórmula:C22H36O5Cor e Forma:NeatPeso molecular:380.5216a-Hydroxy Progesterone
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 16α-Hydroxyprrogesterone is a hydroxylated metabolite of Progesterone (P755900). 16α-Hydroxyprogesterone binds to human progesterone receptors hPR-A and hPR-B and act as an agonist for both receptors.<br>References Ikonen, M. et al.: Nature, 212, 716 (1966); Storbeck, K.-H. et al.: Mol. Cell. Endocrinol., 336, 92 (2011);<br></p>Fórmula:C21H30O3Cor e Forma:Off-WhitePeso molecular:330.463-O-Methyl Estrone
CAS:Produto ControladoFórmula:C19H24O2Cor e Forma:White To Dark BrownPeso molecular:284.39Betamethasone 11,21-Diacetate
CAS:Produto Controlado<p>Impurity Betamethasone Acetate EP Impurity C<br>Applications Betamethasone 11β,21-Diacetate is an impurity of Betamethasone 21-Acetate (B327025); a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.<br>References Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001); Seidler, J., et al.: J. Med. Chem., 46, 4477 (2003); Alsenz, J., et al.: J. Pharm. Sci., 96, 1748 (2007)<br></p>Fórmula:C26H33FO7Cor e Forma:WhitePeso molecular:476.53Cholesterol-d7
CAS:Produto Controlado<p>Applications Labelled Cholesterol (C432501). Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones.<br>References Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),<br></p>Fórmula:C272H7H39OCor e Forma:NeatPeso molecular:393.70∆6-Testosterone
CAS:Produto Controlado<p>Impurity Testosterone Decanoate EP Impurity I<br>Applications A metabolite of Testosterone (T155000). Controlled substance.<br>References Peng, S., et al.: Steroids, 67, 39 (2002), Pozo, O., et al.: Drug Metab. Dispos., 37, 2153 (2009),<br></p>Fórmula:C19H26O2Cor e Forma:Beige To Light BrownPeso molecular:286.40Testosterone β-D-Glucuronide Monosodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Metabolite of Testosterone (T155000).<br>References Shibata, N., et al.: Biochem. J., 368, 783 (2002), Sonneveld, E., et al.: Toxicol. Sci., 83, 136 (2005), Schulze, J., et al.: J. Clin. Endocrinol. Metab., 93, 2500 (2008), Sten, T., et al.: Drug Metab. Disposition, 37, 417 (2009),<br></p>Fórmula:C25H35O8·NaCor e Forma:White To Off-WhitePeso molecular:486.53Testosterone Enanthate
CAS:Produto Controlado<p>Applications Testosterone Enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.<br>References Janjic, M.M., et al.: Reproduct. Toxicol., 34, 686 (2012); Lacreuse, A., et al.: Physiol. Behaviour., 106, 229 (2012);<br></p>Fórmula:C26H40O3Cor e Forma:Colourless To Off-WhitePeso molecular:400.59Dihydro Dutasteride
CAS:<p>Applications Dihydro Dutasteride is an impurity arose during the process development of Dutasteride (D735000).<br>References Solomons, W., et al.: J. Pharma. Sci., 63, 19 (1974), Rasmusson, G., et al.: J. Med. Chem., 29, 2298 (1986),<br></p>Fórmula:C27H32F6N2O2Cor e Forma:NeatPeso molecular:530.551,2-Dihydro Dexamethasone
CAS:<p>Applications A derivatives of Dexamethasone (D298800), an analog of cortical hormones.<br>References Giesen, E.M., et al.: Molec. Cell. Endocrinol., 22, 153 (1981),<br></p>Fórmula:C22H31FO5Cor e Forma:White To Light BeigePeso molecular:394.484’-Hydroxy Dutasteride
Produto Controlado<p>Applications 4’-Hydroxy Dutasteride is an impurity of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Fórmula:C27H30F6N2O3Cor e Forma:NeatPeso molecular:544.53(6a,11b)-17,21-Bis(acetyloxy)-6,9-difluoro-11-hydroxy-pregna-1,4-diene-3,20-dione
CAS:Produto ControladoFórmula:C25H30F2O7Cor e Forma:NeatPeso molecular:480.5Estradiol Enanthate
CAS:<p>Applications Estradiol Enanthate has been used as an injectable contraceptive.<br>References Coutinho, E.M., et. al.: Contraception, 73, 249 (2006)<br></p>Fórmula:C25H36O3Cor e Forma:BeigePeso molecular:384.556-Bromo-betamethasone 17,21-Dipropionate
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 6-Bromo-Betamethasone 17,21-Dipropionate (Betamethasone Dipropionate EP Impurity H) is an impurity of Betamethasone (B327000), a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977); Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002); Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005)<br></p>Fórmula:C28H36BrFO7Cor e Forma:NeatPeso molecular:583.485-ANDROSTEN-3,17-DIONE
CAS:Produto Controlado<p>Applications 5-Androsten-3,17-dione has been used in the synthetic preparation of androstenediones for treatment of hormone-related disorders.<br>References Davies, H., et al.: U.S. (2011), WO 2011127232 A2<br></p>Fórmula:C19H26O2Pureza:>90%Cor e Forma:NeatPeso molecular:286.4117β-Estradiol 3-β-D-Glucuronide
CAS:Produto Controlado<p>Applications A metabolite of Estradiol (E888000).<br>References Agasan, A., et al.: J. Immunol. Methods., 177, 251 (1994), Stone, R., et al.: Science, 265, 308 (1994), Tacey, R., et al.: J. Pharm. Biomed. Anal., 2, 1303 (1994),<br></p>Fórmula:C24H32O8Cor e Forma:White To Off-WhitePeso molecular:448.51Paricalcitol
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Synthetic analog of vitamin D. Antihyperparathyroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sidek, H., et al.: Biochim. Biophys. Acta, 801, 26 (1984), Ciftci, M., et al.: J. Pharmacol., 54, 275 (2002),<br></p>Fórmula:C27H44O3Cor e Forma:NeatPeso molecular:416.6421-O-Acetyl Dexamethasone-d5
CAS:Produto Controlado<p>Applications Isotope labelled intermediate in the synthesis of Dexamethasone (D298800), a glucocorticoid anti-inflammatory agent.<br>References Liu, Y., et al.: Anal. Bioanal. Chem., 395, 591 (2009), Rodgers, A., et al.: Chem. Res. Toxicol., 23, 724 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),<br></p>Fórmula:C24D5H26FO6Cor e Forma:NeatPeso molecular:439.536β-Hydroxy Budesonide
CAS:Produto ControladoFórmula:C25H34O7Cor e Forma:White To Light YellowPeso molecular:446.53Quinestrol
CAS:Produto Controlado<p>Applications Quinestrol is an estrogen-like compound.<br></p>Fórmula:C25H32O2Cor e Forma:NeatPeso molecular:364.52Travoprost
CAS:<p>Stability Light Sensitive<br>Applications Travoprost is a selective FP prostaglandin receptor agonist used to treat glaucoma (1,2).<br>References (1) Hellberg, M.R., et al.: J. Ocul. Pharmacol. Ther., 17, 421 (2001) (2) Schuman, J.S., et al.: Am. J. Ophthalmol., 140, 242 (2005)<br></p>Fórmula:C26H35F3O6Cor e Forma:Colourless To BeigePeso molecular:500.55Pregnenolone-d4
CAS:Produto Controlado<p>Applications Pregnenolone-d4, is the labeled analogue of the Pregnenolone (P712200), which is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens.<br>References Bjondahl, K., et al.: Med. Biol., 54, 454 (1976), Geick, A., et al.: J. Biol. Chem., 276, 14581 (2001), Johnson, D., et al.: Toxicol. Sci., 66, 16 (2002), Abe, C., et al.: Lipids, 42, 637 (2007),<br></p>Fórmula:C212H4H28O2Cor e Forma:Off-WhitePeso molecular:320.50Pregnenolone-d6
CAS:Produto Controlado<p>Applications Pregnenolone-d6 is the labeled analogue of Pregnenolone (P712200), a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA antagonist and increases neurogenesis in the hippocampus. It is a modulator of cytochrome P 450-3A.<br>References Bjondahl, K., et al.: Med. Biol., 54, 454 (1976); Geick, A., et al.: J. Biol. Chem., 276, 14581 (2001); Johnson, D., et al.: Toxicol. Sci., 66, 16 (2002); Abe, C., et al.: Lipids, 42, 637 (2007)<br></p>Fórmula:C21D6H26O2Cor e Forma:NeatPeso molecular:322.516-Defluoro-6-oxo-fluticasone Propionate
<p>Stability Temperature Sensitive<br>Applications 6-Defluro-6-oxo-fluticasone Propionate is a derivative of Flumethasone (F455000), a glucocorticoid, anti-inflammatory.<br>References Matuszewski, B, et al.: Anal. Chem., 75, 3019 (2003), Fekete, S., et al.: J. Pharm. Biomed. Anal., 49, 64 (2009),<br></p>Fórmula:C25H30F2O6SCor e Forma:Off-WhitePeso molecular:496.56(11b,16a)-9-Fluoro-11,21,21-trihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
CAS:Produto ControladoFórmula:C24H31FO7Cor e Forma:Light YellowPeso molecular:450.506-Keto Ethynyl Estradiol
CAS:Produto Controlado<p>Impurity Ethinylestradiol EP Impurity G<br>Applications An oxidative tranformation product of Norethindrone Acetate (N675990) and Ethynyl Estradiol (E685100).<br>References Ekhato, I.V. et al.: Steroids, 67, 165 (2002); Lane. P.A. et al.: J. Pharmac. Sci., 76, 44 (1987);<br></p>Fórmula:C20H22O3Cor e Forma:Light Yellow To Light BrownPeso molecular:310.39Dexamethasone Hemisuccinate
CAS:<p>Applications Dexamethasone Hemisuccinate is a derivative of Dexamethasone (D298800); a glucocorticoid used as an anti-inflammatory agent. It regulates T cell survival, growth, and differentiation. Dexamethasone also inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995); Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999); Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Fórmula:C26H33FO8Cor e Forma:NeatPeso molecular:492.53Cortisol-9,12,12-d3
CAS:Produto Controlado<p>Applications Isotope labelled Cortisol (H714615) a topical corticosteroid, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland . Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.<br>References Vigore, L., et al.: Cancer Biol Ther.. 15. :699 (2014); Puurunen, J. et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009);<br></p>Fórmula:C21D3H27O5Cor e Forma:NeatPeso molecular:365.48Lanatoside C
CAS:<p>Stability Hygroscopic<br>Applications Glycosides isolated from various species of Digitalis. Cardiotonic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Novotny, J., et al.: J. Biol. Chem., 258, 14433 (1983), Farr, C., et al.: J. Med. Chem., 45, 3257 (2002), Van Dongen, M., et al.: Drug Discov. Today, 7, 471 (2002),<br></p>Fórmula:C49H76O20Cor e Forma:White To Off-WhitePeso molecular:985.12Testosterone-2,2,4,6,6-d5 (1 mg/ml in Acetonitrile)
CAS:Produto ControladoFórmula:C192H5H23O2Cor e Forma:ColourlessPeso molecular:293.46Altrenogest
CAS:Produto Controlado<p>Applications A synthetic progestational agent used in veterinary medicine for the control of estrus in mares.<br>References Machnik M. et al.: J. Vet. Phamacol. Therap., 30, 86 (2007); Goncalves dos Santos, J.M. et al.: Anim. Reprod. Sci., 84, 407 (2004);<br></p>Fórmula:C21H26O2Cor e Forma:Light YellowPeso molecular:310.4320,21-Dehydro Spironolactone
CAS:Produto ControladoFórmula:C24H30O4SCor e Forma:NeatPeso molecular:414.56(17α)-13-Ethyl-3-methoxy-18,19-dinorpregna-3,5-dien-20-yn-17-ol
CAS:Produto Controlado<p>Applications Norgestrel (N689500) impurity.<br>References Gorog, S., et al.: J. Chromatogr., 400 177 (1987),<br></p>Fórmula:C22H30O2Cor e Forma:NeatPeso molecular:326.47S-deacetyl spironolactone
CAS:<p>Applications A metabolite of Spironolactone.<br>References Morris, R., et al.: Eur. J. Clin. Pharmacol., 34, 233 (1988), Dasgupta, A., et al.: Am. J. Clin. Pathol., 111, 406 (1999)<br></p>Fórmula:C22H30O3SCor e Forma:NeatPeso molecular:374.54a-Acetyl Digoxin
CAS:Produto Controlado<p>Applications Digoxin derivative, a cardiotonic glycosides steroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yoshida, F., et al.: J. Med. Chem., 43, 2575 ( 2000), Turner, J., et al.: Pharm. Res., 21, 68 (2004), Wang, J., et al.: Anal. Chim. Acta, 601, 156 (2007),<br></p>Fórmula:C43H66O15Cor e Forma:NeatPeso molecular:822.987,7’-Nonane-1,9-diylbis[estra-1,3,5(10)-triene-3,17β-diol](Mixture of Diastereomers)
Produto Controlado<p>Applications Fulvestrant (F862500) impurity D.<br></p>Fórmula:C45H64O4Cor e Forma:NeatPeso molecular:668.99E,E-Dienestrol
CAS:Produto Controlado<p>Applications A metabolite of Diethylstilbestrol.<br>References Liehr, J.G., et al.: Steroids, 40, 713 (1982),<br></p>Fórmula:C18H18O2Cor e Forma:NeatPeso molecular:266.336-Oxo Norethindrone Acetate
CAS:<p>Impurity Norethindrone Acetate EP Impurity G<br>Applications 6-Oxo Norethindrone Acetate (Norethindrone Acetate EP Impurity G) is an oxidative product of Norethindrone acetate (N675990).<br>References Schroff, A.P., et al.: Anal. Profiles Drug Subs., 4, 268 (1975); Singh, H., et al.: Am. J. Obstet. Gynecol., 135, 409 (1979)<br></p>Fórmula:C22H26O4Cor e Forma:NeatPeso molecular:354.44Testosterone-d3 Propionate
CAS:Produto Controlado<p>Applications Isotope labelled Testosterone Propionate (T155045), Anabolic steroid. Androgen.Controlled substance.<br>References Glass, A., et al.: J. Clin. Endocrinol. Metab., 45, 1211 (1977), Behre, H., et al.: Eur. J. Endocrinol., 140, 414 (1999), Nieschlag, E., et al.: Steroids, 68, 965 (2003), Wang, C., et al.: J. Clin. Endocrinol. Metab., 91, 460 (2006),<br></p>Fórmula:C222H3H29O3Cor e Forma:NeatPeso molecular:347.51Corticosterone
CAS:Produto Controlado<p>Applications Glucocorticoid; an intermediate in the biosynthesis of aldosterone, isolated from the adrenal cortex.<br>References Schmidt, M., et al.: Endocrinol., 150, 2709 (2009), Bailey, M., et al.: J. Immunol., 182, 7888 (2009), Brunton, P., et al.: J. Neurosci., 29, 6449 (2009), Pruett, S., et al.: Toxicol. Sci., 109, 265 (2009),<br></p>Fórmula:C21H30O4Cor e Forma:NeatPeso molecular:346.46Estradiol Acetate
CAS:<p>Applications Estradiol acetate is used a reactant in the preparation of a modifier conjugate through a physiologically cleavable bond for enhanced drug transport across membranes.<br>References Hale, R., et al.: PCT Int. Appl. (1993), WO 9325197 A1 19931223.<br></p>Fórmula:C20H26O3Cor e Forma:NeatPeso molecular:314.42Dexamethasone Valerate
CAS:<p>Impurity Betamethasone Valerate EP Impurity C<br>Stability Hygroscopic<br>Applications Dexamethasone Valerate (Betamethasone Valerate EP Impurity C) is an impurity of Dexamethasone (D298800), which is a glucocorticoid that is used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Fórmula:C27H37FO6Cor e Forma:Off-WhitePeso molecular:476.5811α-Hydroxy Progesterone
CAS:Produto Controlado<p>Applications Progesterone (P755900) metabolite.<br>References Christy H., et al.: J. Steroid Biochem., Mol., Biol., 116, 171 (2009), Peristera, O., et al.: Toxicol., Lett., 189, 219 (2009), Mori, T., et al.: Toxicol., Lett., 186, 123 (2009),<br></p>Fórmula:C21H30O3Cor e Forma:Off-WhitePeso molecular:330.4617β-Estradiol-d3 17-Acetate 3-β-D-Glucuronide
Produto Controlado<p>Applications A labelled Estradiol (E888000) derivative.<br></p>Fórmula:C26H31D3O9Cor e Forma:NeatPeso molecular:493.563b,5a,6b-Trihydroxycholestane
CAS:<p>Applications Cholesterol analog. Useful for treatment of hyperlipemia, arteriosclerosis, diabetes, obesity.<br>References Watson, K., et al.: J. Clin. Invest., 93, 2106 (1994), Wada, T., et al.: Circ. Res., 84, 166 (1999), Engelse, M., et al.: Cardiovasc. Res., 52, 281 (2001), Landis, M., et al.: J. Biol. Chem., 277, 4713 (2002),<br></p>Fórmula:C27H48O3Cor e Forma:NeatPeso molecular:420.67Dexamethasone-d5 Acid Ethyl Ester
Produto Controlado<p>Applications Isotope Labelled Dexamethasone Acid Ethyl Ester is a derivative of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Fórmula:C23D5H26FO5Cor e Forma:NeatPeso molecular:411.52(20S)-Dexamethasone Epimeric Glycolic Acid
CAS:Fórmula:C22H29FO6Cor e Forma:NeatPeso molecular:408.464-Methoxy-d3 17β-estradiol (>90%)
CAS:Produto Controlado<p>Applications A labelled metabolite of 17β-Estradiol.<br>References Cushman, M., et al.: J. Med. Chem., 38, 2041 (1995), D’Amato, R.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 3964 (1994), Forsis, T., et al.: Nature, 368, 237 (1994)<br></p>Fórmula:C19H23D3O3Pureza:>90%Cor e Forma:NeatPeso molecular:305.4321-Desacetyl Deflazacort
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A metabolite of Deflazacort, a systemic corticosteroid, a derivative of prednisolone and used for rheumatoid arthritis and lupus.<br>References Hahn, T.J., et al.: Calcif. Tissue Int., 31, 109 (1980), Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1984)<br></p>Fórmula:C23H29NO5Cor e Forma:White To Off-WhitePeso molecular:399.4811-Deoxy Corticosterone-d7
CAS:Produto Controlado<p>Applications Labelled Deoxycorticosterone. A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700).<br>References Bohl, C., et al.: J. Med.Chem., 47, 3765 (2004), Smith, J., et al.: Steroids, 73, 1160 (2008),<br></p>Fórmula:C21H23D7O3Cor e Forma:White To Off-WhitePeso molecular:337.5(3β)-Cholesta-4,6-dien-3-ol
CAS:<p>Applications (3β)-Cholesta-4,6-dien-3-ol is a Cholesterol (C432501) and Cholestane (C431700) derivative which has the potential to act as an antiinflammatory and antifungal compound.<br>References Felicio, R. et al.: J. Pharm. Biomed. Anal., 52, 763 (2010); Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),<br></p>Fórmula:C27H44OCor e Forma:NeatPeso molecular:384.6421-Dehydro Budesonide
CAS:Produto Controlado<p>Impurity Budesonide EP Impurity D<br>Stability Hygroscopic<br>Applications 21-Dehydro Budesonide (Budesonide EP Impurity D) is a Budesonide (B689490) impurity.<br>References Backes, S., et al.: Drug Metab. Rev., 34, 157 (2002), Vermeer, H., et al.: Clin. Endocrinol., 59, 49 (2003), Assi, K., et al.: J. Pharm. Biomed. Anal., 41, 325 (2006),<br></p>Fórmula:C25H32O6Cor e Forma:NeatPeso molecular:428.52Digoxin
CAS:Produto Controlado<p>Applications Cardiotonic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aronson, J.K., et al.: Clin. Pharmacokinet, 5,137 (1980), Foss, P.R.B., Anal. Profiles Drug Subs., 9, 207 (1980),<br></p>Fórmula:C41H64O14Cor e Forma:WhitePeso molecular:780.94Betamethasone Tripropionate
CAS:<p>Impurity Betamethasone Dipropionate EP Impurity G<br>Applications Betamethasone Tripropionate (Betamethasone Dipropionate EP Impurity G) is a Betamethasone (B327000) related compound.<br>References Grootveld, M., et al.: Biochem. Pharmacol., 37, 271 (1988), Chen, B., et al.: Steriods, 74, 30 (2009), Mikami, E., et al.: J. Pharm. Biomed. Anal., 28, 261 (2002),<br></p>Fórmula:C31H41FO8Cor e Forma:NeatPeso molecular:560.65Digoxin-d3
CAS:Produto Controlado<p>Applications Labelled Diogoxin (D446575). Cardiotonic. A representative lot is 95.4% d3, 3.4% d2, 1.2% d1 no dectable d0.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aronson, J.K., et al.: Clin. Pharmacokinet, 5,137 (1980), Foss, P.R.B., Anal. Profiles Drug Subs., 9, 207 (1980),<br></p>Fórmula:C412H3H61O14Cor e Forma:Off White PowderPeso molecular:783.962-Hydroxy Atorvastatin Dihydrate Monosodium Salt
CAS:<p>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),<br></p>Fórmula:C33H38FN2NaO8Cor e Forma:NeatPeso molecular:632.65Fulvestrant-d3
CAS:Produto ControladoFórmula:C32H44D3F5O3SCor e Forma:White To Off-WhitePeso molecular:609.79δ7,9(11)-Dexamethasone
CAS:<p>Stability Hygroscopic<br>Applications Dexamethasone (D298800) process impurity.<br></p>Fórmula:C22H26O4Cor e Forma:NeatPeso molecular:354.446α-Hydroxy Androstenedione
CAS:Produto Controlado<p>Applications A metabolite of Androstenedione (A637550).<br>References Gazdar, A., et al.: Cancer Res., 50, 5488 (1990), Levesque, J., et al.: Steroids, 70, 305 (2005), Lootens, L., et al.: Drug Metab. Dispos., 37, 2367 (2009),<br></p>Fórmula:C19H26O3Cor e Forma:NeatPeso molecular:302.41Dexamethasone Phenylpropionate
CAS:Produto ControladoFórmula:C31H37FO6Cor e Forma:NeatPeso molecular:524.623-Keto Fluvastatin Sodium Salt
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications An impurity of Fluvastatin.<br></p>Fórmula:C24H23FNO4·NaCor e Forma:NeatPeso molecular:431.43Ciclesonide
CAS:Produto Controlado<p>Applications A glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.<br>References Fukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001),<br></p>Fórmula:C32H44O7Cor e Forma:White To Off-WhitePeso molecular:540.6911-Deoxy Prednisolone
CAS:Produto Controlado<p>Impurity Prednisolone EP Impurity J<br>Applications 11-Deoxy Prednisolone (Prednisolone EP Impurity J) is a Prednisolone (P703740) derivative as a corticosteroid.<br>References Kobayashi, Y., et al.: Biol. Pharm. Bull., 16, 1175 (1993), Ogata, M., et al.: J. Pharm. Sci., 87, 91 (1998), Hou, S., et al.: J. Pharm. Biomed. Anal., 24, 371 (2001),<br></p>Fórmula:C21H28O4Cor e Forma:Light BrownPeso molecular:344.44
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