Esteroides e Derivados
Os esteroides são compostos orgânicos que possuem uma estrutura de quatro anéis fundidos, conhecida como núcleo esteroide. Esse núcleo pode estar ligado a vários grupos funcionais que modificam suas propriedades e funções biológicas. Os esteroides desempenham um papel fundamental na regulação dos processos metabólicos e hormonais. São utilizados na medicina para tratar distúrbios inflamatórios, doenças autoimunes e desequilíbrios hormonais. Além disso, alguns derivados de esteroides possuem potentes propriedades anti-inflamatórias, como os corticosteroides. Em terapias específicas, são utilizados para reduzir a inflamação e controlar a dor em diversas doenças.
Na CymitQuimica, oferecemos uma variedade de esteroides e seus derivados para pesquisa e desenvolvimento farmacêutico.
Foram encontrados 4967 produtos de "Esteroides e Derivados"
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Difluprednate
CAS:Produto Controlado<p>Applications A corticosteroid (derivative of prednisolone), approved for the treatment of post-operative ocular inflammation.<br>References Kapp, A., et al.: J. Allergy and Clin. Immunol., 110, 277 (2002), Yasueda, S., et al.: J. Pharm. Biomed. Anal., 30, 1735 (2003), Yamaguchi, M., et al.: Int. J. Pharm., 301, 121 (2005),<br></p>Fórmula:C27H34F2O7Cor e Forma:WhitePeso molecular:508.556-Bromo-betamethasone 17,21-Dipropionate
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 6-Bromo-Betamethasone 17,21-Dipropionate (Betamethasone Dipropionate EP Impurity H) is an impurity of Betamethasone (B327000), a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977); Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002); Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005)<br></p>Fórmula:C28H36BrFO7Cor e Forma:NeatPeso molecular:583.48Triamcinolone-13C3 Acetonide
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A labelled glucocorticoid, antiasthmatic (inhalant); antiallergic (nasal).<br>References Florey, K., et al.: Anal. Profiles Drug Subs., 1, 397 (1972), Bernstein, I.L., et al.: Chest, 81, 20 (1982),<br></p>Fórmula:C2113C3H31FO6Cor e Forma:White To Off-WhitePeso molecular:437.4822-Hydroxy Estrone-d4
CAS:Produto Controlado<p>Applications A labelled metabolite of Estradiol (E888000).<br>References Fishman, H.G, et al.: Biochemistry, 8, 4304 (1969), Ryan, Sugar, J., et al.: J. Clin. Endocrinol. Metab., 50, 137 (1980), Numazawa, M., et al.: Steroids, 38, 149 (1981), Travis, R., et al.: Breast Cancer Res., 5, 239 (2003),<br></p>Fórmula:C182H4H18O3Cor e Forma:GreyPeso molecular:290.3920b-Dihydroprogesterone
CAS:Produto Controlado<p>Impurity Progesterone EP Impurity C<br>Applications 20β-Dihydroprogesterone (Progesterone EP Impurity C) is an impurity of Progesterone (P755900), a steroid hormone secreted by the corpus luteum. Progesterone have various significant physiological roles, such as inducing the maturation and secretory activities of the uterine endothelium and the suppression of ovulation. Progesterone is also implicated in the etiology of breast cancer.<br>References Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),<br></p>Fórmula:C21H32O2Cor e Forma:White To Off-WhitePeso molecular:316.48Testosterone 17β-Hemisuccinate
CAS:Produto ControladoFórmula:C23H32O5Cor e Forma:NeatPeso molecular:388.4979,11-Dehydro Ethynyl Estradiol
CAS:<p>Impurity Ethinylestradiol EP Impurity B<br>Applications 9,11-Dehydro Ethynyl Estradiol (Ethinylestradiol EP Impurity B) is a degradation product of Ethynyl Estradiol (EE); an impurity of Ethynyl Estradiol (E685100).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pang, C., et al.: Steroids, 23, 203 (1974), Leese, M., et al.: J. Med. Chem., 49, 7683 (2006), Krstic, N., et al.: Steroids, 72, 406 (2007),<br></p>Fórmula:C20H22O2Cor e Forma:NeatPeso molecular:294.39Methoxygonadiene (>90%)
CAS:Produto Controlado<p>Applications Max LMG is a progestin derived steroid and not a 17-alpha alkylated steroid. Max LMG is structurally related to RU-486 and acts as an antiprogesterone, decreasing estrogen-like effects.<br>References Eenoo, P.V., et al.: J. Steroid. Biochem. Molec. Biol., 101, 161 (2006); Kafrouni, M. I., Clinical. Gastroenterol. Hepatol., 5, 805 (2007); Ponsoid, K., et al.: Pharmazie., 33, 729 (1978);<br></p>Fórmula:C20H28O2Pureza:>90%Cor e Forma:NeatPeso molecular:300.4411-Dehydrocorticosterone
CAS:Produto Controlado<p>Applications 11-Dehydrocorticosterone is a precursor to corticosterone (C695700), converted by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) which plays a role in glucocorticoid-induced insulin resistance.<br>References Morgan, S. et al.: Diabetes, 58, 2506 (2009);<br></p>Fórmula:C21H28O4Cor e Forma:White To Light YellowPeso molecular:344.44Desonide-13C3
CAS:Produto Controlado<p>Applications Anti-inflammatory.<br>References Phillips, et al.: Toxicol. Appl. Pharmacol., 20, 522 (1971), Sanen, F.J., et al.: Int. J. Clin. Pharmacol. Biopharm., 12, 174 (1975), Tarayre, J.P., et al.: Pharmacol., 19, 323 (1979).<br></p>Fórmula:C2113C3H32O6Cor e Forma:NeatPeso molecular:419.49Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate
CAS:Produto Controlado<p>Impurity Dutateride EP Impurity C<br>Applications Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate (Dutateride EP Impurity C) is a compound synthesized in the production of azasteroids. Used in the inhibition of 5α-reductase and of androgen receptor binding, both major effecters in the male hormonal system.<br>References Ramusson, G. et al.: J. Med. Chem., 29, 2298 (1986);<br></p>Fórmula:C21H31NO3Cor e Forma:White To Off-WhitePeso molecular:345.48(aR,1S,3S,4R)-a,4-Dimethyl-2-oxo-3-(3-oxobutyl)-cyclohexaneacetic Acid
CAS:Produto Controlado<p>Stability Hygroscopic, Unstable in Solution<br>Applications (αR,1S,3S,4R)-α,4-Dimethyl-2-oxo-3-(3-oxobutyl)-cyclohexaneacetic Acid is an impurity of Artemisin (A777500), an active antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Klayman, D.L., et al.: Science, 228, 1049 (1985), Price, R.N., et al.: Expert Opin. Invest. Drugs, 9, 1815 (2000), Meshnick, S.R., et al.: Int. J., Parasitol., 32, 1655 (2002),<br></p>Fórmula:C14H22O4Cor e Forma:NeatPeso molecular:254.32Estrone-d2
CAS:Produto Controlado<p>Applications Isotope labelled Estrone (E889050), which is a metabolite of 17β-Estradiol (E888000). During the metabolism, it is in rapid equilibrium with Estriol (E888960) and 17β-Estradiol (E888000) (1). Causes the feminization of male fish at human and animal waste sites (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Both, D. et al.: Anal. Prof. Drug Subst. 1983 12 pp135-1892. Goodman-Gruen, D. et al.: J. Clin. Endocrinol. Metab. 1996 Aug;81(8):2999-3003.<br></p>Fórmula:C182H2H20O2Cor e Forma:Off-WhitePeso molecular:272.38Spiro[androsta-1,4-diene-6,2'-oxirane]-3,17-dione(Mixture of Diastereomers)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A metabolite of Exemestane (E957000).<br>References Cavalcanti, G. et al.: Steroids 76, 1010 (2011)<br></p>Fórmula:C20H24O3Cor e Forma:NeatPeso molecular:312.4017-epi-Ethynyl Estradiol
CAS:Produto Controlado<p>Impurity Ethinylestradiol EP Impurity A<br>Applications 17-epi-Ethynyl Estradiol (Ethinylestradiol EP Impurity A) is the epimer derivative of Ethynyl Estradiol (E685100). An impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pomper, M., et al: J. Med. Chem., 33, 3143 (1990), Vulliet, E., et al.: Anal. Bioanal. Chem., 387, 2143 (2007), Muller, M., et al.: Environ. Toxicol. Chem., 27, 1649 (2008),<br></p>Fórmula:C20H24O2Cor e Forma:White To Off-WhitePeso molecular:296.40Dexamethasone-biotin
CAS:Produto Controlado<p>Applications Dexamethasone-biotin is biotin labelled Dexamethasone. Dexamethasone is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Fórmula:C36H53FN4O6SCor e Forma:NeatPeso molecular:688.895-β-Pregnane-3-α,20-α-diol
CAS:<p>Applications 5β-Pregnane-3α,20α-diol is a metabolite of Progesterone (P755900).<br>References Beall, et al.: Biochem. J., 31, 35 (1937), Okuda, A., et al.: J. Biol. Chem., 259, 7519 (1984), Russell, D., et al.: Biochemistry, 31, 4737 (1992), Kondo, K., et al.: Eur. J. Biochem., 219, 357 (1994), Westerbacka, J., et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003),<br></p>Fórmula:C21H36O2Cor e Forma:White To Off-WhitePeso molecular:320.51Di-Norbudesonide(Mixture of Diastereomers)
CAS:Produto Controlado<p>Impurity Budesonide EP Impurity B<br>Applications Di-Norbudesonide (Budesonide EP Impurity B) is an impurity of Budesonide (B689490), an antiinflammatory agent.<br></p>Fórmula:C23H30O6Cor e Forma:NeatPeso molecular:402.48Cortisol-9,11,12,12-d4
CAS:Produto Controlado<p>Applications Labelled Cortisol (H714615). Cortisol, or Hydrocortisone, is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.<br>References Hechter, O., et al.: Arch. Biochem. Biophys., 25, 457 (1950), Colingsworth, D.R., et al.: J. Biol. Chem., 203, 807 (1953), Florey, K., et al.: Anal. Profiles Drug Subs., 12, 277 (1983),<br></p>Fórmula:C212H4H26O5Cor e Forma:Off-WhitePeso molecular:366.48
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