Esteroides e Derivados
Os esteroides são compostos orgânicos que possuem uma estrutura de quatro anéis fundidos, conhecida como núcleo esteroide. Esse núcleo pode estar ligado a vários grupos funcionais que modificam suas propriedades e funções biológicas. Os esteroides desempenham um papel fundamental na regulação dos processos metabólicos e hormonais. São utilizados na medicina para tratar distúrbios inflamatórios, doenças autoimunes e desequilíbrios hormonais. Além disso, alguns derivados de esteroides possuem potentes propriedades anti-inflamatórias, como os corticosteroides. Em terapias específicas, são utilizados para reduzir a inflamação e controlar a dor em diversas doenças.
Na CymitQuimica, oferecemos uma variedade de esteroides e seus derivados para pesquisa e desenvolvimento farmacêutico.
Foram encontrados 4964 produtos de "Esteroides e Derivados"
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1,2-Dihydro Triamcinolone
CAS:Produto Controlado<p>Applications 1,2-Dihydro Triamcinolone is a derivative of Triamcinolone (T767165), a glucocorticoid, antiasthmatic (inhalant); antiallergic (nasal).<br>References Florey, K., et al.: Anal. Profiles Drug Subs., 1, 397 (1972); Bernstein, I.L., et al.: Chest, 81, 20 (1982);<br></p>Fórmula:C21H29FO6Cor e Forma:NeatPeso molecular:396.45Prednisolone 21-Sulfate Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Prednisolone 21-Sulfate is a metabolite of Prednisolone (P703740).<br>References Hutzler, J., ET AL.: Drug Metab. Dispos., 30, 355 (2002), Sugiyama, D., et al.: J. Biol. Chem., 278, 43489 (2003), Hagenbuch, B., et al.: Xenobiotica, 38, 778 (2008),<br></p>Fórmula:C21H27NaO8SCor e Forma:NeatPeso molecular:462.49Cortisol-D4 21-Sulfate Potassium Salt
CAS:Produto Controlado<p>Applications Labelled Cortisol-d4 21-Sulfate (C696320). Cortisol 21-Sulfate is a phase II metabolite of Cortisol (H714615).<br>References Spielgelhalder, B., et al.: J. Steroid Biochem., 7, 749 (1976), Vanluchene, E., et al.: J. Chromatogr., 456, 175 (1988), Choi, M., et al.: Steroids, 65, 54 (2000),<br></p>Fórmula:C21H25D4KO8SCor e Forma:NeatPeso molecular:484.6420β-Dihydrocortisone
CAS:Produto Controlado<p>Applications 20β-Dihydrocortisone is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.<br>References Reach, G., et. al.: Steroids, 30, 621 (1977); Vigore, L., et al.: Cancer Ther., 6, 699 (2008); Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009); Lemos, D., et al.: J. Endocrinol., 201, 275 (2009); Chen, S., et al.: Am. J. Physiol., 296 (2009)<br></p>Fórmula:C21H30O5Cor e Forma:NeatPeso molecular:362.46Testosterone-16,16,17-d3 17-Decanoate
CAS:Produto Controlado<p>Applications Testosterone 17-Decanoate-d3, is the labeled analogue of Testosterone 17-Decanoate (T155120), an ester of Testosterone (T155000). Testosterone 17-Decanoate, can be used as a potential long-acting male contraceptive, with the combination of subcutaneous etonogestrel implants.<br>References Brady, B. M., et al.: Human Reproduction, 21 (1), 285 (2006); Themmen, A., et al.: Endocr. Rev. 21, 551 (2000);<br></p>Fórmula:C292H3H43O3Cor e Forma:NeatPeso molecular:445.691-(2,4-Dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one
CAS:Produto Controlado<p>Applications 1-(2,4-Dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one is an antioxidant and also has anti cancer effects on human breast cancer MCF-7 cells and Hep3B human hepatocellular carcinoma cells.<br>References Choi, Eun Jeong, et al.: Mol. Med. Rep., 9(1), 328-332 (2014);Choi, Eun Jeong, et al.: Onco.Lett., 6(6), 1784-1788 (2013);Choi, Eun Jeong, et al.: Inter. J.of Mol. Med., 31(3), 726-730 (2013)<br></p>Fórmula:C15H14O4Cor e Forma:NeatPeso molecular:258.27Dexamethasone 21-Palmitate
CAS:Produto Controlado<p>Applications A corticosteroid prodrug for the treatment of eye disorders.<br>References Benameur, H., et al.: J. Pharm. Pharmacol., 47, 812 (1995), Tauchi, Y., et al.: Biol. Pharm. Bull., 24, 925 (2001), Chono, S., et al.: J. Drug Targeting, 13, 407 (2005),<br></p>Fórmula:C38H59FO6Cor e Forma:NeatPeso molecular:630.87Dexamethasone b-D-Glucuronide Sodium (>90%)
CAS:Produto Controlado<p>Applications Sodium salt of Dexamethasone β-D-Glucuronide is a potential prodrug for colonic delivery of the antiinflammatory corticosteroid Dexamethasone.<br>References Fotsis, T., et al.: J. Steroid Biochem., 14, 457 (1981), Choi, M., et al.: Steroids, 65, 54 (2000); Haeberlin, B. et al.: Pharm Res., 10, 1553 (1993);<br></p>Fórmula:C28H36FNaO11Cor e Forma:NeatPeso molecular:590.57Testosterone-d8
CAS:Produto Controlado<p>Applications Labelled Testosterone (T155000). Principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.Controlled substance (anabolic steroid). Androgen.<br>References McFarland, K., et al.: Science, 245, 494 (1989), Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998), Themmen, A., et al.: Endocr. Rev. 21, 551 (2000), Kumar, R., et al.: Biol. Reprod., 65, 710 (2001),<br></p>Fórmula:C19H20D8O2Cor e Forma:White To Off-WhitePeso molecular:296.47Digitoxigenin Mono-β-D-digitoxoside
CAS:Produto ControladoFórmula:C29H44O7Cor e Forma:White To Off-WhitePeso molecular:504.663-Aminobenzotrifluoride
CAS:Produto Controlado<p>Applications 3-Aminobenzotrifluoride is a known human toxin that can cause bacterial mutation and hepatocyte unscheduled DNA synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reinhold, D., et al.: T. ASAE, 49, 2077 (2006); Thompson, C., et al.: Environ. Mutagen., 5, 803 (1983)<br></p>Fórmula:C7H6F3NCor e Forma:YellowPeso molecular:161.129-Chloro Triamcinolone Acetonide 21-Acetate
CAS:Produto Controlado<p>Applications Triamcinolone Acetonide (T767165) impurity.<br></p>Fórmula:C26H33ClO7Cor e Forma:WhitePeso molecular:492.9893-epi-25-Hydroxy Vitamin D3
CAS:<p>Stability Light Sensitive, Temperature Sensitive<br>Applications The epimer metabolite of Calcifediol or 25-hydroxyvitamin D3 (C125700).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sakaki, T., et al.: Eur. J. Biochem., 267, 6158 (2000), Kamao, M., et al.: J. Biol. Chem., 278, 1463 (2003),<br></p>Fórmula:C27H44O2Cor e Forma:NeatPeso molecular:400.642-Methyl Ethynyl Estradiol
CAS:Produto Controlado<p>Impurity Ethinylestradiol EP Impurity M<br>Applications 2-Methylethynylestradiol (Ethinylestradiol EP Impurity M) is a 17α-ethynyl steroid. 2-Methylethynylestradiol is an impurity of Ethynylestradiol (E685100).<br></p>Fórmula:C21H26O2Cor e Forma:NeatPeso molecular:310.43(3E)-17-Deacetylnorgestimate
CAS:<p>Applications E-17-Deacetylnorgestimate is a metabolite of Norgestimate. A contraceptive for birth control used by women.Note- The oxime isomerizes when: 1) Heated in any solvent or heating the crystalline form 2) Dissolved in MeOH at room temperature very quickly 3) Dissolved in acetone or CHCl3 at room temperature in a couple of hours at room temperature4) In EtOAc or EtOAc/isooctane over a couple of days at RT. It is stable in the crystalline form.<br>References Phillips, A., et al.: Steroids, 55, 373 (1990); Rabiolo, A., et al.: Arch. Gynecol. Obstet., 294, 1317 (2016)<br></p>Fórmula:C21H29NO2Cor e Forma:Off-WhitePeso molecular:327.46Testosterone Undecanoate-d21
CAS:Produto ControladoFórmula:C30H27D21O3Cor e Forma:Off-WhitePeso molecular:477.846-Oxo Boldione
CAS:Produto Controlado<p>Applications A derivative of Exemestane (E957000), a new aromatase inhibitor.<br>References Thompson, E., et al.: J. Biol. Chem., 249, 5364 (1974), Cole, P., et al.: J. Med. Chem., 33, 2933 (1990), Buzzetti, F., et al.: Steroids, 58, 527 (1993),<br></p>Fórmula:C19H22O3Cor e Forma:Off-White To Light YellowPeso molecular:298.38Bexarotene-13C4
CAS:Produto Controlado<p>Applications Labelled Bexarotene (B336750). Used as an antineoplastic. A selective retinoid X receptor (RXR) agonist.<br>References Boehm, M.F., et al.: J. Med. Che., 37,2930 (1994), Gottardis, M.M., et al.: Cancer Res., 56, 5566 (1996), Mukherjee, R., et al.: Nature, 386, 407 (1997), Miller, V.A., et al.: J. Clin. Oncol., 15, 790 (1997)<br></p>Fórmula:C4C20H28O2Cor e Forma:NeatPeso molecular:352.45
