Esteroides e Derivados
Os esteroides são compostos orgânicos que possuem uma estrutura de quatro anéis fundidos, conhecida como núcleo esteroide. Esse núcleo pode estar ligado a vários grupos funcionais que modificam suas propriedades e funções biológicas. Os esteroides desempenham um papel fundamental na regulação dos processos metabólicos e hormonais. São utilizados na medicina para tratar distúrbios inflamatórios, doenças autoimunes e desequilíbrios hormonais. Além disso, alguns derivados de esteroides possuem potentes propriedades anti-inflamatórias, como os corticosteroides. Em terapias específicas, são utilizados para reduzir a inflamação e controlar a dor em diversas doenças.
Na CymitQuimica, oferecemos uma variedade de esteroides e seus derivados para pesquisa e desenvolvimento farmacêutico.
Foram encontrados 4949 produtos de "Esteroides e Derivados"
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LANOSTEROL
CAS:<p>Lanosterol (3β-Hydroxy-8,24-lanostadiene) is a tetracyclic triterpenoid which is the compound from which all steroids are derived.</p>Fórmula:C30H50OPureza:97.99% - 99.67%Cor e Forma:SolidPeso molecular:426.72palovarotene
CAS:<p>Palovarotene (Ro 3300074) is an agonist of nuclear retinoic acid receptor γ (RAR-γ).</p>Fórmula:C27H30N2O2Pureza:97.88% - 98.05%Cor e Forma:SolidPeso molecular:414.54Levonorgestrel-d8 (D-(-)-Norgestrel-d8, Etonogestrel EP Impurity G-d8)
Fórmula:C21H20D8O2Peso molecular:320.50Stigmasterol
CAS:<p>Stigmasterol (Stigmasterin) is a phytosterol with a function in the maintenance of cell membranes. Stigmasterol lowers cholesterol levels. Cost-effective and quality-assured.</p>Fórmula:C29H48OPureza:99.67% - 99.97%Cor e Forma:White SolidPeso molecular:412.69Estradiol dipropionate
CAS:<p>Estradiol dipropionate (17-Beta-Estradiol-3,17-Dipropionate) is a synthetic ester, specifically the 3, 17-dipropanoyl ester, of the natural estrogen, estradiol.</p>Fórmula:C24H32O4Pureza:99.68%Cor e Forma:SolidPeso molecular:384.51Rosuvastatin
CAS:<p>Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.</p>Fórmula:C22H28FN3O6SPureza:95.24% - 99.8%Cor e Forma:SolidPeso molecular:481.54Ulipristal
CAS:<p>Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.</p>Fórmula:C28H35NO3Pureza:99.82%Cor e Forma:SolidPeso molecular:433.58Fluocinolone Acetonide 21-O-Sulfate Triethylamine Salt
CAS:Fórmula:C24H30F2O9S·C6H15NPeso molecular:532.55 101.19Hexestrol
CAS:<p>Hexestrol (Hexanoestrol) binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.</p>Fórmula:C18H22O2Pureza:98.93% - 99.2%Cor e Forma:Needles From Benzene Thin Plates From Dil Alc Crystalline SolidPeso molecular:270.37Fadrozole hydrochloride
CAS:<p>Fadrozole hydrochloride (CGS 16949A) is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish.</p>Fórmula:C14H14ClN3Pureza:≥95%Cor e Forma:SolidPeso molecular:259.73Medroxyprogesterone
CAS:<p>Medroxyprogesterone is used in the treatment of renal carcinoma. It is a synthetic progestational hormone used in veterinary practice as an estrus regulator.</p>Fórmula:C22H32O3Pureza:99.18% - 99.51%Cor e Forma:Crystals From Chloroform SolidPeso molecular:344.49Desoximetasone
CAS:<p>Desoximetasone (Topicort) is a topical corticosteroid for treating skin conditions like rashes.</p>Fórmula:C22H29FO4Pureza:99.06% - 99.89%Cor e Forma:SolidPeso molecular:376.46Lasofoxifene
CAS:<p>Lasofoxifene (CP-336156) is a selective oestrogen receptor modulator/antagonist that reduces serum IL-6 levels and inhibits joint inflammation and osteoporosis.</p>Fórmula:C28H31NO2Pureza:99.6%Cor e Forma:SolidPeso molecular:413.55Guggulsterone
CAS:<p>Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.</p>Fórmula:C21H28O2Pureza:99.4% - 99.8%Cor e Forma:Light Yellow PowderPeso molecular:312.45Fluprednisolone
CAS:<p>Fluprednisolone (NSC-47439) is a synthetic glucocorticoid that has anti-inflammatory properties.</p>Fórmula:C21H27FO5Pureza:98.44%Cor e Forma:White To Off-White Powder SolidPeso molecular:378.43Pinostrobin
CAS:<p>Pinostrobin protects PC12 cells from Aβ25-35 neurotoxicity by reducing oxidative stress, calcium excess, and blocking cell death pathways.</p>Fórmula:C16H14O4Pureza:99.35% - 99.55%Cor e Forma:SolidPeso molecular:270.2817,21-Dihydroxy-16a-methylpregna-1,4,9(11)-triene-3,20-dione 21-Acetate
CAS:Produto Controlado<p>Applications 17,21-Dihydroxy-16α-methylpregna-1,4,9(11)-triene-3,20-dione 21-Acetate is an intermediate in the synthesis of Mometasone Furoate (M490000), a tropical corticosteroid used as an anti-inflammatory agent.<br>References Spangler, M., et al.: Chromatograph., 54, 329 (2001); Reeves, E.K., et al.: Bioorg. Med. Chem., 21, 2241 (2013);<br></p>Fórmula:C24H30O5Cor e Forma:White To Light YellowPeso molecular:398.49Testosterone-2,2,4,6,6-d5
CAS:Produto ControladoFórmula:C192H5H23O2Cor e Forma:White To Off-WhitePeso molecular:293.464-Hydroxy Estradiol 1-N7-Guanine
CAS:Produto Controlado<p>Applications 4-Hydroxy Estradiol 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Fórmula:C23H27N5O4Cor e Forma:NeatPeso molecular:437.4916α-Methyl-11-oxo Prednisolone
CAS:Produto Controlado<p>Applications A 16α-substituted Prednisolone as potent topical antiinflammatory agent.<br>References Lutsky, B.N., et al.: Arzneim.-Forsch., 29, 1662 (1979),<br></p>Fórmula:C22H28O5Cor e Forma:White SolidPeso molecular:372.455β-Dihydro Progesterone-d8
CAS:Produto Controlado<p>Applications 5β-Dihydro Progesterone-d8 is labelled which is labelled 5β-Dihydro Progesterone (D449280), a metabolite of the neuroactive steroid Progesterone (PROG) (P755900).<br>References Wiebe, J., et al.: Cancer Res., 60, 936 (2000), Lacasa, D., et al.: J. Biol. Chem., 276, 11512 (2001), Johansson, I., et al.: Brain Res., 934, 125 (2002), Leonhardt, S., et al.: Steroids, 68, 761 (2003),<br></p>Fórmula:C21H24D8O2Cor e Forma:NeatPeso molecular:324.53Dexamethasone Sodium Phosphate Impurity C
<p>Applications Dexamethasone Sodium Phosphate Impurity C is a derivative of Dexamethasone Sodium Phospahte, which is an impurity compound of Dexamethasone (D298800). Dexamethasone regulates T cell survival, growth, and differentiation. it also inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Fórmula:C22H29FO5Cor e Forma:NeatPeso molecular:392.461Testosterone Enol Diacetate
CAS:Produto Controlado<p>Applications Controlled substance.<br></p>Fórmula:C23H32O4Cor e Forma:NeatPeso molecular:372.5Digitoxin-21,23,23-d3
CAS:Produto Controlado<p>Applications Isotope labelled Digitoxin (D445950), is used as a cardiotonic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Foerster, et al.: Arch. Int. Pharmacodyn. Ther., 159, 1 (1966), Jakovljevic, I.M., Anal. Profiles Drug Subs., 3, 149 (1974)<br></p>Fórmula:C41H61D3O13Pureza:90%Cor e Forma:NeatPeso molecular:767.965-Oxo Atorvastatin
CAS:<p>Applications Atorvastatin Derivative<br></p>Fórmula:C33H33FN2O5Cor e Forma:NeatPeso molecular:556.62Digitoxin
CAS:<p>Stability Hygroscopic<br>Applications Cardiotonic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Foerster, et al.: Arch. Int. Pharmacodyn. Ther., 159, 1 (1966), Jakovljevic, I.M., Anal. Profiles Drug Subs., 3, 149 (1974)<br></p>Fórmula:C41H64O13Cor e Forma:White To Off-WhitePeso molecular:764.9417-Hydroxy-3,11-dioxo-androsta-1,4-diene-17β-carboxylic Acid
Produto Controlado<p>Applications 17-Hydroxy-3,11-dioxo-androsta-1,4-diene-17β-carboxylic Acid is an intermediate used to prepare (11β,17α)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-androsta-1,4-diene-17-carboxylic acid (E890570) which is a derivative of Loteprednol Etabonate (L471400), an ophthalmic corticosteroid.<br>References Alberth, M., et al.: J. Biopharm.Sci., 2, 115 (1991), Bodor, N., et al.: Pharm. Res., 9, 1275 (1992), Bartlett, J.D., et al.: J. Ocul. Pharmacol., 9, 157 (1993)<br></p>Fórmula:C20H24O5Cor e Forma:NeatPeso molecular:344.4017β-Estradiol
CAS:Produto Controlado<p>Impurity Ethinylestradiol EP Impurity D<br>Applications 17b-Estradiol is the major estrogen (1) secreted by the premenopausal ovary (2).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Salole, E. et al.: Anal. Profiles Drug Subs. 1986 15, 23 283-3182. Lievertz, R. et al.: Am. J. Obstet. Gynecol. 1987 May;156(5):1289-93.<br></p>Fórmula:C18H24O2Cor e Forma:NeatPeso molecular:272.38Testosterone 17-Isobutyrate
CAS:Produto Controlado<p>Applications Testosterone ester.<br>References Zarzycki, P., et al.: Anal. Bioanal. Chem., 391, 2219 (2008), Talarovicova, A., et al.: Hormon. Behav., 55, 235 (2009),<br></p>Fórmula:C23H34O3Cor e Forma:Off-WhitePeso molecular:358.51Flurandrenolide
CAS:Produto Controlado<p>Applications Glucocorticoid; antipsoriatic.<br>References Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984), Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),<br></p>Fórmula:C24H33FO6Cor e Forma:NeatPeso molecular:436.51Hydroxy Flutamide-d6
CAS:Produto ControladoFórmula:C11H5D6F3N2O4Cor e Forma:Light Yellow SolidPeso molecular:298.254-Hydroxy Atorvastatin-d5 Hemicalcium Salt
CAS:Produto Controlado<p>Applications di(4-Hydroxy Atorvastatin-d5) Calcium Salt is a labeled metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Fórmula:C66H58D10CaF2N4O12Cor e Forma:Beige SolidPeso molecular:1197.4β-Methyl Digoxin
CAS:<p>Applications Cardiotonic. Obtained by the O-methylation of Digoxin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hunter, J., et al.: J. Biol. Chem., 268, 14991 (1993), Greiner, B., et al.: J. Clin. Invest., 104, 147 (1999), Jun, A., et al.: J. Pharm.Pharm. Sci., 4, 263 (2001), Sugiyama, D., et al.: Drug Metab. Dispos., 30, 220 (2002),<br></p>Fórmula:C42H66O14Cor e Forma:NeatPeso molecular:794.9716-Epiestriol, Ultra Pure (contains less than 0.3% Estriol)
CAS:Produto ControladoFórmula:C18H24O3Cor e Forma:NeatPeso molecular:288.38Cyproterone-d4
CAS:Produto Controlado<p>Applications Labelled Cyproterone (C989090). An antiandrogen, suppresses Testosterone and its metabolites. Derivatives of Cyproterone are administered to patients suffering from hypersexuality and to help facilitate the sexual transformation of male-to-female transsexuals.<br>References Gracia, T., et al.: Toxicol. App. Pharmacol., 225, 142 (2007), Ahlin, G., et al.: J. Med. Chem., 51, 5932 (2008), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Bovee, T., et al.: J. Steroid Biochem. Mol. Biol., 118, 85 (2010),<br></p>Fórmula:C22H23D4ClO3Cor e Forma:NeatPeso molecular:378.93Oleandrin
CAS:<p>Applications Cardiotonic; diuretic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sreenivasan, Y., et al.: Biochem. Pharmacol., 66, 2223 (2003), Ni, D., et al.: J. Exp. Ther. Oncol., 2, 278 (2002), Langford, S.D., Toxicology, 109,1 (1996),<br></p>Fórmula:C32H48O9Cor e Forma:White To Off-WhitePeso molecular:576.723β-Hydroxy Tibolone
CAS:Produto Controlado<p>Applications A metabolite of Tibolone. A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.<br>References Belman, S., et al.: Cancer Res., 32, 450 (1972), Shirahashi, H., et al.: Chem. Pharm. Bull., 41, 1664 (1993), Hoyte, R., et al.: Steroids, 58, 13 (1993), Sandker, G., et al.: Xenobiotica, 24, 143 (1994), Colombo, D., et al.: Eur. J. Med. Chem., 40, 69 (2005),<br></p>Fórmula:C21H30O2Cor e Forma:White To Off-WhitePeso molecular:314.46Tibolone
CAS:Produto Controlado<p>Applications A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.<br>References de Visser, J., et al.: Arzneim.-Forsch., 34, 1010 (1984), Geusens, P., et al.: Maturitas Suppl, 1, 1 (1987)<br></p>Fórmula:C21H28O2Cor e Forma:WhitePeso molecular:312.456α-Methyl-9α-fluoro-11β,17α-dihydroxyprogesterone
CAS:Produto Controlado<p>Applications 6α-Methyl-9α-fluoro-11β,17α-dihydroxyprogesterone is an impurity of Fluorometholone (F593145), a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982), Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984),<br></p>Fórmula:C22H31FO4Cor e Forma:NeatPeso molecular:378.48Bexarotene
CAS:Produto Controlado<p>Applications Bexarotene is a selective retinoid X receptor (RXR) agonist and an antineoplastic agent (1,2,3).<br>References (1) Boehm, M.F., et al.: J. Med. Che., 37,2930 (1994) (2) Gottardis, M.M., et al.: Cancer Res., 56, 5566 (1996) (3) Mukherjee, R., et al.: Nature, 386, 407 (1997)<br></p>Fórmula:C24H28O2Cor e Forma:NeatPeso molecular:348.48Testosterone Octanoate
CAS:Produto Controlado<p>Applications Testosterone Octanoate is a metabolite of testosterone (T155000), which is used in biological studies to determine the hemolytic and lipophilic activity of this anabolic steroid.<br>References Biagi, G.L., et al.: J. Med. Chem., 13, 944 (1970); Biagi, G. L., et al.: J. Med. Chem., 18, 873 (1975)<br></p>Fórmula:C27H42O3Cor e Forma:NeatPeso molecular:414.6215β-Dihydrocortisone Acetate 21-Acetate
CAS:Produto Controlado<p>Applications Cortisone (C696500) derivative.<br></p>Fórmula:C23H32O6Cor e Forma:NeatPeso molecular:404.5(17a)-3-Ethynyl-19-norpregna-3,5-dien-20-yn-17-ol
CAS:<p>Impurity Norethindrone EP Impurity E<br>Applications (17α)-3-Ethynyl-19-norpregna-3,5-dien-20-yn-17-ol (Norethindrone EP Impurity E) is an impurity of Norethindrone (N676000).<br></p>Fórmula:C22H26OCor e Forma:NeatPeso molecular:306.44Eplerenone 7-Carboxylic Acid
CAS:<p>Applications Eplerenone 7-Carboxylic Acid is an impurity of Eplerenone (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.<br>References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),<br></p>Fórmula:C23H28O6Cor e Forma:Off-White To Light YellowPeso molecular:400.46Betamethasone 17-Butyrate
CAS:Produto Controlado<p>Applications Betamethasone 17-Butyrate is an impurity of Clobetasone 17-Butyrate (C583550), an glucocorticoid used for anti-inflammatory purposes.<br></p>Fórmula:C26H35FO6Cor e Forma:NeatPeso molecular:462.55Tetrahydrocortisol
CAS:Produto Controlado<p>Applications Tetrahydrocortisol is excreted in large amounts in premenopausal patients with early breast cancer. Tetrahydrocortisol has been found to be produced by lymphocytes in both normal and cancer bearing patients however, the concentration of Tetrahydrocortisol has increased in patients with cancer.<br>References Kodama, M., et. al.: J. Natl. Cancer I., 54, 1275 (1975); Klein, A., et. al.: Metabolism, 27, 731 (1978)<br></p>Fórmula:C21H34O5Cor e Forma:Off-WhitePeso molecular:366.496-Bromo-betamethasone 17,21-Dipropionate
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 6-Bromo-Betamethasone 17,21-Dipropionate (Betamethasone Dipropionate EP Impurity H) is an impurity of Betamethasone (B327000), a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977); Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002); Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005)<br></p>Fórmula:C28H36BrFO7Cor e Forma:NeatPeso molecular:583.482-Hydroxymethylene Ethisterone
CAS:Produto Controlado<p>Applications A derivative of Danazol (D145000).<br>References Manson, A.J., et al.: J. Med. Chem., 6, 1 (1963), Jordan, V.C., et al.: Endocrinology, 124, 1717 (1989),<br></p>Fórmula:C22H28O3Cor e Forma:NeatPeso molecular:340.4616a-Hydroxy Progesterone
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 16α-Hydroxyprrogesterone is a hydroxylated metabolite of Progesterone (P755900). 16α-Hydroxyprogesterone binds to human progesterone receptors hPR-A and hPR-B and act as an agonist for both receptors.<br>References Ikonen, M. et al.: Nature, 212, 716 (1966); Storbeck, K.-H. et al.: Mol. Cell. Endocrinol., 336, 92 (2011);<br></p>Fórmula:C21H30O3Cor e Forma:Off-WhitePeso molecular:330.46Testosterone Undecylenate
CAS:Produto Controlado<p>Applications Testosterone Undecylenate is an ester metabolite of Testosterone (T155000), which is the main hormone of the testes, produced by the interstitial cells. It is a major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone that is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.<br>References McFarland, K., et al.: Science, 245, 494 (1989); Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998); Themmen, A., et al.: Endocr. Rev. 21, 551 (2000); Kumar, R., et al.: Biol. Reprod., 65, 710 (2001);<br></p>Fórmula:C30H46O3Cor e Forma:NeatPeso molecular:454.68421-Dehydro Dexamethasone Hydrate
CAS:Fórmula:C22H27FO5·H2OCor e Forma:White To Light YellowPeso molecular:408.46Difluprednate
CAS:Produto Controlado<p>Applications A corticosteroid (derivative of prednisolone), approved for the treatment of post-operative ocular inflammation.<br>References Kapp, A., et al.: J. Allergy and Clin. Immunol., 110, 277 (2002), Yasueda, S., et al.: J. Pharm. Biomed. Anal., 30, 1735 (2003), Yamaguchi, M., et al.: Int. J. Pharm., 301, 121 (2005),<br></p>Fórmula:C27H34F2O7Cor e Forma:WhitePeso molecular:508.5517-Iodo-androsta-5,16-diene-3β-ol
CAS:Produto Controlado<p>Impurity Abiraterone Impurity 5<br>Applications 17-Iodo-androsta-5,16-diene-3β-ol is an analog of Abiraterone (A108490) and is used as a reagent in the synthesis of C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens which exhibit antitumor activity. Abiraterone Impurity 5<br>References Handratta, V.D., et al.: J. Med. Chem., 48, 2972 (2005)<br></p>Fórmula:C19H27IOCor e Forma:White To Off-WhitePeso molecular:398.32Exemestane
CAS:Produto Controlado<p>Applications Exemestane is an antineoplastic (hormonal).<br>References Giudici, D., et al.: J. Steroid Biochem., 30, 391 (1988), Evans, T.R.J., et al.: Cancer Res., 52, 5933 (1992), Zilembo, N., et al.: Brit. J. Cancer, 72, 1007 (1995)<br></p>Fórmula:C20H24O2Cor e Forma:White To Light GreenPeso molecular:296.40Estradiol 17β-sulfate
CAS:Produto Controlado<p>Applications Estradiol 17β-sulfate is a naturally occuring steroid in whihc can be converted into Estradiol(E888000)<br>References Takanashi, K., et al.: Steroids., 68, 383-392 (2003)<br></p>Fórmula:C18H24O5SPureza:>90%Cor e Forma:NeatPeso molecular:352.45Medroxy Progesterone
CAS:Produto Controlado<p>Impurity Medroxyprogesterone Acetate USP Related Compound B<br>Applications An orally active progestogen used in hormone replacement therepy (HRT), in the past has been used as a component of oral contraceptives.SMedroxyprogesterone Acetate USP Related Compound B.<br>References Pan, Q., et al.: Mol. Hum. Reprod., 13, 797 (2007), Matsson, P., et al.: J. Pharmacol. Exp. Ther., 323, 19 (2007), Jukosky, J.A., et al.: Bull. Environ. Contam. Toxicol., 81, 230 (2008), Cherkasov, A., et al.: J. Med. Chem., 51, 2047 (2008),<br></p>Fórmula:C22H32O3Cor e Forma:NeatPeso molecular:344.494-Pregnen-17α,20β-diol-3-one
CAS:<p>Stability Store in Freezer<br>Applications 4-Pregnen-17α,20β-diol-3-one (cas# 1662-06-2) is a compound useful in organic synthesis.<br></p>Fórmula:C21H32O3Cor e Forma:White To Light YellowPeso molecular:332.48Dexamethasone 9,11-Epoxide-d5
CAS:Produto Controlado<p>Applications Dexamethasone 9,11-Epoxide-d5, is the labeled analogue of the unlabeled (D298795 ), a Dexamethasone intermediate.<br>References Isogai, M., et al.: J. Steroid Biochem. Mol. Biol., 44, 141 (1993),<br></p>Fórmula:C22H23D5O5Cor e Forma:Off-WhitePeso molecular:377.49δ4-Pregnen-20α-ol-3-one
CAS:Produto Controlado<p>Impurity Progesterone EP Impurity B<br>Applications Δ4-Pregnen-20α-ol-3-one (Progesterone EP Impurity B) is the main metabolite of Progesterone (P755900). Studies shows regulation of estrogen receptor levels in breast cancer by Δ4-Pregnen-20α-ol-3-one and other progesterone metabolites.<br>References Zhang, L. et al.: Yaoz. Xueb., 39, 613 (2004); Pawlak, K.J. et al.: J. Steroid. Biochem. Mol. Biol., 107, 172 (2007);<br></p>Fórmula:C21H32O2Cor e Forma:Off White SolidPeso molecular:316.4817β-Dihydro Equilin
CAS:<p>Applications A metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Fórmula:C18H22O2Cor e Forma:NeatPeso molecular:270.37Danazol
CAS:Produto Controlado<p>Applications Danazol is an anterior pituitary supressant. Danazol is an anabolic steroid derivative of ethisterone, with mild androgenic side effects (an impeded androgen). Antigonadotropin.<br>References Ahn, Y.S., et al.: N. Engl. J. Med., 308, 1396 (1983),<br></p>Fórmula:C22H27NO2Cor e Forma:White To Light YellowPeso molecular:337.463-O-Methyl Estrone
CAS:Produto ControladoFórmula:C19H24O2Cor e Forma:White To Dark BrownPeso molecular:284.3917-epi-Norethindrone
CAS:Produto Controlado<p>Impurity Norethindrone EP Impurity G<br>Applications Norethindrone (N676000) epimer. Norethindrone and acetate is used in combination with estrogen as contraceptive (oral). Norethindrone EP Impurity G.<br>References Angel, P., et al.: Biochim. Biophys. Acta., 1072, 129 (1991), Chenu, C., et al.: J. Cell Biol., 127, 1149 (1994), Schmidt, M., et al.: J. Endocrinol., 158, 401 (1998),<br></p>Fórmula:C20H26O2Cor e Forma:Off White SolidPeso molecular:298.4214,15-Dehydro Budesonide
CAS:Produto Controlado<p>Impurity Budesonide EP Impurity E<br>Applications 14,15-Dehydro Budesonide (Budesonide EP Impurity E) is a Budesonide (B689490) impurity.<br>References Aherne, G., et al.: J. Steroid Biochem., 17, 559 (1982), Assi, K., et al.: J. Pharm. Biomed. Anal., 41, 325 (2006),<br></p>Fórmula:C25H32O6Cor e Forma:WhitePeso molecular:428.518a-Acetyl Digoxin
CAS:Produto Controlado<p>Applications Digoxin derivative, a cardiotonic glycosides steroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yoshida, F., et al.: J. Med. Chem., 43, 2575 ( 2000), Turner, J., et al.: Pharm. Res., 21, 68 (2004), Wang, J., et al.: Anal. Chim. Acta, 601, 156 (2007),<br></p>Fórmula:C43H66O15Cor e Forma:NeatPeso molecular:822.9816a,17-[(1RS)-Butylidenebis(oxy)]-11b-hydroxy-17-(hydroxymethyl)-D-homoandrosta-1,4-diene-3,17a-dione (Mixture of Diastereomers)
CAS:Produto Controlado<p>Impurity Budesonide EP Impurity C, Budesonide Impurity C,<br>Applications 16α,17-[(1RS)-butylidenebis(oxy)]-11β-hydroxy-17-(hydroxymethyl)-D-homoandrosta-1,4-diene-3,17a-dione (Budesonide EP Impurity C) is an impurity of Budesonide (B689490), an antiinflammatory agent.<br>References Ferraboschi, P. et al.: J. Pharm. Biomed. Anal., 47, 636 (2008);<br></p>Fórmula:C25H34O6Cor e Forma:WhitePeso molecular:430.533α,5β-Tetrahydro Norgestrel
CAS:Produto Controlado<p>Applications The major metabolite of the progestational agent Norgestrel (N689500).<br>References DeJongh, D.C. et al.: Steroids, 11, 649 (1968); Uniyal, J.P. et al.: Acta Endocrinol., 84, 155 (1977); Sisenwine, S.F. et al.: Drug Metab. Disp., 7, 1 (1979);<br></p>Fórmula:C21H32O2Cor e Forma:NeatPeso molecular:316.48Norgestimate
CAS:Produto Controlado<p>Applications Progestogen. In combination with estrogen as oral contraceptive.<br>References Hahn, D.W., et al.: Contraception, 16, 541 (1977), Weintraub, H.S., et al.: J. Pharm. Sci., 67, 1406 (1978),<br></p>Fórmula:C23H31NO3Cor e Forma:White SolidPeso molecular:369.507β-Hydroxy Cholesterol
CAS:Produto Controlado<p>Applications A metabolite of Cholesterol. Its membrane organizing properties could have implications in Altzheimer’s disease.<br>References Wang, J., et al.: Biochemistry, 43, 1010 (2004), Lemaire-Ewing, S., et al.: Cell Biol. Toxicol., 21, 97 (2005), Fuda, H., et al.: J. Lipid Res., 48, 1343 ( 2007), Sasaki, H., et al.: Metabolism, 56, 357 (2007); S.L. Regen et al.: J. Amer. Chem. Soc., 131, 12354 (2009)<br></p>Fórmula:C27H46O2Cor e Forma:NeatPeso molecular:402.65(7α,17α)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Di-γ-lactone
CAS:Produto Controlado<p>Applications (7α,17α)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Di-γ-lactone is an eplerenone (E588775) impurity. Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.<br>References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),<br></p>Fórmula:C23H28O5Cor e Forma:NeatPeso molecular:384.47E,E-Dienestrol-d6
Produto ControladoFórmula:C18H12D6O2Cor e Forma:Light Beige To BrownPeso molecular:272.37(3a)-Allopregnanolone Sulfate Pyridinium Salt
CAS:Produto Controlado<p>Applications (3α)-Allopregnanolone Sulfate is the sulfate conjugate of (3α)-Allopregnanolone (A547100), a metabolite of progesterone and potent positive modulator of GABAA receptors.<br>References El-Etr, M. et al.: Brain Res., 790, 334 (1998); Hauser, C.A.E. et al.: Eur. J. Pharmacol. Mol. Pharmacol. Sec., 289, 249 (1995);<br></p>Fórmula:C26H39NO5SCor e Forma:White To Off-WhitePeso molecular:477.66Isoflupredone-d3 (d2 Major)
CAS:Produto Controlado<p>Applications Labelled Isoflupredone (I816600). Anti-inflammatory.<br>References Buchwald, P., et al.: Steroids, 73, 193 (2008), Holbeck, S., et al.: Mol. Endocrinol., 24, 1287 (2010),<br></p>Fórmula:C21H24D3FO5Cor e Forma:NeatPeso molecular:381.4517β-Estradiol-16,16,17-d3
CAS:Produto Controlado<p>Applications Isotope labelled 17β-Estradiol (E888000), which is the major estrogen (1) secreted by the premenopausal ovary (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Salole, E. et al.: Anal. Profiles Drug Subs. 1986 15, 23 283-3182. Lievertz, R. et al.: Am. J. Obstet. Gynecol. 1987 May;156(5):1289-93.<br></p>Fórmula:C182H3H21O2Cor e Forma:NeatPeso molecular:275.40Triamcinolone Hexacetonide
CAS:Produto Controlado<p>Applications Triamcinolone Hexacetonide is the Intra-articular glucocorticoid treatment for rheumatoid arthritis.<br>References Abd-El-Barr, M.M., et al.: J. Ocul. Pharmacol. Ther., 24, 197 (2007); Eberhard, B.A., et al.: J. Rheumatol., 31, 2507 (2004);<br></p>Fórmula:C30H41FO7Cor e Forma:WhitePeso molecular:532.64Latanoprost Acid-d4(>85%)
CAS:Produto Controlado<p>Applications Latanoprost Acid-d4 is the labeled analogue of Latanoprost Acid (L177310), a metabolite of Latanoprost. Latanoprost Acid (L177310) is a potent, selective FP prostanoid receptor agonist, a F-series Prostaglandin analog and is 200 times as potent as isopropyl ester form.<br>References Sjoquist, B., et al.: Drug Metab. Dispos., 26, 745 (1998), Watson, P., et al.: Drugs Today, 35, 449 (1999), Kashiwagi, K., et al.: Exp. Eye Res., 74, 41 (2002),<br></p>Fórmula:C23H30D4O5Pureza:>85%Cor e Forma:ColourlessPeso molecular:394.542-Nitrobenzotrifluoride
CAS:Produto Controlado<p>Applications 2-Nitrobenzotrifluoride can be used for self-repairing polyimide based on dynamic imine bond.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lei, X., et.al., Faming Zhuanli Shenqing, 15, (2019);<br></p>Fórmula:C7H4F3NO2Cor e Forma:NeatPeso molecular:191.107Testosterone Enanthate-d3
CAS:Produto Controlado<p>Applications Isotope labelled testosterone enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.<br>References Janjic, M.M., et al.: Reproduct. Toxicol., 34, 686 (2012); Lacreuse, A., et al.: Physiol. Behaviour., 106, 229 (2012);<br></p>Fórmula:C26H37D3O3Cor e Forma:Colourless To Off-WhitePeso molecular:403.61Secalciferol
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications A metabolite of Vitamin D, a possibly anti-inflammatory steroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Boyan, B., et al.: Steroids, 66, 363 (2001), Holick, M., et al.: J. Cell Biochem., 88, 296 (2003), Vogeser, M., et al.: Clin. Chem., 50, 1415 (2004), Singh, R., et al.: J. Clin. Endocrinol. Metab., 91, 3055 (2006),<br></p>Fórmula:C27H44O3Cor e Forma:NeatPeso molecular:416.641,2-Dihydro-deflazacort
CAS:Produto ControladoFórmula:C25H33NO6Cor e Forma:NeatPeso molecular:443.533Cholesterol 3-Acetate-d7
CAS:Produto ControladoFórmula:C29H41D7O2Cor e Forma:NeatPeso molecular:435.73Clobetasol Propionate Impurity E
<p>Applications Clobetasol Propionate Impurity E is an impurity of Clobetasol (C583490), which is a topical corticosteroid. Glucocorticoid; anti-inflammatory.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),<br></p>Fórmula:C25H33ClO4Cor e Forma:NeatPeso molecular:432.98Δ-5(10)-Norethindrone Acetate
CAS:Produto Controlado<p>Impurity Norethindrone Acetate EP Impurity B<br>Applications Δ-5(10)-Norethindrone Acetate (Norethindrone Acetate EP Impurity B) is a Norethindrone Acetate (N675990) impurity. Used in studies of progesterone-binding properties of purified uteroglobin-like protein.<br>References Beato, M. et al.: J. Reprod. Fert., 53, 305 (1978); Schroff, A. P., et al.: Anal. Profiles Drug Subs., 4, 268 (1975); Singh, H., et al.: Am. J. Obstet. Gynecol., 135, 409 (1979);<br></p>Fórmula:C22H28O3Cor e Forma:Off-WhitePeso molecular:340.46Betamethasone 21-O-Ethyl Carbonate
CAS:Produto Controlado<p>Impurity Betamethasone EP Impurity D<br>Applications Betamethasone 21-O-Ethyl Carbonate (Betamethasone EP Impurity D) is a derivative of Betamethasone (B327000); a glucocorticoid used as an anti-inflammatory agent.4<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977); Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002); Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005); Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006); Xiong, Y., et al.: J. Pharmaceut. Biomed., 49, 646 (2009)<br></p>Fórmula:C25H33FO7Cor e Forma:NeatPeso molecular:464.52Fulvestrant-d3
CAS:Produto ControladoFórmula:C32H44D3F5O3SCor e Forma:White To Off-WhitePeso molecular:609.79Dienogest-d8 (major)
CAS:Produto Controlado<p>Applications Dienogest-d8 (major) is labelled derivative of 19-Nortestosterone. It is used in combination with estrogen as oral contraceptive.<br>References Hubner, M., et al.: Arzneim.-Forsch., 30, 401 (1980), Spona, J., et al.: Contraception, 56, 185 (1997), Foster, R.H., et al.: Drugs, 56, 825 (1998)<br></p>Fórmula:C20H17D8NO2Cor e Forma:Light YellowPeso molecular:319.47Paricalcitol
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Synthetic analog of vitamin D. Antihyperparathyroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sidek, H., et al.: Biochim. Biophys. Acta, 801, 26 (1984), Ciftci, M., et al.: J. Pharmacol., 54, 275 (2002),<br></p>Fórmula:C27H44O3Cor e Forma:NeatPeso molecular:416.64Testosterone Sulfate-d3 Triethylamine Salt
CAS:Produto Controlado<p>Applications The labelled analogue of a metabolite of Testosterone (T155000). It is a urinary metabolite of Androstenedione (A637550) in patients with Addison's disease and also used as a marker in blood plasma for detection of prostate cancer.<br>References Lokhov, P.G. et al.: Metabolomics, 6, 156 (2010); Bonnaire, Y. et al.: J. Anal. Toxicol., 19, 175 (1995); Tamm, J. et al.: Steroids, 8, 659 (1966);<br></p>Fórmula:C25H40D3NO5SCor e Forma:Off-WhitePeso molecular:472.7Estradiol Enanthate
CAS:<p>Applications Estradiol Enanthate has been used as an injectable contraceptive.<br>References Coutinho, E.M., et. al.: Contraception, 73, 249 (2006)<br></p>Fórmula:C25H36O3Cor e Forma:BeigePeso molecular:384.555(6)-Dehydro-4(5)-dihydro D-(-)-Norgestrel (>90%)
CAS:Produto Controlado<p>Impurity Levonorgestrel EP Impurity P<br>Applications 5(6)-Dehydro-4(5)-dihydro D-(-)-Norgestrel (Levonorgestrel EP Impurity P) is a Norgestrel (N689500) impurity.<br></p>Fórmula:C21H28O2Pureza:>90%Cor e Forma:NeatPeso molecular:312.456-Ketoprogesterone
CAS:Produto Controlado<p>Applications 6-Ketoprogesterone is used in the synthesis and biological evaluation of steroidal deivatives as selective inhibitors of AKR1B10. AKR1B10 is a promising anti-cancer therapeutic target.<br>References Zhang, W., et al.: Steroids, 86, 39 (2014)<br></p>Fórmula:C21H28O3Cor e Forma:NeatPeso molecular:328.4517β-Estradiol-d3 17-Acetate
CAS:Produto Controlado<p>Applications Protected Estradiol.<br>References Miilunpohja, M., et al.: J. Steroid Biochem. Mol. Biol., 100, 59 (2006), Ikonomou, M., et al.: Environ. Toxicol. Chem., 27, 243 (2008),<br></p>Fórmula:C20H23D3O3Cor e Forma:NeatPeso molecular:317.441-Chloro Dihydro Dutasteride
CAS:<p>Impurity Dutasteride EP Impurity F<br>Applications 1-Chloro Dihydro Dutasteride (Dutateride EP Impurity F) is a 3-oxo-4-aza-5α-androstene-17β-carboxylic acid derivative and an impurity of Dutasteride (D735000).<br></p>Fórmula:C27H31ClF6N2O2Cor e Forma:NeatPeso molecular:564.9917α-Dutasteride
CAS:Produto Controlado<p>Impurity Dutateride EP Impurity E<br>Applications 17α-Dutasteride (Dutateride EP Impurity E) is an impurity of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000).<br></p>Fórmula:C27H30F6N2O2Cor e Forma:Dark Orange Colour SolidPeso molecular:528.53Norethindrone-d7 (Major)
CAS:Produto ControladoFórmula:C20H19D7O2Cor e Forma:NeatPeso molecular:305.464-Hydroxy Estrone
CAS:Produto ControladoFórmula:C18H22O3Cor e Forma:Light Brown SolidPeso molecular:286.37Estradiol-13C2 17-Benzoate
CAS:<p>Applications Estradiol-13C2 17-Benzoate is an intermediate in the synthesis of 17β-Estradiol-13C2 (E888003). Isotope labelled 17β-Estradiol (E888000) is the major estrogen (1) secreted by the premenopausal ovary (2).<br></p>Fórmula:C2313C2H28O3Pureza:>90%Cor e Forma:NeatPeso molecular:378.47Fluocinolone Acetonide-21-aldehyde
CAS:<p>Impurity Fluocinolone Acetonide EP Impurity D<br>Stability Hygroscopic<br>Applications Fluocinolone acetonide-21-aldehyde, is a derivative of Fluocinolone Acetonide (F455800), which is a Corticosteroid, used in dermatology to reduce skin inflammation and relieve itching.<br>References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),<br></p>Fórmula:C24H28F2O6Cor e Forma:White To Light YellowPeso molecular:450.47Spironolactone
CAS:Produto Controlado<p>Applications It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome.<br>References Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975),<br></p>Fórmula:C24H32O4SCor e Forma:Off-WhitePeso molecular:416.577α-Thiomethyl Spironolactone-d7 (Major)
CAS:Produto Controlado<p>Applications A labelled metabolite of Spironolactone.<br>References Gochman, N., et al.: J. Pharmacol. Exp. Ther., 135, 312 (1962), Tori, K., et al.: Steroids, 4, 713 (1964), Solymoss, B., et al.: Toxicol. Appli. Pharmacol., 18, 586 (1971),<br></p>Fórmula:C23H25D7O3SCor e Forma:NeatPeso molecular:395.617α-Hydroxy Cholesterol
CAS:Produto Controlado<p>Applications Secondary metabolite of Cholesterol.<br>References Notaro, G., et al.: J. Nat. Prod., 55, 1588 (1992), Aydogmus, Z., et al.: Nat. Prod. Res., 18, 43 (2004), Mao, S., et al.: J. Nat. Prod ., 69, 1209 (2006), Shoji, T., et al.: J. Agric. Food Chem., 54, 884 (2006),<br></p>Fórmula:C27H46O2Cor e Forma:Off-WhitePeso molecular:402.65Betamethasone 6α-Bromo 17-Valerate
Produto Controlado<p>Applications Betamethasone 6α-Bromo 17-Valerate is an impurity of Betamethasone (B327000), which is a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),<br></p>Fórmula:C27H36BrFO6Cor e Forma:NeatPeso molecular:555.479,11-Anhydrobudesonide(Mixture of Diastereomers)
CAS:Produto Controlado<p>Impurity Budesonide EP Impurity H<br>Applications 9,11-Anhydrobudesonide (Budesonide EP Impurity H) is an impurity of Budesonide (B689460), a non-halogenated glucocorticoid intended for the local treatment of lung disease.<br>References Ryrfeldt, Å., et al.: Eur. J. Respir. Dis., 122, 86 (1981); Vestbo, J., et al.: Lancet, 353, 1819 (1999)<br></p>Fórmula:C25H32O5Cor e Forma:NeatPeso molecular:412.524-Hydroxy Estrone 1-N7-Guanine
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-Hydroxy Estrone 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Fórmula:C23H25N5O4Cor e Forma:NeatPeso molecular:435.48Oxandrolone
CAS:Produto Controlado<p>Applications A synthetic, anabolic steroid. Used to promote muscle growth and combat involuntary weight loss. It has also been used to treat cases of osteoporosis.<br>References Cadwallader, A., et al.: Mol. Pharm., 7, 689 (2010), Amundson, E., et al.: J. Clin. Endocrinol. Metabol., 95, 1355 (2010), Bovee, T., et al.: J. Steroid Biochem. Mol. Biol., 118, 85 (2010), Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2010),<br></p>Fórmula:C19H30O3Cor e Forma:White To Off-WhitePeso molecular:306.44Testosterone Enanthate
CAS:Produto Controlado<p>Applications Testosterone Enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.<br>References Janjic, M.M., et al.: Reproduct. Toxicol., 34, 686 (2012); Lacreuse, A., et al.: Physiol. Behaviour., 106, 229 (2012);<br></p>Fórmula:C26H40O3Cor e Forma:Colourless To Off-WhitePeso molecular:400.594’-Hydroxy Dutasteride
Produto Controlado<p>Applications 4’-Hydroxy Dutasteride is an impurity of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Fórmula:C27H30F6N2O3Cor e Forma:NeatPeso molecular:544.53(7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester
CAS:<p>Applications (7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester is an impurity of eplerenone (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.<br>References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),<br></p>Fórmula:C24H30O6Cor e Forma:NeatPeso molecular:414.491N-Demethyl Mifepristone
CAS:<p>Applications A metabolite of Mifepristone (M343975).<br>References Ringler, I., et al.: Metabolism, 13, 37 (1964), Gagne, D., et al.: J. Steroid. Biochem., 25, 315 (1986), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Hild, S., et al.: Hum. Reprod., 15, 822 (2000), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Fórmula:C28H33NO2Cor e Forma:NeatPeso molecular:415.5725-Hydroxy Vitamin D3 3-Sulfate Sodium Salt (90%)
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 25-Hydroxyvitamin D3 3-Sulfate is a metabolite of 24,25-Dihydroxyvitamin D3 and 25-Hydroxyvitamin D3 (C125700).<br>References Higashi, T. et al.: Steroids, 65, 281 (2000); Higashi, T. et al.: Ann. Clin. Biochem., 36, 43 (1999);<br></p>Fórmula:C27H43NaO5SPureza:90%Cor e Forma:NeatPeso molecular:502.68Prednisolone 21-Methanesulfonate
CAS:Produto ControladoFórmula:C22H30O7SCor e Forma:NeatPeso molecular:438.5344-Methoxy Estrone-13C,d3
CAS:Produto Controlado<p>Applications Labelled 4-Methoxyestrone (M226135). An endogenous estrogen metabolite, risk-factor for development of breast cancer.<br>References Beral, V., et al.: Lancet, 362, 419 (2003), Nelson, R., et al.: Clin. Chem., 50, 373 (2004), Malekinejad, H., et al.: J. Agric. Food Chem., 54, 9785 (2006),<br></p>Fórmula:CC182H3H21O3Cor e Forma:Off-White To Light YellowPeso molecular:304.4017β-Estradiol-d3 17-Acetate 3-β-D-Glucuronide
Produto Controlado<p>Applications A labelled Estradiol (E888000) derivative.<br></p>Fórmula:C26H31D3O9Cor e Forma:NeatPeso molecular:493.564-Hydroxy Atorvastatin Disodium Salt
CAS:<p>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),<br></p>Fórmula:C33H33FN2Na2O6Cor e Forma:White To BrownPeso molecular:618.60Estradiol 3-Sulfate 17β-Glucuronide Dipotassium
CAS:Produto Controlado<p>Applications A 17β-Estradiol (E888000) metabolite.<br>References Gerk, P., et al.: Drug Metab. Disposition, 32, 1139 (2004), Antignac, J., et al.: Steroids, 70, 205 (2005), Cole, T., et al.: J. Fish Biol., 68, 661 (2006), Hutchins, S., et al.: Env. Sci. Technol., 41, 7192 (2007),<br></p>Fórmula:C24H30O11S·2KCor e Forma:White To Off-WhitePeso molecular:604.75(3β)-Cholesta-4,6-dien-3-ol
CAS:<p>Applications (3β)-Cholesta-4,6-dien-3-ol is a Cholesterol (C432501) and Cholestane (C431700) derivative which has the potential to act as an antiinflammatory and antifungal compound.<br>References Felicio, R. et al.: J. Pharm. Biomed. Anal., 52, 763 (2010); Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),<br></p>Fórmula:C27H44OCor e Forma:NeatPeso molecular:384.64δ7,9(11)-Dexamethasone
CAS:<p>Stability Hygroscopic<br>Applications Dexamethasone (D298800) process impurity.<br></p>Fórmula:C22H26O4Cor e Forma:NeatPeso molecular:354.443(R,S)-Hydroxy Desogestrel
CAS:Produto Controlado<p>Applications A metabolite of Desogestrel.<br>References Back, D., et al.: Br. J. Clin. Pharmacol., 26, 23 (1988), Wienkers, L., et al.: Drug Metab. Dispos., 1990, 24, 610 (1990), Bourrie, M., et al.: J. Pharmacol. Exp. Ther., 277, 321 (1996), Ono, S., et al.: Xenobiotica, 26, 681 (1996),<br></p>Fórmula:C22H30O2Cor e Forma:NeatPeso molecular:326.47Fluorometholone
CAS:Produto Controlado<p>Applications Fluorometholone is a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982), Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984),<br></p>Fórmula:C22H29FO4Cor e Forma:White To Off-WhitePeso molecular:376.461,2-Dihydro Prednicarbate
CAS:<p>Impurity Prednicarbate USP Related Compound A<br>Applications 1,2-Dihydro Prednicarbate is a related compound of Prednicarbate (P703700). Prednicarbate related compound A. Prednicarbate USP Related Compound A.<br>References Conolly, et al.: J. Chem. Soc., 828 (1937),<br></p>Fórmula:C27H38O8Cor e Forma:NeatPeso molecular:490.596β-Muethyl Prednisolone 21-Acetate (>90%)
CAS:Produto Controlado<p>Applications 6β-Μethyl Prednisolone 21-Acetate is the 6-methyl isomer of 6α-Methyl Prednisolone 21-Acetate (M326030).<br>References Sugihara, N., et al: Am. J. Cardiol., 69, 1475 (1992), Bracken, M.B., et al.: J. Neurosurg., 89, 699 (1998), Dammers, J.W.H.H., et al.: Brit. Med. J., 319, 884 (1999).<br></p>Fórmula:C24H32O6Pureza:>90%Cor e Forma:NeatPeso molecular:416.51Digoxigenin Bisdigitoxoside
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A metabolite of Digoxin (Dx) (D446575).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujii, Y., et al.: Clin. Chem., 37, 476 (1991), Salphati, L., et al.: Xenobiotica, 29, 171 (1999), Song, S., et al.: Drug Metab. Dispos., 27, 689 (1999),<br></p>Fórmula:C35H54O11Cor e Forma:NeatPeso molecular:650.80trans-Latanoprost
CAS:<p>Impurity Latanoprost USP Related Compound A<br>Stability Temperature Sensitive<br>Applications Prostaglandin analog; prodrug of active acid metabolite. It is a synthetic derivative of the natural prostaglandin PGF2α, used as an anti-glaucoma agent that is effective in various types of glaucoma and ocular hypertension. Latanoprost USP Related Compound A.<br>References Resul, B., et al.: J. Med. Chem., 36, 2242 (1993), Toris, C., et al.: Ophthalmology, 100, 1297 (1993), Holmstrom, S., et al.: Curr. Med. Res. Op., 21, 1875 (2005),<br></p>Fórmula:C26H40O5Cor e Forma:ColourlessPeso molecular:432.59Protodioscin
CAS:<p>Applications Protodioscin is a steroidal saponin compound found in a number of plant species. It is known to be the active component of the herbal aphrodisiac plant Tribulus terrestris. It has also shown to produce significant increases in the levels of the hormonal levels in animal studies.<br>References Gauthaman, K., et al.: Inter. J. Phytother. Phytopharm., 15, 44 (2008); Ganzera, M., et al.: J. Pharmac. Sci., 90(11), 1752 (2001);<br></p>Fórmula:C51H84O22Cor e Forma:Off-White To Light BeigePeso molecular:1049.20trans-Doxercalciferol
CAS:Produto Controlado<p>Applications A Vitamin D derivative.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Koeffler, M.R., et al.: Blood, 74, 82 (1989),<br></p>Fórmula:C28H44O2Cor e Forma:NeatPeso molecular:412.6521-Chloro-9-fluoro-11b,17-dihydroxy-16b-methylpregn-4-ene-3,20-dione 17-Propionate
CAS:<p>Impurity Clobetasol Propionate EP Impurity D<br>Applications 21-Chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregn-4-ene-3,20-dione 17-Propionate (Clobetasol Propionate EP Impurity D) is an impurity of Clobetasol 17-Propionate (C583500), an topical corticosteroid with anti-inflammatory properties.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),<br></p>Fórmula:C25H34ClFO5Cor e Forma:NeatPeso molecular:468.99Estrone-d2
CAS:Produto Controlado<p>Applications Isotope labelled Estrone (E889050), which is a metabolite of 17β-Estradiol (E888000). During the metabolism, it is in rapid equilibrium with Estriol (E888960) and 17β-Estradiol (E888000) (1). Causes the feminization of male fish at human and animal waste sites (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Both, D. et al.: Anal. Prof. Drug Subst. 1983 12 pp135-1892. Goodman-Gruen, D. et al.: J. Clin. Endocrinol. Metab. 1996 Aug;81(8):2999-3003.<br></p>Fórmula:C182H2H20O2Cor e Forma:Off-WhitePeso molecular:272.38Fluocinolone Acetonide-21-carboxylic Acid (>90%)
CAS:<p>Impurity Fluocinolone Acetonide EP Impurity A<br>Applications Fluocinolone Acetonide-21-carboxylic Acid, is a derivative of Fluocinolone Acetonide (F455800), which is a Corticosteroid, used in dermatology to reduce skin inflammation and relieve itching<br>References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),<br></p>Fórmula:C24H28F2O7Pureza:>90%Cor e Forma:Off WhitePeso molecular:466.47Di-Norbudesonide(Mixture of Diastereomers)
CAS:Produto Controlado<p>Impurity Budesonide EP Impurity B<br>Applications Di-Norbudesonide (Budesonide EP Impurity B) is an impurity of Budesonide (B689490), an antiinflammatory agent.<br></p>Fórmula:C23H30O6Cor e Forma:NeatPeso molecular:402.48(-)-Estra-4,9-diene-3,17-dione
CAS:Produto Controlado<p>Applications A potential metabolite of STS 557 (Dienogest)(D441870). A steroid with antiglucocorticoid activity.<br>References Kloosterboer, H., et al.: J. Steroid Biochem., 31, 567 (1988),<br></p>Fórmula:C18H22O2Cor e Forma:NeatPeso molecular:270.37Desonide 21-Acetate
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Desonide 21-Acetate is a reactant in the synthesis of 7α-halogenocorticosteroids with anti-inflammatory activity.<br>References De, K., et. al.: J. Indian Chem. Soc., 79, 513 (2002)<br></p>Fórmula:C26H34O7Cor e Forma:NeatPeso molecular:458.5417α-Hydroxy Pregnenolone-d3
CAS:Produto Controlado<p>Applications A labelled metabolite of Pregnenolone (P712200).<br>References Kramer, R., et al.: J. Steroid Biochemi., 18, 715 (1983), Hiwatashi, A., et al.: J. Biochem., 98, 619 (1985), Eiichi, T., et al.: J. Pharmacol. Sci., 95, 140 (2004),<br></p>Fórmula:C212H3H29O3Cor e Forma:NeatPeso molecular:335.50Andarine
CAS:Produto Controlado<p>Applications It is a potent and tissue-selective androgen receptor modulator (SARM) used as antiosteoporotic agent.<br>References Samnegard, E., et al.: Bone, 28, 414 (2001), Hanada, K., et al.: Biol. Pharm. Bull., 26, 1563 (2003), Kearbey, J., et al.: Xenobiotica, 34, 273 (2004), Kearbey, J., et al.: Xenobiotica, 34, 273 (2004), Kearbey, J., et al.: Pharm. Res., 24, 328 (2007),<br></p>Fórmula:C19H18F3N3O6Cor e Forma:Light YellowPeso molecular:441.36Calcipotriol Monohydrate
CAS:Produto Controlado<p>Applications Calcipotriol Monohydrate is a synthetic derivative of calcitriol, which is a biologically active form of Vitamin D3 (1). Calcipotriol Monohydrate can be used to treat psoriasis (2).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Kim, D. H., et al.: Ann Dermatol. 24, 341 (2012) (2) Queille-Roussel, C., et al.: Clin Drug Investig (2016)<br></p>Fórmula:C27H40O3·H2OCor e Forma:NeatPeso molecular:430.623-O-Methyl Estradiol
CAS:Produto Controlado<p>Applications Estradiol derivative which shows antioxidant activity.<br>References Fotsis, T., et al.: J. Steroid. Biochem., 28, 215 (1987), Sack, M., et al.: Lancet, 343, 269 (1994), Brunelli, R., et al.: Biochemistry, 39, 13897 (2000), Li, A., et al.: Nat. Med., 8, 1235 (2002),<br></p>Fórmula:C19H26O2Cor e Forma:White To Light YellowPeso molecular:286.41δ-5(6)-Norethindrone Acetate
CAS:Produto Controlado<p>Impurity Norethindrone Acetate EP Impurity C<br>Applications Δ-5(6)-Norethindrone Acetate (Norethindrone Acetate EP Impurity C) is an impurity of Norethindrone Acetate (N675990).<br></p>Fórmula:C22H28O3Cor e Forma:NeatPeso molecular:340.46Dexamethasone 21-Mesylate
CAS:Produto Controlado<p>Stability Moisture Sensitive<br>Applications Dexamethasone 21-Mesylate is a derivative of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent.<br>References Kim, T.H., et al.: J. Nanosci. Nanotech., 13, 7325 (2013); Joshi, T., et al.: Brit. J. Pharmacol., 172, 1360 (2015);<br></p>Fórmula:C23H31FO7SCor e Forma:NeatPeso molecular:470.55Chlormadinone
CAS:Produto Controlado<p>Applications It has been used in combinations as an oral contraceptive.<br>References Brennan, D.M., et al.: Acta Endocrinol., 44, 367 (1963), Honma., s., et al.: Chem Pharm. Bull., 25 2019 (1977), Usui, T., et al.: Acta Urol. Jpn., 27, 327 (1981),<br></p>Fórmula:C21H27ClO3Cor e Forma:NeatPeso molecular:362.89Digoxin
CAS:Produto Controlado<p>Applications Cardiotonic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aronson, J.K., et al.: Clin. Pharmacokinet, 5,137 (1980), Foss, P.R.B., Anal. Profiles Drug Subs., 9, 207 (1980),<br></p>Fórmula:C41H64O14Cor e Forma:WhitePeso molecular:780.94(2α)-Methyl Megestrol Acetate
CAS:Produto Controlado<p>Impurity Megestrol Acetate EP Impurity H<br>Applications (2α)-Methyl Megestrol Acetate (Megestrol Acetate EP Impurity H) is a related impurity in Megestrol acetate (M208050).<br>References Schneider, F., et al.: Helv. Chim. Acta, 56, 2396 (1973), Aisner, J., et al.: Semin. Oncol., 15, 68 (1988), Krischenowski, D., et al.: Steroids, 58, 278 (1993), Bratoeff, E., et al.: Chem. Pharm. Bull., 51, 1132 (2003),<br></p>Fórmula:C25H34O4Cor e Forma:NeatPeso molecular:398.5417α-Progesterone
CAS:<p>Applications 17α-Progesterone is a testosterone precursror generated from cholesterol. Also used as a diagnostic agent in the identification and study of ovarian Leydig cell tumor disease.<br>References Vesely, D. et al.: Proc. Natl. Acad. Sci. USA., 76, 3491 (1979); Arhan, E. et al.: J. Pediatric Endocrinol. Metab., 21, 181 (2008);<br></p>Fórmula:C21H30O2Cor e Forma:NeatPeso molecular:314.46δ7-Avenasterol (E/Z mixture)
CAS:<p>Applications Δ7-Avenasterol is an analog of Stigmasterol (S686750); a plant sterol that is used as a precursor in the synthesis of progesterone.<br>References Han, P., et al.: Biotechnol. App. Biochem., 54, 105 (2009); Matsunaga, I., et al.: Anal. Biochem., 393, 222 (2009); Huang, C., et al.: Plant Physiol., 150, 1192 (2009)<br></p>Fórmula:C29H48OCor e Forma:White To Off-WhitePeso molecular:412.6924(R/S)-Hydroxycholesterol-d7
CAS:Produto Controlado<p>Applications 24(R/S)-Hydroxycholesterol-d7 is used in the study of biochemical methods for quantitative detection of steroids containing quantitative charge tags and oxidizing agents and using mass spectroscopy for detection.<br>References Groffoths, Williams., US 20150233953, (2015)<br></p>Fórmula:C272H7H39O2Cor e Forma:NeatPeso molecular:409.70(11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:<p>Applications (11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, can be used for the synthesis of Calicoferol E, a vitamin D3 analogues.<br>References Vir Singh, T., et al.: ARKAT USA, INc., (2002);<br></p>Fórmula:C22H28O5Cor e Forma:White To Light RedPeso molecular:372.45Exemestane-19-d3
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications An antineoplastic (hormonal).<br>References Giudici, D., et al.: J. Steroid Biochem., 30, 391 (1988), Evans, T.R.J., et al.: Cancer Res., 52, 5933 (1992), Zilembo, N., et al.: Brit. J. Cancer, 72, 1007 (1995)<br></p>Fórmula:C20H21D3O2Cor e Forma:NeatPeso molecular:299.42Betamethasone 17-Propionate
CAS:Produto Controlado<p>Impurity Clobetasol Propionate EP Impurity A / Betamethasone Dipropionate EP Impurity B<br>Applications Betamethasone 17-Propionate (Clobetasol Propionate EP Impurity A) is a degradation product of Betamethasone. Glucocorticoid.<br>References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),<br></p>Fórmula:C25H33FO6Cor e Forma:Off-WhitePeso molecular:448.524-Pregnen-17α, 20α-diol-3-one
CAS:Produto ControladoFórmula:C21H32O3Cor e Forma:NeatPeso molecular:332.48Finasteride Carboxylic Acid Methyl Ester
CAS:Produto Controlado<p>Applications Finasteride Carboxylic Acid Methyl Ester is an metabolite of Finasteride (F342000), an inhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone.<br>References Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993), Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997), McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998),<br></p>Fórmula:C24H36N2O4Cor e Forma:NeatPeso molecular:416.554
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