Esteroides e Derivados
Os esteroides são compostos orgânicos que possuem uma estrutura de quatro anéis fundidos, conhecida como núcleo esteroide. Esse núcleo pode estar ligado a vários grupos funcionais que modificam suas propriedades e funções biológicas. Os esteroides desempenham um papel fundamental na regulação dos processos metabólicos e hormonais. São utilizados na medicina para tratar distúrbios inflamatórios, doenças autoimunes e desequilíbrios hormonais. Além disso, alguns derivados de esteroides possuem potentes propriedades anti-inflamatórias, como os corticosteroides. Em terapias específicas, são utilizados para reduzir a inflamação e controlar a dor em diversas doenças.
Na CymitQuimica, oferecemos uma variedade de esteroides e seus derivados para pesquisa e desenvolvimento farmacêutico.
Foram encontrados 4968 produtos de "Esteroides e Derivados"
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5-β-Pregnane-3-α,20-α-diol
CAS:<p>Applications 5β-Pregnane-3α,20α-diol is a metabolite of Progesterone (P755900).<br>References Beall, et al.: Biochem. J., 31, 35 (1937), Okuda, A., et al.: J. Biol. Chem., 259, 7519 (1984), Russell, D., et al.: Biochemistry, 31, 4737 (1992), Kondo, K., et al.: Eur. J. Biochem., 219, 357 (1994), Westerbacka, J., et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003),<br></p>Fórmula:C21H36O2Cor e Forma:White To Off-WhitePeso molecular:320.51Di-Norbudesonide(Mixture of Diastereomers)
CAS:Produto Controlado<p>Impurity Budesonide EP Impurity B<br>Applications Di-Norbudesonide (Budesonide EP Impurity B) is an impurity of Budesonide (B689490), an antiinflammatory agent.<br></p>Fórmula:C23H30O6Cor e Forma:NeatPeso molecular:402.48Limaprost-d3 (>90%)
CAS:Produto Controlado<p>Applications Labelled Limaprost (L461500). Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsuboi, T., et al.: Arch. Int. Pharmacodyn., 247, 89 (1980), Adaikan, P.G., et al.: Prostaglandins Med., 6, 449 (1981), Kottegoda, S.R., et al.: Prostaglandins Leukotrienes Med., 8, 343 (1982), Ishizaki, T., et al.: Chest, 85, 382 (1984),<br></p>Fórmula:C22H33D3O5Pureza:>90%Cor e Forma:NeatPeso molecular:383.54Formestane
CAS:Produto Controlado<p>Applications An antitumor drug. An aromatase inhibitor.<br>References Brodie, A.M. and Njar, V.C.: Steroids, 65, 171 (2000), Lonning, P.E., et al.: J. Steroid Biochem, 77, 39 (2001)<br></p>Fórmula:C19H26O3Cor e Forma:NeatPeso molecular:302.416β-Hydroxy Norethindrone Acetate
CAS:Produto Controlado<p>Impurity Norethindrone Acetate EP Impurity F<br>Applications 6β-Hydroxy Norethindrone Acetate (Norethindrone Acetate EP Impurity F) is an oxidative product of the drug Norethindrone (N676000). Norethindrone impurity.<br>References Reif, V., et al.: Pharmaceutical Res., 4, 54 (1987), Rao, P., et al.: Steroids, 59, 621 (1994),<br></p>Fórmula:C22H28O4Cor e Forma:Off-WhitePeso molecular:356.46Androst-4-ene-3,6,17-trione
CAS:Produto Controlado<p>Applications An aromatase inhibitor.<br>References Aello, A., et al.: J. Nat. Prod., 54, 281 (1991), Salaja, B.A., et al.: Steroids, 59, 330 (1994), Hunter, A.C., et al.: J. Steroid Biochem. Mol. Biol., 87, 301 (2003),<br></p>Fórmula:C19H24O3Cor e Forma:NeatPeso molecular:300.39Hydroxy Flutamide
CAS:Produto Controlado<p>Applications The active metabolite of the widely used non-steroidal antagonist Flutamide (F598850). Shown to be an antianhydrogen.<br>References Katchen, B., et al.: J. Clin. Endocrinol. Metab., 41, 373 (1975), Fau, D., et al.: J. Pharmacol. Exp. Ther., 269, 954 (1994), Anzenbacher, P., et al.: Drug Metab. Dispos., 30, 100 (2002), Norlin, M., et al.: J. Lipid Res., 43, 721 (2002),<br></p>Fórmula:C11H11F3N2O4Cor e Forma:Off White SolidPeso molecular:292.21Testosterone 17-Isocaproate
CAS:Produto Controlado<p>Applications Testosterone Isocaproate, is one of the common anabolic steroid esters. It is a controlled substance in US due to their potential for abuse and misuse. It can be used for the treatment of constitutional delayed puberty (CDP), in combination of other testosterone esters.<br>References Noggie, F. T., et al.: J. Chromatography. Sci., 28 (5), 263 (1990); Buyukgebiz, A., et al.: Hormone REs., 44 Suppl 3, 32 (1995);<br></p>Fórmula:C25H38O3Cor e Forma:White To Off-WhitePeso molecular:386.57Fluocinolone
CAS:Produto Controlado<p>Impurity Fluocinolone Acetonide EP Impurity C<br>Applications Fluocinolone, is a medication, used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin condition. It is also a derivative of Fluocinolone Acetonide (F455800).<br>References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),<br></p>Fórmula:C21H26F2O6Cor e Forma:NeatPeso molecular:412.42Etonogestrel β-D-Glucuronide
Produto Controlado<p>Applications A metabolite of Etonogestrel.<br></p>Fórmula:C28H36O8Cor e Forma:NeatPeso molecular:500.581Betamethasone Acid
CAS:Produto Controlado<p>Applications Betamethasone Acid is a derivative of Betamethasone (B327000), a gluccocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),<br></p>Fórmula:C21H27FO5Cor e Forma:NeatPeso molecular:378.4322-Hydroxy Mifepristone
CAS:Produto Controlado<p>Applications A metabolite of Mifepristone.<br>References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Fórmula:C29H35NO3Cor e Forma:NeatPeso molecular:445.596a-Methyl Prednisolone 17-Propionate
CAS:Fórmula:C25H34O6Cor e Forma:White To Off-WhitePeso molecular:430.534-Hydroxy Testosterone
CAS:Produto Controlado<p>Applications 4-Hydroxytestosterone is an anabolic steroid and does not have any therapeutic indication. 4-Hydroxytestosterone is metabolite of the aromatase inhibitor Formestane (F692250). 4-Hydroxytestosterone concentration in the urine can be used as a biomarker for steroid misuse.Controlled Substance.<br>References Kohler, M. et al.: Steroids, 72, 278 (2007); Brodie, A.M. et al.: J. Steroid. Biochem., 14, 693 (1981); Van Renterghem, P. et al.: Steroids, 75, 154 (2010);<br></p>Fórmula:C19H28O3Cor e Forma:NeatPeso molecular:304.429-Dehydrotestosterone
CAS:Produto Controlado<p>Applications 9-Dehydrotestosterone, is the analogue of Testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McFarland, K., et al.: Science, 245, 494 (1989), Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998), Themmen, A., et al.: Endocr. Rev. 21, 551 (2000), Kumar, R., et al.: Biol. Reprod., 65, 710 (2001),<br></p>Fórmula:C19H26O2Cor e Forma:NeatPeso molecular:286.41Pregnanetriol
CAS:<p>Applications Pregnanetriol is a steroid present at elevated levels in the urine of patients with congenital adrenal hyperplasma. During treatment with cortisol replacement, elevated urine Pregnanetriol levels indicate insufficient dosage of cortisol. Pregnanetriol is also one of the urinary marker for adrenal incidentaloma. Pregnanetriol is a metabolite of Androstenedione (A637550).<br>References Kinoshita, K. et al.: J. Clin. Endocrinol., 26, 1219 (1966); Kotlowska, A. et al.: Clin. Biochem., 42, 448 (2009); Wang, J. et al.: Zhipu Xue., 25, 201 (2004);<br></p>Fórmula:C21H36O3Cor e Forma:WhitePeso molecular:336.512-Nitrobenzotrifluoride
CAS:Produto Controlado<p>Applications 2-Nitrobenzotrifluoride can be used for self-repairing polyimide based on dynamic imine bond.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lei, X., et.al., Faming Zhuanli Shenqing, 15, (2019);<br></p>Fórmula:C7H4F3NO2Cor e Forma:NeatPeso molecular:191.107Testosterone Enanthate-d3
CAS:Produto Controlado<p>Applications Isotope labelled testosterone enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.<br>References Janjic, M.M., et al.: Reproduct. Toxicol., 34, 686 (2012); Lacreuse, A., et al.: Physiol. Behaviour., 106, 229 (2012);<br></p>Fórmula:C26H37D3O3Cor e Forma:Colourless To Off-WhitePeso molecular:403.61Secalciferol
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications A metabolite of Vitamin D, a possibly anti-inflammatory steroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Boyan, B., et al.: Steroids, 66, 363 (2001), Holick, M., et al.: J. Cell Biochem., 88, 296 (2003), Vogeser, M., et al.: Clin. Chem., 50, 1415 (2004), Singh, R., et al.: J. Clin. Endocrinol. Metab., 91, 3055 (2006),<br></p>Fórmula:C27H44O3Cor e Forma:NeatPeso molecular:416.64Fluocinolone Acetonide Acetate
CAS:<p>Applications Glucocorticoid; anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Brunmair, B., et al.: J. Pharmacol. Exp. Therap., 311, 109 (2004), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),<br></p>Fórmula:C26H32F2O7Cor e Forma:White To Off-WhitePeso molecular:494.521,2-Dihydro-deflazacort
CAS:Produto ControladoFórmula:C25H33NO6Cor e Forma:NeatPeso molecular:443.5336b-Hydroxy Androstenedione
CAS:Produto Controlado<p>Applications A metabolite of Androstenedione (A637550).<br>References Gazdar, A., et al.: Cancer Res., 50, 5488 (1990), Levesque, J., et al.: Steroids, 70, 305 (2005), Lootens, L., et al.: Drug Metab. Dispos., 37, 2367 (2009),<br></p>Fórmula:C19H26O3Cor e Forma:NeatPeso molecular:302.41Cholesterol 3-Acetate-d7
CAS:Produto ControladoFórmula:C29H41D7O2Cor e Forma:NeatPeso molecular:435.73cis-Diethyl Stilbestrol
CAS:<p>Stability Isomerizes rapidly in Benzene, Chloroform, and Ether.Keep Shielded from light.<br>Applications A synthetic, nonsteroidal estrogen.Recomended solvents are DMSO, DMF and ethanol, even in these solvents do not store in solution for any prolonged period of time.<br>References White, W. A. et. al.: J. Agric. Food Chem. 19(2), 388-390 (1971).<br></p>Fórmula:C18H20O2Cor e Forma:NeatPeso molecular:268.35Tibolone
CAS:Produto Controlado<p>Applications A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.<br>References de Visser, J., et al.: Arzneim.-Forsch., 34, 1010 (1984), Geusens, P., et al.: Maturitas Suppl, 1, 1 (1987)<br></p>Fórmula:C21H28O2Cor e Forma:WhitePeso molecular:312.4516a-Methyl Prednisolone
CAS:Produto Controlado<p>Applications 16α-Methylprednisolone is the 16α-Methyl analogue of Prednisolone (P703740). 16α-Methylprednisolone is an anti-inflammatory corticosteroid.<br>References Biju, P. et al.: Bioorg. Med. Chem. Lett., 22, 1086 (2012); Dausse, J.P. et al.: Mol. Pharmacol., 13, 948 (1977):<br></p>Fórmula:C22H30O5Cor e Forma:NeatPeso molecular:374.47Clobetasol Propionate Impurity E
<p>Applications Clobetasol Propionate Impurity E is an impurity of Clobetasol (C583490), which is a topical corticosteroid. Glucocorticoid; anti-inflammatory.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),<br></p>Fórmula:C25H33ClO4Cor e Forma:NeatPeso molecular:432.98Δ-5(10)-Norethindrone Acetate
CAS:Produto Controlado<p>Impurity Norethindrone Acetate EP Impurity B<br>Applications Δ-5(10)-Norethindrone Acetate (Norethindrone Acetate EP Impurity B) is a Norethindrone Acetate (N675990) impurity. Used in studies of progesterone-binding properties of purified uteroglobin-like protein.<br>References Beato, M. et al.: J. Reprod. Fert., 53, 305 (1978); Schroff, A. P., et al.: Anal. Profiles Drug Subs., 4, 268 (1975); Singh, H., et al.: Am. J. Obstet. Gynecol., 135, 409 (1979);<br></p>Fórmula:C22H28O3Cor e Forma:Off-WhitePeso molecular:340.46Betamethasone 21-O-Ethyl Carbonate
CAS:Produto Controlado<p>Impurity Betamethasone EP Impurity D<br>Applications Betamethasone 21-O-Ethyl Carbonate (Betamethasone EP Impurity D) is a derivative of Betamethasone (B327000); a glucocorticoid used as an anti-inflammatory agent.4<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977); Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002); Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005); Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006); Xiong, Y., et al.: J. Pharmaceut. Biomed., 49, 646 (2009)<br></p>Fórmula:C25H33FO7Cor e Forma:NeatPeso molecular:464.52Triamcinolone Furetonide
CAS:Produto ControladoFórmula:C33H35FO8Cor e Forma:NeatPeso molecular:578.62Flurandrenolone Acetate
CAS:<p>Impurity Fluocinolone Acetonide EP Impurity G<br>Applications Flurandrenolone Acetate, is the derivative of Flurandrenolide (F598650), which is a Glucocorticoid, used as an antipsoriatic.<br>References Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984), Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),<br></p>Fórmula:C26H35FO7Cor e Forma:NeatPeso molecular:478.5520(R)-Hydroxy Prednisolone
CAS:Produto Controlado<p>Applications Prednisolone (P703740) metabolite.<br>References Garg, V., et al.: Biopharm. Drug Disposition, 15, 163 (1994), Adham, N., et al.: Proc. Biochem., 38, 897 (2003),<br></p>Fórmula:C21H30O5Cor e Forma:Off-WhitePeso molecular:362.46Latanoprost
CAS:<p>Applications Prostaglandin analog, used to treat glaucoma and other degenerative diseases of the eye.<br>References Rhee, D.J., et al.: Clinic. Ophthalmol., 2, 313 (2008), Hernandez, M., et al.: Exp. Eye Res., 86, 798 (2008), Nagata, T., et al.: J. Pharmacol. Sci., 106, 423 (2008), Ikeda, Y., et al.: J. Ocular Pharmacol. Ther., 24, 230 (2008),<br></p>Fórmula:C26H40O5Cor e Forma:Light YellowPeso molecular:432.59Dienogest-d8 (major)
CAS:Produto Controlado<p>Applications Dienogest-d8 (major) is labelled derivative of 19-Nortestosterone. It is used in combination with estrogen as oral contraceptive.<br>References Hubner, M., et al.: Arzneim.-Forsch., 30, 401 (1980), Spona, J., et al.: Contraception, 56, 185 (1997), Foster, R.H., et al.: Drugs, 56, 825 (1998)<br></p>Fórmula:C20H17D8NO2Cor e Forma:Light YellowPeso molecular:319.47Paricalcitol
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Synthetic analog of vitamin D. Antihyperparathyroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sidek, H., et al.: Biochim. Biophys. Acta, 801, 26 (1984), Ciftci, M., et al.: J. Pharmacol., 54, 275 (2002),<br></p>Fórmula:C27H44O3Cor e Forma:NeatPeso molecular:416.64Pregnenolone monosulfate
CAS:<p>Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a potent nootropic steroid used in the study of neuroticism and depression.</p>Fórmula:C21H32O5SPureza:99.46%Cor e Forma:SolidPeso molecular:396.5417-epi-Testosterone
CAS:Produto Controlado<p>Applications Testosterone and epitestosterone are endogenous steroids that differ in the configuration of the hydroxyl-bearing carbon at C-17. Testosterone is the predominant male sex hormone, whereas the role of epitestosterone is largely unclear. In humans, both androgens are excreted mainly as glucuronide conjugates.<br>References Wudy, S., et al.: Steroids, 66, 759 (2001), Kootstra, P., et al.: Anal. Chim. Acta., 586, 82 (2007), Sten, T., et al.: Drug Metab. Dispos., 37, 417 (2009),<br></p>Fórmula:C19H28O2Cor e Forma:White To Light YellowPeso molecular:288.42Alphadolone
CAS:Produto Controlado<p>Applications Alphadolone or Alfadolone (INN) is a neuroactive steroid with hypnotic effects. Alphadolone is one of the components of Althesin.<br>References Harrison, N., et al.: J. Pharmacol. Exp. Ther., 241, 346 (1987), Serrao, J., et al.: Anesthesiology, 70, 780 (1989), Mistry, D., et al.: Exp. Physiol., 75, 199 (1900),<br></p>Fórmula:C21H32O4Cor e Forma:NeatPeso molecular:348.48Lasofoxifene
CAS:<p>Applications A next-generation selective estrogen receptor modulator for treating disorders associated with increased bone turnover and osteopenia.<br>References Baumann, R., et al.: Biochem. Pharmacol., 55, 841 (1998), Ammann, P., et al.: Osteoporos Int., 10, 369 (1999), Alexandersen, P., et al.: J. Clin. Endocrinol. Metab., 86, 755 (2001), Bourrin, S., et al.: Bone, 30, 195 (2002), Buzdar, A., et al.: J. Clin. Oncol., 21, 1007 (2003),<br></p>Fórmula:C28H31NO2Cor e Forma:NeatPeso molecular:413.55Betamethasone 11,21-Diacetate
CAS:Produto Controlado<p>Impurity Betamethasone Acetate EP Impurity C<br>Applications Betamethasone 11β,21-Diacetate is an impurity of Betamethasone 21-Acetate (B327025); a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.<br>References Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001); Seidler, J., et al.: J. Med. Chem., 46, 4477 (2003); Alsenz, J., et al.: J. Pharm. Sci., 96, 1748 (2007)<br></p>Fórmula:C26H33FO7Cor e Forma:WhitePeso molecular:476.53Digoxigenin Monodigitoxoside
CAS:Produto Controlado<p>Applications A metabolite of Digoxin (Dx) (D446575).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujii, Y., et al.: Clin. Chem., 37, 476 (1991), Salphati, L., et al.: Xenobiotica, 29, 171 (1999), Song, S., et al.: Drug Metab. Dispos., 27, 689 (1999),<br></p>Fórmula:C29H44O8Cor e Forma:BeigePeso molecular:520.65Estradiol Enanthate
CAS:<p>Applications Estradiol Enanthate has been used as an injectable contraceptive.<br>References Coutinho, E.M., et. al.: Contraception, 73, 249 (2006)<br></p>Fórmula:C25H36O3Cor e Forma:BeigePeso molecular:384.555(6)-Dehydro-4(5)-dihydro D-(-)-Norgestrel (>90%)
CAS:Produto Controlado<p>Impurity Levonorgestrel EP Impurity P<br>Applications 5(6)-Dehydro-4(5)-dihydro D-(-)-Norgestrel (Levonorgestrel EP Impurity P) is a Norgestrel (N689500) impurity.<br></p>Fórmula:C21H28O2Pureza:>90%Cor e Forma:NeatPeso molecular:312.45Corticosterone
CAS:Produto Controlado<p>Applications Glucocorticoid; an intermediate in the biosynthesis of aldosterone, isolated from the adrenal cortex.<br>References Schmidt, M., et al.: Endocrinol., 150, 2709 (2009), Bailey, M., et al.: J. Immunol., 182, 7888 (2009), Brunton, P., et al.: J. Neurosci., 29, 6449 (2009), Pruett, S., et al.: Toxicol. Sci., 109, 265 (2009),<br></p>Fórmula:C21H30O4Cor e Forma:NeatPeso molecular:346.4611-Deoxy Prednisolone
CAS:Produto Controlado<p>Impurity Prednisolone EP Impurity J<br>Applications 11-Deoxy Prednisolone (Prednisolone EP Impurity J) is a Prednisolone (P703740) derivative as a corticosteroid.<br>References Kobayashi, Y., et al.: Biol. Pharm. Bull., 16, 1175 (1993), Ogata, M., et al.: J. Pharm. Sci., 87, 91 (1998), Hou, S., et al.: J. Pharm. Biomed. Anal., 24, 371 (2001),<br></p>Fórmula:C21H28O4Cor e Forma:Light BrownPeso molecular:344.44
